Abstract: In this paper we present a method for gene ranking
from DNA microarray data. More precisely, we calculate the correlation
networks, which are unweighted and undirected graphs, from
microarray data of cervical cancer whereas each network represents
a tissue of a certain tumor stage and each node in the network
represents a gene. From these networks we extract one tree for
each gene by a local decomposition of the correlation network. The
interpretation of a tree is that it represents the n-nearest neighbor
genes on the n-th level of a tree, measured by the Dijkstra distance,
and, hence, gives the local embedding of a gene within the correlation
network. For the obtained trees we measure the pairwise similarity
between trees rooted by the same gene from normal to cancerous
tissues. This evaluates the modification of the tree topology due to
progression of the tumor. Finally, we rank the obtained similarity
values from all tissue comparisons and select the top ranked genes.
For these genes the local neighborhood in the correlation networks
changes most between normal and cancerous tissues. As a result
we find that the top ranked genes are candidates suspected to be
involved in tumor growth and, hence, indicates that our method
captures essential information from the underlying DNA microarray
data of cervical cancer.
Abstract: Recently, as information industry and mobile
communication technology are developing, this study is conducted on
the new concept of intelligent structures and maintenance techniques
that applied wireless sensor network, USN (Ubiquitous Sensor
Network), to social infrastructures such as civil and architectural
structures on the basis of the concept of Ubiquitous Computing that
invisibly provides human life with computing, along with mutually
cooperating, compromising and connecting networks each other by
having computers within all objects around us.
Therefore, the purpose of this study is to investigate the capability
of wireless communication of sensor node embedded in reinforced
concrete structure with a basic experiment on an electric wave
permeability of sensor node by fabricating molding with variables of
concrete thickness and steel bars that are mostly used in constructing
structures to determine the feasibility of application to constructing
structures with USN.
At this time, with putting the pitches of steel bars, the thickness of
concrete placed, and the intensity of RF signal of a
transmitter-receiver as variables and when wireless communication
module was installed inside, the possible communication distance of
plain concrete and the possible communication distance by the pitches
of steel bars was measured in the horizontal and vertical direction
respectively. Besides, for the precise measurement of diminution of an
electric wave, the magnitude of an electric wave in the range of used
frequencies was measured by using Spectrum Analyzer. The
phenomenon of diminution of an electric wave was numerically
analyzed and the effect of the length of wavelength of frequencies was
analyzed by the properties of a frequency band area.
As a result of studying the feasibility of an application to
constructing structures with wireless sensor, in case of plain concrete,
it shows 45cm for the depth of permeability and in case of reinforced
concrete with the pitches of 5cm, it shows 37cm and 45cm for the
pitches of 15cm.
Abstract: We report on the development of a model to
understand why the range of experience with respect to HIV
infection is so diverse, especially with respect to the latency period.
To investigate this, an agent-based approach is used to extract highlevel
behaviour which cannot be described analytically from the set
of interaction rules at the cellular level. A network of independent
matrices mimics the chain of lymph nodes. Dealing with massively
multi-agent systems requires major computational effort. However,
parallelisation methods are a natural consequence and advantage of
the multi-agent approach and, using the MPI library, are here
implemented, tested and optimized. Our current focus is on the
various implementations of the data transfer across the network.
Three communications strategies are proposed and tested, showing
that the most efficient approach is communication based on the
natural lymph-network connectivity.
Abstract: In this paper, an efficient structural approach for
recognizing on-line handwritten digits is proposed. After reading
the digit from the user, the slope is estimated and normalized for
adjacent nodes. Based on the changing of signs of the slope values,
the primitives are identified and extracted. The names of these
primitives are represented by strings, and then a finite state
machine, which contains the grammars of the digits, is traced to
identify the digit. Finally, if there is any ambiguity, it will be
resolved. Experiments showed that this technique is flexible and
can achieve high recognition accuracy for the shapes of the digits
represented in this work.
Abstract: The increasing interest on processing data created by
sensor networks has evolved into approaches to implement sensor
networks as databases. The aggregation operator, which calculates a
value from a large group of data such as computing averages or sums,
etc. is an essential function that needs to be provided when
implementing such sensor network databases. This work proposes to
add the DURING clause into TinySQL to calculate values during a
specific long period and suggests a way to implement the aggregation
service in sensor networks by applying materialized view and
incremental view maintenance techniques that is used in data
warehouses. In sensor networks, data values are passed from child
nodes to parent nodes and an aggregation value is computed at the root
node. As such root nodes need to be memory efficient and low
powered, it becomes a problem to recompute aggregate values from all
past and current data. Therefore, applying incremental view
maintenance techniques can reduce the memory consumption and
support fast computation of aggregate values.
Abstract: Plasmodium vivax malaria differs from P. falciparum malaria in that a person suffering from P. vivax infection can suffer relapses of the disease. This is due the parasite being able to remain dormant in the liver of the patients where it is able to re-infect the patient after a passage of time. During this stage, the patient is classified as being in the dormant class. The model to describe the transmission of P. vivax malaria consists of a human population divided into four classes, the susceptible, the infected, the dormant and the recovered. The effect of a time delay on the transmission of this disease is studied. The time delay is the period in which the P. vivax parasite develops inside the mosquito (vector) before the vector becomes infectious (i.e., pass on the infection). We analyze our model by using standard dynamic modeling method. Two stable equilibrium states, a disease free state E0 and an endemic state E1, are found to be possible. It is found that the E0 state is stable when a newly defined basic reproduction number G is less than one. If G is greater than one the endemic state E1 is stable. The conditions for the endemic equilibrium state E1 to be a stable spiral node are established. For realistic values of the parameters in the model, it is found that solutions in phase space are trajectories spiraling into the endemic state. It is shown that the limit cycle and chaotic behaviors can only be achieved with unrealistic parameter values.
Abstract: Artificial Neural Network (ANN) has been
extensively used for classification of heart sounds for its
discriminative training ability and easy implementation. However, it
suffers from overparameterization if the number of nodes is not
chosen properly. In such cases, when the dataset has redundancy
within it, ANN is trained along with this redundant information that
results in poor validation. Also a larger network means more
computational expense resulting more hardware and time related
cost. Therefore, an optimum design of neural network is needed
towards real-time detection of pathological patterns, if any from heart
sound signal. The aims of this work are to (i) select a set of input
features that are effective for identification of heart sound signals and
(ii) make certain optimum selection of nodes in the hidden layer for a
more effective ANN structure. Here, we present an optimization
technique that involves Singular Value Decomposition (SVD) and
QR factorization with column pivoting (QRcp) methodology to
optimize empirically chosen over-parameterized ANN structure.
Input nodes present in ANN structure is optimized by SVD followed
by QRcp while only SVD is required to prune undesirable hidden
nodes. The result is presented for classifying 12 common
pathological cases and normal heart sound.
Abstract: A wireless Ad-hoc network consists of wireless nodes
communicating without the need for a centralized administration, in
which all nodes potentially contribute to the routing process.In this
paper, we report the simulation results of four different scenarios for
wireless ad hoc networks having thirty nodes. The performances of
proposed networks are evaluated in terms of number of hops per
route, delay and throughput with the help of OPNET simulator.
Channel speed 1 Mbps and simulation time 600 sim-seconds were
taken for all scenarios. For the above analysis DSR routing protocols
has been used. The throughput obtained from the above analysis
(four scenario) are compared as shown in Figure 3. The average
media access delay at node_20 for two routes and at node_20 for four
different scenario are compared as shown in Figures 4 and 5. It is
observed that the throughput will degrade when it will follow
different hops for same source to destination (i.e. it has dropped from
1.55 Mbps to 1.43 Mbps which is around 9.7%, and then dropped to
0.48Mbps which is around 35%).
Abstract: This paper deals with efficient quadrature formulas involving functions that are observed only at fixed sampling points. The approach that we develop is derived from efficient continuous quadrature formulas, such as Gauss-Legendre or Clenshaw-Curtis quadrature. We select nodes at sampling positions that are as close as possible to those of the associated classical quadrature and we update quadrature weights accordingly. We supply the theoretical quadrature error formula for this new approach. We show on examples the potential gain of this approach.
Abstract: Fast delay estimation methods, as opposed to
simulation techniques, are needed for incremental performance
driven layout synthesis. On-chip inductive effects are becoming
predominant in deep submicron interconnects due to increasing clock
speed and circuit complexity. Inductance causes noise in signal
waveforms, which can adversely affect the performance of the circuit
and signal integrity. Several approaches have been put forward which
consider the inductance for on-chip interconnect modelling. But for
even much higher frequency, of the order of few GHz, the shunt
dielectric lossy component has become comparable to that of other
electrical parameters for high speed VLSI design. In order to cope up
with this effect, on-chip interconnect has to be modelled as
distributed RLCG line. Elmore delay based methods, although
efficient, cannot accurately estimate the delay for RLCG interconnect
line. In this paper, an accurate analytical delay model has been
derived, based on first and second moments of RLCG
interconnection lines. The proposed model considers both the effect
of inductance and conductance matrices. We have performed the
simulation in 0.18μm technology node and an error of as low as less
as 5% has been achieved with the proposed model when compared to
SPICE. The importance of the conductance matrices in interconnect
modelling has also been discussed and it is shown that if G is
neglected for interconnect line modelling, then it will result an delay
error of as high as 6% when compared to SPICE.
Abstract: The NGN (Next Generation Network), which can
provide advanced multimedia services over an all-IP based network, has been the subject of much attention for years. While there have
been tremendous efforts to develop its architecture and protocols, especially for IMS, which is a key technology of the NGN, it is far
from being widely deployed. However, efforts to create an advanced
signaling infrastructure realizing many requirements have resulted in a
large number of functional components and interactions between those
components. Thus, the carriers are trying to explore effective ways to
deploy IMS while offering value-added services. As one such
approach, we have proposed a self-organizing IMS. A self-organizing
IMS enables IMS functional components and corresponding physical
nodes to adapt dynamically and automatically based on situation such
as network load and available system resources while continuing IMS
operation. To realize this, service continuity for users is an important
requirement when a reconfiguration occurs during operation. In this
paper, we propose a mechanism that will provide service continuity to
users and focus on the implementation and describe performance
evaluation in terms of number of control signaling and processing time
during reconfiguration