Abstract: Hyperglycaemia is a key factor that contributes to the
development of diabetes-related microvascular disease and a major
risk factor for endothelial dysfunction. In the current study, we have
explored glucose-induced abnormal intracellular calcium (Ca2+
i)
homeostasis in mouse microvessel endothelial cells (MMECs) in
high glucose (HG) (40mmol/L) versus control (low glucose, LG) (11
mmol/L). We demonstrated that the exposure of MMECs to HG for 3
days did not change basal Ca2+
i, however, there was a significant
increase of acetylcholine-induced Ca2+ entry. Western blots
illustrated that exposure to HG also increased STIM1 (Stromal
Interaction Molecule 1), but not Orai1 (the pore forming subunit),
protein expression levels. Although the link between HG-induced
changes in STIM1 expression, enhanced Ca2+ entry and endothelial
dysfunction requires further study, the current data are suggestive
that targeting these pathways may reduce the impact of HG on
endothelial function.
Abstract: Online Communities are an example of sociallyaware,
self-organising, complex adaptive computing systems.
The multi-agent systems (MAS) paradigm coordinated by
self-organisation mechanisms has been used as an effective
way for the simulation and modeling of such systems. In this
paper, we propose a model for simulating an online health
community using a situated multi-agent system approach,
governed by the co-evolution of the social and spatial
organisations of the agents.
Abstract: This paper presents a new color face image database
for benchmarking of automatic face detection algorithms and human
skin segmentation techniques. It is named the VT-AAST image
database, and is divided into four parts. Part one is a set of 286 color
photographs that include a total of 1027 faces in the original format
given by our digital cameras, offering a wide range of difference in
orientation, pose, environment, illumination, facial expression and
race. Part two contains the same set in a different file format. The
third part is a set of corresponding image files that contain human
colored skin regions resulting from a manual segmentation
procedure. The fourth part of the database has the same regions
converted into grayscale. The database is available on-line for
noncommercial use. In this paper, descriptions of the database
development, organization, format as well as information needed for
benchmarking of algorithms are depicted in detail.
Abstract: In the last few years, the Semantic Web gained scientific acceptance as a means of relationships identification in knowledge base, widely known by semantic association. Query about complex relationships between entities is a strong requirement for many applications in analytical domains. In bioinformatics for example, it is critical to extract exchanges between proteins. Currently, the widely known result of such queries is to provide paths between connected entities from data graph. However, they do not always give good results while facing the user need by the best association or a set of limited best association, because they only consider all existing paths but ignore the path evaluation. In this paper, we present an approach for supporting association discovery queries. Our proposal includes (i) a query language PmSPRQL which provides a multiparadigm query expressions for association extraction and (ii) some quantification measures making easy the process of association ranking. The originality of our proposal is demonstrated by a performance evaluation of our approach on real world datasets.
Abstract: Various solar energy technologies exist and they have
different application techniques in the generation of electrical power.
The widespread use of photovoltaic (PV) modules in such
technologies has been limited by relatively high costs and low
efficiencies. The efficiency of PV panels decreases as the operating
temperatures increase. This is due to the affect of solar intensity and
ambient temperature. In this work, Computational Fluid Dynamics
(CFD) was used to model the heat transfer from a standard PV panel
and thus determine the rate of dissipation of heat. To accurately
model the specific climatic conditions of the United Arab Emirates
(UAE), a case study of a new build green building in Dubai was
used. A finned heat pipe arrangement is proposed and analyzed to
determine the improved heat dissipation and thus improved
performance efficiency of the PV panel. A prototype of the
arrangement is built for experimental testing to validate the CFD
modeling and proof of concept.
Abstract: This paper describes Clinical Document Architecture Release Two (CDA R2) standard and a client application for messaging with SAĞLIK-NET project developed by The Ministry of Health of Turkey. CDA R2 , developed by Health Level 7 (HL7) organization and approved by American National Standards Institute (ANSI) in 2004, to standardize medical information to be able to share semantically and syntactically. In this study, a client application compatible with HL7 V3 for a project named SAĞLIKNET, aimed to build a National Health Information System by Turkey. Moreover, CDA conformance of this application will also be evaluated.
Abstract: Tandem mass spectrometry (MS/MS) is the engine
driving high-throughput protein identification. Protein mixtures possibly
representing thousands of proteins from multiple species are
treated with proteolytic enzymes, cutting the proteins into smaller
peptides that are then analyzed generating MS/MS spectra. The
task of determining the identity of the peptide from its spectrum
is currently the weak point in the process. Current approaches to de
novo sequencing are able to compute candidate peptides efficiently.
The problem lies in the limitations of current scoring functions. In this
paper we introduce the concept of proteome signature. By examining
proteins and compiling proteome signatures (amino acid usage) it is
possible to characterize likely combinations of amino acids and better
distinguish between candidate peptides. Our results strongly support
the hypothesis that a scoring function that considers amino acid usage
patterns is better able to distinguish between candidate peptides. This
in turn leads to higher accuracy in peptide prediction.
Abstract: This research presents a system for post processing of
data that takes mined flat rules as input and discovers crisp as well as
fuzzy hierarchical structures using Learning Classifier System
approach. Learning Classifier System (LCS) is basically a machine
learning technique that combines evolutionary computing,
reinforcement learning, supervised or unsupervised learning and
heuristics to produce adaptive systems. A LCS learns by interacting
with an environment from which it receives feedback in the form of
numerical reward. Learning is achieved by trying to maximize the
amount of reward received. Crisp description for a concept usually
cannot represent human knowledge completely and practically. In the
proposed Learning Classifier System initial population is constructed
as a random collection of HPR–trees (related production rules) and
crisp / fuzzy hierarchies are evolved. A fuzzy subsumption relation is
suggested for the proposed system and based on Subsumption Matrix
(SM), a suitable fitness function is proposed. Suitable genetic
operators are proposed for the chosen chromosome representation
method. For implementing reinforcement a suitable reward and
punishment scheme is also proposed. Experimental results are
presented to demonstrate the performance of the proposed system.
Abstract: This study aims to investigate how much both son and
daughter trust their father and what are the underlying reasons they
trust their father. The results revealed five main reasons why
Malaysian adolescents trust their father. Those reasons are related to
the role of father, father-child relationship, father-s characteristics,
father-s nurturing nature and father-s attitude and behavior. A total of
1022 students (males = 241, females = 781) from one of public
university in Sabah, Malaysia participated in the study. The
participants completed open-ended questionnaires developed by Kim
(2008), asking how much the adolescents trust their father, and the
reasons why they trust their father. The data was analysed by using
the indigenous psychology method proposed by [1] Findings of this
study revealed the pattern of trust towards father for both Malaysian
male and female adolescents. The results contributed new
information about Malaysian adolescents- trust towards their father
form the indigenous context. The implications of finding will be
discussed.
Abstract: Bootstrapping has gained popularity in different tests of hypotheses as an alternative in using asymptotic distribution if one is not sure of the distribution of the test statistic under a null hypothesis. This method, in general, has two variants – the parametric and the nonparametric approaches. However, issues on reliability of this method always arise in many applications. This paper addresses the issue on reliability by establishing a reliability measure in terms of quantiles with respect to asymptotic distribution, when this is approximately correct. The test of hypotheses used is Ftest. The simulated results show that using nonparametric bootstrapping in F-test gives better reliability than parametric bootstrapping with relatively higher degrees of freedom.
Abstract: The aim of this paper is to determine Frenet-Serret invariants of non-null curves in Lorentzian 5-space. First, we define a vector product of four vectors, by this way, we present a method to calculate Frenet-Serret invariants of the non-null curves. Additionally, an algebraic example of presented method is illustrated.
Abstract: Let G be a Hamiltonian graph. A factor F of G is called
a Hamiltonian factor if F contains a Hamiltonian cycle. In this paper,
two sufficient conditions are given, which are two neighborhood
conditions for a Hamiltonian graph G to have a Hamiltonian factor.
Abstract: Mega urban transport projects (MUTPs) are
increasingly being used in urban environments to ameliorate the
problem of congestion. However, a number of problems with regard
to mega projects have been identified. In particular the seemingly
institutionalised over estimation of economic benefits and persistent
cost over runs, could mean that the wrong projects are selected, and
that the projects that are selected cost more than they should. Studies
to date have produced a number of solutions to these problems,
perhaps most notably, the various methods for the inclusion of the
private sector in project provision. However the problems have
shown significant intractability in the face of these solutions. This
paper provides a detailed examination of some of the problems
facing mega projects and then examines Foucault-s theory of
'governmentality' as a possible frame of analysis which might shed
light on the intractability of the problems that have been identified,
through an identification of the art of government in which MUTPs
occur.
Abstract: The counter flow solar air heaters, with four
transverse fins and wire mesh layers are constructed and investigated
experimentally for thermal efficiency at a geographic location of
Cyprus in the city of Famagusta. The absorber plate is replaced by
sixteen steel wire mesh layers, 0.18 x 0.18cm in cross section
opening and a 0.02cm in diameter. The wire mesh layers arranged in
three groups, first and second include 6 layers, while the third include
4 layers. All layers fixed in the duct parallel to the glazing and each
group separated from the others by wood frame thickness of 0.5cm to
reduce the pressure drop. The transverse fins arranged in a way to
force the air to flow through the bed like eight letter path with flow
depth 3cm. The proposed design has increased the heat transfer rate,
but on other hand causes a high pressure drop. The obtained results
show that, for air mass flow rate range between 0.011-0.036kg/s, the
thermal efficiency increases with increasing the air mass flow. The
maximum efficiency obtained is 65.6% for the mass flow rate of
0.036kg/s. Moreover, the temperature difference between the outlet
flow and the ambient temperature, ΔT, reduces as the air mass flow
rate increase. The maximum difference between the outlet and
ambient temperature obtained was 43°C for double pass for minimum
mass flow rate of 0.011kg/s. Comparison with a conventional solar
air heater collector shows a significantly development in the thermal
efficiency.
Abstract: In manufacturing industries, development of measurement leads to increase the number of monitoring variables and eventually the importance of multivariate control comes to the fore. Statistical process control (SPC) is one of the most widely used as multivariate control chart. Nevertheless, SPC is restricted to apply in processes because its assumption of data as following specific distribution. Unfortunately, process data are composed by the mixture of several processes and it is hard to estimate as one certain distribution. To alternative conventional SPC, therefore, nonparametric control chart come into the picture because of the strength of nonparametric control chart, the absence of parameter estimation. SVDD based control chart is one of the nonparametric control charts having the advantage of flexible control boundary. However,basic concept of SVDD has been an oversight to the important of data characteristic, density distribution. Therefore, we proposed DW-SVDD (Density Weighted SVDD) to cover up the weakness of conventional SVDD. DW-SVDD makes a new attempt to consider dense of data as introducing the notion of density Weight. We extend as control chart using new proposed SVDD and a simulation study of various distributional data is conducted to demonstrate the improvement of performance.
Abstract: Fractional Fourier Transform is a generalization of the classical Fourier Transform which is often symbolized as the rotation in time- frequency plane. Similar to the product of time and frequency span which provides the Uncertainty Principle for the classical Fourier domain, there has not been till date an Uncertainty Principle for the Fractional Fourier domain for a generalized class of finite energy signals. Though the lower bound for the product of time and Fractional Fourier span is derived for the real signals, a tighter lower bound for a general class of signals is of practical importance, especially for the analysis of signals containing chirps. We hence formulate a mathematical derivation that gives the lower bound of time and Fractional Fourier span product. The relation proves to be utmost importance in taking the Fractional Fourier Transform with adaptive time and Fractional span resolutions for a varied class of complex signals.
Abstract: This paper describes a system, in which various methods of text summarizing can be adapted to Polish. A structure of the system is presented. A modular construction of the system and access to the system via the Internet are signaled.
Abstract: The fault current levels through the electric devices
have a significant impact on failure probability. New fault current
results in exceeding the rated capacity of circuit breaker and switching
equipments and changes operation characteristic of overcurrent relay.
In order to solve these problems, SFCL (Superconducting Fault
Current Limiter) has rising as one of new alternatives so as to improve
these problems. A fault current reduction differs depending on
installed location. Therefore, a location of SFCL is very important.
Also, SFCL decreases the fault current, and it prevents surrounding
protective devices to be exposed to fault current, it then will bring a
change of reliability. In this paper, we propose method which
determines the optimal location when SFCL is installed in power
system. In addition, the reliability about the power system which
SFCL was installed is evaluated. The efficiency and effectiveness of
this method are also shown by numerical examples and the reliability
indices are evaluated in this study at each load points. These results
show a reliability change of a system when SFCL was installed.
Abstract: Tasks of the work were study the possible E.coli
contamination in red deer meat, identify pathogenic strains from
isolated E.coli, determine their incidence in red deer meat and
determine the presence of VT1, VT2 and eaeA genes for the
pathogenic E.coli. 8 (10%) samples were randomly selected from 80
analysed isolates of E.coli and PCR reaction was performed on them.
PCR was done both on initial materials – samples of red deer meat -
and for already isolated liqueurs. Two of analysed venison samples
contain verotoxin-producing strains of E. coli. It means that this meat
is not safe to consumer. It was proven by the sequestration reaction of
E. coli and by comparison of the obtained results with the database of
microorganism genome available on the internet that the isolated
culture corresponds to region 16S rDNS of E. coli thus presenting
correctness of the microbiological methods.
Abstract: Recordings from recent earthquakes have provided evidence that ground motions in the near field of a rupturing fault differ from ordinary ground motions, as they can contain a large energy, or “directivity" pulse. This pulse can cause considerable damage during an earthquake, especially to structures with natural periods close to those of the pulse. Failures of modern engineered structures observed within the near-fault region in recent earthquakes have revealed the vulnerability of existing RC buildings against pulse-type ground motions. This may be due to the fact that these modern structures had been designed primarily using the design spectra of available standards, which have been developed using stochastic processes with relatively long duration that characterizes more distant ground motions. Many recently designed and constructed buildings may therefore require strengthening in order to perform well when subjected to near-fault ground motions. Fiber Reinforced Polymers are considered to be a viable alternative, due to their relatively easy and quick installation, low life cycle costs and zero maintenance requirements. The objective of this paper is to investigate the adequacy of Artificial Neural Networks (ANN) to determine the three dimensional dynamic response of FRP strengthened RC buildings under the near-fault ground motions. For this purpose, one ANN model is proposed to estimate the base shear force, base bending moments and roof displacement of buildings in two directions. A training set of 168 and a validation set of 21 buildings are produced from FEA analysis results of the dynamic response of RC buildings under the near-fault earthquakes. It is demonstrated that the neural network based approach is highly successful in determining the response.