Abstract: In the present work, forming limit diagrams and strain
distribution profile diagrams for extra deep drawing steel at room and
elevated temperatures have been determined experimentally by
conducting stretch forming experiments by using designed and
fabricated warm stretchforming tooling setup. With the help of
forming Limit Diagrams (FLDs) and strain, distribution profile
diagrams the formability of Extra Deep Drawing steel has been
analyzed and co-related with mechanical properties like strain
hardening COEFFICIENT (n) and normal anisotropy (r−). Mechanical
properties of EDD steel from room temperature to 4500C were
determined and discussed the impact of temperature on the properties
like work hardening exponent (n) anisotropy (r-) and strength
coefficient of the material. In addition, the fractured surfaces after
stretching have undergone the some metallurgical investigations and
attempt has been made to co-relate with the formability of EDD steel
sheets. They are co-related and good agreement with FLDs at various
temperatures.
Abstract: Interstitial free steels possess better formability and
have many applications in automotive industries. Forming limit
diagrams (FLDs) indicate the formability of materials which can be
determined by experimental and finite element (FE) simulations.
FLDs were determined experimentally by LDH test, utilizing optical
strain measurement system for measuring the strains in different
width specimens and by FE simulations in Interstitial Free (IF) and
Interstitial Free High Strength (IFHS) steels. In this study, the
experimental and FE simulated FLDs are compared and also the
stress based FLDs were investigated.
Abstract: Current research is targeting new molecular
mechanisms that underlie non-alcoholic fatty liver disease (NAFLD)
and associated metabolic disorders like non-alcoholic steatohepatitis
(NASH). Forty New Zealand White rabbits have been used and fed a
high protein (HP) and energy diet based on grains and containing
11.76 MJ/kg. Boron added to 3 experimental groups’ drinking waters
(30 mg boron/L) as boron compounds. Biochemical analysis
including boron levels, and nuclear magnetic resonance (NMR) based
metabolomics evaluation, and mRNA expression of peroxisome
proliferator-activated receptor (PPAR) family was performed. LDLcholesterol
concentrations alone were decreased in all the
experimental groups. Boron levels in serum and feces were increased.
Content of acetate was in about 2x higher for anhydrous borax group,
at least 3x higher for boric acid group. PPARα mRNA expression
was significantly decreased in boric acid group. Anhydrous borax
attenuated mRNA levels of PPARγ, which was further suppressed by
boric acid. Boron supplementation decreased the degenerative
alterations in hepatocytes. Except borax group other boron groups did
not have a pronounced change in tubular epithels of kidney. In
conclusion, high protein and energy diet leads hepatocytes’
degenerative changes which can be prevented by boron
supplementation. Boric acid seems to be more effective in this
situation.
Abstract: Nonalcoholic fatty liver disease (NAFLD) has
increased in conjunction with obesity. The accuracy of risk factors
for detecting NAFLD in obese adolescents has not undergone a
formal evaluation. The aim of this study was to evaluate predictors of
NAFLD among Egyptian female obese adolescents. The study
included 162 obese female adolescents. All were subjected to
anthropometry, biochemical analysis and abdominal ultrasongraphic
assessment. Metabolic syndrome (MS) was diagnosed according to
the IDF criteria. Significant association between presence of MS and
NAFLD was observed. Obese adolescents with NAFLD had
significantly higher levels of ALT, triglycerides, fasting glucose,
insulin, blood pressure and HOMA-IR, whereas decreased HDL-C
levels as compared with obese cases without NAFLD. Receiver–
operating characteristic (ROC) curve analysis shows that ALT is a
sensitive predictor for NAFLD, confirming that ALT can be used as a
marker of NAFLD.
Abstract: In this paper, we validate crater detection in moon surface image using FLDA. This proposal assumes that it is applied to SLIM (Smart Lander for Investigating Moon) project aiming at the pin-point landing to the moon surface. The point where the lander should land is judged by the position relations of the craters obtained via camera, so the real-time image processing becomes important element. Besides, in the SLIM project, 400kg-class lander is assumed, therefore, high-performance computers for image processing cannot be equipped. We are studying various crater detection methods such as Haar-Like features, LBP, and PCA. And we think these methods are appropriate to the project, however, to identify the unlearned images obtained by actual is insufficient. In this paper, we examine the crater detection using FLDA, and compare with the conventional methods.
Abstract: A new reverse phase-high performance liquid chromatography (RP-HPLC) method with fluorescent detector (FLD) was developed and optimized for Norfloxacin determination in human plasma. Mobile phase specifications, extraction method and excitation and emission wavelengths were varied for optimization. HPLC system contained a reverse phase C18 (5 μm, 4.6 mm×150 mm) column with FLD operated at excitation 330 nm and emission 440 nm. The optimized mobile phase consisted of 14% acetonitrile in buffer solution. The aqueous phase was prepared by mixing 2g of citric acid, 2g sodium acetate and 1 ml of triethylamine in 1 L of Milli-Q water was run at a flow rate of 1.2 mL/min. The standard curve was linear for the range tested (0.156–20 μg/mL) and the coefficient of determination was 0.9978. Aceclofenac sodium was used as internal standard. A detection limit of 0.078 μg/mL was achieved. Run time was set at 10 minutes because retention time of norfloxacin was 0.99 min. which shows the rapidness of this method of analysis. The present assay showed good accuracy, precision and sensitivity for Norfloxacin determination in human plasma with a new internal standard and can be applied pharmacokinetic evaluation of Norfloxacin tablets after oral administration in human.
Abstract: In this research, Forming Limit Diagrams for supertension
sheet metals which are using in automobile industry have
been obtained. The exerted strains to sheet metals have been
measured with four different methods and the errors of each method
have also been represented. These methods have been compared with
together and the most efficient and economic way of extracting of the
exerted strains to sheet metals has been introduced. In this paper total
error and uncertainty of FLD extraction procedures have been
derived. Determination of the measurement uncertainty in extracting
of FLD has a great importance in design and analysis of the sheet
metal forming process.
Abstract: Tailor-welded Blanks (TWBs) are tailor made for
different complex component designs by welding multiple metal
sheets with different thicknesses, shapes, coatings or strengths prior
to forming. In this study the Hemispherical Die Stretching (HDS) test
(out-of-plane stretching) of TWBs were simulated via
ABAQUS/Explicit to obtain the Forming Limit Diagrams (FLDs) of
Stainless steel (AISI 304) laser welded blanks with different
thicknesses. Two criteria were used to detect the start of necking to
determine the FLD for TWBs and parent sheet metals. These two
criteria are the second derivatives of the major and thickness strains
that are given from the strain history of simulation. In the other word,
in these criteria necking starts when the second derivative of
thickness or major strain reaches its maximum. With having the time
of onset necking, one can measure the major and minor strains at the
critical area and determine the forming limit curve.
Abstract: One of the approaches enabling people with amputated
limbs to establish some sort of interface with the real world includes
the utilization of the myoelectric signal (MES) from the remaining
muscles of those limbs. The MES can be used as a control input to a
multifunction prosthetic device. In this control scheme, known as the
myoelectric control, a pattern recognition approach is usually utilized
to discriminate between the MES signals that belong to different
classes of the forearm movements. Since the MES is recorded using
multiple channels, the feature vector size can become very large. In
order to reduce the computational cost and enhance the generalization
capability of the classifier, a dimensionality reduction method is
needed to identify an informative yet moderate size feature set. This
paper proposes a new fuzzy version of the well known Fisher-s
Linear Discriminant Analysis (LDA) feature projection technique.
Furthermore, based on the fact that certain muscles might contribute
more to the discrimination process, a novel feature weighting scheme
is also presented by employing Particle Swarm Optimization (PSO)
for estimating the weight of each feature. The new method, called
PSOFLDA, is tested on real MES datasets and compared with other
techniques to prove its superiority.