Abstract: The mechanisms underlying the association between
obesity and asthma may be related to a decreased immunological
tolerance induced by a defective function of regulatory T cells
(Tregs). The aim of this study is to establish the potential link
between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T
helper cells (Ths) in children. This is a prospective case control
study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40) and
healthy children (n:40), who don't have any acute or chronic diseases,
were included in this study. Obese children were evaluated according
to WHO criteria. Asthmatic patients were chosen based on GINA
criteria. Parents were asked to fill up the questionnaire. Informed
consent forms were taken. Blood samples were marked with CD4+,
CD25+ and FoxP3+ in order to determine Tregs and Ths by flow
cytometric method. Statistical analyses were performed. p≤0.05 was
chosen as meaningful threshold. Tregs exhibiting anti-inflammatory
nature were significantly lower in obese (0,16%; p≤0,001), asthmatic
(0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than
the control group (0,38%). Ths were counted higher in asthma group
than the control (p≤0,01) and obese (p≤0,001) groups. T cell
immunity plays important roles in obesity and asthma pathogeneses.
Decreased numbers of Tregs found in obese, asthmatic and asthmatic
obese children may help to elucidate some questions in
pathophysiology of these diseases. For HOMA-IR levels, any
significant difference was not noted between control and obese
groups, but statistically higher values were found for obese
asthmatics. The values obtained in all groups were found to be below
the critical cut off points. This finding has made the statistically
significant difference observed between Tregs of obese, asthmatic,
obese asthmatic and control groups much more valuable. These
findings will be useful in diagnosis and treatment of these disorders
and future studies are needed. The production and propagation of
Tregs may be promising in alternative asthma and obesity treatments.
Abstract: Many organizations are investing in web applications
and technologies in order to be competitive, some of them could not
achieve its goals. The quality of web-based applications could play
an important role for organizations to be competitive. So the aim of
this study is to investigate the impact of quality of web-based
applications to achieve a competitive advantage. A new model has
been developed. An empirical investigation was performed on a
banking sector in Jordan to test the new model. The results show that
impact of web-based applications on competitive advantage is
significant. Finally, further work is planned to validate and evaluate
the proposed model using several domains.
Abstract: In the current work, a three-dimensional geometry of a
75% stenosed blood vessel is analyzed. Large eddy simulation (LES)
with the help of a dynamic subgrid scale Smagorinsky model is
applied to model the turbulent pulsatile flow. The geometry, the
transmural pressure and the properties of the blood and the elastic
boundary were based on clinical measurement data. For the flexible
wall model, a thin solid region is constructed around the 75%
stenosed blood vessel. The deformation of this solid region was
modelled as a deforming boundary to reduce the computational cost
of the solid model. Fluid-structure interaction is realized via a twoway
coupling between the blood flow modelled via LES and the
deforming vessel. The information of the flow pressure and the wall
motion was exchanged continually during the cycle by an arbitrary
Lagrangian-Eulerian method. The boundary condition of current time
step depended on previous solutions. The fluctuation of the velocity
in the post-stenotic region was analyzed in the study. The axial
velocity at normalized position Z=0.5 shows a negative value near
the vessel wall. The displacement of the elastic boundary was
concerned in this study. In particular, the wall displacement at the
systole and the diastole were compared. The negative displacement at
the stenosis indicates a collapse at the maximum velocity and the
deceleration phase.
Abstract: Background - The TrendCare Patient Dependency
System is currently used by a large number of maternity Services
across Australia, New Zealand and Singapore. In 2012, 2013 and
2014 validation studies were initiated in all three countries to validate
the acuity tools used for women in labour, and postnatal mothers and
babies. This paper will present the findings of the validation study.
Aim - The aim of this study was to; identify if the care hours
provided by the TrendCare acuity system was an accurate reflection
of the care required by women and babies; obtain evidence of
changes required to acuity indicators and/or category timings to
ensure the TrendCare acuity system remains reliable and valid across
a range of maternity care models in three countries.
Method - A non-experimental action research methodology was
used across maternity services in four District Health Boards in New
Zealand, a large tertiary and a large secondary maternity service in
Singapore and a large public maternity service in Australia.
Standardised data collection forms and timing devices were used to
collect midwife contact times, with women and babies included in the
study. Rejection processes excluded samples when care was not
completed/rationed, and contact timing forms were incomplete. The
variances between actual timed midwife/mother/baby contact and the
TrendCare acuity category times were identified and investigated.
Results - Thirty two (88.9%) of the 36 TrendCare acuity category
timings, fell within the variance tolerance levels when compared to
the actual timings recorded for midwifery care. Four (11.1%)
TrendCare categories provided less minutes of care than the actual
timings and exceeded the variance tolerance level. These were all
night shift category timings. Nine postnatal categories were not able
to be compared as the sample size for these categories was
statistically insignificant. 100% of labour ward TrendCare categories
matched actual timings for midwifery care, all falling within the
variance tolerance levels.
The actual time provided by core midwifery staff to assist lead
maternity carer (LMC) midwives in New Zealand labour wards
showed a significant deviation to previous studies. The findings of
the study demonstrated the need for additional time allocations in
TrendCare to accommodate an increased level of assistance given to
LMC midwives.
Conclusion - The results demonstrated the importance of regularly
validating the TrendCare category timings with actual timings of the
care hours provided. It was evident from the findings that variances
to models of care and length of stay in maternity units have increased
midwifery workloads on the night shift. The level of assistance
provided by the core labour ward staff to the LMC midwife has
increased substantially.
Outcomes - As a consequence of this study, changes were made to
the night duty TrendCare maternity categories, additional acuity
indicators were developed and times for assisting LMC midwives in
labour ward increased. The updated TrendCare version was delivered
to maternity services in 2014.
Abstract: Employer branding is considered as a useful tool for
addressing the global-local problem facing complex organisations
that have operations scattered across the globe and face challenges of
dealing with the local environment alongside. Despite being an
established field of study within the Western developed world, there
is little empirical evidence concerning the relevance of employer
branding to global companies that operate in the under-developed
economies. This paper fills this gap by gaining rich insight into the
implementation of employer branding programs in a foreign
multinational operating in Pakistan dealing with the global-local
problem. The study is qualitative in nature and employs semistructured
and focus group interviews with senior/middle managers
and local frontline employees to deeply examine the phenomenon in
case organisation. Findings suggest that authenticity is required in
employer brands to enable them to respond to the local needs thereby
leading to the resolution of the global-local problem. However, the
role of signaling theory is key to the development of authentic
employer brands as it stresses on the need to establish an efficient and
effective signaling environment where in signals travel in both
directions (from signal designers to receivers and backwards) and
facilitate firms with the global-local problem. The paper also
identifies future avenues of research for the employer branding field.
Abstract: Air-cooled Blast Furnace Slag Aggregate (BFSA) is
usually referred to as a material providing for unique properties of
concrete. On the other hand, negative influences are also presented in
many aspects. The freeze-thaw resistance of concrete is dependent on
many factors, including regional specifics and when a concrete mix is
specified it is still difficult to tell its exact freeze-thaw resistance due
to the different components affecting it. An important consideration
in working with BFSA is the granularity and whether slag is sorted or
not. The experimental part of the article represents a comparative
testing of concrete using both the sorted and unsorted BFSA through
the freeze-thaw resistance as an indicator of durability. Unsorted
BFSA is able to be successfully used for concretes as they are
specified for exposure class XF4 with providing that the type of
cement is precisely selected.
Abstract: This paper presents effects of distilled water, seawater
and sustained bending strains of 30% and 50% ultimate strain at
room temperature, on the durability of unidirectional pultruded
carbon fiber reinforced polymer (CFRP) plates. In this study,
dynamic mechanical analyzer (DMA) was used to investigate the
synergic effects of the immersions and bending strains on the viscoelastic
properties of (CFRP) such as storage modulus, tan delta and
glass transition temperature. The study reveals that the storage
modulus and glass transition temperature increase while tan delta
peak decreases in the initial stage of both immersions due to the
progression of curing. The storage modulus and Tg subsequently
decrease and tan delta increases due to the matrix plasticization. The
blister induced damages in the unstrained seawater samples enhance
water uptake and cause more serious degradation of Tg and storage
modulus than in water immersion. Increasing sustained bending
decreases Tg and storage modulus in a long run for both immersions
due to resin matrix cracking and debonding. The combined effects of
immersions and strains are not clearly reflected due to the statistical
effects of DMA sample sizes and competing processes of molecular
reorientation and postcuring.
Abstract: Image segmentation plays an important role in
medical imaging applications. Therefore, accurate methods are
needed for the successful segmentation of medical images for
diagnosis and detection of various diseases. In this paper, we have
used maximum entropy to achieve image segmentation. Maximum
entropy has been calculated using Shannon, Renyi and Tsallis
entropies. This work has novelty based on the detection of skin lesion
caused by the bite of a parasite called Sand Fly causing the disease is
called Cutaneous Leishmaniasis.
Abstract: This paper describes the issues relating to the role of
the flash flood early warning system provided by the Malaysian
Government to the communities in Malaysia, specifically during the
flash flood disaster in the Cameron Highlands, Malaysia. Normally,
flash flood disasters can occur as a result of heavy rainfall in an area,
and that water may possibly cause flooding via streams or narrow
channels. The focus of this study is the flash flood disaster which
occurred on 23 October 2013 in the Cameron Highlands, and as a
result the Sungai Bertam overflowed after the release of water from
the Sultan Abu Bakar Dam. This release of water from the dam
caused flash flooding which led to damage to properties and also the
death of residents and livestock in the area. Therefore, the effort of
this study is to identify the perceptions of the flash flood victims on
the role of the flash flood early warning system. For the purposes of
this study, data were gathered through face-to-face interviews from
those flood victims who were willing to participate in this study. This
approach helped the researcher to glean in-depth information about
their feelings and perceptions of the role of the flash flood early
warning system offered by the government. The data were analysed
descriptively and the findings show that the respondents of 22 flood
victims believe strongly that the flash flood early warning system was
confusing and dysfunctional, and communities had failed to response
positively to it. Therefore, most of the communities were not well
prepared for the releasing of water from the dam which caused
property damage, and 3 people were killed in the Cameron Highland
flash flood disaster.
Abstract: Specific leaf area (SLA; cm2leaf g-1leaf) the ratio of leaf
area to leaf dry mass is a key ecophysiological parameter influencing
leaf physiology, photosynthesis, and whole plant carbon gain and
also can be used as a rapid and diagnostic tool. In this study, two
species of soluble inorganic selenium forms, selenite (Se^IV) and
selenate (Se^VI) at different concentrations were investigated on maize
plants that were growing in nutrient solutions during 2 weeks and at
the end of the experiment, amounts of SLA for first and second
leaves of maize were measured. In accordance with the results we
observed that our regarded Se concentrations in both forms of Se^IV
and Se^VI were not effective on maize plants’ SLA significantly
although high level of 3 mg.kg-1 Se^IV had negative affect on growth
of the samples that had been treated by it but about Se^VI samples we
did not observe this state and our different considered Se^VI
concentrations were not toxic for maize plants.
Abstract: The paper discusses mineral water consumer market
and development policy in Georgia, the tools and measures, which
will contribute to production of mineral waters and increase its
export.
The paper studies and analyses current situation in mineral water
production sector as well as the factors affecting increase and
reduction of its export. It’s noted that in order to gain and maintain
competitive advantage, it’s necessary to provide continuous supply of
high quality goods with modern design, open new distribution
channels to enter new markets, carry out broad promotional activities,
organize e-commerce. Economic policy plays an important role in
protecting markets from counterfeit goods. The state also plays an
important role in attracting foreign direct investments. Stable
business environment and export oriented strategy is the basis for the
country’s economic growth.
Based on the research, the paper suggests the strategy for
improving competitiveness of Georgian mineral waters; relevant
conclusions and recommendations are provided.
Abstract: Freshly laid eggs from green turtles, Chelonia mydas,
were randomly collected from Ras Al-Hadd Reserve, Oman.
Eggshells taken from eggs and sand collected from the body chamber
were analyzed for eight heavy metals (Al, Br, Cd, Co, Cu, Fe, S, and
Zn) using inductively coupled plasma mass spectrometry (ICP).
Heavy metal concentrations varied significantly (P
Abstract: The paper deals with possibilities of interpretation of
iron ore reducibility tests. It presents a mathematical model
developed at Centre ENET, VŠB – Technical University of Ostrava,
Czech Republic for an evaluation of metallurgical material of blast
furnace feedstock such as iron ore, sinter or pellets. According to the
data from the test, the model predicts its usage in blast furnace
technology and its effects on production parameters of shaft
aggregate. At the beginning, the paper sums up the general concept
and experience in mathematical modelling of iron ore reduction. It
presents basic equation for the calculation and the main parts of the
developed model. In the experimental part, there is an example of
usage of the mathematical model. The paper describes the usage of
data for some predictive calculation. There are presented material,
method of carried test of iron ore reducibility. Then there are
graphically interpreted effects of used material on carbon
consumption, rate of direct reduction and the whole reduction
process.
Abstract: Experimental study on slicing of sapphire with fixed
abrasive diamond wire saw was conducted in this paper. The process
parameters were optimized through orthogonal experiment of three
factors and four levels. The effects of wire speed, feed speed and
tension pressure on the surface roughness were analyzed. Surface
roughness in cutting direction and feed direction were both detected.
The results show that feed speed plays the most significant role on the
surface roughness of sliced sapphire followed by wire speed and
tension pressure. The optimized process parameters are as follows:
wire speed 1.9 m/s, feed speed 0.187 mm/min and tension pressure
0.18 MPa. In the end, the results were verified by analysis of variance.
Abstract: Significant quota of Municipal Electrical Energy
consumption is related to Decentralized Air Conditioning which is
mostly provided by evaporative coolers. So the aim is to optimize
design of air conditioners to increase their efficiencies. To achieve
this goal, results of practical standardized tests for 40 evaporative
coolers in different types collected and simultaneously results for
same coolers based on one of EER (Energy Efficiency Ratio)
modeling styles are figured out. By comparing experimental results
of different coolers standardized tests with modeling results,
preciseness of used model is assessed and after comparing gained
preciseness with international standards based on EER for cooling
capacity, aeration, and also electrical energy consumption, energy
label from A (most effective) to G (less effective) is classified; finally
needed methods to optimize energy consumption and coolers’
classification are provided.
Abstract: This exploratory study gives an overview of the
evolution of the main financial and performance indicators of the
Academic Spin-Off’s and High Growth Academic Spin-Off’s in year
3 and year 6 after its creation in the region of Catalonia in Spain. The
study compares and evaluates results of these different measures of
performance and the degree of success of these companies for each
University.
We found that the average Catalonian Academic Spin-Off is small
and have not achieved the sustainability stage at year 6. On the
contrary, a small group of High Growth Academic Spin-Off’s
exhibits robust performance with high profits in year 6. Our results
support the need to increase selectivity and support for these
companies especially near year 3, because are the ones that will bring
wealth and employment. University role as an investor has rigid
norms and habits that impede an efficient economic return from their
ASO investment.
Universities with high performance on sales and employment in
year 3 not always could sustain this growth in year 6 because their
ASO’s are not profitable. On the contrary, profitable ASO exhibit
superior performance in all measurement indicators in year 6. We
advocate the need of a balanced growth (with profits) as a way to
obtain subsequent continuous growth.
Abstract: In this paper, we introduced a gradient-based inverse
solver to obtain the missing boundary conditions based on the
readings of internal thermocouples. The results show that the method
is very sensitive to measurement errors, and becomes unstable when
small time steps are used. The artificial neural networks are shown to
be capable of capturing the whole thermal history on the run-out
table, but are not very effective in restoring the detailed behavior of
the boundary conditions. Also, they behave poorly in nonlinear cases
and where the boundary condition profile is different.
GA and PSO are more effective in finding a detailed
representation of the time-varying boundary conditions, as well as in
nonlinear cases. However, their convergence takes longer. A
variation of the basic PSO, called CRPSO, showed the best
performance among the three versions. Also, PSO proved to be
effective in handling noisy data, especially when its performance
parameters were tuned. An increase in the self-confidence parameter
was also found to be effective, as it increased the global search
capabilities of the algorithm. RPSO was the most effective variation
in dealing with noise, closely followed by CRPSO. The latter
variation is recommended for inverse heat conduction problems, as it
combines the efficiency and effectiveness required by these
problems.
Abstract: In the past researchers have questioned the
effectiveness of ethics training in higher education. Also, there are
observations that support the view that ethical behaviour (range of
actions)/ethical decision making models used in the past make use of
vignettes to explain ethical behaviour. The understanding remains in
the perspective that these vignettes play a limited role in determining
individual intentions and not actions. Some authors have also agreed
that there are possibilities of differences in one’s intentions and
actions. This paper makes an attempt to fill those gaps by evaluating
real actions rather than intentions. In a way this study suggests the
use of an experiential methodology to explore Berlo’s model of
communication as an action along with orchestration of various
principles. To this endeavor, an attempt was made to use
conversational analysis in the pursuance of evaluating ethical
decision making behaviour among students and middle level
managers. The process was repeated six times with the set of an
average of 15 participants. Similarities have been observed in the
behaviour of students and middle level managers that calls for
understanding that both the groups of individuals have no cognizance
of their actual actions. The deliberations derived out of conversation
were taken a step forward for meta-ethical evaluations to portray a
clear picture of ethical behaviour among participants. This study
provides insights for understanding demonstrated unconscious human
behaviour which may fortuitously be termed both ethical and
unethical.
Abstract: These days customer satisfaction plays vital role in
any business. When customer searches for a product, significantly a
junk of irrelevant information is what is given, leading to customer
dissatisfaction. To provide exactly relevant information on the
searched product, we are proposing a model of KaaS (Knowledge as
a Service), which pre-processes the information using decision
making paradigm using Multi-agents.
Information obtained from various sources is taken to derive
knowledge and they are linked to Cloud to capture new idea. The
main focus of this work is to acquire relevant information
(knowledge) related to product, then convert this knowledge into a
service for customer satisfaction and deploy on cloud.
For achieving these objectives we are have opted to use multi
agents. They are communicating and interacting with each other,
manipulate information, provide knowledge, to take decisions. The
paper discusses about KaaS as an intelligent approach for Knowledge
acquisition.
Abstract: The main purpose of this paper is to determine the
applicability of the constitutional social rights in the so-called
horizontal relations, i.e. the relations between private entities.
Nowadays the constitutional rights are more and more often violated
by private entities and not only by the state. The private entities
interfere with the privacy of individuals, limit their freedom of
expression or disturb their peaceful gatherings. International
corporations subordinate individuals in a way which may limit their
constitutional rights. These new realities determine the new role of
the constitution in protecting human rights.
The paper will aim at answering two important questions. Firstly,
are the private entities obliged to respect the constitutional social
rights of other private entities and can they be liable for violation of
these rights? Secondly, how the constitutional social rights can
receive horizontal effect? Answers to these questions will have a
significant meaning for the popularisation of the practice of applying
the Constitution among the citizens as well as for the courts which
settle disputes between them.