Abstract: An important technique in stability theory for
differential equations is known as the direct method of Lyapunov. In
this work we deal global stability properties of Leptospirosis
transmission model by age group in Thailand. First we consider the
data from Division of Epidemiology Ministry of Public Health,
Thailand between 1997-2011. Then we construct the mathematical
model for leptospirosis transmission by eight age groups. The
Lyapunov functions are used for our model which takes the forms of
an Ordinary Differential Equation system. The globally
asymptotically for equilibrium states are analyzed.
Abstract: We apply a particle tracking technique to track the motion of individual pathogenic Leptospira. We observe and capture images of motile Leptospira by means of CCD and darkfield microscope. Image processing, statistical theories and simulations are used for data analysis. Based on trajectory patterns, mean square displacement, and power spectral density characteristics, we found that the motion modes are most likely to be directed motion mode (70%) and the rest are either normal diffusion or unidentified mode. Our findings may support the fact that why leptospires are very well efficient toward targeting internal tissues as a result of increase in virulence factor.
Abstract: In this work, we consider a deterministic model for
the transmission of leptospirosis which is currently spreading in the
Thai population. The SIR model which incorporates the features of
this disease is applied to the epidemiological data in Thailand. It is
seen that the numerical solutions of the SIR equations are in good
agreement with real empirical data. Further improvements are
discussed.
Abstract: Leptospirosis occurs worldwide (except the
poles of the earth), urban and rural areas, developed and
developing countries, especially in Thailand. It can be
transmitted to the human by rats through direct and indirect
ways. Human can be infected by either touching the infected rats
or contacting with water, soil containing urine from the infected
rats through skin, eyes and nose. The data of the people who
are infected with this disease indicates that most of the
patients are adults. The transmission of this disease is studied
through mathematical model. The population is separated into human
and rat. The human is divided into two classes, namely juvenile
and adult. The model equation is constructed for each class. The
standard dynamical modeling method is then used for
analyzing the behaviours of solutions. In addition, the
conditions of the parameters for the disease free and endemic
states are obtained. Numerical solutions are shown to support the
theoretical predictions. The results of this study guide the way to
decrease the disease outbreak.
Abstract: Leptospirosis is recognized as an important zoonosis
in tropical regions well as an important animal disease with
substantial loss in production. In this study, the model for the
transmission of the Leptospirosis disease to human population are
discussed. Model is described the vector population dynamics and
the Leptospirosis transmission to the human population are
discussed. Local analysis of equilibria are given. We confirm the
results by using numerical results.
Abstract: In this paper we develop and analyze the model for
the spread of Leptospirosis by age group in Thailand, between 1997
and 2010 by using mathematical modeling and computer simulation.
Leptospirosis is caused by pathogenic spirochetes of the genus
Leptospira. It is a zoonotic disease of global importance and an
emerging health problem in Thailand. In Thailand, leptospirosis is a
reportable disease, the top three age groups are 23.31% in 35-44
years olds group, 22.76% in 25-34 year olds group, 17.60% in 45-54
year olds group from reported leptospirosis between 1997 and 2010,
with a peak in 35-44 year olds group. Our paper, the Leptosipirosis
transmission by age group in Thailand is studied on the mathematical
model. Some analytical and simulation results are presented.