Abstract: The paper identifies the features of Polish sports clubs
in the particular organizational forms: profit and nonprofit.
Identification and description of these features is carried out in terms
of financial efficiency of the given organizational form. Under the
terms of the efficiency the research allows you to specify the
advantages of particular organizational sports club form and the
following limitations. Paper considers features of sports clubs in
range of Polish conditions as legal regulations. The sources of the
functioning efficiency of sports clubs may lie in the organizational
forms in which they operate. Each of the available forms can be
considered either a for-profit or nonprofit enterprise. Depending on
this classification there are different capabilities of increasing
organizational and financial efficiency of a given sports club. Authors
start with general classification and difference between for-profit and
non-profit sport clubs. Next identifies specific financial and
organizational conditions of both organizational form and then show
examples of mixed activity forms and their efficiency effect.
Abstract: The aim of study was to analyze the functioning the
new model of criminal corporate responsibility in Poland. The need
to introduce into the Polish legal system liability of corporate
(collective entities) has resulted, among others, from the Polish
Republic's international commitments, in particular related to
membership in the European Union. The study showed that responsibility of collective entities under
the Act has a criminal nature. The main question concerns the ability
of the collective entity to be brought to guilt under criminal law
sense. Polish criminal law knows only the responsibility of individual
persons. So far, guilt as a personal feature of action, based on the
ability of the offender to feel in his psyche, could be considered only
in relation to the individual person, while the said Act destroyed this
conviction. Guilt of collective entity must be proven under at least
one of the three possible forms: the guilt in the selection or
supervision and so called organizational guilt. In addition, research in
article has resolved the issue how the principle of proportionality in
relation to criminal measures in response of collective entities should
be considered. It should be remembered that the legal subjectivity of
collective entities, including their rights and freedoms, is an
emanation of the rights and freedoms of individual persons which
create collective entities and through these entities implement their
rights and freedoms. The whole study was proved that the adopted Act largely reflects
the international legal regulations but also contains the unknown and
original legislative solutions.
Abstract: New environmental regulations and the increasing
market preference for companies that respect the ecosystem had
encouraged the industry to look after new treatments for its effluents.
The sugar industry, one of the largest emitter of environmental
pollutants, follows this tendency. Membrane technology is
convenient for separation of suspended solids, colloids and high
molecular weight materials that are present in a wastewater from
sugar industry. The idea is to microfilter the wastewater, where the
permeate passes through the membrane and becomes available for
recycle and re-use in the sugar manufacturing process. For
microfiltration of this effluent a tubular ceramic membrane was used
with a pore size of 200 nm at transmembrane pressure in range of 1–3
bars and in range of flow rate of 50–150 l/h. Kenics static mixer was
used for permeate flux enhancement. Turbidity and suspended solids
were removed and the permeate flux was continuously monitored
during the microfiltration process. The flux achieved after 90 minutes
of microfiltration was in a range of 50–70 l/m2h. The obtained
turbidity decrease was in the range of 50-99 % and total amount of
suspended solids was removed.
Abstract: The recent interest in alternative and renewable
energy systems results in increased installed capacity ratio of such
systems in total energy production of the world. Specifically, Wind
Energy Conversion Systems (WECS) draw significant attention
among possible alternative energy options, recently. On the contrary
of the positive points of penetrating WECS in all over the world in
terms of environment protection, energy independence of the
countries, etc., there are significant problems to be solved for the grid
connection of large scale WECS. The reactive power regulation,
voltage variation suppression, etc. can be presented as major issues to
be considered in this regard. Thus, this paper evaluates the
application of a Static VAr Compensator (SVC) unit for the reactive
power regulation and operation continuity of WECS during a fault
condition. The system is modeled employing the IEEE 13 node test
system. Thus, it is possible to evaluate the system performance with
an overall grid simulation model close to real grid systems. The
overall simulation model is developed in
MATLAB/Simulink/SimPowerSystems® environments and the
obtained results effectively match the target of the provided study.
Abstract: Latin America is probably the region with greater
social inequality, contrary to the amount of rights enshrined in their
constitutions. In the last decade of the twentieth century, the area
resulted in significant changes to democratization and constitutional
changes. Through low-key public policy, political leaders activated
participation in the culture of human rights. The struggle for social
rights in Latin America has been a constant regulation. His
consecration at the constitutional level has chained search
application. The constitutionalization and judicial protection of these
rights have been crucial in countries like Argentina, Venezuela, Peru
and Colombia. This paper presents an analytical view on the
constitutionalization of social rights in the Latin American context
and its justiciability.
Abstract: Several embryonic cellular mechanism including cell
cycle, growth and apoptosis are regulated by phosphatidylinositol-3-
kinase (PI3K)/Akt signaling pathway. The goal of present study is to
determine the effects of annatto (Bixa orellana)-derived δ-tocotrienol
(δ-TCT) on the regulations of PI3K/Akt genes in murine morula.
Twenty four 6-8 week old (23-25g) female balb/c mice were
randomly divided into four groups (G1-G4; n=6). Those groups were
subjected to the following treatments for 7 consecutive days: G1
(control) received tocopherol stripped corn oil, G2 was given 60
mg/kg/day of δ-TCT mixture (contains 90% delta & 10% gamma
isomers), G3 was given 60 mg/kg/day of pure δ-TCT (>98% purity)
and G4 received 60 mg/kg/day α-TOC. On Day 8, females were
superovulated with 5 IU Pregnant Mare’s Serum Gonadotropin
(PMSG) for 48 hours followed with 5 IU human Chorionic
Gonadotropin (hCG) before mated with males at the ratio of 1:1.
Females were sacrificed by cervical dislocation for embryo collection
48 hours post-coitum. About fifty morulas from each group were
used in the gene expression analyses using Affymetrix QuantiGene
Plex 2.0 Assay. Present data showed a significant increase (p
Abstract: The growth of organic farming practices in the last
few decades is continuing to stimulate the international debate about
this alternative food market. As a part of a PhD project research
about embeddedness in Alternative Food Networks (AFNs), this
paper focuses on the promotional aspects of organic farms websites
from the Madrid region. As a theoretical tool, some knowledge
categories drawn on the geographic studies literature are used to
classify the many ideas expressed in the web pages. By analysing
texts and pictures of 30 websites, the study aims to question how and
to what extent actors from organic world communicate to the
potential customers their personal beliefs about farming practices,
products qualities, and ecological and social benefits. Moreover, the
paper raises the question of whether organic farming laws and
regulations lack of completeness about the social and cultural aspects
of food.
Abstract: The use of hydroelectric pump-storage system at large
scale, MW-size systems, is already widespread around the world.
Designed for large scale applications, pump-storage station can be
scaled-down for small, remote residential applications. Given the cost
and complexity associated with installing a substation further than
100 miles from the main transmission lines, a remote, independent
and self-sufficient system is by far the most feasible solution. This
article is aiming at the design of wind and solar power generating
system, by means of pumped-storage to replace the wind and /or solar
power systems with a battery bank energy storage. Wind and solar
pumped-storage power generating system can reduce the cost of
power generation system, according to the user's electricity load and
resource condition and also can ensure system reliability of power
supply. Wind and solar pumped-storage power generation system is
well suited for remote residential applications with intermittent wind
and/or solar energy. This type of power systems, installed in these
locations, could be a very good alternative, with economic benefits
and positive social effects. The advantage of pumped storage power
system, where wind power regulation is calculated, shows that a
significant smoothing of the produced power is obtained, resulting in
a power-on-demand system’s capability, concomitant to extra
economic benefits.
Abstract: Out-migration is an important issue for Georgia as
well as since independence has loosed due to emigration one fifth of
its population. During Soviet time out-migration from USSR was
almost impossible and one of the most important instruments in
regulating population movement within the Soviet Union was the
system of compulsory residential registrations, so-called “propiska”.
Since independent here was not any regulation for migration from
Georgia. The majorities of Georgian migrants go abroad by tourist
visa and then overstay, becoming the irregular labor migrants. The
official statistics on migration published for this period was based on
the administrative system of population registration, were
insignificant in terms of numbers and did not represent the real scope
of these migration movements. This paper discusses the data quality
and methodology of migration statistics in Georgia and we are going
to answer the questions: what is the real reason of increasing
immigration flows according to the official numbers since 2000s?
Abstract: The article proposed intends to analyze the possibility
(and conditions) of a media regulation law in a democratic rule of law
in the twenty-first century. To do so, will be presented initially the
idea of the public sphere (by Jürgen Habermas), showing how it is
presented as an interface between the citizen and the state (or the
private and public) and how important is it in a deliberative
democracy. Based on this paradigm, the traditional perception of the
role of public information (such as system functional element) and on
the possibility of media regulation will be exposed, due to the public
nature of their activity. A critical argument will then be displayed
from two different perspectives: a) the formal function of the current
media information, considering that the digital age has fragmented
the information access; b) the concept of a constructive democracy,
which reduces the need for representation, changing the strategic
importance of the public sphere. The question to be addressed (based
on the comparative law) is if the regulation is justified in a
polycentric democracy, especially when it operates under the digital
age (with immediate and virtual communication). The proposal is to
be presented in the sense that even in a twenty-first century the media
in a democratic rule of law still has an extremely important role and
may be subject to regulation, but this should be on terms very
different (and narrower) from those usually defended.
Abstract: The relationship between the state and the religion is
different based on the fact that how powerful is the religion faith in a
state and of the influences that affected the views of the constitution
drafters according to the constitutional system they were based to
draft their constitution. This paper aims at providing, through a
comparative methodology, how it is regulated by the constitution the
relationship between the state and the religion. The object of this
study are the constitutions of Italy as a nation with catholic religious
tradition, Greece as a nation with orthodox religion tradition, and
Turkey as a nation which represents Muslim religion, while Albania
as a nation known for its religious plurality. In particular, the analysis
will be focused on the secular or religious principle provided in the
constitution of each respective state. This comparative overview
intends to discern which of the states analyzed is more tolerant and
fully respects the freedom of religion. It results that most of the states
subject of this study, despite their religious tradition have chosen the
secular principle in their constitutions, but the religious freedom is
differently guaranteed.
Abstract: Transmission system performance analysis is vital to
proper planning and operations of power systems in the presence of
deregulation. Key performance indicators (KPIs) are often used as
measure of degree of performance. This paper gives a novel method
to determine the transmission efficiency by evaluating the ratio of
real power losses incurred from a specified transfer direction.
Available Transmission Transfer Efficiency (ATTE) expresses the
percentage of real power received resulting from inter-area available
power transfer. The Tie line (Rated system path) performance is seen
to differ from system wide (Network response) performance and
ATTE values obtained are transfer direction specific. The required
sending end quantities with specified receiving end ATC and the
receiving end power circle diagram are obtained for the tie line
analysis. The amount of real power loss load relative to the available
transfer capability gives a measure of the transmission grid
efficiency.
Abstract: Cortisol is essential to the regulation of the immune
system and yawning is a pathological symptom of multiple sclerosis
(MS). Electromyography activity (EMG) in the jaw muscles typically
rises when the muscles are moved and with yawning is highly
correlated with cortisol levels in healthy people. Saliva samples from
59 participants were collected at the start and after yawning, or at the
end of the presentation of yawning-provoking stimuli, in the absence
of a yawn, together with EMG data and questionnaire data: Hospital
Anxiety and Depression Scale, Yawning Susceptibility Scale,
General Health Questionnaire, demographic, health details. Exclusion
criteria: chronic fatigue, diabetes, fibromyalgia, heart condition, high
blood pressure, hormone replacement therapy, multiple sclerosis,
stroke. Significant differences were found between the saliva cortisol
samples for the yawners, t (23) = -4.263, p = 0.000, as compared with
the non-yawners between rest and post-stimuli, which was nonsignificant.
Significant evidence was found to support the Thompson
Cortisol Hypothesis suggesting that rises in cortisol levels are
associated with yawning. Further research is exploring the use of
cortisol as an early diagnostic tool for MS. Ethics approval granted
and professional code of conduct, confidentiality, and safety issues
are approved therein.
Abstract: In emerging economies, recycling is an opportunity
for the cities to increase the lifespan of sanitary landfills, reduce the
costs of the solid waste management, decrease the environmental
problems of the waste treatment through reincorporate waste in the
productive cycle and protect and develop people’s livelihoods of
informal waste pickers. However, few studies have analysed the
possibilities and strategies to integrate formal and informal sectors in
the solid waste management for the benefit of both. This study seek
to make a strength, weakness, opportunity, and threat (SWOT)
analysis in three recycling associations of Bogotá with the aim to
understand and determine the situation of recycling from perspective
of informal sector in its transition to enter as authorized waste
providers. Data used in the analysis are derived from multiple
strategies such as literature review, the Bogota’s recycling database,
focus group meetings, governmental reports, national laws and
regulations and specific interviews with key stakeholders. Results of
this study show as the main stakeholders of formal and informal
sector of waste management can identify the internal and internal
conditions of recycling in Bogotá. Several strategies were designed
based on the SWOTs determined, could be useful for Bogotá to
advance and promote recycling as a key strategy for integrated
sustainable waste management in the city.
Abstract: In general, codes and regulations consider seismic
loads only for completed structures of the bridges while, evaluation
of incomplete structure of bridges, especially those constructed by
free cantilever method, under these loads is also of great importance.
Hence, this research tried to study the behavior of incomplete
structure of common bridge type (box girder bridge), in construction
phase under vertical seismic loads. Subsequently, the paper provided
suitable guidelines and solutions to resist this destructive
phenomenon. Research results proved that use of preventive methods
can significantly reduce the stresses resulted from vertical seismic
loads in box cross sections to an acceptable range recommended by
design codes.
Abstract: Morphological interaction of porcine cumulus-oocyte
complexes (pCOCs) was investigated on in vitro condition using
electron microscope (SEM and TEM). The totals of 1,923 oocytes
were round in shape, surrounded by Zona pellucida with layer of
cumulus cells ranging between 59.29-202.14 μm in size. They were
classified into intact-, multi-, partial cumulus cell layer oocyte, and
completely denuded oocyte, at the percentage composition of 22.80%
32.70%, 18.60%, and 25.90 % respectively. The pCOCs classified as
intact- and multi cumulus cell layer oocytes were further culturing at
37°C with 5% CO2, 95% air atmosphere and high humidity for 44 h
in M199 with Earle’s salts supplemented with 10% HTFCS, 2.2
mg/mL NaHCO3, 1 M Hepes, 0.25 mM pyruvate, 15 μg/mL porcine
follicle-stimulating hormone, 1 μg/mL LH, 1μg/mL estradiol with
ethanol, and 50 μg/mL gentamycin sulfate. On electron microscope
study, cumulus cells were found to stick their processes to secrete
substance from the sac-shape end into Zona pellucida of the oocyte
and also communicated with the neighboring cells through their
microvilli on the beginning of incubation period. It is believed that
the cumulus cells communicate with the oocyte by inserting the
microvilli through this gap and embedded in the oocyte cytoplasm
before secreting substance, through the sac-shape end of the
microvilli, to inhibit primary oocyte development at the prophase I.
Morphological changes of the complexes were observed after
culturing for 24-44 h. One hundred percentages of the cumulus layers
were expanded and cumulus cells were peeling off from the oocyte
surface. In addition, the round-shape cumulus cells transformed
themselves into either an elongate shape or a columnar shape, and no
communication between cumulus neighboring cells. After 44 h of
incubation time, diameter of oocytes surrounded by cumulus cells
was larger than 0 h incubation. The effect of hormones in culture
medium is exerted by their receptors present in porcine oocyte. It is
likely that all morphological changes of the complexes after hormone
treatment were to allow maturation of the oocyte. This study
demonstrated that the association of hormones in M199 could
promote porcine follicle activation in 44 h in vitro condition. This
culture system should be useful for studying the regulation of early
follicular growth and development, especially because these follicles represent a large source of oocytes that could be used in vitro for cell
technology.
Abstract: Neuroplasticity or the flexibility of the neural system
is the ability of the brain to adapt to the lack or deterioration of sense
and the capability of the neural system to modify itself through
changing shape and function. Not only have studies revealed that
neuroplasticity does not end in childhood, but also they have proven
that it continues till the end of life and is not limited to the neural
system and covers the cognitive system as well. In the field of
cognition, neuroplasticity is defined as the ability to change old
thoughts according to new conditions and the individuals' differences
in using various styles of cognitive regulation inducing several social,
emotional and cognitive outcomes. This paper attempts to discuss and
define major theories and principles of neuroplasticity and elaborate
on nature or nurture.
Abstract: Array-based gene expression analysis is a powerful
tool to profile expression of genes and to generate information on
therapeutic effects of new anti-cancer compounds. Anti-apoptotic
effect of thymoquinone was studied in MCF7 breast cancer cell line
using gene expression profiling with cDNA microarray. The purity
and yield of RNA samples were determined using RNeasyPlus Mini
kit. The Agilent RNA 6000 NanoLabChip kit evaluated the quantity
of the RNA samples. AffinityScript RT oligo-dT promoter primer
was used to generate cDNA strands. T7 RNA polymerase was used to
convert cDNA to cRNA. The cRNA samples and human universal
reference RNA were labelled with Cy-3-CTP and Cy-5-CTP,
respectively. Feature Extraction and GeneSpring softwares analysed
the data. The single experiment analysis revealed involvement of 64
pathways with up-regulated genes and 78 pathways with downregulated
genes. The MAPK and p38-MAPK pathways were
inhibited due to the up-regulation of PTPRR gene. The inhibition of
p38-MAPK suggested up-regulation of TGF-ß pathway. Inhibition of
p38-MAPK caused up-regulation of TP53 and down-regulation of
Bcl2 genes indicating involvement of intrinsic apoptotic pathway.
Down-regulation of CARD16 gene as an adaptor molecule regulated
CASP1 and suggested necrosis-like programmed cell death and
involvement of caspase in apoptosis. Furthermore, down-regulation
of GPCR, EGF-EGFR signalling pathways suggested reduction of
ER. Involvement of AhR pathway which control cytochrome P450
and glucuronidation pathways showed metabolism of Thymoquinone.
The findings showed differential expression of several genes in
apoptosis pathways with thymoquinone treatment in estrogen
receptor-positive breast cancer cells.
Abstract: In its efforts to utilize the information and
communication technology to enhance the quality of public service
delivery, national and local governments around the world are
competing to introduce more ICT applications as tools to automate
processes related to law enforcement or policy execution, increase
citizen orientation, trust, and satisfaction, and create one-stop-shops
for public services. In its implementation, e-Government ICTs need
to maintain transparency, participation, and collaboration. Due to this
diverse of mixed goals and requirements, e-Government systems
need to be designed based on special design considerations in order
to eliminate the risks of failure to compliance to government
regulations, citizen dissatisfaction, or market repulsion.
In this article we suggest a framework with guidelines for
designing government information systems that takes into
consideration the special requirements of the public sector. Then we
introduce two case studies and show how applying those guidelines
would result in a more solid system design.
Abstract: One of the best examples, in evolution of the public
procurement, from post-soviet countries are reforms carried out in
Georgia, which brought them close to international standards of
procurement. In Georgia, public procurement legislation started
functioning short after gaining independence. The reform has passed
several stages and came in the form as it is today. It should also be
noted, that countries with economy in transition, including Georgia,
implemented all the reforms in public procurement based on
recommendations and support of World Bank, the United Nations
and other international organizations.
The aim of first adopted law was regulation of the procurement
process of budget-organizations, transparency and creation of
competitive environment for private companies to access state funds
legally. The priorities were identified quite clearly in the wording of
the law, but operation/function of this law could not be reached on its
level, because of some objective and subjective reasons. The high
level of corruption in all levels of governance can be considered as a
main obstacle reason and of course, it is natural, that it had direct
impact on the procurement process, as well as on transparency and
rational use of state funds. These circumstances were the reasons that
reforms in this sphere continued, to improve procurement process, in
particular, the first wave of reforms began after several years. Public
procurement agency carried out reform with World Bank with main
purpose of smartening the procurement legislation and its
harmonization with international treaties and agreements. Also with
the support of World Bank various activities were carried out to raise
awareness of participants involved in procurement system.
Further major changes in the legislation were filed bit later, which
was also directed towards the improvement and smarten of the
procurement process. The third wave of the reform more or less
guaranteed the transparency of the procurement process, which later
became the basis for the rational spending of state funds. The reform
of the procurement system completely changed the procedures.
Carried out reform in Georgia resulted in introducing new
electronic tendering system, which benefit the transparency of the
process, after this became the basis for the further development of a
competitive environment, which become a prerequisite for the state
rational spending. Increased number of supplier organizations
participating in the procurement process resulted in reduction of the
estimated cost and the actual cost.
Assessment of the reforms in Georgia in the field of public
procurement can be concluded, that proper regulation of the sector
and relevant policy may proceed to rational and transparent spending
of the budget from country’s state institutions. Also, the business
sector has the opportunity to work in competitive market conditions
and to make a preliminary analysis, which is a prerequisite for future
strategy and development.