Abstract: Estimation of the magnitude and causes of poisoning
was the objective of the current study. A retrospective study of
medical records of all poisoning children admitted to Benghazi
Children Hospital in Libya from January 2008 up to December 2010.
Number of children admitted was 244; the age ranged from less than
one to 13 years old. Most of cases were admitted with mild symptom
and the majority of them were boys. Only few cases admitted to
intensive care unit and there was no mortality recorded through the
period of study. Age group 1 to 3 years (50.8%) had the highest
frequency of admission and the peak of admission was during
summer. The most common cause of admission was due to ingestion
of medication (53.69%), House hold product exposure (26.64%) was
the second causes of admission while, 19.67% of admissions were
due to Food poisoning. Almost all admitted cases were accidental and
medicines were the most consumed substances in addition, improper
storage of toxic agents were the first risk factor of poisoning. Present
results indicated that, children poisoning seems to be a common
pediatric care problem which need to control and prevent.
Abstract: Mammalian genomes contain large number of
retroelements (SINEs, LINEs and LTRs) which could affect
expression of protein coding genes through associated transcription
factor binding sites (TFBS). Activity of the retroelement-associated
TFBS in many genes is confirmed experimentally but their global
functional impact remains unclear. Human SINEs (Alu repeats) and
mouse SINEs (B1 and B2 repeats) are known to be clustered in GCrich
gene rich genome segments consistent with the view that they
can contribute to regulation of gene expression. We have shown
earlier that Alu are involved in formation of cis-regulatory modules
(clusters of TFBS) in human promoters, and other authors reported
that Alu located near promoter CpG islands have an increased
frequency of CpG dinucleotides suggesting that these Alu are
undermethylated. Human Alu and mouse B1/B2 elements have an
internal bipartite promoter for RNA polymerase III containing
conserved sequence motif called B-box which can bind basal
transcription complex TFIIIC. It has been recently shown that TFIIIC
binding to B-box leads to formation of a boundary which limits
spread of repressive chromatin modifications in S. pombe. SINEassociated
B-boxes may have similar function but conservation of
TFIIIC binding sites in SINEs located near mammalian promoters
has not been studied earlier. Here we analysed abundance and
distribution of retroelements (SINEs, LINEs and LTRs) in annotated
sequences of the Database of mammalian transcription start sites
(DBTSS). Fractions of SINEs in human and mouse promoters are
slightly lower than in all genome but >40% of human and mouse
promoters contain Alu or B1/B2 elements within -1000 to +200 bp
interval relative to transcription start site (TSS). Most of these SINEs
is associated with distal segments of promoters (-1000 to -200 bp
relative to TSS) indicating that their insertion at distances >200 bp
upstream of TSS is tolerated during evolution. Distribution of SINEs
in promoters correlates negatively with the distribution of CpG
sequences. Using analysis of abundance of 12-mer motifs from the
B1 and Alu consensus sequences in genome and DBTSS it has been
confirmed that some subsegments of Alu and B1 elements are poorly
conserved which depends in part on the presence of CpG
dinucleotides. One of these CpG-containing subsegments in B1
elements overlaps with SINE-associated B-box and it shows better
conservation in DBTSS compared to genomic sequences. It has been
also studied conservation in DBTSS and genome of the B-box
containing segments of old (AluJ, AluS) and young (AluY) Alu
repeats and found that CpG sequence of the B-box of old Alu is
better conserved in DBTSS than in genome. This indicates that Bbox-
associated CpGs in promoters are better protected from
methylation and mutation than B-box-associated CpGs in genomic
SINEs. These results are consistent with the view that potential
TFIIIC binding motifs in SINEs associated with human and mouse
promoters may be functionally important. These motifs may protect
promoters from repressive histone modifications which spread from
adjacent sequences. This can potentially explain well known
clustering of SINEs in GC-rich gene rich genome compartments and
existence of unmethylated CpG islands.
Abstract: The present paper deals with the most adopted technical
solutions for the enhancement of the lift force of a wing. In fact,
during several flight conditions (such as take off and landing), the
lift force needs to be dramatically enhanced. Both trailing edge
devices (such as flaps) and leading edge ones (such as slats) are
described. Finally, the most advanced aerodynamic solutions to avoid
the separation of the boundary layer from aircraft wings at high angles
of attack are reviewed.
Abstract: Due to its geographical location, Iran is considered one of the earthquake-prone areas where the best way to decrease earthquake effects is supposed to be strengthening the buildings. Even though, one idea suggests that the use of adobe in constructing buildings be prohibited for its weak function especially in earthquake-prone areas, however, regarding ecological considerations, sustainability and other local skills, another idea pays special attention to adobe as one of the construction technologies which is popular among people. From the architectural and technological point of view, as strong sustainable building construction materials, compressed adobe construction materials make most of the construction in urban or rural areas ranging from small to big industrial buildings used to replace common earth blocks in traditional systems and strengthen traditional adobe buildings especially against earthquake. Mentioning efficient construction using compressed adobe system as a reliable replacement for traditional soil construction materials , this article focuses on the experiences of India in the fields of sustainable development of compressed adobe systems in the form of system in which the compressed soil is combined with cement, load bearing building with brick/solid concrete block system, brick system using rat trap bond, metal system with adobe infill and finally emphasizes on the use of these systems in the earthquake-struck city of Bam in Iran.
Abstract: A retrospective study was undertaken to record the
occurrence and pattern of fractures in small animals (dogs and cats)
from year 2005 to 2010. A total of 650 cases were presented in small
animal surgery unit out of which of 116 (dogs and cats) were
presented with history of fractures of different bones. A total of
17.8% (116/650) cases were of fractures which constituted dogs 67%
while cats were 23%. The majority of animals were intact. Trauma in
the form of road side accident was the principal cause of fractures in
dogs whereas as in cats it was fall from height. The ages of the
fractured dog ranged from 4 months to 12 years whereas in cat it was
from 4 weeks to 10 years. The femoral fractures represented 37.5%
and 25% respectively in dogs and cats. Diaphysis, distal metaphyseal
and supracondylar fractures were the most affected sites in dog and
cats. Tibial fracture in dogs and cats represented 21.5% and 10%
while humoral fractures were 7.9% and 14% in dogs and cats
respectively. Humoral condyler fractures were most commonly seen
in puppies aged 4 to 6 months. Fractured radius-ulna incidence was
19% and 14% in dogs and cats respectively. Other fractures recorded
were of lumbar vertebrae, mandible and metacarpals etc. The
management comprised of external and internal fixation in both the
species. The most common internal fixation technique employed was
Intramedullary fixation in long followed by other methods like stack
or cross pinning, wiring etc as per findings in the cases. The cast
bandage was used majorly as mean for external coaptation. The
paper discusses the outcome of the case as per the technique
employed.
Abstract: Cylindrical concrete reservoirs are appropriate choice
for storing liquids as water, oil and etc. By using of the pre-cast
concrete reservoirs instead of the in-situ constructed reservoirs, the
speed and precision of the construction would considerably increase.
In this construction method, wall and roof panels would make in
factory with high quality materials and precise controlling. Then,
pre-cast wall and roof panels would carry out to the construction site
for assembling. This method has a few faults such as: the existing
weeks in connection of wall panels together and wall panels to
foundation. Therefore, these have to be resisted under applied loads
such as seismic load. One of the innovative methods which was
successfully applied for seismic retrofitting of numerous pre-cast
cylindrical water reservoirs in New Zealand, using of the high tensile
cables around the reservoirs and post-tensioning them. In this paper,
analytical modeling of wall and roof panels and post-tensioned
cables are carried out with finite element method and the effect of
height to diameter ratio, post-tensioning force value, liquid level in
reservoir, installing position of tendons on seismic response of
reservoirs are investigated.
Abstract: This paper presents a pulse doubling technique in a 12-pulse ac-dc converter which supplies direct torque controlled motor drives (DTCIMD-s) in order to have better power quality conditions at the point of common coupling. The proposed technique increases the number of rectification pulses without significant changes in the installations and yields in harmonic reduction in both ac and dc sides. The 12-pulse rectified output voltage is accomplished via two paralleled six-pulse ac-dc converters each of them consisting of three-phase diode bridge rectifier. An autotransformer is designed to supply the rectifiers. The design procedure of magnetics is in a way such that makes it suitable for retrofit applications where a six-pulse diode bridge rectifier is being utilized. Independent operation of paralleled diode-bridge rectifiers, i.e. dc-ripple re-injection methodology, requires a Zero Sequence Blocking Transformer (ZSBT). Finally, a tapped interphase reactor is connected at the output of ZSBT to double the pulse numbers of output voltage up to 24 pulses. The aforementioned structure improves power quality criteria at ac mains and makes them consistent with the IEEE-519 standard requirements for varying loads. Furthermore, near unity power factor is obtained for a wide range of DTCIMD operation. A comparison is made between 6- pulse, 12-pulse, and proposed converters from view point of power quality indices. Results show that input current total harmonic distortion (THD) is less than 5% for the proposed topology at various loads.
Abstract: Nosocomial (i.e., hospital-acquired) infections
(NI) is a major cause of morbidity and mortality in hospitals. NI
rate is higher in intensive care units (ICU) than in the general
ward due to patients with severe symptoms, poor immunity,
and accepted many invasive therapies. Contact behaviors
between health caregivers and patients is one of the infect
factors. It is difficult to obtain complete contact records by
traditional method of retrospective analysis of medical records.
This paper establishes a contact history inferential model
(CHIM) intended to extend the use of Proximity Sensing of
rapid frequency identification (RFID) technology to
transferring all proximity events between health caregivers and
patients into clinical events (close-in events, contact events and
invasive events).The results of the study indicated that the
CHIM can infer proximity care activities into close-in events
and contact events.
The infection control team could redesign and build optimal
workflow in the ICU according to the patient-specific contact
history which provided by our automatic tracing system.
Abstract: This study retrospectively investigated the significance of whole body CT (WCT) for patients with sepsis. A medical chart review was retrospectively performed for all patients with systemic inflammatory response syndrome that were treated initially between April 2011 and March 2012. The subjects were divided into a WCT group that underwent WCT on arrival and a control group. Results of this study suggested that WCT for sepsis was useful for elderly patients whose chief complaint or physiological findings could not suggest the anatomical site of infection, to determine the infectious focus and indications/method for surgery, to diagnose the basic diseases associated with opportunistic infections and to evaluate complicated diseases
Abstract: The aim of this retrospective study was to evaluate the
parameters of dental implants such as patient gender, number of
implant, failed implant before prosthetic restorations and failed
implant after implantation and failed implant after prosthetic
restorations. 135 male and 99 female patients, total 234 implant
patients which have been treated with 450 implant between 2005-
2009 years in GATA Haydarpasa Training Hospital Dental Service.
Twelve implants were failed before prosthetic restorations. Four
implant were failed after fixed prosthetic restorations. Cumulative
survival rate after prostheses were 97.56 % during 6 years period.
Abstract: Background: Blunt aortic trauma (BAT) includes
various morphological changes that occur during deceleration,
acceleration and/or body compression in traffic accidents. The
various forms of BAT, from limited laceration of the intima to
complete transection of the aorta, depends on the force acting on the
vessel wall and the tolerance of the aorta to injury. The force depends
on the change in velocity, the dynamics of the accident and of the
seating position in the car. Tolerance to aortic injury depends on the
anatomy, histological structure and pathomorphological alterations
due to aging or disease of the aortic wall.
An overview of the literature and medical documentation reveals
that different terms are used to describe certain forms of BAT, which
can lead to misinterpretation of findings or diagnoses. We therefore,
propose a classification that would enable uniform systematic
screening of all forms of BAT. We have classified BAT into three
morphologycal types: TYPE I (intramural), TYPE II (transmural) and
TYPE III (multiple) aortic ruptures with appropriate subtypes.
Methods: All car accident casualties examined at the Institute of
Forensic Medicine from 2001 to 2009 were included in this
retrospective study. Autopsy reports were used to determine the
occurrence of each morphological type of BAT in deceased drivers,
front seat passengers and other passengers in cars and to define the
morphology of BAT in relation to the accident dynamics and the age
of the fatalities.
Results: A total of 391 fatalities in car accidents were included in
the study. TYPE I, TYPE II and TYPE III BAT were observed in
10,9%, 55,6% and 33,5%, respectively. The incidence of BAT in
drivers, front seat and other passengers was 36,7%, 43,1% and
28,6%, respectively. In frontal collisions, the incidence of BAT was
32,7%, in lateral collisions 54,2%, and in other traffic accidents
29,3%. The average age of fatalities with BAT was 42,8 years and of
those without BAT 39,1 years.
Conclusion: Identification and early recognition of the risk factors
of BAT following a traffic accident is crucial for successful treatment
of patients with BAT. Front seat passengers over 50 years of age who
have been injured in a lateral collision are the most at risk of BAT.
Abstract: The seismic rehabilitation designs of two reinforced
concrete school buildings, representative of a wide stock of similar
edifices designed under earlier editions of the Italian Technical
Standards, are presented in this paper. The mutual retrofit solution
elaborated for the two buildings consists in the incorporation of a
dissipative bracing system including pressurized fluid viscous springdampers
as passive protective devices. The mechanical parameters,
layouts and locations selected for the constituting elements of the
system; the architectural renovation projects developed to properly
incorporate the structural interventions and improve the appearance
of the buildings; highlights of the installation works already
completed in one of the two structures; and a synthesis of the
performance assessment analyses carried out in original and
rehabilitated conditions, are illustrated. The results of the analyses
show a remarkable enhancement of the seismic response capacities of
both structures. This allows reaching the high performance objectives
postulated in the retrofit designs with much lower costs and
architectural intrusion as compared to traditional rehabilitation
interventions designed for the same objectives.
Abstract: The aim of this study was to investigate the pregnancy
outcomes of teenage mothers at DanKhunThot hospital, Nakhon
Ratchasima, Thailand. A retrospective descriptive study was
conducted in 573 of teenage pregnant from charts reviewed from 1st
October 2010-31st March, 2012. Data were analyzed by frequency
distribution, mean and Standard Deviation.
The results shown several problems and negatives outcomes of
pregnancy in teenager such as not attended prenatal care, Low birth
weight infants, death fetus in utero and other complications. The
results of this study can be utilized in the development of prenatal,
perinatal and post natal care services, especially in DanKhunthot
Hospital contexts. Moreover, the results were present to the District
Health Care committees in order to enhance health care service
system for teenage pregnancy of DanKhunthot District in further.
Abstract: Road signs are the elements of roads with a lot of
influence in driver-s behavior. So that signals can fulfill its function,
they must overcome visibility and durability requirements,
particularly needed at night, when the coefficient of retroreflection
becomes a decisive factor in ensuring road safety. Accepting that the
visibility of the signage has implications for people-s safety, we
understand the importance to fulfill its function: to foster the highest
standards of service and safety in drivers. The usual conditions of
perception of any sign are determined by: age of the driver, reflective
material, luminosity, vehicle speed and emplacement. In this way,
this paper evaluates the different signals to increase the safety road.
Abstract: Temperature, relative humidity and overhygroscopic
moisture fields in a sandstone wall provided with interior thermal
insulation were calculated in order to assess the hygric performance
of the retrofitted wall. Computational simulations showed that during
the time period of 10 years which was subject of investigation no
overhygroscopic moisture appeared in the analyzed building
envelope so that it performed in a satisfactory way from the hygric
point of view.
Abstract: The primary objective of this research is to improve the flexural capacity of FRP strengthened RC Beam structures with Aluminum and Titanium laminates. FRP rupture of flexural strengthened RC beams using FRP plates generally occurs at the interface between FRP plate and the beam. Therefore, in order to prevent brittle rupture and improve the ductility of the system, this research was performed by using Aluminum and Titanium materials between the two different structural systems. The research also aims to provide various strengthening/retrofitting methods for RC beam structures and to conduct a preliminary analysis of the demands on the structural systems. This was achieved by estimation using the experimental data from this research to identify a flexural capacity for the systems. Ultimately, the preliminary analysis of current study showed that the flexural capacity and system demand ductility was significantly improved by the systems inserted with Aluminum and Titanium anchor plates. Further verification of the experimental research is currently on its way to develop a new or reliable design guideline to retrofit/strengthen the concrete-FRP structural system can be evaluated.
Abstract: Aurein 1.2 is a 13-residue amphipathic peptide with antibacterial and anticancer activity. Aurein1.2 and its retro analog were synthesized to study the activity of the peptides in relation to their structure. The antibacterial test result showed the retro-analog is inactive. The secondary structural analysis by CD spectra indicated that both of the peptides at TFE/Water adopt alpha-helical conformation. MD simulation was performed on aurein 1.2 and retro-analog in water and TFE in order to analyse the factors that are involved in the activity difference between retro and the native peptide. The simulation results are discussed and validated in the light of experimental data from the CD experiment. Both of the peptides showed a relatively similar pattern for their hydrophobicity, hydrophilicity, solvent accessible surfaces, and solvent accessible hydrophobic surfaces. However, they showed different in directions of dipole moment of peptides. Also, Our results further indicate that the reversion of the amino acid sequence affects flexibility .The data also showed that factors causing structural rigidity may decrease the activity. Consequently, our finding suggests that in the case of sequence-reversed peptide strategy, one has to pay attention to the role of amino acid sequence order in making flexibility and role of dipole moment direction in peptide activity. KeywordsAntimicrobial peptides, retro, molecular dynamic, circular dichroism.
Abstract: The unanticipated brittle fracture of connection of the
steel moment resisting frame (SMRF) occurred in 1994 the Northridge
earthquake. Since then, the researches for the vulnerability of
connection of the existing SMRF and for rehabilitation of those
buildings were conducted. This paper suggests performance-based
optimal seismic retrofit technique using connection upgrade. For
optimal design, a multi-objective genetic algorithm(NSGA-II) is used.
One of the two objective functions is to minimize initial cost and
another objective function is to minimize lifetime seismic damages
cost. The optimal algorithm proposed in this paper is performed
satisfying specified performance objective based on FEMA 356. The
nonlinear static analysis is performed for structural seismic
performance evaluation. A numerical example of SAC benchmark
SMRF is provided using the performance-based optimal seismic
retrofit technique proposed in this paper
Abstract: Participation in sporting activities can lead to injury.
Sport injuries have been widely studied in many sports including the
more extreme categories of aquatic board sports. Kitesurfing is a
relatively new water surface action sport, and has not yet been
widely studied in terms of injuries and stress on the body. The aim of
this study was to get information about which injuries that are most
common among kitesurfing participants, where they occur, and their
causes. Injuries were studied using an international open web
questionnaire (n=206).
The results showed that many respondents reported injuries, in
total 251 injuries to knee (24%), ankle (17%), trunk (16%) and
shoulders (10%), often sustained while doing jumps and tricks
(40%). Among the reported injuries were joint injuries (n=101),
muscle/tendon damages (n=47), wounds and cuts (n=36) and bone
fractures (n=28). Also environmental factors and equipment can
influence the risk of injury, or the extent of injury in a hazardous
situation. Conclusively, the information from this retrospective study
supports earlier studies in terms of prevalence and site of injuries.
Suggestively, this information should be used for to build a
foundation of knowledge about the sport for development of
applications for physical training and product development.
Abstract: A novel low-cost impedance control structure is
proposed for monitoring the contact force between end-effector and
environment without installing an expensive force/torque sensor.
Theoretically, the end-effector contact force can be estimated from the
superposition of each joint control torque. There have a nonlinear
matrix mapping function between each joint motor control input and
end-effector actuating force/torques vector. This new force control
structure can be implemented based on this estimated mapping matrix.
First, the robot end-effector is manipulated to specified positions, then
the force controller is actuated based on the hall sensor current
feedback of each joint motor. The model-free fuzzy sliding mode
control (FSMC) strategy is employed to design the position and force
controllers, respectively. All the hardware circuits and software
control programs are designed on an Altera Nios II embedded
development kit to constitute an embedded system structure for a
retrofitted Mitsubishi 5 DOF robot. Experimental results show that PI
and FSMC force control algorithms can achieve reasonable contact
force monitoring objective based on this hardware control structure.