Abstract: The biomarker for colorectal cancer (CRC) is CEACAM-6 antigen (C6AG). Therefore, this study aims to develop a novel, simple and low-cost CEACAM-6 antigen immumosensor (C6AG-IMS), based on electrical impedance measurement, for precise determination of C6AG. A low-cost screen-printed graphite electrode was constructed and used as the sensor, with CEACAM-6 antibody (C6AB) immobilized on it. The procedures of sensor fabrication and antibody immobilization are simple and low-cost. Measurement of the electrical impedance at a definite frequency ranges (0.43 – 1.26 MHz) showed that the C6AG-IMS has an excellent linear (r2>0.9) response range (8.125 – 65 pg/mL), covering the normal physiological and pathological ranges of blood C6AG levels. Also, the C6AG-IMS has excellent reliability and validity, with the intraclass correlation coefficient being 0.97. In conclusion, a novel, simple, low-cost and reliable C6AG-IMS was designed and developed, being able to accurately determine blood C6AG levels in the range of pathological and normal physiological regions. The C6AG-IMS can provide a point-of-care and immediate screening results to the user at home.
Abstract: The autonomous mobile robot was designed and implemented which was capable of navigating in the industrial environments and did a job of picking objects from variable height and delivering it to another location following a predefined trajectory. In developing country like Bangladesh industrial robotics is not very prevalent yet, due to the high installation cost. The objective of this project was to develop an autonomous mobile robot for industrial application using the available resources in the local market at lower manufacturing cost. The mechanical system of the robot was comprised of locomotion, gripping and elevation system. Grippers were designed to grip objects of a predefined shape. Cartesian elevation system was designed for vertical movement of the gripper. PIC18F452 microcontroller was the brain of the control system. The prototype autonomous robot was fabricated for relatively lower load than the industry and the performance was tested in a virtual industrial environment created within the laboratory to realize the effectiveness.
Abstract: Oxidative stress makes up common incidents in
eukaryotic metabolism. The presence of diverse components
disturbing the equilibrium during oxygen metabolism increases
oxidative damage unspecifically in living cells. Body´s own
ubiquinone (Q10) seems to be a promising drug in defending the
heightened appearance of reactive oxygen species (ROS). Though, its
lipophilic properties require a new strategy in drug formulation to
overcome their low bioavailability. Consequently, the manufacture of
heterogeneous nanodispersions is in focus for medical applications.
The composition of conventional nanodispersions is made up of a
drug-consisting core and a surfactive agent, also named as surfactant.
Long-termed encapsulation of the surfactive components into tissues
might be the consequence of the use during medical therapeutics. The
potential of provoking side-effects is given by their nonbiodegradable
properties. Further improvements during fabrication
process use the incorporation of biodegradable components such as
modified γ-polyglutamic acid which decreases the potential of
prospective side-effects.
Abstract: The demand for higher performance graphics
continues to grow because of the incessant desire towards realism.
And, rapid advances in fabrication technology have enabled us to
build several processor cores on a single die. Hence, it is important to
develop single chip parallel architectures for such data-intensive
applications. In this paper, we propose an efficient PIM architectures
tailored for computer graphics which requires a large number of
memory accesses. We then address the two important tasks necessary
for maximally exploiting the parallelism provided by the architecture,
namely, partitioning and placement of graphic data, which affect
respectively load balances and communication costs. Under the
constraints of uniform partitioning, we develop approaches for optimal
partitioning and placement, which significantly reduce search space.
We also present heuristics for identifying near-optimal placement,
since the search space for placement is impractically large despite our
optimization. We then demonstrate the effectiveness of our partitioning
and placement approaches via analysis of example scenes; simulation
results show considerable search space reductions, and our heuristics
for placement performs close to optimal – the average ratio of
communication overheads between our heuristics and the optimal was
1.05. Our uniform partitioning showed average load-balance ratio of
1.47 for geometry processing and 1.44 for rasterization, which is
reasonable.
Abstract: This paper presents the development of low cost Nano membrane fabrication system. The system is specially designed for anodic aluminum oxide membrane. This system is capable to perform the processes such as anodization and electro-polishing. The designed machine was successfully tested for 'mild anodization' (MA) for 48 hours and 'hard anodization' (HA) for 3 hours at constant 0oC. The system is digitally controlled and guided for temperature maintenance during anodization and electro-polishing. The total cost of the developed machine is 20 times less than the multi-cooling systems available in the market which are generally used for this purpose.
Abstract: In this study, Friction Stir Processing (FSP) a recent grain refinement technique was employed to disperse micron-sized (2 *m) SiCp particles into aluminum alloy AA6063. The feasibility to fabricate bulk composites through FSP was analyzed and experiments were conducted at different traverse speeds and wider volumes of the specimens. Micro structural observation were carried out by employing optical microscopy test of the cross sections in both parallel and perpendicular to the tool traverse direction. Mechanical property including micro hardness was evaluated in detail at various regions on the specimen. The composites had an excellent bonding with aluminum alloy substrate and a significant increase of 30% in the micro hardness value of metal matrix composite (MMC) as to that of the base metal has observed. The observations clearly indicate that SiC particles were uniformly distributed within the aluminum matrix.
Abstract: The stab resistance performance of newly developed
fabric composites composed of hexagonal paper honeycombs, filled
with shear thickening fluid (STF), and woven Kevlar® fabric or
UHMPE was investigated in this study. The STF was prepared by
dispersing submicron SiO2 particles into polyethylene glycol (PEG).
Our results indicate that the STF-Kevlar composite possessed lower
penetration depth than that of neat Kevlar. In other words, the
STF-Kevlar composite can attain the same energy level in
stab-resistance test with fewer layers of Kevlar fabrics than that of the
neat Kevlar fabrics. It also indicates that STF can be used for the
fabrication of flexible body armors and can provide improved
protection against stab threats. We found that the stab resistance of the
STF-Kevlar composite increases with the increase of SiO2
concentration in STF. Moreover, the silica particles functionalized
with silane coupling agent can further improve the stab resistance.
Abstract: Design and evaluation of reciprocating compressors
should include a pulsation study. The object is to ensure that
predicted pulsation levels meet guidelines to limit vibration, shaking
forces, noise, associated pressure drops, horsepower losses and
fabrication cost and time to acceptable levels. This paper explains
procedures and recommendations to select and size pulsation
suppression devices to obtain optimum arrangement in terms of
pulsation, vibration, shaking forces, performance, reliability, safety,
operation, maintenance and commercial conditions. Model and
advanced formulations for pulsation study are presented. The effect
of the full fluid dynamic model on the prediction of pulsation waves
and resulting frequency spectrum distributions are discussed.
Advanced and optimum methods of controlling pulsations are
highlighted. Useful recommendations and guidelines for pulsation
control, piping pulsation analysis, pulsation vessel design, shaking
forces, low pressure drop orifices, pulsation study report and devices
to mitigate pulsation and shaking problems are discussed.
Abstract: Fully customized hardware based technology provides high performance and low power consumption by specializing the tasks in hardware but lacks design flexibility since any kind of changes require re-design and re-fabrication. Software based solutions operate with software instructions due to which a great flexibility is achieved from the easy development and maintenance of the software code. But this execution of instructions introduces a high overhead in performance and area consumption. In past few decades the reconfigurable computing domain has been introduced which overcomes the traditional trades-off between flexibility and performance and is able to achieve high performance while maintaining a good flexibility. The dramatic gains in terms of chip performance and design flexibility achieved through the reconfigurable computing systems are greatly dependent on the design of their computational units being integrated with reconfigurable logic resources. The computational unit of any reconfigurable system plays vital role in defining its strength. In this research paper an RFU based computational unit design has been presented using the tightly coupled, multi-threaded reconfigurable cores. The proposed design has been simulated for VLIW based architectures and a high gain in performance has been observed as compared to the conventional computing systems.
Abstract: Process-oriented software development is a new
software development paradigm in which software design is modeled
by a business process which is in turn translated into a process
execution language for execution. The building blocks of this
paradigm are software units that are composed together to work
according to the flow of the business process. This new paradigm
still exhibits the characteristic of the applications built with the
traditional software component technology. This paper discusses an
approach to apply a traditional technique for software component
fabrication to the design of process-oriented software units, called
process components. These process components result from
decomposing a business process of a particular application domain
into subprocesses, and these process components can be reused to
design the business processes of other application domains. The
decomposition considers five managerial goals, namely cost
effectiveness, ease of assembly, customization, reusability, and
maintainability. The paper presents how to design or decompose
process components from a business process model and measure
some technical features of the design that would affect the
managerial goals. A comparison between the measurement values
from different designs can tell which process component design is
more appropriate for the managerial goals that have been set. The
proposed approach can be applied in Web Services environment
which accommodates process-oriented software development.
Abstract: An advanced composite flywheel rotor consisting of
intra and inter hybrid rims was designed to optimally increase the energy capacity, and was manufactured using filament winding with
in-situ curing. The flywheel has recently attracted considerable attention from many investigators since it possesses great potential in
many energy storage applications, including electric utilities, hybrid or
electric automobiles, and space vehicles. In this investigation, a comprehensive study was conducted with the intent to implement
composites in high performance flywheel applications.The inner two
intra-hybrid rims (rims 1 and 2) were manufactured as a whole part
through continuous filament winding under in-situ curing conditions,
and so were the outer two rims (rims 3 and 4). The outer surface of rim
2 and the inner surface of rim 3 were CNC-tapered for press-fitting. Machined rims were finally press-fitted using a hydraulic press with a
maximum compressive force of approximately 1000 ton.
Abstract: This paper presents a new circuit arrangement for a
current-mode Wheatstone bridge that is suitable for low-voltage
integrated circuits implementation. Compared to the other proposed
circuits, this circuit features severe reduction of the elements number,
low supply voltage (1V) and low power consumption (
Abstract: In this paper, we present a vertical nanowire thin film transistor with gate-all-around architecture, fabricated using CMOS compatible processes. A novel method of fabricating polysilicon vertical nanowires of diameter as small as 30 nm using wet-etch is presented. Both n-type and p-type vertical poly-silicon nanowire transistors exhibit superior electrical characteristics as compared to planar devices. On a poly-crystalline nanowire of 30 nm diameter, high Ion/Ioff ratio of 106, low drain-induced barrier lowering (DIBL) of 50 mV/V, and low sub-threshold slope SS~100mV/dec are demonstrated for a device with channel length of 100 nm.
Abstract: The objective of this research is to investigate the
advantages of using large-diameter 0.7 inch prestressing strands in
pretention applications. The advantages of large-diameter strands are
mainly beneficial in the heavy construction applications. Bridges and
tunnels are subjected to a higher daily traffic with an exponential
increase in trucks ultimate weight, which raise the demand for higher
structural capacity of bridges and tunnels. In this research, precast
prestressed I-girders were considered as a case study. Flexure
capacities of girders fabricated using 0.7 inch strands and different
concrete strengths were calculated and compared to capacities of 0.6
inch strands girders fabricated using equivalent concrete strength.
The effect of bridge deck concrete strength on composite deck-girder
section capacity was investigated due to its possible effect on final
section capacity. Finally, a comparison was made to compare the
bridge cross-section of girders designed using regular 0.6 inch strands
and the large-diameter 0.7 inch. The research findings showed that
structural advantages of 0.7 inch strands allow for using fewer bridge
girders, reduced material quantity, and light-weight members. The
structural advantages of 0.7 inch strands are maximized when high
strength concrete (HSC) are used in girder fabrication, and concrete
of minimum 5ksi compressive strength is used in pouring bridge
decks. The use of 0.7 inch strands in bridge industry can partially
contribute to the improvement of bridge conditions, minimize
construction cost, and reduce the construction duration of the project.
Abstract: The National Bridge Inventory (NBI) includes more
than 600,000 bridges within the United States of America.
Prestressed concrete girder bridges represent one of the most widely
used bridge systems. The majority of these girder bridges were
constructed using 0.5 and 0.6 inch diameter strands. The main
impediments to using larger strand diameters are: 1) lack of prestress
bed capacities, 2) lack of structural knowledge regarding the transfer
and development length of larger strands, and 3) the possibility of
developing wider end zone cracks upon strand release.
This paper presents a study about using 0.7 inch strands in girder
fabrication. Transfer and development length were evaluated, and
girders were fabricated using 0.7 inch strands at different spacings.
Results showed that 0.7 inch strands can be used at 2.0 inch spacing
without violating the AASHTO LRFD Specifications, while attaining
superior performance in shear and flexure.
Abstract: The present work consecutively on synthesis and
characterization of composites, Al/Al alloy A 384.1 as matrix in
which the main ingredient as Al/Al-5% MgO alloy based metal
matrix composite. As practical implications the low cost processing
route for the fabrication of Al alloy A 384.1 and operational
difficulties of presently available manufacturing processes based in
liquid manipulation methods. As all new developments, complete
understanding of the influence of processing variables upon the final
quality of the product. And the composite is applied comprehensively
to the acquaintance for achieving superiority of information
concerning the specific heat measurement of a material through the
aid of thermographs. Products are evaluated concerning relative
particle size and mechanical behavior under tensile strength.
Furthermore, Taguchi technique was employed to examine the
experimental optimum results are achieved, owing to effectiveness of
this approach.
Abstract: This paper proposes a robot able to climb Columns.
This robot is not dependent on the diameter and material of the
columns. Some climbing robots have been designed up to now but
Koala robot was designed and fabricated for climbing columns
exclusively. Simple kinematics of climbing in the nature inspired us
to design this robot. We used two linear mechanisms to grip the
column. The gripper consists of a DC motor and a power screw
mechanism with a linear bushing as a guide. This mechanism
provides enough force to grip the column. In addition we needed an
actuator for climbing the column; hence, two pneumatic jacks were
used. All the mechanical parts were designed according to the
exerted forces and operational condition. The prototype can be
simply installed and controlled on the column by an inexperienced
operator. This robot is intended for inspection and surveillance of
pipes in oil industries and power poles in electric industries.
Abstract: This report shows the performance of composite
biodegradable film from chitosan, starch and sawdust fiber. The main
objectives of this research are to fabricate and characterize composite
biodegradable film in terms of morphology and physical properties.
The film was prepared by casting method. Sawdust fiber was used as
reinforcing agent and starch as polymer matrix in the casting
solution. The morphology of the film was characterized using atomic
force microscope (AFM). The result showed that the film has
smooth structure. Chemical composition of the film was investigated
using Fourier transform infrared (FTIR) where the result revealed
present of starch in the film. The thermal properties were
characterized using thermal gravimetric analyzer (TGA) and
differential scanning calorimetric (DSC) where the results showed
that the film has small difference in melting and degradation
temperature.
Abstract: This paper presents a low cost design of heart beat monitoring device using reflectance mode PhotoPlethysmography (PPG). PPG is known for its simple construction, ease of use and cost effectiveness and can provide information about the changes in cardiac activity as well as aid in earlier non-invasive diagnostics. The proposed device is divided into three phases. First is the detection of pulses through the fingertip. The signal is then passed to the signal processing unit for the purpose of amplification, filtering and digitizing. Finally the heart rate is calculated and displayed on the computer using parallel port interface. The paper is concluded with prototyping of the device followed by verification procedure of the heartbeat signal obtained in laboratory setting.
Abstract: Adhesively bonded joints are preferred over the
conventional methods of joining such as riveting, welding, bolting
and soldering. Some of the main advantages of adhesive joints
compared to conventional joints are the ability to join dissimilar
materials and damage-sensitive materials, better stress distribution,
weight reduction, fabrication of complicated shapes, excellent
thermal and insulation properties, vibration response and enhanced
damping control, smoother aerodynamic surfaces and an
improvement in corrosion and fatigue resistance. This paper presents
the behavior of adhesively bonded joints subjected to combined
thermal loadings, using the numerical methods. The joint
configuration considers aluminum as central adherend with six
different outer adherends including aluminum, steel, titanium, boronepoxy,
unidirectional graphite-epoxy and cross-ply graphite-epoxy
and epoxy-based adhesives. Free expansion of the joint in x
direction was permitted and stresses in adhesive layer and interfaces
calculated for different adherends.