Histopathological Changes in Liver and Muscle of Tilapia Fish from QIRE Exposed to Concentrations of Heavy Metals

Toxicity of copper (Cu), lead (Pb) and iron (Fe) to Tilapia guinensis was carried out for 4 days with a view to determining their effects on the liver and muscle tissues. Tilapia guinensis samples of about 10 - 14cm length and 0.2 – 0.4kg weight each were obtained from University of Calabar fish ponds and acclimated for three (3) days before the experimental set up. Survivors after the 96-hr LC50 test period were selected from test solutions of the heavy metals for the histopathological studies. Histological preparations of liver and muscle tissues were randomly examined for histopathological lesions. Results of the histological examinations showed gross abnormalities in the liver tissues due to pathological and degenerative changes compared to liver and muscle tissues from control samples (tilapia fishes from aquaria without heavy metals). Extensive hepatocyte necrosis with chronic inflammatory changes was observed in the liver of fishes exposed to Cu solution. Similar but less damaging effects were observed in the liver of fishes exposed to Pb and Fe. The extent of lesion observed was therefore heavy metal-related. However, no pathologic changes occurred in the muscle tissues.

Access to Higher Education in Nigeria: The University of Calabar Pre-Degree Program Experience

The pre-degree program of the University of Calabar was introduced to help increase access to tertiary Education in science related courses. Its main objective was to provide access to candidates from educationally less developed states (ELDS) and states within its catchment area. An impact evaluation of the program was conducted, from where the aspect of providing access to University Education was reported here. Two research questions were formulated; expost-facto research design and purposive sampling technique were adopted for the study. Data collected was analyzed using descriptive statistics in terms of frequencies and percentages. The result of data analysis showed that the pre-degree program of the University of Calabar has provided educational access to Nigerians especially those from educationally less developed states in science related courses. It was therefore recommended that the program be sustained and further be improved upon to facilitate its continued provision of access to University Education in Nigeria.