Abstract: This article demonstrated development of
controlled release system of an NSAID drug, Diclofenac
sodium employing different ratios of Ethyl cellulose.
Diclofenac sodium and ethyl cellulose in different proportions
were processed by microencapsulation based on phase
separation technique to formulate microcapsules. The
prepared microcapsules were then compressed into tablets to
obtain controlled release oral formulations. In-vitro evaluation
was performed by dissolution test of each preparation was
conducted in 900 ml of phosphate buffer solution of pH 7.2
maintained at 37 ± 0.5 °C and stirred at 50 rpm. At predetermined
time intervals (0, 0.5, 1.0, 1.5, 2, 3, 4, 6, 8, 10, 12,
16, 20 and 24 hrs). The drug concentration in the collected
samples was determined by UV spectrophotometer at 276 nm.
The physical characteristics of diclofenac sodium
microcapsules were according to accepted range. These were
off-white, free flowing and spherical in shape. The release
profile of diclofenac sodium from microcapsules was found to
be directly proportional to the proportion of ethylcellulose and
coat thickness. The in-vitro release pattern showed that with
ratio of 1:1 and 1:2 (drug: polymer), the percentage release of
drug at first hour was 16.91 and 11.52 %, respectively as
compared to 1:3 which is only 6.87 % with in this time. The
release mechanism followed higuchi model for its release
pattern. Tablet Formulation (F2) of present study was found
comparable in release profile the marketed brand Phlogin-SR,
microcapsules showed an extended release beyond 24 h.
Further, a good correlation was found between drug release
and proportion of ethylcellulose in the microcapsules.
Microencapsulation based on coacervation found as good
technique to control release of diclofenac sodium for making
the controlled release formulations.
Abstract: Program slicing is the task of finding all statements in
a program that directly or indirectly influence the value of a variable
occurrence. The set of statements that can affect the value of a
variable at some point in a program is called a program backward
slice. In several software engineering applications, such as program
debugging and measuring program cohesion and parallelism, several
slices are computed at different program points. The existing
algorithms for computing program slices are introduced to compute a
slice at a program point. In these algorithms, the program, or the
model that represents the program, is traversed completely or
partially once. To compute more than one slice, the same algorithm
is applied for every point of interest in the program. Thus, the same
program, or program representation, is traversed several times.
In this paper, an algorithm is introduced to compute all forward
static slices of a computer program by traversing the program
representation graph once. Therefore, the introduced algorithm is
useful for software engineering applications that require computing
program slices at different points of a program. The program
representation graph used in this paper is called Program Dependence
Graph (PDG).
Abstract: In this study, an inland metropolitan area, Gwangju, in Korea was selected to assess the amplification potential of earthquake motion and provide the information for regional seismic countermeasure. A geographic information system-based expert system was implemented for reliably predicting the spatial geotechnical layers in the entire region of interesting by building a geo-knowledge database. Particularly, the database consists of the existing boring data gathered from the prior geotechnical projects and the surface geo-knowledge data acquired from the site visit. For practical application of the geo-knowledge database to estimate the earthquake hazard potential related to site amplification effects at the study area, seismic zoning maps on geotechnical parameters, such as the bedrock depth and the site period, were created within GIS framework. In addition, seismic zonation of site classification was also performed to determine the site amplification coefficients for seismic design at any site in the study area. KeywordsEarthquake hazard, geo-knowledge, geographic information system, seismic zonation, site period.
Abstract: Structured catalysts formed from the growth of
zeolites on substrates is an area of increasing interest due to the
increased efficiency of the catalytic process, and the ability to
provide superior heat transfer and thermal conductivity for both
exothermic and endothermic processes.
However, the generation of structured catalysts represents a
significant challenge when balancing the relationship variables
between materials properties and catalytic performance, with the
Na2O, H2O and Al2O3 gel composition paying a significant role in
this dynamic, thereby affecting the both the type and range of
application.
The structured catalyst films generated as part of this
investigation have been characterised using a range of techniques,
including X-ray diffraction (XRD), Electron microscopy (SEM),
Energy Dispersive X-ray analysis (EDX) and Thermogravimetric
Analysis (TGA), with the transition from oxide-on-alloy wires to
hydrothermally synthesised uniformly zeolite coated surfaces being
demonstrated using both SEM and XRD. The robustness of the
coatings has been ascertained by subjecting these to thermal cycling
(ambient to 550oC), with the results indicating that the synthesis time
and gel compositions have a crucial effect on the quality of zeolite
growth on the FeCrAlloy wires.
Finally, the activity of the structured catalyst was verified by a
series of comparison experiments with standard zeolite Y catalysts in
powdered pelleted forms.
Abstract: In this study, we developed an algorithm for detecting
seam cracks in a steel plate. Seam cracks are generated in the edge
region of a steel plate. We used the Gabor filter and an adaptive double
threshold method to detect them. To reduce the number of pseudo
defects, features based on the shape of seam cracks were used. To
evaluate the performance of the proposed algorithm, we tested 989
images with seam cracks and 9470 defect-free images. Experimental
results show that the proposed algorithm is suitable for detecting seam
cracks. However, it should be improved to increase the true positive
rate.
Abstract: In the highly competitive and rapidly changing global
marketplace, independent organizations and enterprises often come
together and form a temporary alignment of virtual enterprise in a
supply chain to better provide products or service. As firms adopt the
systems approach implicit in supply chain management, they must
manage the quality from both internal process control and external
control of supplier quality and customer requirements. How to
incorporate quality management of upstream and downstream supply
chain partners into their own quality management system has recently
received a great deal of attention from both academic and practice.
This paper investigate the collaborative feature and the entities-
relationship in a supply chain, and presents an ontology of
collaborative supply chain from an approach of aligning
service-oriented framework with service-dominant logic. This
perspective facilitates the segregation of material flow management
from manufacturing capability management, which provides a
foundation for the coordination and integration of the business process
to measure, analyze, and continually improve the quality of products,
services, and process. Further, this approach characterizes the different
interests of supply chain partners, providing an innovative approach to
analyze the collaborative features of supply chain. Furthermore, this
ontology is the foundation to develop quality management system
which internalizes the quality management in upstream and
downstream supply chain partners and manages the quality in supply
chain systematically.
Abstract: Sonogram images of normal and lymphocyte thyroid tissues have considerable overlap which makes it difficult to interpret and distinguish. Classification from sonogram images of thyroid gland is tackled in semiautomatic way. While making manual diagnosis from images, some relevant information need not to be recognized by human visual system. Quantitative image analysis could be helpful to manual diagnostic process so far done by physician. Two classes are considered: normal tissue and chronic lymphocyte thyroid (Hashimoto's Thyroid). Data structure is analyzed using K-nearest-neighbors classification. This paper is mentioned that unlike the wavelet sub bands' energy, histograms and Haralick features are not appropriate to distinguish between normal tissue and Hashimoto's thyroid.
Abstract: In this paper, we first introduce the new concept of completely semiprime fuzzy ideals of an ordered semigroup S, which is an extension of completely semiprime ideals of ordered semigroup S, and investigate some its related properties. Especially, we characterize an ordered semigroup that is a semilattice of simple ordered semigroups in terms of completely semiprime fuzzy ideals of ordered semigroups. Furthermore, we introduce the notion of semiprime fuzzy ideals of ordered semigroup S and establish the relations between completely semiprime fuzzy ideals and semiprime fuzzy ideals of S. Finally, we give a characterization of prime fuzzy ideals of an ordered semigroup S and show that a nonconstant fuzzy ideal f of an ordered semigroup S is prime if and only if f is twovalued, and max{f(a), f(b)} = inf f((aSb]), ∀a, b ∈ S.
Abstract: This paper describes the development of a fully
automated measurement software for antenna radiation pattern
measurements in a Compact Antenna Test Range (CATR). The
CATR has a frequency range from 2-40 GHz and the measurement
hardware includes a Network Analyzer for transmitting and
Receiving the microwave signal and a Positioner controller to control
the motion of the Styrofoam column. The measurement process
includes Calibration of CATR with a Standard Gain Horn (SGH)
antenna followed by Gain versus angle measurement of the Antenna
under test (AUT). The software is designed to control a variety of
microwave transmitter / receiver and two axis Positioner controllers
through the standard General Purpose interface bus (GPIB) interface.
Addition of new Network Analyzers is supported through a slight
modification of hardware control module. Time-domain gating is
implemented to remove the unwanted signals and get the isolated
response of AUT. The gated response of the AUT is compared with
the calibration data in the frequency domain to obtain the desired
results. The data acquisition and processing is implemented in
Agilent VEE and Matlab. A variety of experimental measurements
with SGH antennas were performed to validate the accuracy of
software. A comparison of results with existing commercial
softwares is presented and the measured results are found to be
within .2 dBm.
Abstract: An acoustic emission (AE) technique is useful for
detection of partial discharges (PDs) at a joint and a terminal section of
a cross-linked polyethylene (XLPE) cable. For AE technique, it is not
difficult to detect a PD using AE sensors. However, it is difficult to
grasp whether the detected AE signal is owing to a single discharge or
not. Additionally, when an AE technique is applied at a terminal
section of a XLPE cable in salt pollution district, for example, there is
possibility of detection of AE signals owing to creeping discharges on
the surface of electric power apparatus. In this study, we evaluated AE
signals in order to grasp what kind of information we can get from
detected AE signals. The results showed that envelop detection of AE
signal and a period which some AE signals were continuously detected
were good indexes for estimating state-of-discharge.
Abstract: This paper presents a new Hybrid Fuzzy (HF) PID type controller based on Genetic Algorithms (GA-s) for solution of the Automatic generation Control (AGC) problem in a deregulated electricity environment. In order for a fuzzy rule based control system to perform well, the fuzzy sets must be carefully designed. A major problem plaguing the effective use of this method is the difficulty of accurately constructing the membership functions, because it is a computationally expensive combinatorial optimization problem. On the other hand, GAs is a technique that emulates biological evolutionary theories to solve complex optimization problems by using directed random searches to derive a set of optimal solutions. For this reason, the membership functions are tuned automatically using a modified GA-s based on the hill climbing method. The motivation for using the modified GA-s is to reduce fuzzy system effort and take large parametric uncertainties into account. The global optimum value is guaranteed using the proposed method and the speed of the algorithm-s convergence is extremely improved, too. This newly developed control strategy combines the advantage of GA-s and fuzzy system control techniques and leads to a flexible controller with simple stricture that is easy to implement. The proposed GA based HF (GAHF) controller is tested on a threearea deregulated power system under different operating conditions and contract variations. The results of the proposed GAHF controller are compared with those of Multi Stage Fuzzy (MSF) controller, robust mixed H2/H∞ and classical PID controllers through some performance indices to illustrate its robust performance for a wide range of system parameters and load changes.
Abstract: The drastic increase in the usage of SMS technology
has led service providers to seek for a solution that enable users of
mobile devices to access services through SMSs. This has resulted in
the proposal of solutions towards SMS-based service invocation in
service oriented environments. However, the dynamic nature of
service-oriented environments coupled with sudden load peaks
generated by service request, poses performance challenges to
infrastructures for supporting SMS-based service invocation. To
address this problem we adopt load balancing techniques. A load
balancing model with adaptive load balancing and load monitoring
mechanisms as its key constructs is proposed. The load balancing
model then led to realization of Least Loaded Load Balancing
Framework (LLLBF). Evaluation of LLLBF benchmarked with round
robin (RR) scheme on the queuing approach showed LLLBF
outperformed RR in terms of response time and throughput.
However, LLLBF achieved better result in the cost of high
processing power.
Abstract: In this work we present a solution for DAGC (Digital
Automatic Gain Control) in WLAN receivers compatible to IEEE 802.11a/g standard. Those standards define communication in 5/2.4
GHz band using Orthogonal Frequency Division Multiplexing OFDM modulation scheme. WLAN Transceiver that we have used
enables gain control over Low Noise Amplifier (LNA) and a
Variable Gain Amplifier (VGA). The control over those signals is
performed in our digital baseband processor using dedicated hardware block DAGC. DAGC in this process is used to automatically control the VGA and LNA in order to achieve better
signal-to-noise ratio, decrease FER (Frame Error Rate) and hold the
average power of the baseband signal close to the desired set point.
DAGC function in baseband processor is done in few steps: measuring power levels of baseband samples of an RF signal,accumulating the differences between the measured power level and
actual gain setting, adjusting a gain factor of the accumulation, and
applying the adjusted gain factor the baseband values. Based on the measurement results of RSSI signal dependence to input power we have concluded that this digital AGC can be implemented applying
the simple linearization of the RSSI. This solution is very simple but also effective and reduces complexity and power consumption of the
DAGC. This DAGC is implemented and tested both in FPGA and in ASIC as a part of our WLAN baseband processor. Finally, we have integrated this circuit in a compact WLAN PCMCIA board based on MAC and baseband ASIC chips designed from us.
Abstract: In recent years, it has been proposed security
architecture for sensor network.[2][4]. One of these, TinySec by Chris
Kalof, Naveen Sastry, David Wagner had proposed Link layer security
architecture, considering some problems of sensor network. (i.e :
energy, bandwidth, computation capability,etc). The TinySec employs
CBC_mode of encryption and CBC-MAC for authentication based on
SkipJack Block Cipher. Currently, This TinySec is incorporated in the
TinyOS for sensor network security.
This paper introduces TinyHash based on general hash algorithm.
TinyHash is the module in order to replace parts of authentication and
integrity in the TinySec. it implies that apply hash algorithm on
TinySec architecture. For compatibility about TinySec, Components
in TinyHash is constructed as similar structure of TinySec. And
TinyHash implements the HMAC component for authentication and
the Digest component for integrity of messages. Additionally, we
define the some interfaces for service associated with hash algorithm.
Abstract: Flow field around hypersonic vehicles is very
complex and difficult to simulate. The boundary layers are squeezed
between shock layer and body surface. Resolution of boundary layer,
shock wave and turbulent regions where the flow field has high
values is difficult of capture. Detached eddy simulation (DES) is a
modification of a RANS model in which the model switches to a
subgrid scale formulation in regions fine enough for LES
calculations. Regions near solid body boundaries and where the
turbulent length scale is less than the maximum grid dimension are
assigned the RANS mode of solution. As the turbulent length scale
exceeds the grid dimension, the regions are solved using the LES
mode. Therefore the grid resolution is not as demanding as pure LES,
thereby considerably cutting down the cost of the computation. In
this research study hypersonic flow is simulated at Mach 8 and
different angle of attacks to resolve the proper boundary layers and
discontinuities. The flow is also simulated in the long wake regions.
Mesh is little different than RANS simulations and it is made dense
near the boundary layers and in the wake regions to resolve it
properly. Hypersonic blunt cone cylinder body with frustrum at angle
5o and 10 o are simulated and there aerodynamics study is performed
to calculate aerodynamics characteristics of different geometries. The
results and then compared with experimental as well as with some
turbulence model (SA Model). The results achieved with DES
simulation have very good resolution as well as have excellent
agreement with experimental and available data. Unsteady
simulations are performed for DES calculations by using duel time
stepping method or implicit time stepping. The simulations are
performed at Mach number 8 and angle of attack from 0o to 10o for
all these cases. The results and resolutions for DES model found
much better than SA turbulence model.
Abstract: Charge Simulation Method (CSM) is one of the very widely used numerical field computation technique in High Voltage (HV) engineering. The high voltage fields of varying non uniformities are encountered in practice. CSM programs being case specific, the simulation accuracies heavily depend on the user (programmers) experience. Here is an effort to understand CSM errors and evolve some guidelines to setup accurate CSM models, relating non uniformities with assignment factors. The results are for the six-point-charge model of sphere-plane gap geometry. Using genetic algorithm (GA) as tool, optimum assignment factors at different non uniformity factors for this model have been evaluated and analyzed. It is shown that the symmetrically placed six-point-charge models can be good enough to set up CSM programs with potential errors less than 0.1% when the field non uniformity factor is greater than 2.64 (field utilization factor less than 52.76%).
Abstract: This paper presents a simple method for estimation of
additional load as a factor of the existing load that may be drawn
before reaching the point of line maximum loadability of radial
distribution system (RDS) with different realistic load models at
different substation voltages. The proposed method involves a simple
line loadability index (LLI) that gives a measure of the proximity of
the present state of a line in the distribution system. The LLI can use
to assess voltage instability and the line loading margin. The
proposed method also compares with the existing method of
maximum loadability index [10]. The simulation results show that the
LLI can identify not only the weakest line/branch causing system
instability but also the system voltage collapse point when it is near
one. This feature enables us to set an index threshold to monitor and
predict system stability on-line so that a proper action can be taken to
prevent the system from collapse. To demonstrate the validity of the
proposed algorithm, computer simulations are carried out on two bus
and 69 bus RDS.
Abstract: Along with the progress of our information society,
various risks are becoming increasingly common, causing multiple social problems. For this reason, risk communications for
establishing consensus among stakeholders who have different
priorities have become important. However, it is not always easy for the decision makers to agree on measures to reduce risks based on
opposing concepts, such as security, privacy and cost. Therefore, we previously developed and proposed the “Multiple Risk Communicator" (MRC) with the following functions: (1) modeling
the support role of the risk specialist, (2) an optimization engine, and (3) displaying the computed results. In this paper, MRC program
version 1.0 is applied to the personal information leakage problem. The application process and validation of the results are discussed.
Abstract: In this study, the effect of mechanical activation on the synthesis of Fe3Al/Al2O3 nanocomposite has been investigated by using mechanochemical method. For this purpose, Aluminum powder and hematite as precursors, with stoichiometric ratio, have been utilized and other effective parameters in milling process were kept constant. Phase formation analysis, crystallite size measurement and lattice strain were studied by X-ray diffraction (XRD) by using Williamson-Hall method as well as microstructure and morphology were explored by Scanning electron microscopy (SEM). Also, Energy-dispersive X-ray spectroscopy (EDX) analysis was used in order to probe the particle distribution. The results showed that after 30-hour milling, the reaction was started, combustibly done and completed.
Abstract: Due to the tremendous amount of information provided
by the World Wide Web (WWW) developing methods for mining
the structure of web-based documents is of considerable interest. In
this paper we present a similarity measure for graphs representing
web-based hypertext structures. Our similarity measure is mainly
based on a novel representation of a graph as linear integer strings,
whose components represent structural properties of the graph. The
similarity of two graphs is then defined as the optimal alignment of
the underlying property strings. In this paper we apply the well known
technique of sequence alignments for solving a novel and challenging
problem: Measuring the structural similarity of generalized trees.
In other words: We first transform our graphs considered as high
dimensional objects in linear structures. Then we derive similarity
values from the alignments of the property strings in order to
measure the structural similarity of generalized trees. Hence, we
transform a graph similarity problem to a string similarity problem for
developing a efficient graph similarity measure. We demonstrate that
our similarity measure captures important structural information by
applying it to two different test sets consisting of graphs representing
web-based document structures.