Abstract: Human genome is not only the evolutionary
summation of all advantageous events, but also houses lesions of
deleterious foot prints. A single gene mutation sometimes may
express multiple consequences in numerous tissues and a linear
relationship of the genotype and the phenotype may often be obscure.
ß Thalassemia minor, a transfusion independent mild anaemia,
coupled with environment among other factors may articulate into
phenotypic pleotropy with Hypocholesterolemia, Vitamin D
deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological
alterations. Occurrence of Pancreatic insufficiency, resultant
steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with
Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor
patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2
4.60% and Hb Adult 84.80% and altered Hemogram) with increased
Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2
(9.5mg/ml) indicate towards a cascade of phenotypic pleotropy
where the ß Thalassemia mutation ,be it in the 5’ cap site of the
mRNA , differential splicing etc in heterozygous state is effecting
several metabolic pathways. Compensatory extramedulary
hematopoiesis may not coped up well with the stressful life style of
the young individual and increased erythropoietic stress with high
demand for cholesterol for RBC membrane synthesis may have
resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia
may have caused the pancreatic insufficiency, leading to Vitamin D
deficiency. This may in turn have caused the secondary
hyperparathyroidism to sustain serum Calcium level. Irritability and
stress intolerance of the patient was a cumulative effect of the vicious
cycle of metabolic compromises. From these findings we propose
that the metabolic deficiencies in the ß Thalassemia mutations may
be considered as the phenotypic display of the pleotropy to explain
the genetic epidemiology.
According to the recommendations from the NIH Workshop on
Gene-Environment Interplay in Common Complex Diseases: Forging
an Integrative Model, study design of observations should be
informed by gene-environment hypotheses and results of a study
(genetic diseases) should be published to inform future hypotheses.
Variety of approaches is needed to capture data on all possible
aspects, each of which is likely to contribute to the etiology of
disease. Speakers also agreed that there is a need for development of
new statistical methods and measurement tools to appraise
information that may be missed out by conventional method where
large sample size is needed to segregate considerable effect.
A meta analytic cohort study in future may bring about significant
insight on to the title comment.
Abstract: In communication networks where communication nodes are connected with finite capacity transmission links, the packet inter-arrival times are strongly correlated with the packet length and the link capacity (or the packet service time). Such correlation affects the system performance significantly, but little attention has been paid to this issue. In this paper, we propose a mathematical framework to study the impact of the correlation between the packet service times and the packet inter-arrival times on system performance. With our mathematical model, we analyze the system performance, e.g., the unfinished work of the system, and show that the correlation affects the system performance significantly. Some numerical examples are also provided.
Abstract: Factor analysis was applied to two stages biogas
production from banana stem waste allowing a screening of the
experimental variables second stage temperature (T), organic loading
rates (OLR) and hydraulic retention times (HRT). Biogas production
was found to be strongly influenced by all the above experimental
variables. Results from factorial analysis have shown that all
variables which were HRT, OLR and T have significant effect to
biogas production. Increased in HRT and OLR could increased the
biogas yield. The performance was tested under the conditions of
various T (35oC-60oC), OLR (0.3 g TS/l.d–1.9 gTS/l.d), and HRT (3
d–15 d). Conditions for temperature, OLR and HRT in this study
were based on the best range obtained from literature review.
Abstract: SIP (Session Initiation Protocol), using HTML based
call control messaging which is quite simple and efficient, is being
replaced for VoIP networks recently. As for authentication and
authorization purposes there are many approaches and considerations
for securing SIP to eliminate forgery on the integrity of SIP
messages. On the other hand Elliptic Curve Cryptography has
significant advantages like smaller key sizes, faster computations on
behalf of other Public Key Cryptography (PKC) systems that obtain
data transmission more secure and efficient. In this work a new
approach is proposed for secure SIP authentication by using a public
key exchange mechanism using ECC. Total execution times and
memory requirements of proposed scheme have been improved in
comparison with non-elliptic approaches by adopting elliptic-based
key exchange mechanism.
Abstract: The use of neural networks is popular in various
building applications such as prediction of heating load, ventilation
rate and indoor temperature. Significant is, that only few papers deal
with indoor carbon dioxide (CO2) prediction which is a very good
indicator of indoor air quality (IAQ). In this study, a data-driven
modelling method based on multilayer perceptron network for indoor
air carbon dioxide in an apartment building is developed.
Temperature and humidity measurements are used as input variables
to the network. Motivation for this study derives from the following
issues. First, measuring carbon dioxide is expensive and sensors
power consumptions is high and secondly, this leads to short
operating times of battery-powered sensors. The results show that
predicting CO2 concentration based on relative humidity and
temperature measurements, is difficult. Therefore, more additional
information is needed.
Abstract: The frequency dependence of the phase field
model(PFM) is studied. A simple PFM is proposed, and is tested in a
laminar boundary layer. The Blasius-s laminar boundary layer
solution on a flat plate is used for the flow pattern, and several
frequencies are imposed on the PFM, and the decay times of the
interfaces are obtained. The computations were conducted for three
cases: 1) no-flow, and 2) a half ball on the laminar boundary layer, 3) a
line of mass sources in the laminar boundary layer. The computations
show the decay time becomes shorter as the frequency goes larger, and
also show that it is sensitive to both background disturbances and
surface tension parameters. It is concluded that the proposed simple
PFM can describe the properties of decay process, and could give the
fundamentals for the decay of the interface in turbulent flows.
Abstract: It has become crucial over the years for nations to
improve their credit scoring methods and techniques in light of the
increasing volatility of the global economy. Statistical methods or
tools have been the favoured means for this; however artificial
intelligence or soft computing based techniques are becoming
increasingly preferred due to their proficient and precise nature and
relative simplicity. This work presents a comparison between Support
Vector Machines and Artificial Neural Networks two popular soft
computing models when applied to credit scoring. Amidst the
different criteria-s that can be used for comparisons; accuracy,
computational complexity and processing times are the selected
criteria used to evaluate both models. Furthermore the German credit
scoring dataset which is a real world dataset is used to train and test
both developed models. Experimental results obtained from our study
suggest that although both soft computing models could be used with
a high degree of accuracy, Artificial Neural Networks deliver better
results than Support Vector Machines.
Abstract: This paper is concerned with propagation of thermoelastic longitudinal vibrations of an infinite circular cylinder, in the context of the linear theory of generalized thermoelasticity with two relaxation time parameters (Green and Lindsay theory). Three displacement potential functions are introduced to uncouple the equations of motion. The frequency equation, by using the traction free boundary conditions, is given in the form of a determinant involving Bessel functions. The roots of the frequency equation give the value of the characteristic circular frequency as function of the wave number. These roots, which correspond to various modes, are numerically computed and presented graphically for different values of the thermal relaxation times. It is found that the influences of the thermal relaxation times on the amplitudes of the elastic and thermal waves are remarkable. Also, it is shown in this study that the propagation of thermoelastic longitudinal vibrations based on the generalized thermoelasticity can differ significantly compared with the results under the classical formulation. A comparison of the results for the case with no thermal effects shows well agreement with some of the corresponding earlier results.
Abstract: An important step in three-dimensional reconstruction
and computer vision is camera calibration, whose objective is to
estimate the intrinsic and extrinsic parameters of each camera. In this
paper, two linear methods based on the different planes are given. In
both methods, the general plane is used to replace the calibration
object with very good precision. In the first method, after controlling
the camera to undergo five times- translation movements and taking
pictures of the orthogonal planes, a set of linear constraints of the
camera intrinsic parameters is then derived by means of homography
matrix. The second method is to get all camera parameters by taking
only one picture of a given radius circle. experiments on simulated
data and real images,indicate that our method is reasonable and is a
good supplement to camera calibration.
Abstract: A comparative evaluation of acute toxicity of
synthesized nano silvers using two different procedures (biological
and chemical reduction methods) and silver ions on bacteria
Vibrio fischeri was investigated. The bacterial light inhibition test as
a toxicological endpoint was used by applying of a homemade
luminometer. To compare the toxicity effects as a quantitative
parameter, a nominal effective concentrations (EC) of chemicals and
a susceptibility constant (Z-value) of bacteria, after 5 min and 30 min
exposure times, were calculated. After 5 and 30 min contact times,
the EC50 values of two silver nanoparticles and the EC20 values were
about similar. It demonstrates that toxicity of silvers was independent
of their procedure. The EC values of nanoparticles were larger than
those of the silver ions. The susceptibilities(Z- Values) of V.fischeri
(L/mg) to the silver ions were greater than those of the nano silvers.
According to the EC and Z values, the toxicity of silvers decreased in
the following order: Silver ions >> silver nanoparticles from
chemical reduction method ~ silver nanoparticles from biological
method.
Abstract: This study aims to analyze the effect of e-learning on
photonics technology and daily livings among college students. The
course contents of photonics technology and daily livings are first
drafted based on research discussions and expert interviews. Having
expert questionnaires with Delphi Technique for three times, the
knowledge units and items for the course of photonics technology and
daily livings are established. The e-learning materials and the drafts of
instructional strategies, academic achievement, and learning attitude
scales are then developed. With expert inspection, reliability and
validity test, and experimental instructions, the scales and the material
are further revised. Finally, the formal instructions are implemented to
test the effect of different instructional methods on the academic
achievement of photonics technology and daily livings among students
in universities of technology. The research results show that e-learning
could effectively promote academic achievement and learning
attitude, and the students with e-learning obviously outperform the
ones with trandition instructions.
Abstract: In this paper, multi-processors job shop scheduling problems are solved by a heuristic algorithm based on the hybrid of priority dispatching rules according to an ant colony optimization algorithm. The objective function is to minimize the makespan, i.e. total completion time, in which a simultanous presence of various kinds of ferons is allowed. By using the suitable hybrid of priority dispatching rules, the process of finding the best solution will be improved. Ant colony optimization algorithm, not only promote the ability of this proposed algorithm, but also decreases the total working time because of decreasing in setup times and modifying the working production line. Thus, the similar work has the same production lines. Other advantage of this algorithm is that the similar machines (not the same) can be considered. So, these machines are able to process a job with different processing and setup times. According to this capability and from this algorithm evaluation point of view, a number of test problems are solved and the associated results are analyzed. The results show a significant decrease in throughput time. It also shows that, this algorithm is able to recognize the bottleneck machine and to schedule jobs in an efficient way.
Abstract: Since dealing with high dimensional data is
computationally complex and sometimes even intractable, recently
several feature reductions methods have been developed to reduce
the dimensionality of the data in order to simplify the calculation
analysis in various applications such as text categorization, signal
processing, image retrieval, gene expressions and etc. Among feature
reduction techniques, feature selection is one the most popular
methods due to the preservation of the original features.
In this paper, we propose a new unsupervised feature selection
method which will remove redundant features from the original
feature space by the use of probability density functions of various
features. To show the effectiveness of the proposed method, popular
feature selection methods have been implemented and compared.
Experimental results on the several datasets derived from UCI
repository database, illustrate the effectiveness of our proposed
methods in comparison with the other compared methods in terms of
both classification accuracy and the number of selected features.
Abstract: The electrochemical coagulation of a kaolin
suspension was investigated at the currents of 0.06, 0.12, 0.22, 0.44,
0.85 A (corresponding to 0.68, 1.36, 2.50, 5.00, 9.66 mA·cm-2,
respectively) for the contact time of 5, 10, 20, 30, and 50 min. The
TSS removal efficiency at currents of 0.06 A, 0.12 A and 0.22 A
increased with the amount of iron generated by the sacrificial anode,
while the removal efficiencies did not increase proportionally with
the amount of iron generated at the currents of 0.44 and 0.85 A,
where electroflotation was clearly observed. Zeta potential
measurement illustrated the presence of the highly positive charged
particles created by sorption of highly charged polymeric metal
hydroxyl species onto the negative surface charged kaolin particles at
both low and high applied currents. The disappearance of the
individual peaks after certain contact times indicated the attraction
between these positive and negative charged particles causing
agglomeration. It was concluded that charge neutralization of the
individual species was not the only mechanism operating in the
electrocoagulation process at any current level, but electrostatic
attraction was likely to co-operate or mainly operate.
Abstract: Cow milk, is a product of the mammary gland and
soymilk is a beverage made from soybeans; it is the liquid that
remains after soybeans are soaked. In this research effort, we
compared nutritional parameters of this two kind milk such as total
fat, fiber, protein, minerals (Ca, Fe and P), fatty acids, carbohydrate,
lactose, water, total solids, ash, pH, acidity and calories content in
one cup (245 g). Results showed soymilk contains 4.67 grams of fat,
0.52 of fatty acids, 3.18 of fiber, 6.73 of protein, 4.43 of
carbohydrate, 0.00 of lactose, 228.51 of water, 10.40 of total solids
and 0.66 of ash, also 9.80 milligrams of Ca, 1.42 of Fe, and 120.05 of
P, 79 Kcal of calories, pH=6.74 and acidity was 0.24%. Cow milk
contains 8.15 grams of fat, 5.07 of fatty acids, 0.00 of fiber, 8.02 of
protein, 11.37 of carbohydrate, ´Çá4.27 of lactose, 214.69 of water,
12.90 of total solids, 1.75 of ash, 290.36 milligrams of Ca, 0.12 of
Fe, and 226.92 of P, 150 Kcal of calories, pH=6.90 and acidity was
0.21% . Soy milk is one of plant-based complete proteins and cow
milk is a rich source of nutrients as well. Cow milk is containing near
twice as much fat as and ten times more fatty acids do soymilk. Cow
milk contains greater amounts of mineral (except Fe) it contain more
than three hundred times the amount of Ca and nearly twice the
amount of P as does soymilk but soymilk contains more Fe (ten time
more) than does cow milk. Cow milk and soy milk contain nearly
identical amounts of protein and water and fiber is a big plus, dairy
has none. Although what we choose to drink is really a mater of
personal preference and our health objectives but looking at the
comparison, soy looks like healthier choices.
Abstract: The common practice of operating S-rotor is in an
open environment; however there are times when the rotor is
installed in a bounded environment and there might be changes in the
performance of the rotor. This paper presents the changes in the
performance of S-rotor when operated in bounded flows. The
investigation was conducted experimentally to compare the
performance of the rotors in bounded environment against open
environment. Three different rotors models were designed, fabricated
and subjected to experimental measurements. All of the three models
were having 600 mm height and 300 mm Diameter. They were tested
in three different flow environments; namely: partially bounded
environment, fully bounded environment and open environment.
Rotors were found to have better starting up capabilities when
operated in bounded environment. Apart from that, all rotors manage
to achieve higher Power and Torque Coefficients at a higher Tip
Speed Ratio as compared to the open environment.
Abstract: Enterprises need a strategic plan to retain their skillful employees and provide their career management, sustain their existence, to have growth and leadership qualities, to reach the objectives to increase the value of the enterprise and to not to be affected from changing demographic structure. In the cases when the long term career expectations of skillful employees are in integrity with the enterprise’s interests, skill management process is directly related to the career management. With a long term plan, the enterprises should cover the labor force need that may arise in the future by using systematic career development programs and be prepared against developments for all times. Skill management is considered as a practice with which career mobility is planned for the skillful employee to be prepared for high level positions. Career planning is the planning of an employee’s progress or promotion within an organization for which he works by developing his knowledge, skills, abilities and motives. Career planning is considered as an individual’s planning his future and the position which he wants to have, the area which he want to work in, the objectives which he want to reach. With the aim of contributing the abovementioned discussion process, career management concept and its perception manner are examined in this study in a comparative manner.
Abstract: Currently in many major cities, public transit schedules
are disseminated through lists of routes, grids of stop times and
static maps. This paper describes a web based geographic information
system which disseminates the same schedule information through
intuitive GIS techniques. Using data from Calgary, Canada, an map
based interface has been created to allow users to see routes, stops and
moving buses all at once. Zoom and pan controls as well as satellite
imagery allows users to apply their personal knowledge about the
local geography to achieve faster, and more pertinent transit results.
Using asynchronous requests to web services, users are immersed
in an application where buses and stops can be added and removed
interactively, without the need to wait for responses to HTTP requests.
Abstract: This study examined the effects of 8-week Pilates training program on limits of stability (LOS) and abdominal muscle strength in young dancers. Twenty-four female volunteered and randomly assigned as experimental group (EG) or control group (CG). All subjects received the same dance lessons but the EG underwent an extra Pilates mat exercises for 40 minutes, three times a week, for 8 weeks. LOS was evaluated by the Biodex Balance System and the abdominal strength was measured by 30/60 seconds sit-ups test. One factor ANCOVA was used to examine the differences between groups after training. The results showed that the overall LOS scores at levels 2/8 and the 30/60 seconds sit-ups for the EG group pre- and post-training were changed from 22/38 % to 31/51 % and 20/33 times to 24/42 times, respectively. The study demonstrated that 8-week Pilates training can improve the LOS performance and abdominal strength in young dancers.
Abstract: For scores of years now, several microfinance
organizations, non governmental organizations and other welfare
organizations have, with a view to aiding the progress of
communities rooted in poverty have been focusing on creating
microentrepreneurs, besides taking several other measures. In recent
times, business corporations have joined forces to combat poverty by
taking up microenterprise development. Hindustan Unilever Limited
(HUL), the Indian subsidiary of Unilever Limited exemplifies this
through its Project Shakti. The company through the Project creates
rural women entrepreneurs by making them direct to home sales
distributors of its products in villages that have thus far been ignored
by multinational corporations. The members participating in Project
Shakti are largely self help group members. The paper focuses on
assessing the impact made by the company on the members engaged
in Project Shakti. The analysis involves use of quantitative methods
to study the effect of Project Shakti on those self help group
members engaged in Project Shakti and those not engaged with
Project Shakti. Path analysis has been used to study the impact made
on those members engaged in Project Shakti. Significant differences
were observed on fronts of entrepreneurial development, economic
empowerment and social empowerment between members associated
with Project Shakti and those not associated with Project Shakti.
Path analysis demonstrated that involvement in Project Shakti led to
entrepreneurial development resulting in economic empowerment
that in turn led to social empowerment and that these three elements
independently induced a feeling of privilege in the women for being
associated with the Project.