Abstract: Medical image registration is the key technology in image guided radiation therapy (IGRT) systems. On the basis of the previous work on our IGRT prototype with a biorthogonal x-ray imaging system, we described a method focused on the 2D/2D rigid-body registration using multiresolution pyramid based mutual information in this paper. Three key steps were involved in the method ： firstly, four 2D images were obtained including two x-ray projection images and two digital reconstructed radiographies（DRRs ） as the input for the registration ； Secondly, each pair of the corresponding x-ray image and DRR image were matched using multiresolution pyramid based mutual information under the ITK registration framework ； Thirdly, we got the final couch offset through a coordinate transformation by calculating the translations acquired from the two pairs of the images. A simulation example of a parotid gland tumor case and a clinical example of an anthropomorphic head phantom were employed in the verification tests. In addition, the influence of different CT slice thickness were tested. The simulation results showed that the positioning errors were 0.068±0.070, 0.072±0.098, 0.154±0.176mm along three axes which were lateral, longitudinal and vertical. The clinical test indicated that the positioning errors of the planned isocenter were 0.066, 0.07, 2.06mm on average with a CT slice thickness of 2.5mm. It can be concluded that our method with its verified accuracy and robustness can be effectively used in IGRT systems for patient setup.
Abstract: Organ motion, especially respiratory motion, is a technical challenge to radiation therapy planning and dosimetry. This motion induces displacements and deformation of the organ tissues within the irradiated region which need to be taken into account when simulating dose distribution during treatment. Finite element modeling (FEM) can provide a great insight into the mechanical behavior of the organs, since they are based on the biomechanical material properties, complex geometry of organs, and anatomical boundary conditions. In this paper we present an original approach that offers the possibility to combine image-based biomechanical models with particle transport simulations. We propose a new method to map material density information issued from CT images to deformable tetrahedral meshes. Based on the principle of mass conservation our method can correlate density variation of organ tissues with geometrical deformations during the different phases of the respiratory cycle. The first results are particularly encouraging, as local error quantification of density mapping on organ geometry and density variation with organ motion are performed to evaluate and validate our approach.
Abstract: A real time image-guided electroplating system is
proposed in this paper. Unlike previous electroplating systems, instead
of using the intermittent mode to electroplate 500um long copper
specimen, a CCD camera and a motion controller are used to adjust
anode-cathode distance to obtain better results. Since the image of the
gap distance is highly deteriorated due to complex chemical-electrical
operation inside the electrolyte, to determine the gap distance, an
image processing algorithm is developed and mainly based on the
entropy and energy values. In addition, the color and incidence
direction of light source are also discussed to help the image process in
this paper. From the experiment results, the specimens created by the
proposed system show better structure, better uniformity and better
finishing surface compared to those by previous intermittent
electroplating setup.
Abstract: Camera calibration is an indispensable step for augmented
reality or image guided applications where quantitative information
should be derived from the images. Usually, a camera
calibration is obtained by taking images of a special calibration object
and extracting the image coordinates of projected calibration marks
enabling the calculation of the projection from the 3d world coordinates
to the 2d image coordinates. Thus such a procedure exhibits
typical steps, including feature point localization in the acquired
images, camera model fitting, correction of distortion introduced by
the optics and finally an optimization of the model-s parameters. In
this paper we propose to extend this list by further step concerning
the identification of the optimal subset of images yielding the smallest
overall calibration error. For this, we present a Monte Carlo based
algorithm along with a deterministic extension that automatically
determines the images yielding an optimal calibration. Finally, we
present results proving that the calibration can be significantly
improved by automated image selection.