Abstract: Cancer is still one of the serious diseases threatening
the lives of human beings. How to have an early diagnosis and
effective treatment for tumors is a very important issue. The animal
carcinoma model can provide a simulation tool for the studies of
pathogenesis, biological characteristics, and therapeutic effects.
Recently, drug delivery systems have been rapidly developed to
effectively improve the therapeutic effects. Liposome plays an
increasingly important role in clinical diagnosis and therapy for
delivering a pharmaceutic or contrast agent to the targeted sites.
Liposome can be absorbed and excreted by the human body, and is
well known that no harm to the human body. This study aimed to
compare the therapeutic effects between encapsulated (doxorubicin
liposomal, Lipodox) and un-encapsulated (doxorubicin, Dox)
anti-tumor drugs using magnetic resonance imaging (MRI).
Twenty-four New Zealand rabbits implanted with VX2 carcinoma at
left thighs were classified into three groups: control group (untreated),
Dox-treated group, and LipoDox-treated group, 8 rabbits for each
group. MRI scans were performed three days after tumor implantation.
A 1.5T GE Signa HDxt whole body MRI scanner with a high
resolution knee coil was used in this study. After a 3-plane localizer
scan was performed, three-dimensional (3D) fast spin echo (FSE)
T2-weighted Images (T2WI) was used for tumor volumetric
quantification. Afterwards, two-dimensional (2D) spoiled gradient
recalled echo (SPGR) dynamic contrast-enhanced (DCE) MRI was
used for tumor perfusion evaluation. DCE-MRI was designed to
acquire four baseline images, followed by contrast agent Gd-DOTA
injection through the ear vein of rabbit. A series of 32 images were
acquired to observe the signals change over time in the tumor and
muscle. The MRI scanning was scheduled on a weekly basis for a
period of four weeks to observe the tumor progression longitudinally.
The Dox and LipoDox treatments were prescribed 3 times in the first
week immediately after the first MRI scan; i.e. 3 days after VX2 tumor
implantation. ImageJ was used to quantitate tumor volume and time
course signal enhancement on DCE images. The changes of tumor size
showed that the growth of VX2 tumors was effectively inhibited for
both LipoDox-treated and Dox-treated groups. Furthermore, the tumor
volume of LipoDox-treated group was significantly lower than that of
Dox-treated group, which implies that LipoDox has better therapeutic effect than Dox. The signal intensity of LipoDox-treated group is
significantly lower than that of the other two groups, which implies
that targeted therapeutic drug remained in the tumor tissue. This study
provides a radiation-free and non-invasive MRI method for
therapeutic monitoring of targeted liposome on an animal tumor
model.
Abstract: The aim of this study is to empirically investigate the
mediating impact of export performance (EP) between technological
advancement capabilities and business performance (BP) of
Malaysian manufacturing micro, small and medium sized enterprises
(MSME’s). Firm’s technological advancement resources are
hypothesized as a platform to enhance both exports and BP of
manufacturing MSMEs in Malaysia. This study is twofold, primary it
has investigated that technological advancement capabilities helps to
appreciates main performance measures noted in terms of EP and
Secondly, it investigates that how efficiently and effectively
technological advancement capabilities can contribute in overall
Malaysian MSME’s BP. Smart PLS-3 statistical software is used to
know the association between technological advancement
capabilities, MSME’s EP and BP. In this study, the data was
composed from Malaysian manufacturing MSME’s in east coast
industrial zones known as the manufacturing hub of MSMEs. Seven
hundred and fifty (750) questionnaires were distributed, but only 148
usable questionnaires are returned. The finding of this study indicated
that technological advancement capabilities helps to strengthen the
export in term of time and cost efficient and it plays a significant role
in appreciating their BP. This study is helpful for small and medium
enterprise owners who intend to expand their business overseas and
though smart technological advancement resources they can achieve
their business competitiveness and excellence both at local and
international markets.
Abstract: Obturator Foramen is a specific structure in Pelvic
bone images and recognition of it is a new concept in medical image
processing. Moreover, segmentation of bone structures such as
Obturator Foramen plays an essential role for clinical research in
orthopedics. In this paper, we present a novel method to analyze the
similarity between the substructures of the imaged region and a hand
drawn template as a preprocessing step for computation of Pelvic
bone rotation on hip radiographs. This method consists of integrated
usage of Marker-controlled Watershed segmentation and Zernike
moment feature descriptor and it is used to detect Obturator Foramen
accurately. Marker-controlled Watershed segmentation is applied to
separate Obturator Foramen from the background effectively. Then,
Zernike moment feature descriptor is used to provide matching
between binary template image and the segmented binary image for
final extraction of Obturator Foramens. Finally, Pelvic bone rotation
rate calculation for each hip radiograph is performed automatically to
select and eliminate hip radiographs for further studies which depend
on Pelvic bone angle measurements. The proposed method is tested
on randomly selected 100 hip radiographs. The experimental results
demonstrated that the proposed method is able to segment Obturator
Foramen with 96% accuracy.
Abstract: Detecting changes in multiple images of the same
scene has recently seen increased interest due to the many
contemporary applications including smart security systems, smart
homes, remote sensing, surveillance, medical diagnosis, weather
forecasting, speed and distance measurement, post-disaster forensics
and much more. These applications differ in the scale, nature, and
speed of change. This paper presents an application of image
processing techniques to implement a real-time change detection
system. Change is identified by comparing the RGB representation of
two consecutive frames captured in real-time. The detection threshold
can be controlled to account for various luminance levels. The
comparison result is passed through a filter before decision making to
reduce false positives, especially at lower luminance conditions. The
system is implemented with a MATLAB Graphical User interface
with several controls to manage its operation and performance.
Abstract: The aim of this paper is to analyze the impact of
literature review software on researchers. The aim of this study was
achieved by analyzing models in terms of perceived usefulness,
perceived ease of use, and acceptance level. Collected data were
analyzed using WarpPLS 4.0 software. This study used two
theoretical frameworks, namely, Technology Acceptance Model and
the Training Needs Assessment Model. The study was experimental
and was conducted at a public university in South Africa. The results
of the study showed that acceptance level has a high impact on
research productivity followed by perceived usefulness and perceived
ease of use.
Abstract: Cost overruns are a persistent problem in oil and gas
megaprojects. Whilst the extant literature is filled with studies on
incidents and causes of cost overruns, underlying theories to explain
their emergence in oil and gas megaprojects are few. Yet, a way to
contain the syndrome of cost overruns is to understand the bases of
‘how and why’ they occur. Such knowledge will also help to develop
pragmatic techniques for better overall management of oil and gas
megaprojects. The aim of this paper is to explain the development of
cost overruns in hydrocarbon megaprojects through the perspective of
chaos theory. The underlying principles of chaos theory and its
implications for cost overruns are examined and practical
recommendations proposed. In addition, directions for future research
in this fertile area provided.
Abstract: This paper presents a comparative analysis of
continuously stirred tank reactor (CSTR) control based on adaptive
control and optimal tuning of PID control based on particle swarm
optimization. In the design of adaptive control, Model reference
adaptive control (MRAC) scheme is used, in which the adaptation
law have been developed by MIT rule & Lyapunov’s rule. In PSO
control parameters of PID controller is tuned by using the concept of
particle swarm optimization to get optimized operating point for
minimum integral square error (ISE) condition. The results show the
adjustment of PID parameters converting into the optimal operating
point and the good control response can be obtained by the PSO
technique.
Abstract: One of the challenges that higher education faces is to
find how to approach the sustainability in an inclusive way to the
student within all the different academic areas, how to move the
sustainable development from the abstract field to the operational
field. This research comes from the ecoliteracy and the pedagogical
praxis as tools for rebuilding the teaching processes inside of
universities. The purpose is to determine and describe which are the
factors involved in the process of learning particularly in the
Greenhouse-School Siembra UV. In the Greenhouse-School Siembra UV, of the University of
Veracruz, are cultivated vegetables, medicinal plants and small
cornfields under the usage of eco-technologies such as hydroponics,
Wickingbed and Hugelkultur, which main purpose is the saving of
space, labor and natural resources, as well as function as agricultural
production alternatives in the urban and periurban zones. The sample was formed with students from different academic
areas and who are actively involved in the greenhouse, as well as
institutes from the University of Veracruz and governmental and nongovernmental
departments. This project comes from a pedagogic praxis approach, from filling
the needs that the different professional profiles of the university
students have. All this with the purpose of generate a pragmatic
dialogue with the sustainability. It also comes from the necessity to
understand the factors that intervene in the students’ praxis. In this
manner is how the students are the fundamental unit in the sphere of
sustainability. As a result, it is observed that those University of Veracruz
students who are involved in the Greenhouse-school, Siembra UV,
have enriched in different levels the sense of urban and periurban
agriculture because of the diverse academic approaches they have
and the interaction between them. It is concluded that the ecotechnologies
act as fundamental tools for ecoliteracy in society,
where it is strengthen the nutritional and food security from a
sustainable development approach.
Abstract: Background: To compare the thinning patterns of the
ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal
nerve fiber layer (pRNFL) as measured using Cirrus high-definition
optical coherence tomography (HD-OCT) in patients with visual field
(VF) defects that respect the vertical meridian. Methods: Twenty eyes of eleven patients with VF defects that
respect the vertical meridian were enrolled retrospectively. The
thicknesses of the macular GCIPL and pRNFL were measured using
Cirrus HD-OCT. The 5% and 1% thinning area index (TAI) was
calculated as the proportion of abnormally thin sectors at the 5% and
1% probability level within the area corresponding to the affected VF.
The 5% and 1% TAI were compared between the GCIPL and pRNFL
measurements. Results: The color-coded GCIPL deviation map showed a
characteristic vertical thinning pattern of the GCIPL, which is also
seen in the VF of patients with brain lesions. The 5% and 1% TAI
were significantly higher in the GCIPL measurements than in the
pRNFL measurements (all P < 0.01). Conclusions: Macular GCIPL analysis clearly visualized a
characteristic topographic pattern of retinal ganglion cell (RGC) loss
in patients with VF defects that respect the vertical meridian, unlike
pRNFL measurements. Macular GCIPL measurements provide more
valuable information than pRNFL measurements for detecting the
loss of RGCs in patients with retrograde degeneration of the optic
nerve fibers.
Abstract: At the present work, highly transparent strip type
quasi-solid state dye-sensitized solar cells (DSSCs) were fabricated
through inkjet printing using nanocomposite TiO2 inks as raw
materials and tested under outdoor illumination conditions. The cells,
which can be considered as the structural units of large area modules,
were fully characterized electrically and electrochemically and after
the evaluation of the received results a large area DSSC module was
manufactured. The module design was a sandwich Z-interconnection
where the working electrode is deposited on one conductive glass and
the counter electrode on a second glass. Silver current collective
fingers were printed on the conductive glasses to make the internal
electrical connections and the adjacent cells were connected in series
and finally insulated using a UV curing resin to protect them from the
corrosive (I-/I3-) redox couple of the electrolyte. Finally, outdoor tests
were carried out to the fabricated dye-sensitized solar module and its
performance data were collected and assessed.
Abstract: Adoption of Information Systems (IS) is receiving
increasing attention such that its implications have been closely
monitored and studied by the IS management community, industry
and professional gatekeepers. Building on previous research
regarding the adoption of technology, this paper develops and
validates an integrated model of the adoption of mobile banking. The
model originates from the Technology Acceptance Model (TAM) and
the Theory of Planned Behaviour (TPB). This paper intends to offer a
preliminary scrutiny of the antecedents of the adoption of mobile
banking services in the context of a developing country. Data was
collected from Pakistan. The findings showed that an integrated TAM
and TPB model greatly explains the adoption intention of mobile
banking; and perceived behavioural control and its antecedents play a
significant role in predicting adoption Theoretical and managerial
implications of findings are presented and discussed.
Abstract: An unrecorded experiment of use of the smartphone
as a tool for practical classes of histology is presented in this paper.
Behavior and learning of students of science courses at the University
were analyzed and compared as well as the mode of teaching of this
discipline and the appreciation of the students, using either digital
photographs taken by phone or drawings for record microscopic
observations, analyze and interpret histological sections of human or
animal tissues.
Abstract: The relationship dependence between RSS and distance
in an enclosed environment is an important consideration because it is
a factor that can influence the reliability of any localization algorithm
founded on RSS. Several algorithms effectively reduce the variance of
RSS to improve localization or accuracy performance. Our proposed
algorithm essentially avoids this pitfall and consequently, its high
adaptability in the face of erratic radio signal. Using 3 anchors in
close proximity of each other, we are able to establish that RSS can be
used as reliable indicator for localization with an acceptable degree of
accuracy. Inherent in this concept, is the ability for each prospective
anchor to validate (guarantee) the position or the proximity of the
other 2 anchors involved in the localization and vice versa. This
procedure ensures that the uncertainties of radio signals due to
multipath effects in enclosed environments are minimized. A major
driver of this idea is the implicit topological relationship among
sensors due to raw radio signal strength. The algorithm is an area
based algorithm; however, it does not trade accuracy for precision
(i.e the size of the returned area).
Abstract: Cryosorption pumps are considered safe, quiet, and
ultra-high vacuum production pumps which have their application
from Semiconductor industries to ITER [International Thermonuclear
Experimental Reactor] units. The principle of physisorption of gases
over highly porous materials like activated charcoal at cryogenic
temperatures (below -1500°C) is involved in determining the
pumping speed of gases like Helium, Hydrogen, Argon, and
Nitrogen. This paper aims at providing detailed overview of
development of Cryosorption pump and characterization of different
activated charcoal materials that optimizes the performance of the
pump. Different grades of charcoal were tested in order to determine
the pumping speed of the pump and were compared with
commercially available Varian cryopanel. The results for bare panel,
bare panel with adhesive, cryopanel with pellets, and cryopanel with
granules were obtained and compared. The comparison showed that
cryopanel adhered with small granules gave better pumping speeds
than large sized pellets.
Abstract: In this paper, we present an application of Riemannian
geometry for processing non-Euclidean image data. We consider the
image as residing in a Riemannian manifold, for developing a new
method to brain edge detection and brain extraction. Automating this
process is a challenge due to the high diversity in appearance brain
tissue, among different patients and sequences. The main contribution, in this paper, is the use of an edge-based
anisotropic diffusion tensor for the segmentation task by integrating
both image edge geometry and Riemannian manifold (geodesic,
metric tensor) to regularize the convergence contour and extract
complex anatomical structures. We check the accuracy of the
segmentation results on simulated brain MRI scans of single
T1-weighted, T2-weighted and Proton Density sequences. We
validate our approach using two different databases: BrainWeb
database, and MRI Multiple sclerosis Database (MRI MS DB). We
have compared, qualitatively and quantitatively, our approach with
the well-known brain extraction algorithms. We show that using
a Riemannian manifolds to medical image analysis improves the
efficient results to brain extraction, in real time, outperforming the
results of the standard techniques.
Abstract: Maintaining factory default battery endurance rate
over time in supporting huge amount of running applications on
energy-restricted mobile devices has created a new challenge for
mobile applications developer. While delivering customers’
unlimited expectations, developers are barely aware of efficient use
of energy from the application itself. Thus, developers need a set of
valid energy consumption indicators in assisting them to develop
energy saving applications. In this paper, we present a few software
product metrics that can be used as an indicator to measure energy
consumption of Android-based mobile applications in the early of
design stage. In particular, Trepn Profiler (Power profiling tool for
Qualcomm processor) has used to collect the data of mobile
application power consumption, and then analyzed for the 23
software metrics in this preliminary study. The results show that
McCabe cyclomatic complexity, number of parameters, nested block
depth, number of methods, weighted methods per class, number of
classes, total lines of code and method lines have direct relationship
with power consumption of mobile application.
Abstract: The article deals with the readiness of military
professionals for challenging situations. It discusses higher
requirements on the psychical endurance of military professionals
arising from the specific nature of the military occupation, which is
typical for being very difficult to maintain regularity, which is in
accordance with the hygiene of work alternated by relaxation. The
soldier must be able to serve in the long term and constantly intense
performance that goes beyond human tolerance to stress situations. A
challenging situation is always associated with overcoming
difficulties, obstacles and complicated circumstances or using
unusual methods, ways and means to achieve the desired (expected)
objectives, performing a given task or satisfying an important need.
This paper describes the categories of challenging situations, their
classification and characteristics. Attention is also paid to the
formation of personality in challenging situations, coping with stress
in challenging situations, Phases of solutions of stressful situations,
resistance to challenging life situations and its factors. Finally, the
article is focused on increasing the readiness of military professionals
for challenging situations.
Abstract: The paper shows that on transferring sense from the
SL to the TL, the translator’s reading against the grain determines the
creation of a faulty pattern of rendering the original meaning in the
receiving culture which reflects the use of misleading transformative
codes. In this case, the translator is a writer per se who decides what
goes in and out of the book, how the style is to be ciphered and what
elements of ideology are to be highlighted. The paper also proves that
figurative language must not be flattened for the sake of clarity or
naturalness. The missing figurative elements make the translated text
less interesting, less challenging and less vivid which reflects poorly
on the writer. There is a close connection between style and the
writer’s person. If the writer’s style is very much altered in a
translation, the translation is useless as the original writer and his /
her imaginative world can no longer be discovered. The purpose of the paper is to prove that adaptation is a dangerous
tool which leads to variants that sometimes reflect the original less
than the reader would wish to. It contradicts the very essence of the
process of translation which is that of making an original work
available in a foreign language. If the adaptive transformative codes
are so flexible that they encourage the translator to repeatedly leave
out parts of the original work, then a subversive pattern emerges
which changes the entire book. In conclusion, as a result of using adaptation, manipulative or
subversive effects are created in the translated work. This is generally
achieved by adding new words or connotations, creating new figures
of speech or using explicitations. The additional meanings of the
original work are neglected and the translator creates new meanings,
implications, emphases and contexts. Again s/he turns into a new
author who enjoys the freedom of expressing his / her own ideas
without the constraints of the original text. Reading against the grain
is unadvisable during the process of translation and consequently,
following personal common sense becomes essential in the field of
translation as well as everywhere else, so that translation should not
become a source of fantasy.
Abstract: The growth in the demand of electrical energy is
leading to load on the Power system which increases the occurrence
of frequent oscillations in the system. The reason for the oscillations
is due to the lack of damping torque which is required to dominate
the disturbances of Power system. By using FACT devices, such as
Unified Power Flow Controller (UPFC) can control power flow,
reduce sub-synchronous resonances and increase transient stability.
Hence, UPFC is used to damp the oscillations occurred in Power
system. This research focuses on adapting the neuro fuzzy controller
for the UPFC design by connecting the infinite bus (SMIB - Single
machine Infinite Bus) to a linearized model of synchronous machine
(Heffron-Phillips) in the power system. This model gains the
capability to improve the transient stability and to damp the
oscillations of the system.
Abstract: Abstract—[Tris (1,10-phenanthroline) lanthanum(III)]
trithiocyanate is a new compound that has shown high ability for
stopping the synthesis of DNA and also acting as a photosensitizer.
Nowadays, the radiation dose assessment resource (RADAR) method
is known as the most common method for absorbed dose calculation.
177Lu was produced by (n, gamma) reaction in a research reactor.
177Lu-PL3 was prepared in the optimized condition. The
radiochemical yield was checked by ITLC method. The
biodistribution of the complex was investigated by intravenously
injection to wild-type rats via their tail veins. In this study, the
absorbed dose of 177Lu-PL3 to human organs was estimated by
RADAR method. 177Lu was prepared with a specific activity of 2.6-3
GBq.mg-1 and radionuclide purity of 99.98 %. Final preparation of
the radiolabelled complex showed high radiochemical purity of >
99%. The results show that liver and spleen have received the highest
absorbed dose of 1.051 and 0.441 mSv/MBq, respectively. The
absorbed dose values for these two dose-limiting tissues suggest
more biological studies special in tumor-bearing animals.