Abstract: MinC plays an important role in bacterial cell division
system by inhibiting FtsZ assembly. However, the molecular
mechanism of the action is poorly understood. E. coli MinC Nterminus
domain was purified and crystallized using 1.4 M sodium
citrate pH 6.5 as a precipitant. X-ray diffraction data was collected
and processed to 2.3 Å from a native crystal. The crystal belonged to
space group P212121, with the unit cell parameters a = 52.7, b = 54.0,
c = 64.7 Å. Assuming the presence of two molecules in the
asymmetric unit, the Matthews coefficient value is 1.94 Å3 Da-1,
which corresponds to a solvent content of 36.5%. The overall
structure of MinCN is observed as a dimer form through anti-parallel
ß-strand interaction.
Abstract: Analytical solution of the first-order and third-order
shear deformation theories are developed to study the free vibration
behavior of simply supported functionally graded plates. The
material properties of plate are assumed to be graded in the thickness
direction as a power law distribution of volume fraction of the
constituents. The governing equations of functionally graded plates
are established by applying the Hamilton's principle and are solved
by using the Navier solution method. The influence of side-tothickness
ratio and constituent of volume fraction on the natural
frequencies are studied. The results are validated with the known
data in the literature.
Abstract: The paper proposes an approach using genetic algorithm for computing the region based image similarity. The image is denoted using a set of segmented regions reflecting color and texture properties of an image. An image is associated with a family of image features corresponding to the regions. The resemblance of two images is then defined as the overall similarity between two families of image features, and quantified by a similarity measure, which integrates properties of all the regions in the images. A genetic algorithm is applied to decide the most plausible matching. The performance of the proposed method is illustrated using examples from an image database of general-purpose images, and is shown to produce good results.
Abstract: In this paper back-propagation artificial neural network
(BPANN) is employed to predict the deformation of the upsetting
process. To prepare a training set for BPANN, some finite element
simulations were carried out. The input data for the artificial neural
network are a set of parameters generated randomly (aspect ratio d/h,
material properties, temperature and coefficient of friction). The
output data are the coefficient of polynomial that fitted on barreling
curves. Neural network was trained using barreling curves generated
by finite element simulations of the upsetting and the corresponding
material parameters. This technique was tested for three different
specimens and can be successfully employed to predict the
deformation of the upsetting process
Abstract: Heterogeneity of solid waste characteristics as well as the complex processes taking place within the landfill ecosystem motivated the implementation of soft computing methodologies such as artificial neural networks (ANN), fuzzy logic (FL), and their combination. The present work uses a hybrid ANN-FL model that employs knowledge-based FL to describe the process qualitatively and implements the learning algorithm of ANN to optimize model parameters. The model was developed to simulate and predict the landfill gas production at a given time based on operational parameters. The experimental data used were compiled from lab-scale experiment that involved various operating scenarios. The developed model was validated and statistically analyzed using F-test, linear regression between actual and predicted data, and mean squared error measures. Overall, the simulated landfill gas production rates demonstrated reasonable agreement with actual data. The discussion focused on the effect of the size of training datasets and number of training epochs.
Abstract: The inherent iterative nature of product design and development poses significant challenge to reduce the product design and development time (PD). In order to shorten the time to market, organizations have adopted concurrent development where multiple specialized tasks and design activities are carried out in parallel. Iterative nature of work coupled with the overlap of activities can result in unpredictable time to completion and significant rework. Many of the products have missed the time to market window due to unanticipated or rather unplanned iteration and rework. The iterative and often overlapped processes introduce greater amounts of ambiguity in design and development, where the traditional methods and tools of project management provide less value. In this context, identifying critical metrics to understand the iteration probability is an open research area where significant contribution can be made given that iteration has been the key driver of cost and schedule risk in PD projects. Two important questions that the proposed study attempts to address are: Can we predict and identify the number of iterations in a product development flow? Can we provide managerial insights for a better control over iteration? The proposal introduces the concept of decision points and using this concept intends to develop metrics that can provide managerial insights into iteration predictability. By characterizing the product development flow as a network of decision points, the proposed research intends to delve further into iteration probability and attempts to provide more clarity.
Abstract: The mechanical and tribological properties in WC-Co
coatings are strongly affected by hardness and elasticity
specifications. The results revealed the effect of spraying distance on
microhardness and elasticity modulus of coatings. The metallurgical
studies have been made on coated samples using optical microscopy,
scanning electron microscopy (SEM).
Abstract: Under-representation of women in leadership positions" is still a general phenomenon in Germany despite the high number of implemented measures. The under-representation of female executives in the aviation sector is even worse. In this context our research hypothesis is that the representation and acceptance of women in management positions is determined by corporate culture.
Abstract: The aim of the present study is to analyze the generation of osteoporotic vertebral bone induced by lack of calcium during growth period and analyze its effects for disc degeneration, based on biomechanical and histomorphometrical study. Mechanical and histomorphological characteristics of lumbar vertebral bones and discs of rats with calcium free diet (CFD) were detected and tracked by using high resolution in-vivo micro-computed tomography (in-vivo micro-CT), finite element (FE) and histological analysis. Twenty female Sprague-Dawley rats (6 weeks old, approximate weight 170g) were randomly divided into two groups (CFD group: 10, NOR group: 10). The CFD group was maintained on a refmed calcium-controlled semisynthetic diet without added calcium, to induce osteoporosis. All lumbar (L 1-L6) were scanned by using in vivo micro-CT with 35i.un resolution at 0, 4, 8 weeks to track the effects of CFD on the generation of osteoporosis. The fmdings of the present study indicated that calcium insufficiency was the main factor in the generation of osteoporosis and it induced lumbar vertebral disc degeneration. This study is a valuable experiment to firstly evaluate osteoporotic vertebral bone and disc degeneration induced by lack of calcium during growth period from a biomechanical and histomorphometrical point of view.
Abstract: Shortening of natural resources will impose greater
limitations of electric energy consumption in various fields including
water treatment technologies. Small water treatment installations
supplied with electric energy from solar sources are perfect example of
zero-emission technology. Possibility of solar energy application, as
one of the alternative energy resources for decontamination processes
is strongly dependent on geographical location. Various examples of
solar driven water purification systems are given and design of
solar-water treatment installation based on ozone for the geographical
conditions in Poland are presented.
Abstract: Over half of the total electricity consumption is used in buildings. Air-conditioning and electric lighting are the two main resources of electricity consumption in high rise buildings. One way to reduce electricity consumption would be to limit heat gain into buildings, therefore reduce the demand for air-conditioning during hot summer months especially in hot regions. On the other hand natural daylight can be used to reduce the use of electricity for artificial lighting. In this paper effective factors on minimizing heat gain and achieving required day light were reviewed .As daylight always accompanied by solar heat gain. Also interactions between heat gain and daylight were discussed through previous studies and equations which are related to heat gain and day lighting especially in high rise buildings. As a result importance of building-s form and its component on energy consumption in buildings were clarified.
Abstract: Off-grid Photovoltaic (PV) systems are empowering
technology in underdeveloped countries like Ethiopia where many
people live far away from the modern world. Where there is
relatively low energy consumption, providing energy from grid
systems is not commercially cost-effective. As a result, significant
people groups worldwide stay without access to electricity. One
remote village in northern Ethiopia was selected by the United
Nations for a pilot project to improve its living conditions. As part of
this comprehensive project, an intelligent charge controller circuit for
Off-grid PV systems was designed for the clinic in that village. In
this paper, design aspects of an intelligent charge controller unit and
its load driver circuits are discussed for an efficient utilization of PVbased
supply systems.
Abstract: Environmental pollution problems have been globally
main concern in all fields including economy, society and culture into
the 21st century. Beginning with the Kyoto Protocol, the reduction on
the emissions of greenhouse gas such as CO2 and SOX has been a
principal challenge of our day. As most buildings unlike durable goods
in other industries have a characteristic and long life cycle, they
consume energy in quantity and emit much CO2. Thus, for green
building construction, more research is needed to reduce the CO2
emissions at each stage in the life cycle. However, recent studies are
focused on the use and maintenance phase. Also, there is a lack of
research on the initial design stage, especially the structure design.
Therefore, in this study, we propose an optimal design plan
considering CO2 emissions and cost in composite buildings
simultaneously by applying to the structural design of actual building.
Abstract: In order to assess optical fiber reliability in different environmental and stress conditions series of testing are performed simulating overlapping of chemical and mechanical controlled varying factors. Each series of testing may be compared using statistical processing: i.e. Weibull plots. Due to the numerous data to treat, a software application has appeared useful to interpret selected series of experiments in function of envisaged factors. The current paper presents a software application used in the storage, modelling and interpretation of experimental data gathered from optical fibre testing. The present paper strictly deals with the software part of the project (regarding the modelling, storage and processing of user supplied data).
Abstract: In the paper the mathematical model of tumor
growth is considered. New capillary network formation,
which supply cancer cells with the nutrients, is taken into the
account. A formula estimating a tumor growth in connection
with the number of capillaries is obtained.
Abstract: This paper presents the simulation results of electric field and potential distributions along surface of silicone rubber polymer insulators under clean and various contamination conditions with/without water droplets. Straight sheds insulator having leakage distance 290 mm was used in this study. Two type of contaminants, playwood dust and cement dust, have been studied the effect of contamination on the insulator surface. The objective of this work is to comparison the effect of contamination on potential and electric field distributions along the insulator surface when water droplets exist on the insulator surface. Finite element method (FEM) is adopted for this work. The simulation results show that contaminations have no effect on potential distribution along the insulator surface while electric field distributions are obviously depended on contamination conditions.
Abstract: The paper analyzes the large power transformer unit regimes, indicating the criteria for the management of the voltage operating conditions, as well as the change in the operating conditions with the load connected to the secondary winding of the transformer unit. Further, the paper presents the software application for the evaluation of the transformer unit operation under different conditions. The software application was developed by means of virtual instrumentation.
Abstract: Recycling of aluminum alloys often decrease fluidity,
consequently influence the castability of the alloy. In this study, the
fluidity of Al-Zn alloys, such as the standard A713 alloy with and
without scrap addition has been investigated. The scrap added was
comprised of contaminated alloy turning chips. Fluidity
measurements were performed with double spiral fluidity test
consisting of gravity casting of double spirals in green sand moulds
with good reproducibility. The influence of recycled alloy on fluidity
has been compared with that of the virgin alloy and the results
showed that the fluidity decreased with the increase in recycled alloy
at minimum pouring temperatures. Interestingly, an appreciable
improvement in the fluidity was observed at maximum pouring
temperature, especially for coated spirals.
Abstract: With the advent of social web initiatives, some argued
that these new emerging tools might be useful in tacit knowledge
sharing through providing interactive and collaborative technologies.
However, there is still a poverty of literature to understand how and
what might be the contributions of social media in facilitating tacit
knowledge sharing. Therefore, this paper is intended to theoretically
investigate and map social media concepts and characteristics with
tacit knowledge creation and sharing requirements. By conducting a
systematic literature review, five major requirements found that need
to be present in an environment that involves tacit knowledge
sharing. These requirements have been analyzed against social media
concepts and characteristics to see how they map together. The
results showed that social media have abilities to comply some of the
main requirements of tacit knowledge sharing. The relationships have
been illustrated in a conceptual framework, suggesting further
empirical studies to acknowledge findings of this study.
Abstract: The effects of chitosan, a biodegradable polymer,
were studied in Grammatophyllum speciosum protocorm-like bodies
(PLBs) in vitro culture. The chitosan concentration of 0, 5, 10, 15,
20, 25, 50 or 100 mg/l were supplemented in half-strength Murashige
and Skoog (1/2 MS) liquid or on agar media containing 2% (w/v)
sucrose. The results showed that liquid medium supplemented with
15 mg/l chitosan showed the highest relative growth rate (7-fold
increase) of PLBs. On 1/2 MS agar medium supplemented with 25
mg/l chitosan gave the highest relative growth rate (4-fold increase).
The relative growth rate of G. speciosum PLBs on agar medium was
significantly lower than that in liquid medium. Moreover, chitosan,
supplemented to agar medium promoted shoot formation but not
rooting. However, supplementation at too high a level, such as 100
mg/l can inhibit growth and kill PLBs.