Abstract: The main aim is to perform mutational analysis of CTLA4 gene Exon 1 in SLE patients. A total of 61 SLE patients fulfilling “American College of Rheumatology (ACR) criteria" and 61 controls were enrolled in this study. The region of CTLA4 gene exon 1 was amplified by using Step-down PCR technique. Extracted DNA of band 354 bp was sequenced to analyze mutations in the exon-1 of CTLA-4 gene. Further, protein sequences were identified from nucleotide sequences of CTLA4 Exon 1 by using Expasy software and through Blast P software it was found that CTLA4 protein sequences of Pakistani SLE patients were similar to that of Chinese SLE population. No variations were found after patients sequences were compared with that of the control sequence. Furthermore it was found that CTLA4 protein sequences of Pakistani SLE patients were similar to that of Chinese SLE population. Thus CTLA4 gene may not be responsible for an autoimmune disease SLE.
Abstract: The study investigated the hydrophilic to hydrophobic
transition of modified polyacrylamide hydrogel with the inclusion of
N-isopropylacrylamide (NIAM). The modification was done by
mimicking micellar polymerization, which resulted in better
arrangement of NIAM chains in the polyacrylamide network. The
degree of NIAM arrangement is described by NH number. The
hydrophilic to hydrophobic transition was measured through the
partition coefficient, K, of Orange II and Methylene Blue in hydrogel
and in water. These dyes were chosen as a model for solutes with
different degree of hydrophobicity. The study showed that the
hydrogel with higher NH values resulted in better solubility of both
dyes. Moreover, in temperature above the lower critical solution
temperature (LCST) of Poly(N-isopropylacrylamide) (PNIAM)also
caused the collapse of NIPAM chains which results in a more
hydrophobic environment that increases the solubility of Methylene
Blue and decreases the solubility of Orange II in the hydrogels with
NIPAM present.
Abstract: A techno-economic evaluation for efficient use of
energy in a large scale industrial plant of methanol is carried out.
This assessment is based on integration of a gas turbine with an
existing plant of methanol in which the outlet gas products of
exothermic reactor is expanded to power generation. Also, it is
decided that methanol production rate is constant through addition of
power generation system to the existing methanol plant. Having
incorporated a gas turbine with the existing plant, the economic
results showed total investment of MUSD 16.9, energy saving of 3.6
MUSD/yr with payback period of approximately 4.7 years.
Abstract: In this paper a mixed method by combining an evolutionary and a conventional technique is proposed for reduction of Single Input Single Output (SISO) continuous systems into Reduced Order Model (ROM). In the conventional technique, the mixed advantages of Mihailov stability criterion and continued Fraction Expansions (CFE) technique is employed where the reduced denominator polynomial is derived using Mihailov stability criterion and the numerator is obtained by matching the quotients of the Cauer second form of Continued fraction expansions. Then, retaining the numerator polynomial, the denominator polynomial is recalculated by an evolutionary technique. In the evolutionary method, the recently proposed Differential Evolution (DE) optimization technique is employed. DE method is based on the minimization of the Integral Squared Error (ISE) between the transient responses of original higher order model and the reduced order model pertaining to a unit step input. The proposed method is illustrated through a numerical example and compared with ROM where both numerator and denominator polynomials are obtained by conventional method to show its superiority.
Abstract: In this paper we propose an intelligent agent approach
to control the electric power grid at a smaller granularity in order to
give it self-healing capabilities. We develop a method using the
influence model to transform transmission substations into
information processing, analyzing and decision making (intelligent
behavior) units. We also develop a wireless communication method
to deliver real-time uncorrupted information to an intelligent
controller in a power system environment. A combined networking
and information theoretic approach is adopted in meeting both the
delay and error probability requirements. We use a mobile agent
approach in optimizing the achievable information rate vector and in
the distribution of rates to users (sensors). We developed the concept
and the quantitative tools require in the creation of cooperating semiautonomous
subsystems which puts the electric grid on the path
towards intelligent and self-healing system.
Abstract: Nanoemulsions are a class of emulsions with a droplet
size in the range of 50–500 nm and have attracted a great deal of
attention in recent years because it is unique characteristics. The
physicochemical properties of nanoemulsion suggests that it can be
successfully used to recover the residual oil which is trapped in the
fine pore of reservoir rock by capillary forces after primary and
secondary recovery. Oil-in-water nanoemulsion which can be formed
by high-energy emulsification techniques using specific surfactants
can reduce oil-water interfacial tension (IFT) by 3-4 orders of
magnitude. The present work is aimed on characterization of oil-inwater
nanoemulsion in terms of its phase behavior, morphological
studies; interfacial energy; ability to reduce the interfacial tension and
understanding the mechanisms of mobilization and displacement of
entrapped oil blobs by lowering interfacial tension both at the
macroscopic and microscopic level. In order to investigate the
efficiency of oil-water nanoemulsion in enhanced oil recovery
(EOR), experiments were performed to characterize the emulsion in
terms of their physicochemical properties and size distribution of the
dispersed oil droplet in water phase. Synthetic mineral oil and a series
of surfactants were used to prepare oil-in-water emulsions.
Characterization of emulsion shows that it follows pseudo-plastic
behaviour and drop size of dispersed oil phase follows lognormal
distribution. Flooding experiments were also carried out in a
sandpack system to evaluate the effectiveness of the nanoemulsion as
displacing fluid for enhanced oil recovery. Substantial additional
recoveries (more than 25% of original oil in place) over conventional
water flooding were obtained in the present investigation.
Abstract: Today with the rapid growth of telecommunications equipment, electronic and developing more and more networks of power, influence of electromagnetic waves on one another has become hot topic discussions. So in this article, this issue and appropriate mechanisms for EMC operations have been presented. First, a source of alternating current (50 Hz) and a clear victim in a certain distance from the source is placed. With this simple model, the effects of electromagnetic radiation from the source to the victim will be investigated and several methods to reduce these effects have been presented. Therefore passive and active shields have been used. In some steps, shielding effectiveness of proposed shields will be compared. . It should be noted that simulations have been done by the finite element method (FEM).
Abstract: The aim of this paper is to study in depth some
methodological aspects of social interventation, focusing on desirable
passage from social maternage method to peer advocacy method. For
this purpose, we intend analyze social and organizative components,
that affect operator-s professional action and that are part of his
psychological environment, besides the physical and social one. In
fact, operator-s interventation should not be limited to a pure supply
of techniques, nor to take shape as improvised action, but “full of
good purposes".
Abstract: The purpose of semantic web research is to transform
the Web from a linked document repository into a distributed knowledge base and application platform, thus allowing the vast range of available information and services to be more efficiently
exploited. As a first step in this transformation, languages such as
OWL have been developed. Although fully realizing the Semantic Web still seems some way off, OWL has already been very
successful and has rapidly become a defacto standard for ontology
development in fields as diverse as geography, geology, astronomy,
agriculture, defence and the life sciences. The aim of this paper is to classify key concepts of Semantic Web as well as introducing a new
practical approach which uses these concepts to outperform Word Wide Web.
Abstract: Hidden Markov Model (HMM) is a stochastic method
which has been used in various signal processing and character
recognition. This study proposes to use HMM to recognize Javanese
characters from a number of different handwritings, whereby HMM
is used to optimize the number of state and feature extraction. An
85.7 % accuracy is obtained as the best result in 16-stated vertical
model using pure HMM. This initial result is satisfactory for
prompting further research.
Abstract: We measured the major and trace element contents
and Rb-Sr isotopic compositions of 12 tektites from the Maoming
area, Guandong province (south China). All the samples studied are
splash-form tektites which show pitted or grooved surfaces with
schlieren structures on some surfaces. The trace element ratios Ba/Rb
(avg. 4.33), Th/Sm (avg. 2.31), Sm/Sc (avg. 0.44), Th/Sc (avg. 1.01) ,
La/Sc (avg. 2.86), Th/U (avg. 7.47), Zr/Hf (avg. 46.01) and the rare
earth elements (REE) contents of tektites of this study are similar to the
average upper continental crust. From the chemical composition, it is
suggested that tektites in this study are derived from similar parental
terrestrial sedimentary deposit which may be related to post-Archean
upper crustal rocks. The tektites from the Maoming area have high
positive εSr(0) values-ranging from 176.9~190.5 which indicate that
the parental material for these tektites have similar Sr isotopic
compositions to old terrestrial sedimentary rocks and they were not
dominantly derived from recent young sediments (such as soil or
loess). The Sr isotopic data obtained by the present study support the
conclusion proposed by Blum et al. (1992)[1] that the depositional age
of sedimentary target materials is close to 170Ma (Jurassic). Mixing
calculations based on the model proposed by Ho and Chen (1996)[2]
for various amounts and combinations of target rocks indicate that the
best fit for tektites from the Maoming area is a mixture of 40% shale,
30% greywacke, 30% quartzite.
Abstract: Traffic management in an urban area is highly facilitated by the knowledge of the traffic conditions in every street or highway involved in the vehicular mobility system. Aim of the paper is to propose a neuro-fuzzy approach able to compute the main parameters of a traffic system, i.e., car density, velocity and flow, by using the images collected by the web-cams located at the crossroads of the traffic network. The performances of this approach encourage its application when the traffic system is far from the saturation. A fuzzy model is also outlined to evaluate when it is suitable to use more accurate, even if more time consuming, algorithms for measuring traffic conditions near to saturation.
Abstract: This paper presents an indirect adaptive stabilization
scheme for first-order continuous-time systems under saturated input
which is described by a sigmoidal function. The singularities are
avoided through a modification scheme for the estimated plant
parameter vector so that its associated Sylvester matrix is guaranteed
to be non-singular and then the estimated plant model is controllable.
The modification mechanism involves the use of a hysteresis
switching function. An alternative hybrid scheme, whose estimated
parameters are updated at sampling instants is also given to solve a
similar adaptive stabilization problem. Such a scheme also uses
hysteresis switching for modification of the parameter estimates so as
to ensure the controllability of the estimated plant model.
Abstract: In this paper, an algorithm for detecting and attenuating
puff noises frequently generated under the mobile environment is
proposed. As a baseline system, puff detection system is designed
based on Gaussian Mixture Model (GMM), and 39th Mel Frequency
Cepstral Coefficient (MFCC) is extracted as feature parameters. To
improve the detection performance, effective acoustic features for puff
detection are proposed. In addition, detected puff intervals are
attenuated by high-pass filtering. The speech recognition rate was
measured for evaluation and confusion matrix and ROC curve are used
to confirm the validity of the proposed system.
Abstract: As a tool for human spatial cognition and thinking, the map has been playing an important role. Maps are perhaps as fundamental to society as language and the written word. Economic and social development requires extensive and in-depth understanding of their own living environment, from the scope of the overall global to urban housing. This has brought unprecedented opportunities and challenges for traditional cartography . This paper first proposed the concept of scaleless-map and its basic characteristics, through the analysis of the existing multi-scale representation techniques. Then some strategies are presented for automated mapping compilation. Taking into account the demand of automated map compilation, detailed proposed the software - WJ workstation must have four technical features, which are generalization operators, symbol primitives, dynamically annotation and mapping process template. This paper provides a more systematic new idea and solution to improve the intelligence and automation of the scaleless cartography.
Abstract: To analyze the behavior of Petri nets, the accessibility
graph and Model Checking are widely used. However, if the
analyzed Petri net is unbounded then the accessibility graph becomes
infinite and Model Checking can not be used even for small Petri
nets. ECATNets [2] are a category of algebraic Petri nets. The main
feature of ECATNets is their sound and complete semantics based on
rewriting logic [8] and its language Maude [9]. ECATNets analysis
may be done by using techniques of accessibility analysis and Model
Checking defined in Maude. But, these two techniques supported by
Maude do not work also with infinite-states systems. As a category
of Petri nets, ECATNets can be unbounded and so infinite systems.
In order to know if we can apply accessibility analysis and Model
Checking of Maude to an ECATNet, we propose in this paper an
algorithm allowing the detection if the ECATNet is bounded or not.
Moreover, we propose a rewriting logic based tool implementing this
algorithm. We show that the development of this tool using the
Maude system is facilitated thanks to the reflectivity of the rewriting
logic. Indeed, the self-interpretation of this logic allows us both the
modelling of an ECATNet and acting on it.
Abstract: New lead-free ferroelectric relaxor ceramics were
prepared by conventional solid-state synthesis in the BaTiO3-Bi2O3-
Y2O3 systems. Some of these ceramics present a ferroelectric relaxor
with transition temperature close to room temperature. These new
materials are very interesting for applications and can replace leadbased
ceramic to prevent the toxic pollutions during the preparation
state. In the other hand, the energy band diagram shows the
potentiality of these compounds for the solar energy conversion.
Thus, some compositions have been tested successfully for H2
production upon visible light. The best activity occurs in alkaline
media with a rate evolution of about 0.15 mL g-1 mn-1 and a quantum
yield of 1% under polychromatic light.
Abstract: We propose an enhanced key management scheme
based on Key Infection, which is lightweight scheme for tiny sensors.
The basic scheme, Key Infection, is perfectly secure against node
capture and eavesdropping if initial communications after node
deployment is secure. If, however, an attacker can eavesdrop on
the initial communications, they can take the session key. We use
common neighbors for each node to generate the session key. Each
node has own secret key and shares it with its neighbor nodes. Then
each node can establish the session key using common neighbors-
secret keys and a random number. Our scheme needs only a few
communications even if it uses neighbor nodes- information. Without
losing the lightness of basic scheme, it improves the resistance against
eavesdropping on the initial communications more than 30%.
Abstract: This article is devoted to the analysis of results of
sociological researches carried out by authors directed on studying of
opinion of representatives of small, medium and big business on
formation of the Customs Union, Common Free Market Zone with
participation of Kazakhstan, Russia and Belarus.
It-s forecasted that companies, their branches will interpenetrate
with registration and moving their businesses to regions with more
beneficial conditions. They say that in Kazakhstan there are more
profitable geo-strategic operating environment for business and lower
taxes. Russia using this opportunity will create new conditions for
expansion into other countries of Central Asia and China. Opinions
of participants of questionnaire and expert poll different in estimation
of value of these two integration mechanisms since market segments
on the one hand extend, but also on the other hand - loss of exclusive
influence in certain fields of activity.
Abstract: In this paper, a study on the modes of collapse of
compress- expand members are presented. Compress- expand member
is a compact, multiple-combined cylinders, to be proposed as energy
absorbers. Previous studies on the compress- expand member have
clarified its energy absorption efficiency, proposed an approximate
equation to describe its deformation characteristics and also
highlighted the improvement that it has brought. However, for the
member to be practical, the actual range of geometrical dimension that
it can maintain its applicability must be investigated. In this study,
using a virtualized materials that comply the bilinear hardening law,
Finite element Method (FEM) analysis on the collapse modes of
compress- expand member have been conducted. Deformation maps
that plotted the member's collapse modes with regards to the member's
geometric and material parameters were then presented in order to
determine the dimensional range of each collapse modes.