Abstract: We have developed a new computer program in
Fortran 90, in order to obtain numerical solutions of a system
of Relativistic Magnetohydrodynamics partial differential equations
with predetermined gravitation (GRMHD), capable of simulating
the formation of relativistic jets from the accretion disk of matter
up to his ejection. Initially we carried out a study on numerical
methods of unidimensional Finite Volume, namely Lax-Friedrichs,
Lax-Wendroff, Nessyahu-Tadmor method and Godunov methods
dependent on Riemann problems, applied to equations Euler in
order to verify their main features and make comparisons among
those methods. It was then implemented the method of Finite
Volume Centered of Nessyahu-Tadmor, a numerical schemes that
has a formulation free and without dimensional separation of
Riemann problem solvers, even in two or more spatial dimensions,
at this point, already applied in equations GRMHD. Finally, the
Nessyahu-Tadmor method was possible to obtain stable numerical
solutions - without spurious oscillations or excessive dissipation -
from the magnetized accretion disk process in rotation with respect
to a central black hole (BH) Schwarzschild and immersed in a
magnetosphere, for the ejection of matter in the form of jet over a
distance of fourteen times the radius of the BH, a record in terms
of astrophysical simulation of this kind. Also in our simulations,
we managed to get substructures jets. A great advantage obtained
was that, with the our code, we got simulate GRMHD equations in
a simple personal computer.
Abstract: With a long history, dual-task has become one of the
most intriguing research fields regarding human brain functioning
and cognition. However, findings considering effects of taskinterrelations
are limited (especially, in combined motor and
cognitive tasks). Therefore, we aimed at developing a measurement
system in order to analyse interrelation effects of cognitive and motor
tasks. On the one hand, the present study demonstrates the
applicability of the measurement system and on the other hand first
results regarding a systematisation of different task combinations are
shown. Future investigations should combine imagine technologies
and this developed measurement system.
Abstract: In recent years, the compression of date (Phoenix
dactylifera L.) fruit powders (DP) to obtain date tablets (DT) has
been suggested as a promising form of valorization of non
commercial valuable date fruit (DF) varieties. To further improve
and characterize DT, the present study aims to investigate the
influence of the DP particle size and compression force on some
physical properties of DT. The results show that independently of
particle size, the hardness (y) of tablets increases with the increase of
the compression force (x) following a logarithmic law (y = a ln (bx)
where a and b are the constants of model). Further, a full factorial
design (FFD) at two levels, applied to investigate the erosion %,
reveals that the effects of time and particle size are the same in
absolute value and they are beyond the effect of the compression.
Regarding the disintegration time, the obtained results also by means
of a FFD show that the effect of the compression force exceeds 4
times that of the DP particle size. As final stage, the color parameters
in the CIELab system of DT immediately after their obtaining are
differently influenced by the size of the initial powder.
Abstract: Artificial Immune Systems (AIS), inspired by the
human immune system, are algorithms and mechanisms which are
self-adaptive and self-learning classifiers capable of recognizing and
classifying by learning, long-term memory and association. Unlike
other human system inspired techniques like genetic algorithms and
neural networks, AIS includes a range of algorithms modeling on
different immune mechanism of the body. In this paper, a mechanism
of a human immune system based on apoptosis is adopted to build an
Intrusion Detection System (IDS) to protect computer networks.
Features are selected from network traffic using Fisher Score. Based
on the selected features, the record/connection is classified as either
an attack or normal traffic by the proposed methodology. Simulation
results demonstrates that the proposed AIS based on apoptosis
performs better than existing AIS for intrusion detection.
Abstract: The presence of endocrine-disrupting compounds,
such as bisphenol A (BPA), in the environment can cause serious
health problems. However, there are controversial opinions. This
study investigated the reproductive, metabolic, oxidative and
immunologic-disrupting effects of bisphenol A in male rabbits.
Rabbits were divided into five groups. The first four rabbit groups
were administered oral BPA (1, 10, 50, or 100 mg/kg/day) for ten
weeks. The fifth group was administered corn oil as the vehicle. BPA
significantly decreased serum testosterone, estradiol and the free
androgen index (FAI) and significantly increased sex hormone
binding globulin (SHBG) compared with the placebo group. The
higher doses of BPA showed a significant decrease in follicular
stimulating hormone (FSH) and luteinizing hormone (LH). A
significant increase in blood glucose levels was identified in the BPA
groups. The non-significant difference in insulin levels is a novel
finding. The cumulative testicular toxicity of BPA was clearly
demonstrated by the dose-dependent decrease in absolute testes
weight, primary measures of semen quality and a significant increase
in testicular malonaldehyde (MDA). Moreover, BPA significantly
decreased total antioxidant capacity (TAC) and significantly
increased immunoglobulin G (IgG) at the highest concentration. Our
results suggest that BPA, especially at higher doses, is associated
with many adverse effects on metabolism, oxidative stress, immunity,
sperm quality and markers of androgenic action.
Abstract: Food contamination occurs during post process
handling. This leads to spoilage and growth of pathogenic
microorganisms in the food, thereby reducing its shelf life or
spreading of food borne diseases. Several methods are tried and one
of which is use of antimicrobial packaging. Here, papain, a protease
enzyme, is covalently immobilized with the help of glutarldehyde on
polyurethane and used as a food wrap to protect food from microbial
contamination. Covalent immobilization of papain was achieved at a
pH of 7.4; temperature of 4°C; glutaraldehyde concentration of 0.5%;
incubation time of 24h; and 50mg of papain. The formation of -C=Nobserved
in the Fourier transform infrared spectrum confirmed the
immobilization of the enzyme on the polymer. Immobilized enzyme
retained higher activity than the native free enzyme. The modified
polyurethane showed better reduction of Staphylococcus aureus
biofilm than bare polymer film (eight folds reduction in live colonies,
two times reduction in protein and 6 times reduction in
carbohydrates). The efficacy of this was studied by wrapping it over
S. aureus contaminated cottage cheese (paneer) and cheese and
stored at a temperature of 4°C for 7days. The modified film reduced
the bacterial contamination by eight folds when compared to the bare
film. FTIR also indicated reduction in lipids, sugars and proteins in
the biofilm.
Abstract: The liver is the strongest regenerating organ of the
organism, and even with 2/3 surgically removed, it can regenerate
completely. Hence liver cirrhosis may only develop when the
regenerating system is off.
We present the results of a comparative study of structural and
functional characteristics of rat liver tissue under the conditions of
toxic liver cirrhosis development, induced by carbon tetrachloride,
and its prevention/treatment by natural compounds with antioxidant
and immune stimulating action. Studies were made on Wister rats,
weighing 120~140 g. Grape seeds extracts, separately and in
combination with well-known anticirrhotic drug ursodeoxycholic
acid (Urdoxa), have demonstrated effectiveness in prevention of liver
cirrhosis development and its treatment.
Abstract: Electricity is recognized as fundamental to
industrialization and improving the quality of life of the people.
Harnessing the immense untapped hydropower potential in Tripura
region opens avenues for growth and provides an opportunity to
improve the well-being of the people of the region, while making
substantial contribution to the national economy. Gumti hydro power
plant generates power to mitigate the crisis of power in Tripura,
India. The first unit of hydro power plant (5MW) was commissioned
in June 1976 & another two units of 5 MW was commissioned
simultaneously. But out of 15MW capacity at present only 8MW-
9MW power is produced from Gumti hydro power plant during rainy
season. But during lean season the production reduces to 0.5MW due
to shortage of water. Now, it is essential to implement some
mitigation measures so that the further atrocities can be prevented
and originality will be possible to restore. The decision making
ability of the Analytic Hierarchy Process (AHP) and Concordance
Analysis Techniques (CAT) are utilized to identify the better decision
or solution to the present problem. Some related attributes are
identified by the method of surveying within the experts and the
available reports and literatures. Similar criteria are removed and
ultimately seven relevant ones are identified. All the attributes are
compared with each other and rated accordingly to their importance
over the other with the help of Pair wise Comparison Matrix. In the
present investigation different mitigation measures are identified and
compared to find the best suitable alternative which can solve the
present uncertainties involving the existence of the Gumti Hydro
Power Plant.
Abstract: In the second decade of the XXI century the role of
tourism destination attractiveness is becoming increasingly important
for destination management. Competition in tourism market moves
from ordinary service quality to provision of unforgettable emotional
experience for tourists. The main purpose of the present study is to
identify the perception of the tourism destinations based on the
number of factors related to its tourist attractiveness.
The content analysis method was used to analyze the on-line
tourist feedback data immensely available in Social Media and in
travel related sites. The collected data made it possible to procure the
information which is necessary to understand the perceived
attractiveness of the destinations and key destination appeal factors
that are important for Russian leisure travelers.
Results of the present study demonstrate key attractiveness factors
or destination ‘properties’ that were unveiled as the most important
for Russian leisure tourists. The study targeted five main Spanish
tourism destinations that initially were determined by in-depth
interview with a number of Russian nationals who had visited Spain
at least once.
The research results can be useful for Spanish Tourism
Organization Representation office in Russia as well as for the other
national tourism organizations in order to promote their respective
destinations for Russian travelers focusing on main attractiveness
factors identified in this study.
Abstract: One of the biggest challenges facing Theological/
Religious Education in Nigeria is access to quality learning materials.
For instance at the Trinity (Union) Theological College, Umuahia, it
was difficult for lecturers to access suitable and qualitative materials
for instruction especially the ones that would suit the African context
and stimulate a deep rooted interest among the students. Some
textbooks written by foreign authors were readily available in the
School Library, but were lacking in the College bookshops for
students to own copies. Even when the College was able to order
some of the books from abroad, it did not usher in the needed
enthusiasm expected from the students because they were either very
expensive or very difficult to understand during private studies. So it
became necessary to develop contextual materials which were
affordable and understandable, though with little success. The
National Open University of Nigeria (NOUN)’s innovation in the
development and sharing of learning resources through its Open
Courseware is a welcome development and of great assistance to
students. Apart from NOUN students who could easily access the
materials, many others from various theological/religious institutes
across the nation have benefited immensely. So, the thesis of this
paper is that the promotion of open educational resources in
theological/religious education in Nigeria would facilitate a better
informed/equipped religious leadership, which would in turn impact
its adherents for a healthier society and national development.
Adopting a narrative and historical approach within the context of
Nigeria’s educational system, the paper discusses: educational
traditions in Nigeria; challenges facing theological/religious
education in Nigeria; and benefits of open educational resources. The
study goes further to making recommendations on how OER could
positively influence theological/religious education in Nigeria. It is
expected that theologians, religious educators, and ODL practitioners
would find this work very useful.
Abstract: Since the emergence of e-Commerce, the world of
business has witnessed a radical shift in the way business activities
are conducted. However, the emergence of m-Commerce has further
pushed the boundaries of virtual commerce revolution. As a result,
there seems to be a growing blur in the distinction between e-
Commerce and m-Commerce. In addition, existing definitions for
both forms of commerce highlight characteristics (e.g. type of device
and activity conducted) that may be applicable to both concepts. The
aim of this paper is to identify the characteristics that help define and
delineate between e- and m- Commerce. The paper concludes that
characteristics of mobility, ubiquity and immediacy provide a clearer
and simpler template to distinguish between e-Commerce and m-
Commerce.
Abstract: Recent concerns about the value of teaching cursive
handwriting in the classroom are based on the belief that cursive
handwriting or penmanship is an outdated and unnecessary skill in
today’s online world. The discussion of this issue begins with a
description of current initiatives to eliminate handwriting instruction
in schools. This is followed by a brief history of cursive writing
through the ages. Next considered is a description of its benefits as a
preliminary process for younger children as compared with
immediate instruction in keyboarding, particularly in the areas of
vision, cognition, motor skills and automatic fluency. Also
considered, is cursive’s companion, paper itself, and the impact of a
paperless, “screen and keyboard” environment. The discussion
concludes with a consideration of the unique contributions of cursive
and keyboarding as written forms of communication, along with their
respective surfaces, paper and screen. Finally, an assessment of the
practical utility of each skill is followed by an informal assessment of
what is lost and what remains as we move from a predominantly
paper and pen world of handwriting to texting and keyboarding in an
environment of screens.
Abstract: Immunomodulators are substances that alter immune
system via dynamic regulation of messenger molecules. It can be
divided into immunostimulant and immunosuppressant. It can help to
increase immunity of people with a low immune system, and also can
help to normalize an overactive immune system. Aim of this study is
to investigate the effects of in vitro exposure to low and high doses of
several immunomodulators which include caffeine, kaloba and
quercetin on antigen-stimulated whole blood culture cytokine
production. Whole blood samples were taken from 5 healthy males
(age: 32 ± 12 years; weight: 75.7 ± 6.1 kg; BMI: 24.3 ± 1.5 kg/m2)
following an overnight fast with no vigorous activity during the
preceding 24 h. The whole blood was then stimulated with 50 μl of
100 x diluted Pediacel vaccine and low or high dose of
immunomodulators in the culture plate. After 20 h incubation (5%
CO2, 37°C), it was analysed using the Evidence Investigator to
determine the production of cytokines including IL-2, IL-4, IL-10,
IFN-γ, and IL-1α. Caffeine and quercetin showed a tendency towards
decrease cytokine production as the doses were increased. On the
other hand, an upward trend was evident with kaloba, where a high
dose of kaloba seemed to increase the cytokine production. In
conclusion, we found that caffeine and quercetin have potential as
immunosuppressant and kaloba as immunostimulant.
Abstract: This research is aimed to develop the online-class
scheduling management system and improve as a complex problem
solution, this must take into consideration in various conditions and
factors. In addition to the number of courses, the number of students
and a timetable to study, the physical characteristics of each class
room and regulations used in the class scheduling must also be taken
into consideration. This system is developed to assist management in
the class scheduling for convenience and efficiency. It can provide
several instructors to schedule simultaneously. Both lecturers and
students can check and publish a timetable and other documents
associated with the system online immediately. It is developed in a
web-based application. PHP is used as a developing tool. The
database management system was MySQL. The tool that is used for
efficiency testing of the system is questionnaire. The system was
evaluated by using a Black-Box testing. The sample was composed
of 2 groups: 5 experts and 100 general users. The average and the
standard deviation of results from the experts were 3.50 and 0.67.
The average and the standard deviation of results from the general
users were 3.54 and 0.54. In summary, the results from the research
indicated that the satisfaction of users were in a good level.
Therefore, this system could be implemented in an actual workplace
and satisfy the users’ requirement effectively.
Abstract: Pomegranate (Punica granatum L.) is an ancient fruit of great medical interest and rich source of antioxidants. Pesticides as dimethoate play a crucial role in the occurrence many diseases in plants, animal and human. Therefore the ability of Pomegranate (Punica granatum L.) to alleviate hepatotoxicity induced by organophosphate pesticide dimethoate was investigated. Albino male rats were divided randomly into 4 groups and kept at 7 animals per group in an environmentally controlled condition for 6 weeks. The first group was served as a control group (basal diet), the second group fed on basal diet supplemented with 5% freeze dried pomegranate seeds, the third group fed on 20 ppm dimethoate contaminated diet and the last group fed on dimethoate contaminated diet supplemented with 5% freeze dried pomegranate seeds. The results revealed that administration of dimethoate caused high significant increased in liver functions: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) activities as well as lipid peroxide (malonaldhyde, MDA); on the other hand high significant decreased on glutathione (GSH), glutathione peroxidase (GPx), albumin and total protein were observed. However addition of 5% freeze dried pomegranate seeds significantly improved all previously mentioned parameters. These results indicate the dimethoate induced hepatotoxicity and highlight the protective effect of pomegranate seeds as a potential protective agent against dimethoate induced hepatotoxicity. This may be attributed to the powerful antioxidants (polyphenols, total phenols, and total flavonoids) which present in high levels in pomegranate as well as improving the immunity by activation of antioxidant enzymes GSH and GPx.
Abstract: Multipotent mesenchymal stromal cells (MSCs)
possess immunomodulatory properties. The effect of MSCs on the
crucial cellular immunity compartment – T-cells is of a special
interest. It is known that MSC tissue niche and expected milieu of
their interaction with T- cells are characterized by low oxygen
concentration, whereas the in vitro experiments usually are carried
out at a much higher ambient oxygen (20%). We firstly evaluated
immunomodulatory effects of MSCs on T-cells at tissue-related
oxygen (5%) after interaction implied cell-to-cell contacts and
paracrine factors only. It turned out that MSCs under reduced oxygen
can effectively suppress the activation and proliferation of PHAstimulated
T-cells and can provoke decrease in the production of
proinflammatory and increase in anti-inflammatory cytokines. In
hypoxia some effects were amplified (inhibition of proliferation, antiinflammatory
cytokine profile shift). This impact was more evident
after direct cell-to-cell interaction; lack of intercellular contacts could
revoke the potentiating effect of hypoxia.
Abstract: Second line antiretroviral therapy (ART) regimen is
used when patients fail their first line regimen. There are many
factors such as non-adherence, drug resistance as well as virological
and immunological failure that lead to second line highly active
antiretroviral therapy (HAART) regimen treatment failure. This study
was aimed at determining predictor factors to treatment failure with
second line HAART and analyzing median survival time.
An observational, retrospective study was conducted in Sungai
Buloh Hospital (HSB) to assess current status of HIV patients treated
with second line HAART regimen. Convenience sampling was used
and 104 patients were included based on the study’s inclusion and
exclusion criteria. Data was collected for six months i.e. from July
until December 2013. Data was then analysed using SPSS version 18.
Kaplan-Meier and Cox regression analyses were used to measure
median survival times and predictor factors for treatment failure.
The study population consisted mainly of male subjects, aged 30-
45 years, who were heterosexual, and had HIV infection for less than
6 years. The most common second line HAART regimen given was
lopinavir/ritonavir (LPV/r)-based combination. Kaplan-Meier
analysis showed that patients on LPV/r demonstrated longer median
survival times than patients on indinavir/ritonavir (IDV/r) based
combination (p
Abstract: In the present work, detailed analysis on flow characteristics of a pair of immiscible liquids through horizontal pipeline is simulated by using ANSYS FLUENT 6.2. Moderately viscous oil and water (viscosity ratio = 107, density ratio = 0.89 and interfacial tension = 0.024 N/m) have been taken as system fluids for the study. Volume of Fluid (VOF) method has been employed by assuming unsteady flow, immiscible liquid pair, constant liquid properties, and co-axial flow. Meshing has been done using GAMBIT. Quadrilateral mesh type has been chosen to account for the surface tension effect more accurately. From the grid independent study, we have selected 47037 number of mesh elements for the entire geometry. Simulation successfully predicts slug, stratified wavy, stratified mixed and annular flow, except dispersion of oil in water, and dispersion of water in oil. Simulation results are validated with horizontal literature data and good conformity is observed. Subsequently, we have simulated the hydrodynamics (viz., velocity profile, area average pressure across a cross section and volume fraction profile along the radius) of stratified wavy and annular flow at different phase velocities. The simulation results show that in the annular flow, total pressure of the mixture decreases with increase in oil velocity due to the fact that pipe cross section is completely wetted with water. Simulated oil volume fraction shows maximum at the centre in core annular flow, whereas, in stratified flow, maximum value appears at upper side of the pipeline. These results are in accord with the actual flow configuration. Our findings could be useful in designing pipeline for transportation of crude oil.
Abstract: There is an essential need for obtaining the mathematical representation of fish body undulations, which can be used for designing and building new innovative types of marine propulsion systems with less environmental impact. This research work presents a case study to derive the mathematical model for fish body movement. Observation and capturing image methods were used in this study in order to obtain a mathematical representation of Clariasbatrachus fish (catfish). An experiment was conducted by using an aquarium with dimension 0.609 m x 0.304 m x 0.304 m, and a 0.5 m ruler was attached at the base of the aquarium. Progressive Scan Monochrome Camera was positioned at 1.8 m above the base of the aquarium to provide swimming sequences. Seven points were marked on the fish body using white marker to indicate the fish movement and measuring the amplitude of undulation. Images from video recordings (20 frames/s) were analyzed frame by frame using local coordinate system, with time interval 0.05 s. The amplitudes of undulations were obtained for image analysis from each point that has been marked on fish body. A graph of amplitude of undulations versus time was plotted by using computer to derive a mathematical fit. The function for the graph is polynomial with nine orders.
Abstract: As Malaysia aims to be a developed country by year 2020; the construction industry has since been identified as a major catalyst for the country to attain the status. It is one of the sectors that contribute to most environmental pollutions. It is, therefore, important for the industry to implement sustainable construction practices to reduce the negative impacts that it has on the environment. However, most Malaysian developers have placed much focus on market demand and economic factors; neglecting the need for attention on environmental issues. The practice of sustainable construction is deemed to be an obstacle to achieve short-term economic goals due to the higher cost incurred in the operations. Hence, choices need to be made and a balance needs to be struck in weighing the long-term environmental benefits against immediate economic factors. This paper discusses the challenges faced by Malaysian developers in adopting sustainable practices in the construction industry and the cause of these challenges. It also looks into the achievements and breakthroughs that developers in Malaysia have achieved so far. The paper aims explores the long-term benefits of sustainable practices that would potentially raise awareness on the feasibility and economic potential of sustainable construction.