An Agent-Based Approach to Immune Modelling: Priming Individual Response

This study focuses on examining why the range of experience with respect to HIV infection is so diverse, especially in regard to the latency period. An agent-based approach in modelling the infection is used to extract high-level behaviour which cannot be obtained analytically from the set of interaction rules at the cellular level. A prototype model encompasses local variation in baseline properties, contributing to the individual disease experience, and is included in a network which mimics the chain of lymph nodes. The model also accounts for stochastic events such as viral mutations. The size and complexity of the model require major computational effort and parallelisation methods are used.

PET/CT Patient Dosage Assay

A Positron Emission Tomography (PET) is a radioisotope imaging technique that illustrates the organs and the metabolisms of the human body. This technique is based on the simultaneous detection of 511 keV annihilation photons, annihilated as a result of electrons annihilating positrons that radiate from positron-emitting radioisotopes that enter biological active molecules in the body. This study was conducted on ten patients in an effort to conduct patient-related experimental studies. Dosage monitoring for the bladder, which was the organ that received the highest dose during PET applications, was conducted for 24 hours. Assessment based on measuring urination activities after injecting patients was also a part of this study. The MIRD method was used to conduct dosage calculations for results obtained from experimental studies. Results obtained experimentally and theoretically were assessed comparatively.

Digital filters for Hot-Mix Asphalt Complex Modulus Test Data Using Genetic Algorithm Strategies

The dynamic or complex modulus test is considered to be a mechanistically based laboratory test to reliably characterize the strength and load-resistance of Hot-Mix Asphalt (HMA) mixes used in the construction of roads. The most common observation is that the data collected from these tests are often noisy and somewhat non-sinusoidal. This hampers accurate analysis of the data to obtain engineering insight. The goal of the work presented in this paper is to develop and compare automated evolutionary computational techniques to filter test noise in the collection of data for the HMA complex modulus test. The results showed that the Covariance Matrix Adaptation-Evolutionary Strategy (CMA-ES) approach is computationally efficient for filtering data obtained from the HMA complex modulus test.

Policies that Enhance Learning and Teaching

Educational institutions often implement policies with the intention of influencing how learning and teaching occur. Generally, such policies are not as effective as their makers would like; changing the behavior of third-level teachers proves difficult. Nevertheless, a policy instituted in 2006 at the Dublin Institute of Technology has met with success: each newly hired faculty member must have a post-graduate qualification in “Learning and Teaching" or successfully complete one within the first two years of employment. The intention is to build teachers- knowledge about student-centered pedagogies and their capacity to implement them. As a result of this policy (and associated programs that support it), positive outcomes are readily apparent. Individual teachers who have completed the programs have implemented significant change at the course and program levels. This paper introduces the policy, identifies outcomes in relation to existing theory, describes research underway, and pinpoints areas where organizational learning has occurred.

Pruning Method of Belief Decision Trees

The belief decision tree (BDT) approach is a decision tree in an uncertain environment where the uncertainty is represented through the Transferable Belief Model (TBM), one interpretation of the belief function theory. The uncertainty can appear either in the actual class of training objects or attribute values of objects to classify. In this paper, we develop a post-pruning method of belief decision trees in order to reduce size and improve classification accuracy on unseen cases. The pruning of decision tree has a considerable intention in the areas of machine learning.

A Neurofuzzy Learning and its Application to Control System

A neurofuzzy approach for a given set of input-output training data is proposed in two phases. Firstly, the data set is partitioned automatically into a set of clusters. Then a fuzzy if-then rule is extracted from each cluster to form a fuzzy rule base. Secondly, a fuzzy neural network is constructed accordingly and parameters are tuned to increase the precision of the fuzzy rule base. This network is able to learn and optimize the rule base of a Sugeno like Fuzzy inference system using Hybrid learning algorithm, which combines gradient descent, and least mean square algorithm. This proposed neurofuzzy system has the advantage of determining the number of rules automatically and also reduce the number of rules, decrease computational time, learns faster and consumes less memory. The authors also investigate that how neurofuzzy techniques can be applied in the area of control theory to design a fuzzy controller for linear and nonlinear dynamic systems modelling from a set of input/output data. The simulation analysis on a wide range of processes, to identify nonlinear components on-linely in a control system and a benchmark problem involving the prediction of a chaotic time series is carried out. Furthermore, the well-known examples of linear and nonlinear systems are also simulated under the Matlab/Simulink environment. The above combination is also illustrated in modeling the relationship between automobile trips and demographic factors.

A New Perturbation Technique in Numerical Study on Buckling of Composite Shells under Axial Compression

A numerical study is presented on buckling and post buckling behaviour of laminated carbon fiber reinforced plastic (CFRP) thin-walled cylindrical shells under axial compression using asymmetric meshing technique (AMT). Asymmetric meshing technique is a perturbation technique to introduce disturbance without changing geometry, boundary conditions or loading conditions. Asymmetric meshing affects predicted buckling load, buckling mode shape and post-buckling behaviour. Linear (eigenvalue) and nonlinear (Riks) analyses have been performed to study the effect of asymmetric meshing in the form of a patch on buckling behaviour. The reduction in the buckling load using Asymmetric meshing technique was observed to be about 15%. An isolated dimple formed near the bifurcation point and the size of which increased to reach a stable state in the post-buckling region. The load-displacement curve behaviour applying asymmetric meshing is quite similar to the curve obtained using initial geometric imperfection in the shell model.

Screen of MicroRNA Targets in Zebrafish Using Heterogeneous Data Sources: A Case Study for Dre-miR-10 and Dre-miR-196

It has been established that microRNAs (miRNAs) play an important role in gene expression by post-transcriptional regulation of messengerRNAs (mRNAs). However, the precise relationships between microRNAs and their target genes in sense of numbers, types and biological relevance remain largely unclear. Dissecting the miRNA-target relationships will render more insights for miRNA targets identification and validation therefore promote the understanding of miRNA function. In miRBase, miRanda is the key algorithm used for target prediction for Zebrafish. This algorithm is high-throughput but brings lots of false positives (noise). Since validation of a large scale of targets through laboratory experiments is very time consuming, several computational methods for miRNA targets validation should be developed. In this paper, we present an integrative method to investigate several aspects of the relationships between miRNAs and their targets with the final purpose of extracting high confident targets from miRanda predicted targets pool. This is achieved by using the techniques ranging from statistical tests to clustering and association rules. Our research focuses on Zebrafish. It was found that validated targets do not necessarily associate with the highest sequence matching. Besides, for some miRNA families, the frequency of their predicted targets is significantly higher in the genomic region nearby their own physical location. Finally, in a case study of dre-miR-10 and dre-miR-196, it was found that the predicted target genes hoxd13a, hoxd11a, hoxd10a and hoxc4a of dre-miR- 10 while hoxa9a, hoxc8a and hoxa13a of dre-miR-196 have similar characteristics as validated target genes and therefore represent high confidence target candidates.

Coding based Synchronization Algorithm for Secondary Synchronization Channel in WCDMA

A new code synchronization algorithm is proposed in this paper for the secondary cell-search stage in wideband CDMA systems. Rather than using the Cyclically Permutable (CP) code in the Secondary Synchronization Channel (S-SCH) to simultaneously determine the frame boundary and scrambling code group, the new synchronization algorithm implements the same function with less system complexity and less Mean Acquisition Time (MAT). The Secondary Synchronization Code (SSC) is redesigned by splitting into two sub-sequences. We treat the information of scrambling code group as data bits and use simple time diversity BCH coding for further reliability. It avoids involved and time-costly Reed-Solomon (RS) code computations and comparisons. Analysis and simulation results show that the Synchronization Error Rate (SER) yielded by the new algorithm in Rayleigh fading channels is close to that of the conventional algorithm in the standard. This new synchronization algorithm reduces system complexities, shortens the average cell-search time and can be implemented in the slot-based cell-search pipeline. By taking antenna diversity and pipelining correlation processes, the new algorithm also shows its flexible application in multiple antenna systems.

One Hour Ahead Load Forecasting Using Artificial Neural Network for the Western Area of Saudi Arabia

Load forecasting has become in recent years one of the major areas of research in electrical engineering. Most traditional forecasting models and artificial intelligence neural network techniques have been tried out in this task. Artificial neural networks (ANN) have lately received much attention, and a great number of papers have reported successful experiments and practical tests. This article presents the development of an ANN-based short-term load forecasting model with improved generalization technique for the Regional Power Control Center of Saudi Electricity Company, Western Operation Area (SEC-WOA). The proposed ANN is trained with weather-related data and historical electric load-related data using the data from the calendar years 2001, 2002, 2003, and 2004 for training. The model tested for one week at five different seasons, typically, winter, spring, summer, Ramadan and fall seasons, and the mean absolute average error for one hour-ahead load forecasting found 1.12%.

A Fast Adaptive Content-based Retrieval System of Satellite Images Database using Relevance Feedback

In this paper, we present a system for content-based retrieval of large database of classified satellite images, based on user's relevance feedback (RF).Through our proposed system, we divide each satellite image scene into small subimages, which stored in the database. The modified radial basis functions neural network has important role in clustering the subimages of database according to the Euclidean distance between the query feature vector and the other subimages feature vectors. The advantage of using RF technique in such queries is demonstrated by analyzing the database retrieval results.

The First Ground Track Maintenance Manoeuvre of THEOS Spacecraft

THEOS is the first earth observation spacecraft of Thailand which was launched on the 1st October 2008 and is currently operated by GISTDA. The transfer phase has been performed by Astrium Flight Dynamics team leading to a hand over to GISTDA teams starting mid-October 2008. The THEOS spacecraft-s orbit is LEO and has the same repetitivity (14+5/26) as the SPOT spacecraft, i.e. the same altitude of 822 km but it has a different mean local solar time (LST). Ground track maintenance manoeuvres are performed to maintain the ground track within a predefined control band around the reference ground track and the band is ±40 km for THEOS spacecraft. This paper presents the first ground track maintenance manoeuvre of THEOS spacecraft and the detailed results. In addition, it also includes one and a half year of operation as seen by GISTDA operators. It finally describes the foreseenable activities for the next orbit control manoeuvre (OCM) preparation.

The Causation and Solution of Ringing Effect in DCT-based Video Coding

Ringing effect is one of the most annoying visual artifacts in digital video. It is a significant factor of subjective quality deterioration. However, there is a widely-accepted misunderstanding of its cause. In this paper, we propose a reasonable interpretation of the cause of ringing effect. Based on the interpretation, we suggest further two methods to reduce ringing effect in DCT-based video coding. The methods adaptively adjust quantizers according to video features. Our experiments proved that the methods could efficiently improve subjective quality with acceptable additional computing costs.

Application of Build-up and Wash-off Models for an East-Australian Catchment

Estimation of stormwater pollutants is a pre-requisite for the protection and improvement of the aquatic environment and for appropriate management options. The usual practice for the stormwater quality prediction is performed through water quality modeling. However, the accuracy of the prediction by the models depends on the proper estimation of model parameters. This paper presents the estimation of model parameters for a catchment water quality model developed for the continuous simulation of stormwater pollutants from a catchment to the catchment outlet. The model is capable of simulating the accumulation and transportation of the stormwater pollutants; suspended solids (SS), total nitrogen (TN) and total phosphorus (TP) from a particular catchment. Rainfall and water quality data were collected for the Hotham Creek Catchment (HTCC), Gold Coast, Australia. Runoff calculations from the developed model were compared with the calculated discharges from the widely used hydrological models, WBNM and DRAINS. Based on the measured water quality data, model water quality parameters were calibrated for the above-mentioned catchment. The calibrated parameters are expected to be helpful for the best management practices (BMPs) of the region. Sensitivity analyses of the estimated parameters were performed to assess the impacts of the model parameters on overall model estimations of runoff water quality.

Security Architecture for At-Home Medical Care Using Sensor Network

This paper proposes a novel architecture for At- Home medical care which enables senior citizens, patients with chronic ailments and patients requiring post- operative care to be remotely monitored in the comfort of their homes. This architecture is implemented using sensors and wireless networking for transmitting patient data to the hospitals, health- care centers for monitoring by medical professionals. Patients are equipped with sensors to measure their physiological parameters, like blood pressure, pulse rate etc. and a Wearable Data Acquisition Unit is used to transmit the patient sensor data. Medical professionals can be alerted to any abnormal variations in these values for diagnosis and suitable treatment. Security threats and challenges inherent to wireless communication and sensor network have been discussed and a security mechanism to ensure data confidentiality and source authentication has been proposed. Symmetric key algorithm AES has been used for encrypting the data and a patent-free, two-pass block cipher mode CCFB has been used for implementing semantic security.

The Relationship between Learners-Motivation (Integrative and Instrumental) and English Proficiency among Iranian EFL Learners

The current study aims at investigating the relationship between the learners- integrative and instrumental motivation and English proficiency among Iranian EFL learners. The participants in this study consisted of 128 undergraduate university students including 64 males and 64 females, majoring in English as a foreign language, from Shiraz Azad University. Two research instruments were used to gather the needed data for this study: 1) Language Proficiency Test. 2) A scale on motivation which determines the type of the EFL learners- motivation. Correlatin coefficient and t-test were used to analyze the collected data and the main result was found as follows: There is a significant relationship between the integrative motivation and instrumental motivation with English proficiency among EFL learners of Shiraz Azad University.

A Global Condition for the Triviality of an Almost Split Quaternionic Structure on Split Complex Manifolds

Let M be an almost split quaternionic manifold on which its almost split quaternionic structure is defined by a three dimensional subbundle V of ( T M) T (M) * Ôèù and {F,G,H} be a local basis for V . Suppose that the (global) (1, 2) tensor field defined[V ,V ]is defined by [V,V ] = [F,F]+[G,G] + [H,H], where [,] denotes the Nijenhuis bracket. In ref. [7], for the almost split-hypercomplex structureH = J α,α =1,2,3, and the Obata connection ÔêçH vanishes if and only if H is split-hypercomplex. In this study, we give a prof, in particular, prove that if either M is a split quaternionic Kaehler manifold, or if M is a splitcomplex manifold with almost split-complex structure F , then the vanishing [V ,V ] is equivalent to that of all the Nijenhuis brackets of {F,G,H}. It follows that the bundle V is trivial if and only if [V ,V ] = 0 .

Investigation of Phytoextraction Coefficient Different Combination of Heavy Metals in Barley and Alfalfa

Two seperate experiments by barley and alfalfa were conducted to a 2×8 factorial completely randomised design, with four replicates. Factors were inoculation (M) with Gomus mosseae or uninoculation (M0) and seven levels of contaminants (Co, Cd, Pb and combinations) plus an uncontaminated control treatment (C). Heavy metals in plant tissues and soil were quantified by Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES) (Variant- Liberty 150AX Turbo). Phytoextraction coefficient of contaminants calculated by concentration of heavy metals in the shoot (mgkg-1) / concentration of heavy metals in soil (mgkg-1). In the barley, the highest rate of phytoextraction coefficient of Pb, Cd and Co was in M0Pb, M0PbCoCd and MCo, respectively (P

Behavior of Media Exposure and Participation in Environmental Activities of King Mongkut-s University of Technology Thonburi Dormitory Students

The purposes of this research were 1) to investigate behavior of media exposure and participation in environmental activities of King Mongkut-s University of Technology Thonburi (KMUTT) dormitory students, 2) to compare the correlation between faculties and participation in environmental activities of KMUTT dormitory students, and 3) to compare the correlation between media exposure and participation in environmental activities of KMUTT dormitory students. The tool used for collecting data was questionnaire. The research findings revealed that dormitory students were mostly exposed to the environmental media via public relations boards for general media and KMUTT dormitory media. Dormitory students were daily exposed to media via websites on the internet and weekly for other media. Dormitory students participation in the environmental activities was at high level (x = 3.65) on an individual basis and was at medium level (x = 2.76) on a collective basis. Faculties did not correlate with the participation in environmental activities of dormitory students at the .01 statistical level and media exposure via various media correlated with participation in environmental activities of dormitory students at the .01 statistical level.

Experimental Study of the Extraction of Copper(II) from Sulphuric Acid by Means of Sodium Diethyldithiocarbamate (SDDT)

The present work presents the extraction of copper(II) from sulphuric acid solutions with Sodium diethyldithiocarbamate (SDDT), and six different organic diluents: Dichloromethane, Chloroform, Carbon tetrachloride, Toluene, xylene and Cyclohexane, were tested. The pair SDDT/Chloroform showed to be the most selective in removing the copper cations, and hence was considered throughout the experimental study. The effects of operating parameters such as the initial concentration of the extracting agent, the agitation time, the agitation speed and the acid concentration were considered. For an initial concentration of Cu (II) of 63 ppm in a 0.5 M sulphuric acid solution, both with a mass of the extracting agent of 20 mg, an extraction percentage of about 97.8 % and a distribution coefficient of 44.42 were obtained, respectively, confirming the performance of the SDDT-Chloroform pair.