Abstract: Mendelian Disease Genes represent a collection of single points of failure for the various systems they constitute. Such genes have been shown, on average, to encode longer proteins than 'non-disease' proteins. Existing models suggest that this results from the increased likeli-hood of longer genes undergoing mutations. Here, we show that in saturated mutagenesis experiments performed on model organisms, where the likelihood of each gene mutating is one, a similar relationship between length and the probability of a gene being lethal was observed. We thus suggest an extended model demonstrating that the likelihood of a mutated gene to produce a severe phenotype is length-dependent. Using the occurrence of conserved domains, we bring evidence that this dependency results from a correlation between protein length and the number of functions it performs. We propose that protein length thus serves as a proxy for protein cardinality in different networks required for the organism's survival and well-being. We use this example to argue that the collection of Mendelian Disease Genes can, and should, be used to study the rules governing systems vulnerability in living organisms.
Abstract: This paper proposes a fast tree join scheme to provide
seamless multicast handover in the mobile networks based on the Fast
Mobile IPv6 (FMIPv6). In the existing FMIPv6-based multicast
handover scheme, the bi-directional tunnelling or the remote
subscription is employed with the packet forwarding from the previous
access router (AR) to the new AR. In general, the remote subscription
approach is preferred to the bi-directional tunnelling one, since in the
remote subscription scheme we can exploit an optimized multicast
path from a multicast source to many mobile receivers. However, in
the remote subscription scheme, if the tree joining operation takes a
long time, the amount of data packets to be forwarded and buffered for
multicast handover will increase, and thus the corresponding buffer
may overflow, which results in severe packet losses. In order to reduce
these costs associated with packet forwarding and buffering, this paper
proposes the fast join to multicast tree, in which the new AR will join
the multicast tree as fast as possible, so that the new multicast data
packets can also arrive at the new AR, by which the packet forwarding
and buffering costs can be reduced. From numerical analysis, it is
shown that the proposed scheme can give better performance than the
existing FMIPv6-based multicast handover schemes in terms of the
multicast packet delivery costs.
Abstract: Coloured Petri net (CPN) has been widely adopted in various areas in Computer Science, including protocol specification, performance evaluation, distributed systems and coordination in multi-agent systems. It provides a graphical representation of a system and has a strong mathematical foundation for proving various properties. This paper proposes a novel representation of a coloured Petri net using an extension of logic programming called abductive logic programming (ALP), which is purely based on classical logic. Under such a representation, an implementation of a CPN could be directly obtained, in which every inference step could be treated as a kind of equivalence preserved transformation. We would describe how to implement a CPN under such a representation using common meta-programming techniques in Prolog. We call our framework CPN-LP and illustrate its applications in modeling an intelligent agent.
Abstract: A model to identify the lifetime of target tracking
wireless sensor network is proposed. The model is a static clusterbased
architecture and aims to provide two factors. First, it is to
increase the lifetime of target tracking wireless sensor network.
Secondly, it is to enable good localization result with low energy
consumption for each sensor in the network. The model consists of
heterogeneous sensors and each sensing member node in a cluster
uses two operation modes–active mode and sleep mode. The
performance results illustrate that the proposed architecture consumes
less energy and increases lifetime than centralized and dynamic
clustering architectures, for target tracking sensor network.
Abstract: Due to the Rapid Urbanization in China, the influence of metropolises to surrounding areas grows by a tremendous speed in developed region. One of the most obvious influences is the expansion of the urban built-up areas which covers the land belongs to small towns. Around metropolitan fringe, the boundary between city and village becomes more and more obscure. So being the most sensitive area, the small towns on the fringe of metropolises have the special meaning on the research into the small towns- development. This paper chooses Sandun Town in Hangzhou of Zhejiang Province as an example, emphatically focus on aspects such as the central area proliferation, the industrial shift, the position effect, the subway effect and the commercial development, reviews a few problems of small towns in the future and the important problems in their planning by the analysis of the characteristics of the present conditions and the developing motive mechanism, so that guides small towns to develop properly by liking with these small towns and center metropolises.
Abstract: The purpose of this paper is applied Taguchi method on the optimization for PEMFC performance, and a representative Computational Fluid Dynamics (CFD) model is selectively performed for statistical analysis. The studied factors in this paper are pressure of fuel cell, operating temperature, the relative humidity of anode and cathode, porosity of gas diffusion electrode (GDE) and conductivity of GDE. The optimal combination for maximum power density is gained by using a three-level statistical method. The results confirmed that the robustness of the optimum design parameters influencing the performance of fuel cell are founded by pressure of fuel cell, 3atm; operating temperature, 353K; the relative humidity of anode, 50%; conductivity of GDE, 1000 S/m, but the relative humidity of cathode and porosity of GDE are pooled as error due to a small sum of squares. The present simulation results give designers the ideas ratify the effectiveness of the proposed robust design methodology for the performance of fuel cell.
Abstract: Although the level crossing concept has been the subject of intensive investigation over the last few years, certain problems of great interest remain unsolved. One of these concern is distribution of threshold levels. This paper presents a new threshold level allocation schemes for level crossing based on nonuniform sampling. Intuitively, it is more reasonable if the information rich regions of the signal are sampled finer and those with sparse information are sampled coarser. To achieve this objective, we propose non-linear quantization functions which dynamically assign the number of quantization levels depending on the importance of the given amplitude range. Two new approaches to determine the importance of the given amplitude segment are presented. The proposed methods are based on exponential and logarithmic functions. Various aspects of proposed techniques are discussed and experimentally validated. Its efficacy is investigated by comparison with uniform sampling.
Abstract: Resource discovery is one of the chief services of a grid. A new approach to discover the provenances in grid through learning automata has been propounded in this article. The objective of the aforementioned resource-discovery service is to select the resource based upon the user-s applications and the mercantile yardsticks that is to say opting for an originator which can accomplish the user-s tasks in the most economic manner. This novel service is submitted in two phases. We proffered an applicationbased categorization by means of an intelligent nerve-prone plexus. The user in question sets his or her application as the input vector of the nerve-prone nexus. The output vector of the aforesaid network limns the appropriateness of any one of the resource for the presented executive procedure. The most scrimping option out of those put forward in the previous stage which can be coped with to fulfill the task in question is picked out. Te resource choice is carried out by means of the presented algorithm based upon the learning automata.
Abstract: A big organization may have multiple branches spread across different locations. Processing of data from these branches becomes a huge task when innumerable transactions take place. Also, branches may be reluctant to forward their data for centralized processing but are ready to pass their association rules. Local mining may also generate a large amount of rules. Further, it is not practically possible for all local data sources to be of the same size. A model is proposed for discovering valid rules from different sized data sources where the valid rules are high weighted rules. These rules can be obtained from the high frequency rules generated from each of the data sources. A data source selection procedure is considered in order to efficiently synthesize rules. Support Equalization is another method proposed which focuses on eliminating low frequency rules at the local sites itself thus reducing the rules by a significant amount.
Abstract: Geopolymer cement was evaluated as wellbore sealing material for carbon dioxide geosequestration application. Curing of cement system in saline water and strength testing in triaxial stress state condition under lateral confinement is relevant to primary cementing in CO2 geosequestration wellbore in saline aquifer. Geopolymer cement was cured in saline water (both at ambient conditions for 28 days and heated (60°C) conditions for 12 hours) and tested for triaxial strength at different levels of lateral confinement. Normal water and few other curing techniques were also studied both for geopolymer and API ‘G’ cement. Results reported were compared to evaluate the suitability of saline water for curing of geopolymer cement. Unconfined compression test results showed higher strength for curing in saline water than normal water. Besides, testing strength under lateral confinement demonstrated the material failure behavior from brittle to plastic.
Abstract: A potentially serious problem with current payment systems is that their underlying hard problems from number theory may be solved by either a quantum computer or unanticipated future advances in algorithms and hardware. A new quantum payment system is proposed in this paper. The suggested system makes use of fundamental principles of quantum mechanics to ensure the unconditional security without prior arrangements between customers and vendors. More specifically, the new system uses Greenberger-Home-Zeilinger (GHZ) states and Quantum Key Distribution to authenticate the vendors and guarantee the transaction integrity.
Abstract: In today-s competitive global business environment,
the concept of supply chain management (SCM) continues to become
increasingly market-oriented, shifting the primary driver of the value
chain from supply to demand. Recent recommendations encourage
researchers to focus investigations on the supply chain process
integration (SCPI) capabilities that integrate a focal firm with its
network of suppliers and business customers to create value for it.
However, theoretical and empirical researches pertaining to the
antecedents and consequences of a focal firm-s SCPI capabilities have
been limited and piecemeal. The purpose of this study is to investigate
the critical determinants and consequences of a focal firm-s SCPI
capabilities. We test our proposed research framework using a sample
of 139 sales managers of manufacturing industries in Taiwan, our
research findings show that (1) both perceived business customer-s
power and focal firm-s market-oriented culture positively influences a
focal firm-s SCPI capabilities, and (2) SCPI capabilities positively
influence a focal firm-s SCM performance, both operational and
strategic benefits. Implications for practitioners and researchers and
suggestions for future research are also addressed in this study.
Abstract: A prototype of an anomaly detection system was
developed to automate process of recognizing an anomaly of
roentgen image by utilizing fuzzy histogram hyperbolization image
enhancement and back propagation artificial neural network.
The system consists of image acquisition, pre-processor, feature
extractor, response selector and output. Fuzzy Histogram
Hyperbolization is chosen to improve the quality of the roentgen
image. The fuzzy histogram hyperbolization steps consist of
fuzzyfication, modification of values of membership functions and
defuzzyfication. Image features are extracted after the the quality of
the image is improved. The extracted image features are input to the
artificial neural network for detecting anomaly. The number of nodes
in the proposed ANN layers was made small.
Experimental results indicate that the fuzzy histogram
hyperbolization method can be used to improve the quality of the
image. The system is capable to detect the anomaly in the roentgen
image.
Abstract: We have fabricated a-IGZO TFT and investigated the
stability under positive DC and AC bias stress. The threshold voltage
of a-IGZO TFT shifts positively under those biases, and that reduces
on-current. For this reason, conventional shift-register circuit
employing TFTs which stressed by positive bias will be unstable, may
do not work properly. We have designed a new 6-transistor
shift-register, which has less transistors than prior circuits. The TFTs
of the proposed shift-register are not suffering from positive DC or AC
stress, mainly kept unbiased. Despite the compact design, the stable
output signal was verified through the SPICE simulation even under
RC delay of clock signal.
Abstract: Trust and Energy consumption is the most challenging
issue in routing protocol design for Mobile ad hoc networks
(MANETs), since mobile nodes are battery powered and nodes
behaviour are unpredictable. Furthermore replacing and recharging
batteries and making nodes co-operative is often impossible in
critical environments like military applications. In this paper, we
propose a trust based energy aware routing model in MANET.
During route discovery, node with more trust and maximum energy
capacity is selected as a router based on a parameter called
'Reliability'. Route request from the source is accepted by a node
only if its reliability is high. Otherwise, the route request is
discarded. This approach forms a reliable route from source to
destination thus increasing network life time, improving energy
utilization and decreasing number of packet loss during transmission.
Abstract: In this paper, we propose a new architecture for the implementation of the N-point Fast Fourier Transform (FFT), based on the Radix-2 Decimation in Frequency algorithm. This architecture is based on a pipeline circuit that can process a stream of samples and produce two FFT transform samples every clock cycle. Compared to existing implementations the architecture proposed achieves double processing speed using the same circuit complexity.
Abstract: A model-free robust control (MFRC) approach is proposed for position control of robot manipulators in the state space. The control approach is verified analytically to be robust subject to uncertainties including external disturbances, unmodeled dynamics, and parametric uncertainties. There is a high flexibility to work on different systems including actuators by the use of the proposed control approach. The proposed control approach can guarantee the robustness of control system. A PUMA 560 robot driven by geared permanent magnet dc motors is simulated. The simulation results show a satisfactory performance for control system under technical specifications. KeywordsModel-free, robust control, position control, PUMA 560.
Abstract: GFRG(Glass Fiber Reinforced Gypsum) wall is a green product which can erect a building fast in prefabricated method, but its application to high-rise residential buildings is limited for its poor lateral stiffness. This paper has proposed a modification to GFRG walls structure to increase its lateral stiffness, which aiming to erect small high-rise residential buildings as load-bearing walls. The elastic finite element analysis to it has shown the lateral deformation feature and the distributions of the axial force and the shear force. The analysis results show that the new GFRG reinforced concrete wall can be used for small high-rise residential buildings.
Abstract: The iris recognition technology is the most accurate,
fast and less invasive one compared to other biometric techniques
using for example fingerprints, face, retina, hand geometry, voice or
signature patterns. The system developed in this study has the
potential to play a key role in areas of high-risk security and can
enable organizations with means allowing only to the authorized
personnel a fast and secure way to gain access to such areas. The
paper aim is to perform the iris region detection and iris inner and
outer boundaries localization. The system was implemented on
windows platform using Visual C# programming language. It is easy
and efficient tool for image processing to get great performance
accuracy. In particular, the system includes two main parts. The first
is to preprocess the iris images by using Canny edge detection
methods, segments the iris region from the rest of the image and
determine the location of the iris boundaries by applying Hough
transform. The proposed system tested on 756 iris images from 60
eyes of CASIA iris database images.
Abstract: A research study was conducted with an objective to propose a collaborative business strategy of a oil and gas trading company, representing PPT Energy Trading Co., Ltd., with its shareholder, especially electricity and power supply companies for LNG Form of Coal Bed Methane in B2B Transaction. Collaborative business strategy is a strategy to collaborate with other organizations due to have future benefits in both parties, or achieve the business objective through the collaboration of business, its strategy and partners. A structured interview was established to collect the required primary data from the company. Not only interview, but also company’s business plan and annual report were collected and analyzed for the company’s current condition. As the result, this research shows a recommendation to propose a new collaborative strategy with limiting its target market, diversifying product, conducting new business model, and considering other stakeholders.