Abstract: The aim of the present study was to evaluate the
mucoadhesion and the release of nicotinamide gel formulations using
in vitro methods. An agar plate technique was used to investigate the
adhesiveness of the gels whereas a diffusion apparatus was employed
to determine the release of nicotinamide from the gels. In this
respect, 10% w/w nicotinamide gels containing bioadhesive
polymers: Carbopol 934P (0.5-2% w/w), hydroxypropylmethyl
cellulose (HPMC) (4-10% w/w), sodium carboxymethyl cellulose
(SCMC) (4-6% w/w) and methylcellulose 4000 (MC) (3-5% w/w)
were prepared. The gel formulations had pH values in the range of
7.14 - 8.17, which were considered appropriate to oral mucosa
application. In general, the rank order of pH values appeared to be
SCMC > MC4000 > HPMC > Carbopol 934P. Types and
concentrations of polymers used somewhat affected the
adhesiveness. It was found that anionic polymers (Carbopol 934 and
SCMC) adhered more firmly to the agar plate than the neutral
polymers (HPMC and MC 4000). The formulation containing 0.5%
Carbopol 934P (F1) showed the highest release rate. With the
exception of the formulation F1, the neutral polymers tended to give
higher relate rates than the anionic polymers. For oral tissue
treatment, the optimum has to be balanced between the residence
time (adhesiveness) of the formulations and the release rate of the
drug. The formulations containing the anionic polymers: Carbopol
934P or SCMC possessed suitable physical properties (appearance,
pH and viscosity). In addition, for anionic polymer formulations,
justifiable mucoadhesive properties and reasonable release rates of
nicotinamide were achieved. Accordingly, these gel formulations
may be applied for the treatment of oral mucosal lesions.
Abstract: Palm oil could be converted to cocoa butter equivalent by lipase-catalyzed interesterification. The objective of this research was to investigate the structure modification of palm oil to cocoa butter equivalent using Carica papaya lipase –catalyzed interesterification. The study showed that the compositions of cocoa butter equivalent were affected by acyl donor sources, substrate ratio, initial water of enzyme, reaction time, reaction temperature and the amount of enzyme. Among three acyl donors tested (methyl stearate, ethyl stearate and stearic acid), methyl stearate appeared to be the best acyl donor for incorporation to palm oil structure. The best reaction conditions for cocoa butter equivalent production were : substrate ratio (palm oil : methyl stearate, mol/mol) at 1 : 4, water activity of enzyme at 0.11, reaction time at 4 h, reaction temperature at 45 ° C and 18% by weight of the enzyme. The chemical and physical properties of cocoa butter equivalent were 9.75 ± 0.41% free fatty acid, 44.89 ± 0.84 iodine number, 193.19 ± 0.78 sponification value and melting point at 37-39 °C.
Abstract: An ethical mandate of the social work profession in the
United States is that BSW and MSW graduates are sufficiently
prepared to both understand diverse cultural values and beliefs and
offer services that are culturally sensitive and relevant to clients. This
skill set is particularly important for social workers in the 21st Century,
given the increasing globalization of the U.S. and world. The purpose
of this paper is to outline a pedagogical model for teaching cultural
competency that resulted in a significant increase in cultural
competency for MSW graduates at Western Kentucky University
(WKU). More specifically, this model is predicated on five specific
culturally sensitive principles and activities that were found to be
highly effective in conveying culturally relevant knowledge and skills
to MSW students at WKU. Future studies can assess the effectiveness
of these principles in other MSW programs across the U.S. and abroad.
Abstract: Routing in mobile ad hoc networks is a challenging task because nodes are free to move randomly. In DSR like all On- Demand routing algorithms, route discovery mechanism is associated with great delay. More Clearly in DSR routing protocol to send route reply packet, when current route breaks, destination seeks a new route. In this paper we try to change route selection mechanism proactively. We also define a link stability parameter in which a stability value is assigned to each link. Given this feature, destination node can estimate stability of routes and can select the best and more stable route. Therefore we can reduce the delay and jitter of sending data packets.
Abstract: Enterprises need a strategic plan to retain their skillful employees and provide their career management, sustain their existence, to have growth and leadership qualities, to reach the objectives to increase the value of the enterprise and to not to be affected from changing demographic structure. In the cases when the long term career expectations of skillful employees are in integrity with the enterprise’s interests, skill management process is directly related to the career management. With a long term plan, the enterprises should cover the labor force need that may arise in the future by using systematic career development programs and be prepared against developments for all times. Skill management is considered as a practice with which career mobility is planned for the skillful employee to be prepared for high level positions. Career planning is the planning of an employee’s progress or promotion within an organization for which he works by developing his knowledge, skills, abilities and motives. Career planning is considered as an individual’s planning his future and the position which he wants to have, the area which he want to work in, the objectives which he want to reach. With the aim of contributing the abovementioned discussion process, career management concept and its perception manner are examined in this study in a comparative manner.
Abstract: B2E portals represent a new class of web-based
information technologies which many organisations are introducing
in recent years to stay in touch with their distributed workforces and
enable them to perform value added activities for organisations.
However, actual usage of these emerging systems (measured using
suitable instruments) has not been reported in the contemporary
scholarly literature. We argue that many of the instruments to
measure usage of various types of IT-enabled information systems
are not directly applicable for B2E portals because they were
developed for the context of traditional mainframe and PC-based
information systems. It is therefore important to develop a new
instrument for web-based portal technologies aimed at employees. In
this article, we report on the development and initial qualitative
evaluation of an instrument that seeks to operationaise a set of
independent factors affecting the usage of portals by employees. The
proposed instrument is useful to IT/e-commerce researchers and
practitioners alike as it enhances their confidence in predicting
employee usage of portals in organisations.
Abstract: Surface sediment samples were collected from the
Canon River mouth, Taiwan and analyzed for polycyclic aromatic
hydrocarbons (PAHs). Total PAHs concentrations varied from 337 to
1,252 ng/g dry weight, with a mean concentration of 827 ng/g dry
weight. The spatial distribution of PAHs reveals that the PAHs
concentration is relatively high in the river mouth region, and
gradually diminishes toward the harbor region. Diagnostic ratios
showed that the possible source of PAHs in the Canon River mouth
could be petroleum combustion. The toxic equivalent concentrations
(TEQcarc) of PAHs varied from 47 to 112 ng TEQ/g dry weight. Higher
total TEQcarc values were found in the river mouth region. As
compared with the US Sediment Quality Guidelines (SQGs), the
observed levels of PAHs at Canon River mouth were lower than the
effects range low (ERL), and would probably not exert adverse
biological effects.
Abstract: In wavelet regression, choosing threshold value is a crucial issue. A too large value cuts too many coefficients resulting in over smoothing. Conversely, a too small threshold value allows many coefficients to be included in reconstruction, giving a wiggly estimate which result in under smoothing. However, the proper choice of threshold can be considered as a careful balance of these principles. This paper gives a very brief introduction to some thresholding selection methods. These methods include: Universal, Sure, Ebays, Two fold cross validation and level dependent cross validation. A simulation study on a variety of sample sizes, test functions, signal-to-noise ratios is conducted to compare their numerical performances using three different noise structures. For Gaussian noise, EBayes outperforms in all cases for all used functions while Two fold cross validation provides the best results in the case of long tail noise. For large values of signal-to-noise ratios, level dependent cross validation works well under correlated noises case. As expected, increasing both sample size and level of signal to noise ratio, increases estimation efficiency.
Abstract: The impact force of a rockfall is mainly determined by
its moving behavior and velocity, which are contingent on the rock
shape, slope gradient, height, and surface roughness of the moving
path. It is essential to precisely calculate the moving path of the
rockfall in order to effectively minimize and prevent damages caused
by the rockfall. By applying the Colorado Rockfall Simulation
Program (CRSP) program as the analysis tool, this research studies the
influence of three shapes of rock (spherical, cylindrical and discoidal)
and surface roughness on the moving path of a single rockfall. As
revealed in the analysis, in addition to the slope gradient, the geometry
of the falling rock and joint roughness coefficient ( JRC ) of the slope
are the main factors affecting the moving behavior of a rockfall. On a
single flat slope, both the rock-s bounce height and moving velocity
increase as the surface gradient increases, with a critical gradient value
of 1:m = 1 . Bouncing behavior and faster moving velocity occur more
easily when the rock geometry is more oval. A flat piece tends to cause
sliding behavior and is easily influenced by the change of surface
undulation. When JRC
Abstract: The building of a factory can be a strategic investment
owing to its long service life. An evaluation that only focuses, for
example, on payments for the building, the technical equipment of
the factory, and the personnel for the enterprise is – considering the
complexity of the system factory – not sufficient for this long-term
view. The success of an investment is secured, among other things,
by the attainment of nonmonetary goals, too, like transformability.
Such aspects are not considered in traditional investment calculations
like the net present value method. This paper closes this gap with the
enhanced economic evaluation (EWR) for factory planning. The
procedure and the first results of an application in a project are
presented.
Abstract: In this paper we present the deep study about the Bio-
Medical Images and tag it with some basic extracting features (e.g.
color, pixel value etc). The classification is done by using a nearest
neighbor classifier with various distance measures as well as the
automatic combination of classifier results. This process selects a
subset of relevant features from a group of features of the image. It
also helps to acquire better understanding about the image by
describing which the important features are. The accuracy can be
improved by increasing the number of features selected. Various
types of classifications were evolved for the medical images like
Support Vector Machine (SVM) which is used for classifying the
Bacterial types. Ant Colony Optimization method is used for optimal
results. It has high approximation capability and much faster
convergence, Texture feature extraction method based on Gabor
wavelets etc..
Abstract: Studying literature theme in the fields of tourism and
sustainable development and its importance in today world and their
criteria in architecture, here in this article we will also study the area
where the selected site is located; beside the Aab-Ask Village located
in Larijan region in Mazandaran province on the way to Haraz – one
of the tourism routes of Iran. After these studies by analyzing the
site, its strong potentials – such as mineral water springs (hot
springs), geothermal, landscapes and ideal climate - as a tourist
attraction spot in the region, and considering sustainable
development criteria – with regard to limits and available facilities –
a plan was offered that could change the region to provide the needs
of local people and in addition change it to a place where tourism
services is offered to the visitors and make it an acceptable sample of
stable building in Iran. Finally the reason to make design for this
complex is recovery of natural and historical values of Aab-Ask area
regarding development and sustainable architecture criteria in the
form of a functional sample which can be a suitable place to fulfill
this goal for having lots of strong points in attracting cultural and
sustainable tourist.
Abstract: Power Factor (PF) is one of the most important parameters in the electrical systems, especially in the water pumping station. The low power factor value of the water pumping stations causes penalty for the electrical bill. There are many methods use for power factor improvement. Each one of them uses a capacitor on the electrical power network. The position of the capacitors is varied depends on many factors such as; voltage level and capacitors rating. Adding capacitors on the motor terminals increase the supply power factor from 0.8 to more than 0.9 but these capacitors cause some problems for the electrical grid network, such as increasing the harmonic contents of the grid line voltage. In this paper the effects of using capacitors in the water pumping stations to improve the power factor value on the harmonic contents of the electrical grid network are studied. One of large water pumping stations in Kafr El-Shikh Governorate in Egypt was used, as a case study. The effect of capacitors on the line voltage harmonic contents is measured. The station uses capacitors to improve the PF values at the 1 lkv grid network. The power supply harmonics values are measured by a power quality analyzer at different loading conditions. The results showed that; the capacitors improved the power factor value of the feeder and its value increased than 0.9. But the THD values are increased by adding these capacitors. The harmonic analysis showed that; the 13th, 17th, and 19th harmonics orders are increased also by adding the capacitors.
Abstract: The RK5GL3 method is a numerical method for solving
initial value problems in ordinary differential equations, and is based
on a combination of a fifth-order Runge-Kutta method and 3-point
Gauss-Legendre quadrature. In this paper we describe the propagation
of local errors in this method, and show that the global order of
RK5GL3 is expected to be six, one better than the underlying Runge-
Kutta method.
Abstract: In this paper, we are going to determine the threshold levels of adaptive modulation in a burst by burst CDMA system by a suboptimum method so that the above method attempts to increase the average bit per symbol (BPS) rate of transceiver system by switching between the different modulation modes in variable channel condition. In this method, we choose the minimum values of average bit error rate (BER) and maximum values of average BPS on different values of average channel signal to noise ratio (SNR) and then calculate the relative threshold levels of them, so that when the instantaneous SNR increases, a higher order modulation be employed for increasing throughput and vise-versa when the instantaneous SNR decreases, a lower order modulation be employed for improvement of BER. In transmission step, by this adaptive modulation method, in according to comparison between obtained estimation of pilot symbols and a set of above suboptimum threshold levels, above system chooses one of states no transmission, BPSK, 4QAM and square 16QAM for modulation of data. The expected channel in this paper is a slow Rayleigh fading.
Abstract: An inverse geometry problem is solved to predict an
unknown irregular boundary profile. The aim is to minimize the
objective function, which is the difference between real and
computed temperatures, using three different versions of Conjugate
Gradient Method. The gradient of the objective function, considered
necessary in this method, obtained as a result of solving the adjoint
equation. The abilities of three versions of Conjugate Gradient
Method in predicting the boundary profile are compared using a
numerical algorithm based on the method. The predicted shapes show
that due to its convergence rate and accuracy of predicted values, the
Powell-Beale version of the method is more effective than the
Fletcher-Reeves and Polak –Ribiere versions.
Abstract: The effect of variable chemical reaction on heat and mass transfer characteristics over unsteady stretching surface embedded in a porus medium is studied. The governing time dependent boundary layer equations are transformed into ordinary differential equations containing chemical reaction parameter, unsteadiness parameter, Prandtl number and Schmidt number. These equations have been transformed into a system of first order differential equations. MATHEMATICA has been used to solve this system after obtaining the missed initial conditions. The velocity gradient, temperature, and concentration profiles are computed and discussed in details for various values of the different parameters.
Abstract: The work presents a development of EN338 strength classes for Strombosia pustulata, Pterygotama crocarpa, Nauclea diderrichii and Entandrophragma cyclindricum Nigerian timber species. The specimens for experimental measurements were obtained from the timber-shed at the famous Panteka market in Kaduna in the northern part of Nigeria. Laboratory experiments were conducted to determine the physical and mechanical properties of the selected timber species in accordance with EN 13183-1 and ASTM D193. The mechanical properties were determined using three point bending test. The generated properties were used to obtain the characteristic values of the material properties in accordance with EN384. The selected timber species were then classified according to EN 338. Strombosia pustulata, Pterygotama crocarpa, Nauclea diderrichii and Entandrophragma cyclindricum were assigned to strength classes D40, C14, D40 and D24 respectively. Other properties such as tensile and compressive strengths parallel and perpendicular to grains, shear strength as well as shear modulus were obtained in accordance with EN 338.
Abstract: The H.264/AVC video coding standard contains a number of advanced features. Ones of the new features introduced in this standard is the multiple intramode prediction. Its function exploits directional spatial correlation with adjacent block for intra prediction. With this new features, intra coding of H.264/AVC offers a considerably higher improvement in coding efficiency compared to other compression standard, but computational complexity is increased significantly when brut force rate distortion optimization (RDO) algorithm is used. In this paper, we propose a new fast intra prediction mode decision method for the complexity reduction of H.264 video coding. for luma intra prediction, the proposed method consists of two step: in the first step, we make the RDO for four mode of intra 4x4 block, based the distribution of RDO cost of those modes and the idea that the fort correlation with adjacent mode, we select the best mode of intra 4x4 block. In the second step, we based the fact that the dominating direction of a smaller block is similar to that of bigger block, the candidate modes of 8x8 blocks and 16x16 macroblocks are determined. So, in case of chroma intra prediction, the variance of the chroma pixel values is much smaller than that of luma ones, since our proposed uses only the mode DC. Experimental results show that the new fast intra mode decision algorithm increases the speed of intra coding significantly with negligible loss of PSNR.
Abstract: In this paper, we study the existence of solution of
the four-point boundary value problem for second-order differential
equations with impulses by using Leray-Schauder theory: