Abstract: The use of Inverse Discrete Fourier Transform (IDFT) implemented in the form of Inverse Fourier Transform (IFFT) is one of the standard method of reconstructing Magnetic Resonance Imaging (MRI) from uniformly sampled K-space data. In this tutorial, three of the major problems associated with the use of IFFT in MRI reconstruction are highlighted. The tutorial also gives brief introduction to MRI physics; MRI system from instrumentation point of view; K-space signal and the process of IDFT and IFFT for One and two dimensional (1D and 2D) data.
Abstract: Dynamic shear test on simulated phantom can be used
to validate magnetic resonance elastography (MRE) measurements.
Phantom gel has been usually utilized for the cell culture of cartilage
and soft tissue and also been used for mechanical property
characterization using imaging systems. The viscoelastic property of
the phantom would be important for dynamic experiments and
analyses. In this study, An axisymmetric FE model is presented for
determining the dynamic shear behaviour of brain simulated phantom
using ABAQUS. The main objective of this study was to investigate
the effect of excitation frequencies and boundary conditions on shear
modulus and shear viscosity in viscoelastic media.
Abstract: Visual attention allows user to select the most relevant
information to ongoing behaviour. This paper presents a study on; i)
the performance of people measurements, ii) accurateness of people
measurement of the peaks that correspond to chemical quantities
from the Magnetic Resonance Spectroscopy (MRS) graphs and iii)
affects of people measurements to the algorithm-based diagnosis.
Participant-s eye-movement was recorded using eye-tracker tool
(Eyelink II). This experiment involves three participants for
examining 20 MRS graphs to estimate the peaks of chemical
quantities which indicate the abnormalities associated with
Cerebellar Tumours (CT). The status of each MRS is verified by
using decision algorithm. Analysis involves determination of
humans-s eye movement pattern in measuring the peak of
spectrograms, scan path and determining the relationship of
distributions of fixation durations with the accuracy of measurement.
In particular, the eye-tracking data revealed which aspects of the
spectrogram received more visual attention and in what order they
were viewed. This preliminary investigation provides a proof of
concept for use of the eye tracking technology as the basis for
expanded CT diagnosis.
Abstract: The proper design of RF pulses in magnetic resonance imaging (MRI) has a direct impact on the quality of acquired images, and is needed for many applications. Several techniques have been proposed to obtain the RF pulse envelope given the desired slice profile. Unfortunately, these techniques do not take into account the limitations of practical implementation such as limited amplitude resolution. Moreover, implementing constraints for special RF pulses on most techniques is not possible. In this work, we propose to develop an approach for designing optimal RF pulses under theoretically any constraints. The new technique will pose the RF pulse design problem as a combinatorial optimization problem and uses efficient techniques from this area such as genetic algorithms (GA) to solve this problem. In particular, an objective function will be proposed as the norm of the difference between the desired profile and the one obtained from solving the Bloch equations for the current RF pulse design values. The proposed approach will be verified using analytical solution based RF simulations and compared to previous methods such as Shinnar-Le Roux (SLR) method, and analysis, selected, and tested the options and parameters that control the Genetic Algorithm (GA) can significantly affect its performance to get the best improved results and compared to previous works in this field. The results show a significant improvement over conventional design techniques, select the best options and parameters for GA to get most improvement over the previous works, and suggest the practicality of using of the new technique for most important applications as slice selection for large flip angles, in the area of unconventional spatial encoding, and another clinical use.
Abstract: Medical image modalities such as computed
tomography (CT), magnetic resonance imaging (MRI), ultrasound
(US), X-ray are adapted to diagnose disease. These modalities
provide flexible means of reviewing anatomical cross-sections and
physiological state in different parts of the human body. The raw
medical images have a huge file size and need large storage
requirements. So it should be such a way to reduce the size of those
image files to be valid for telemedicine applications. Thus the image
compression is a key factor to reduce the bit rate for transmission or
storage while maintaining an acceptable reproduction quality, but it is
natural to rise the question of how much an image can be compressed
and still preserve sufficient information for a given clinical
application. Many techniques for achieving data compression have
been introduced. In this study, three different MRI modalities which
are Brain, Spine and Knee have been compressed and reconstructed
using wavelet transform. Subjective and objective evaluation has
been done to investigate the clinical information quality of the
compressed images. For the objective evaluation, the results show
that the PSNR which indicates the quality of the reconstructed image
is ranging from (21.95 dB to 30.80 dB, 27.25 dB to 35.75 dB, and
26.93 dB to 34.93 dB) for Brain, Spine, and Knee respectively. For
the subjective evaluation test, the results show that the compression
ratio of 40:1 was acceptable for brain image, whereas for spine and
knee images 50:1 was acceptable.
Abstract: The acoustic and articulatory properties of fricative speech sounds are being studied using magnetic resonance imaging (MRI) and acoustic recordings from a single subject. Area functions were derived from a complete set of axial and coronal MR slices using two different methods: the Mermelstein technique and the Blum transform. Area functions derived from the two techniques were shown to differ significantly in some cases. Such differences will lead to different acoustic predictions and it is important to know which is the more accurate. The vocal tract acoustic transfer function (VTTF) was derived from these area functions for each fricative and compared with measured speech signals for the same fricative and same subject. The VTTFs for /f/ in two vowel contexts and the corresponding acoustic spectra are derived here; the Blum transform appears to show a better match between prediction and measurement than the Mermelstein technique.
Abstract: Segmenting the lungs in medical images is a
challenging and important task for many applications. In particular,
automatic segmentation of lung cavities from multiple magnetic
resonance (MR) images is very useful for oncological applications
such as radiotherapy treatment planning. However, distinguishing of
the lung areas is not trivial due to largely changing lung shapes, low
contrast and poorly defined boundaries. In this paper, we address
lung segmentation problem from pulmonary magnetic resonance
images and propose an automated method based on a robust regionaided
geometric snake with a modified diffused region force into the
standard geometric model definition. The extra region force gives the
snake a global complementary view of the lung boundary
information within the image which along with the local gradient
flow, helps detect fuzzy boundaries. The proposed method has been
successful in segmenting the lungs in every slice of 30 magnetic
resonance images with 80 consecutive slices in each image. We
present results by comparing our automatic method to manually
segmented lung cavities provided by an expert radiologist and with
those of previous works, showing encouraging results and high
robustness of our approach.
Abstract: Presence of phytosterol compound in Durian seed
(Durio zibethinus) or known as King of fruits has been discovered
from screening work using reagent test. Further analysis work has
been carried out using mass spectrometer in order to support the
priliminary finding. Isolation and purification of the major
phytosterol has been carried out using an open column
chromatography. The separation was monitored using thin layer
chromatography (TLC). Major isolated compounds and purified
phytosterol were identified using mass spectrometer and nuclear
magnetic resonance (NMR). This novel finding could promote
utilization of durian seeds as a functional ingredient in food products
through production of standardized extract based on phytosterol
content.
Abstract: Segmentation of Magnetic Resonance Imaging (MRI) images is the most challenging problems in medical imaging. This paper compares the performances of Seed-Based Region Growing (SBRG), Adaptive Network-Based Fuzzy Inference System (ANFIS) and Fuzzy c-Means (FCM) in brain abnormalities segmentation. Controlled experimental data is used, which designed in such a way that prior knowledge of the size of the abnormalities are known. This is done by cutting various sizes of abnormalities and pasting it onto normal brain tissues. The normal tissues or the background are divided into three different categories. The segmentation is done with fifty seven data of each category. The knowledge of the size of the abnormalities by the number of pixels are then compared with segmentation results of three techniques proposed. It was proven that the ANFIS returns the best segmentation performances in light abnormalities, whereas the SBRG on the other hand performed well in dark abnormalities segmentation.
Abstract: This paper presents a technique for diagnosis of the abdominal aorta aneurysm in magnetic resonance imaging (MRI) images. First, our technique is designed to segment the aorta image in MRI images. This is a required step to determine the volume of aorta image which is the important step for diagnosis of the abdominal aorta aneurysm. Our proposed technique can detect the volume of aorta in MRI images using a new external energy for snakes model. The new external energy for snakes model is calculated from Law-s texture. The new external energy can increase the capture range of snakes model efficiently more than the old external energy of snakes models. Second, our technique is designed to diagnose the abdominal aorta aneurysm by Bayesian classifier which is classification models based on statistical theory. The feature for data classification of abdominal aorta aneurysm was derived from the contour of aorta images which was a result from segmenting of our snakes model, i.e., area, perimeter and compactness. We also compare the proposed technique with the traditional snakes model. In our experiment results, 30 images are trained, 20 images are tested and compared with expert opinion. The experimental results show that our technique is able to provide more accurate results than 95%.
Abstract: An alternative approach to the use of Discrete Fourier
Transform (DFT) for Magnetic Resonance Imaging (MRI) reconstruction
is the use of parametric modeling technique. This method
is suitable for problems in which the image can be modeled by
explicit known source functions with a few adjustable parameters.
Despite the success reported in the use of modeling technique as an
alternative MRI reconstruction technique, two important problems
constitutes challenges to the applicability of this method, these are
estimation of Model order and model coefficient determination. In
this paper, five of the suggested method of evaluating the model
order have been evaluated, these are: The Final Prediction Error
(FPE), Akaike Information Criterion (AIC), Residual Variance (RV),
Minimum Description Length (MDL) and Hannan and Quinn (HNQ)
criterion. These criteria were evaluated on MRI data sets based on the
method of Transient Error Reconstruction Algorithm (TERA). The
result for each criterion is compared to result obtained by the use of a
fixed order technique and three measures of similarity were evaluated.
Result obtained shows that the use of MDL gives the highest measure
of similarity to that use by a fixed order technique.
Abstract: The first and basic cause of the failure of concrete is repeated freezing (thawing) of moisture contained in the pores, microcracks, and cavities of the concrete. On transition to ice, water existing in the free state in cracks increases in volume, expanding the recess in which freezing occurs. A reduction in strength below the initial value is to be expected and further cycle of freezing and thawing have a further marked effect. By using some experimental parameters like nuclear magnetic resonance variation (NMR), enthalpy-temperature (or heat capacity) variation, we can resolve between the various water states and their effect on concrete properties during cooling through the freezing transition temperature range. The main objective of this paper is to describe the principal type of water responsible for the reduction in strength and structural damage (frost damage) of concrete following repeated freeze –thaw cycles. Some experimental work was carried out at the institute of cryogenics to determine what happens to water in concrete during the freezing transition.
Abstract: The characterization of κ-carrageenan could provide a
better understanding of its functions in biological, medical and
industrial applications. Chemical and physical analyses of
carrageenan from seaweeds, Euchema cottonii L., were done to offer
information on its properties and the effects of Co-60 γ-irradiation on
its thermochemical characteristics. The structural and morphological
characteristics of κ-carrageenan were determined using scanning
electron microscopy (SEM) while the composition, molecular weight
and thermal properties were determined using attenuated total
reflectance Fourier transform infrared spectroscopy (ATR-FTIR), gel
permeation chromatography (GPC), thermal gravimetric analysis
(TGA) and differential scanning calorimetry (DSC). Further chemical
analysis was done using hydrogen-1 nuclear magnetic resonance (1H
NMR) and functional characteristics in terms of biocompatibility
were evaluated using cytotoxicity test.
Abstract: An important problem in speech research is the automatic extraction of information about the shape and dimensions of the vocal tract during real-time speech production. We have previously developed Southampton dynamic magnetic resonance imaging (SDMRI) as an approach to the solution of this problem.However, the SDMRI images are very noisy so that shape extraction is a major challenge. In this paper, we address the problem of tongue shape extraction, which poses difficulties because this is a highly deforming non-parametric shape. We show that combining active shape models with the dynamic Hough transform allows the tongue shape to be reliably tracked in the image sequence.
Abstract: Magnetic Resonance Imaging play a vital role in the decision-diagnosis process of brain MR images. For an accurate diagnosis of brain related problems, the experts mostly compares both T1 and T2 weighted images as the information presented in these two images are complementary. In this paper, rotational and translational invariant form of Local binary Pattern (LBP) with additional gray scale information is used to retrieve similar slices of T1 weighted images from T2 weighted images or vice versa. The incorporation of additional gray scale information on LBP can extract more local texture information. The accuracy of retrieval can be improved by extracting moment features of LBP and reweighting the features based on users feedback. Here retrieval is done in a single subject scenario where similar images of a particular subject at a particular level are retrieved, and multiple subjects scenario where relevant images at a particular level across the subjects are retrieved.
Abstract: This paper describes an automatic algorithm to restore
the shape of three-dimensional (3D) left ventricle (LV) models created
from magnetic resonance imaging (MRI) data using a geometry-driven
optimization approach. Our basic premise is to restore the LV shape
such that the LV epicardial surface is smooth after the restoration. A
geometrical measure known as the Minimum Principle Curvature (κ2)
is used to assess the smoothness of the LV. This measure is used to
construct the objective function of a two-step optimization process.
The objective of the optimization is to achieve a smooth epicardial
shape by iterative in-plane translation of the MRI slices.
Quantitatively, this yields a minimum sum in terms of the magnitude
of κ
2, when κ2 is negative. A limited memory quasi-Newton algorithm,
L-BFGS-B, is used to solve the optimization problem. We tested our
algorithm on an in vitro theoretical LV model and 10 in vivo
patient-specific models which contain significant motion artifacts. The
results show that our method is able to automatically restore the shape
of LV models back to smoothness without altering the general shape of
the model. The magnitudes of in-plane translations are also consistent
with existing registration techniques and experimental findings.
Abstract: Dynamic Causal Modeling (DCM) functional
Magnetic Resonance Imaging (fMRI) is a promising technique to
study the connectivity among brain regions and effects of stimuli
through modeling neuronal interactions from time-series
neuroimaging. The aim of this study is to study characteristics of a
mirror neuron system (MNS) in elderly group (age: 60-70 years old).
Twenty volunteers were MRI scanned with visual stimuli to study a
functional brain network. DCM was employed to determine the
mechanism of mirror neuron effects. The results revealed major
activated areas including precentral gyrus, inferior parietal lobule,
inferior occipital gyrus, and supplementary motor area. When visual
stimuli were presented, the feed-forward connectivity from visual
area to conjunction area was increased and forwarded to motor area.
Moreover, the connectivity from the conjunction areas to premotor
area was also increased. Such findings can be useful for future
diagnostic process for elderly with diseases such as Parkinson-s and
Alzheimer-s.
Abstract: Iron oxide nanoparticle was synthesized by reactive-precipitation method followed by high speed centrifuge and phase transfer in order to stabilized nanoparticles in the solvent. Particle size of SPIO was 8.2 nm by SEM, and the hydraulic radius was 17.5 nm by dynamic light scattering method. Coercivity and saturated magnetism were determined by VSM (vibrating sample magnetometer), coercivity of nanoparticle was lower than 10 Hc, and the saturated magnetism was higher than 65 emu/g. Stabilized SPIO was then transferred to aqueous phase by reacted with excess amount of poly (ethylene glycol) (PEG) silane. After filtration and dialysis, the SPIO T2 contrast agent was ready to use. The hydraulic radius of final product was about 70~100 nm, the relaxation rates R2 (1/T2) measured by magnetic resonance imaging (MRI) was larger than 200(sec-1).
Abstract: A four element prototype phased array surface probe
has been designed and constructed to improve clinical human
prostate spectroscopic data. The probe consists of two pairs of
adjacent rectangular coils with an optimum overlap to reduce the
mutual inductance. The two pairs are positioned on the anterior and
the posterior pelvic region and two couples of varactors at the input
of each coil undertake the procedures of tuning and matching. The
probe switches off and on automatically during the consecutive
phases of the MR experiment with the use of an analog switch that is
triggered by a microcontroller. Experimental tests that were carried
out resulted in high levels of tuning accuracy. Also, the switching
mechanism functions properly for various applied loads and pulse
sequence characteristics, producing only 10 μs of latency.
Abstract: A model of (4, 4) single-walled boron-nitride nanotube as a representative of armchair boron-nitride nanotubes studied. At first the structure optimization performed and then Nuclear Magnetic Resonance parameters (NMR) by Density Functional Theory (DFT) method at 11B and 15N nuclei calculated. Resulted parameters evaluation presents electrostatic environment heterogeneity along the nanotube and especially at the ends but the nuclei in a layer feel the same electrostatic environment. All of calculations carried out using Gaussian 98 Software package.