Abstract: In this paper we present a novel approach for human
Body configuration based on the Silhouette. We propose to address
this problem under the Bayesian framework. We use an effective
Model based MCMC (Markov Chain Monte Carlo) method to solve
the configuration problem, in which the best configuration could be
defined as MAP (maximize a posteriori probability) in Bayesian
model. This model based MCMC utilizes the human body model to
drive the MCMC sampling from the solution space. It converses the
original high dimension space into a restricted sub-space constructed
by the human model and uses a hybrid sampling algorithm. We
choose an explicit human model and carefully select the likelihood
functions to represent the best configuration solution. The
experiments show that this method could get an accurate
configuration and timesaving for different human from multi-views.
Abstract: Ethanol is generally used as a therapeutic reagent against Hepatocellular carcinoma (HCC or hepatoma) worldwide, as it can induce Hepatocellular carcinoma cell apoptosis at low concentration through a multifactorial process regulated by several unknown proteins. This paper provides a simple and available proteomic strategy for exploring differentially expressed proteins in the apoptotic pathway. The appropriate concentrations of ethanol required to induce HepG2 cell apoptosis were first assessed by MTT assay, Gisma and fluorescence staining. Next, the central proteins involved in the apoptosis pathway processs were determined using 2D-PAGE, SDS-PAGE, and bio-software analysis. Finally the downregulation of two proteins, AFP and survivin, were determined by immunocytochemistry and reverse transcriptase PCR (RT-PCR) technology. The simple, useful method demonstrated here provides a new approach to proteomic analysis in key bio-regulating process including proliferation, differentiation, apoptosis, immunity and metastasis.
Abstract: This paper reports work done to improve the modeling of complex processes when only small experimental data sets are available. Neural networks are used to capture the nonlinear underlying phenomena contained in the data set and to partly eliminate the burden of having to specify completely the structure of the model. Two different types of neural networks were used for the application of pulping problem. A three layer feed forward neural networks, using the Preconditioned Conjugate Gradient (PCG) methods were used in this investigation. Preconditioning is a method to improve convergence by lowering the condition number and increasing the eigenvalues clustering. The idea is to solve the modified odified problem M-1 Ax= M-1b where M is a positive-definite preconditioner that is closely related to A. We mainly focused on Preconditioned Conjugate Gradient- based training methods which originated from optimization theory, namely Preconditioned Conjugate Gradient with Fletcher-Reeves Update (PCGF), Preconditioned Conjugate Gradient with Polak-Ribiere Update (PCGP) and Preconditioned Conjugate Gradient with Powell-Beale Restarts (PCGB). The behavior of the PCG methods in the simulations proved to be robust against phenomenon such as oscillations due to large step size.
Abstract: We have measured the pressure drop and convective
heat transfer coefficient of water – based AL(25nm),AL2O3(30nm)
and CuO(50nm) Nanofluids flowing through a uniform heated
circular tube in the fully developed laminar flow regime. The
experimental results show that the data for Nanofluids friction factor
show a good agreement with analytical prediction from the Darcy's
equation for single-phase flow. After reducing the experimental
results to the form of Reynolds, Rayleigh and Nusselt numbers. The
results show the local Nusselt number and temperature have
distribution with the non-dimensional axial distance from the tube
entry. Study decided that thenNanofluid as Newtonian fluids through
the design of the linear relationship between shear stress and the rate
of stress has been the study of three chains of the Nanofluid with
different concentrations and where the AL, AL2O3 and CuO – water
ranging from (0.25 - 2.5 vol %). In addition to measuring the four
properties of the Nanofluid in practice so as to ensure the validity of
equations of properties developed by the researchers in this area and
these properties is viscosity, specific heat, and density and found that
the difference does not exceed 3.5% for the experimental equations
between them and the practical. The study also demonstrated that the
amount of the increase in heat transfer coefficient for three types of
Nano fluid is AL, AL2O3, and CuO – Water and these ratios are
respectively (45%, 32%, 25%) with insulation and without insulation
(36%, 23%, 19%), and the statement of any of the cases the best
increase in heat transfer has been proven that using insulation is
better than not using it. I have been using three types of Nano
particles and one metallic Nanoparticle and two oxide Nanoparticle
and a statement, whichever gives the best increase in heat transfer.
Abstract: PCCI engines can reduce NOx and PM emissions
simultaneously without sacrificing thermal efficiency, but a low
combustion temperature resulting from early fuel injection, and
ignition occurring prior to TDC, can cause higher THC and CO
emissions and fuel consumption. In conclusion, it was found that the
PCCI combustion achieved by the 2-stage injection strategy with
optimized calibration factors (e.g. EGR rate, injection pressure, swirl
ratio, intake pressure, injection timing) can reduce NOx and PM
emissions simultaneously. This research works are expected to
provide valuable information conducive to a development of an
innovative combustion engine that can fulfill upcoming stringent
emission standards.
Abstract: 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonate using NADPH and the enzyme is involved in rate-controlling step of mevalonate. Inhibition of HMGR is considered as effective way to lower cholesterol levels so it is drug target to treat hypercholesterolemia, major risk factor of cardiovascular disease. To discover novel HMGR inhibitor, we performed structure-based pharmacophore modeling combined with molecular dynamics (MD) simulation. Four HMGR inhibitors were used for MD simulation and representative structure of each simulation were selected by clustering analysis. Four structure-based pharmacophore models were generated using the representative structure. The generated models were validated used in virtual screening to find novel scaffolds for inhibiting HMGR. The screened compounds were filtered by applying drug-like properties and used in molecular docking. Finally, four hit compounds were obtained and these complexes were refined using energy minimization. These compounds might be potential leads to design novel HMGR inhibitor.
Abstract: The problem of robust stability and robust stabilization for a class of discrete-time uncertain systems with time delay is investigated. Based on Tchebychev inequality, by constructing a new augmented Lyapunov function, some improved sufficient conditions ensuring exponential stability and stabilization are established. These conditions are expressed in the forms of linear matrix inequalities (LMIs), whose feasibility can be easily checked by using Matlab LMI Toolbox. Compared with some previous results derived in the literature, the new obtained criteria have less conservatism. Two numerical examples are provided to demonstrate the improvement and effectiveness of the proposed method.
Abstract: The effect of extraction solvent upon properties
of carrageenan from Eucheuma cottonii was studied. The
distilled water and KOH solution (concentration 0.1- 0.5N) were
used as the solvent. Extraction process was carried out in water
bath equipped by stirrer with constant speed of 275 rpm with a
constant ratio of seaweed weight to solvent volume ( 1:50 g/mL)
at 86oC for 45 minutes. The extract was then precipitated in 3
volume of 90% ethanol, oven dried at 60oC. Based on
experimental data, alkali significantly influenced yield and
properties of extracted carrageenan. The extracted carrageenan
was found to have essentially identical FTIR spectra to the
reference samples of kappa-carrageenan. Increasing the KOH
concentration led to carrageenan containing less sulfate content
and intrinsic viscosity. The gel strength increased along with the
increasing of KOH concentration. The decreasing of intrinsic
viscosity value indicates that a polymer degradation occurs
during alkali extraction.
Abstract: In single trial analysis, when using Principal
Component Analysis (PCA) to extract Visual Evoked Potential
(VEP) signals, the selection of principal components (PCs) is an
important issue. We propose a new method here that selects only
the appropriate PCs. We denote the method as selective eigen-rate
(SER). In the method, the VEP is reconstructed based on the rate
of the eigen-values of the PCs. When this technique is applied on
emulated VEP signals added with background
electroencephalogram (EEG), with a focus on extracting the
evoked P3 parameter, it is found to be feasible. The improvement
in signal to noise ratio (SNR) is superior to two other existing
methods of PC selection: Kaiser (KSR) and Residual Power (RP).
Though another PC selection method, Spectral Power Ratio (SPR)
gives a comparable SNR with high noise factors (i.e. EEGs), SER
give more impressive results in such cases. Next, we applied SER
method to real VEP signals to analyse the P3 responses for
matched and non-matched stimuli. The P3 parameters extracted
through our proposed SER method showed higher P3 response for
matched stimulus, which confirms to the existing neuroscience
knowledge. Single trial PCA using KSR and RP methods failed to
indicate any difference for the stimuli.
Abstract: The P-Bigram method is a string comparison methods
base on an internal two characters-based similarity measure. The edit
distance between two strings is the minimal number of elementary
editing operations required to transform one string into the other. The
elementary editing operations include deletion, insertion, substitution
two characters. In this paper, we address the P-Bigram method to
sole the similarity problem in DNA sequence. This method provided
an efficient algorithm that locates all minimum operation in a string.
We have been implemented algorithm and found that our program
calculated that smaller distance than one string. We develop PBigram
edit distance and show that edit distance or the similarity and
implementation using dynamic programming. The performance of
the proposed approach is evaluated using number edit and percentage
similarity measures.
Abstract: Chronic conditions carry with them strong emotions
and often lead to charged relationships between patients and their
health providers and, by extension, patients and health researchers.
Persons are both autonomous and relational and a purely cognitive
model of autonomy neglects the social and relational basis of chronic
illness. Ensuring genuine informed consent in research requires a
thorough understanding of how participants perceive a study and
their reasons for participation. Surveys may not capture the
complexities of reasoning that underlies study participation.
Contradictory reasons for participation, for instance an initial claim
of altruism as rationale and a subsequent claim of personal benefit
(therapeutic misconception), affect the quality of informed consent.
Individuals apply principles through the filter of personal values and
lived experience. Authentic autonomy, and hence authentic consent
to research, occurs within the context of patients- unique life
narratives and illness experiences.
Abstract: In this paper we propose a family of algorithms based
on 3rd and 4th order cumulants for blind single-input single-output
(SISO) Non-Minimum Phase (NMP) Finite Impulse Response (FIR)
channel estimation driven by non-Gaussian signal. The input signal
represents the signal used in 10GBASE-T (or IEEE 802.3an-2006)
as a Tomlinson-Harashima Precoded (THP) version of random
Pulse-Amplitude Modulation with 16 discrete levels (PAM-16). The
proposed algorithms are tested using three non-minimum phase
channel for different Signal-to-Noise Ratios (SNR) and for different
data input length. Numerical simulation results are presented to
illustrate the performance of the proposed algorithms.
Abstract: Grid composite structures have many applications in aerospace industry in which deal with transverse loadings abundantly. In present paper a stiffened composite cylindrical shell with clamped-free boundary condition under transverse end load experimentally and numerically was studied. Some electrical strain gauges were employed to measure the strains. Also a finite element analysis was done for validation of experimental result. The FEM software used was ANSYS11. In addition, the results between stiffened composite shell and unstiffened composite shell were compared. It was observed that intersection of two stiffeners has an important effect in decrease of stress in the shell. Fairly good agreements were observed between the numerical and the measured results. According to recent studies about grid composite structures, it should be noted that any investigation like this research has not been reported.
Abstract: In any distributed systems, process scheduling plays a
vital role in determining the efficiency of the system. Process scheduling algorithms are used to ensure that the components of the
system would be able to maximize its utilization and able to complete all the processes assigned in a specified period of time.
This paper focuses on the development of comparative simulator for distributed process scheduling algorithms. The objectives of the works that have been carried out include the development of the
comparative simulator, as well as to implement a comparative study
between three distributed process scheduling algorithms; senderinitiated,
receiver-initiated and hybrid sender-receiver-initiated
algorithms. The comparative study was done based on the Average Waiting Time (AWT) and Average Turnaround Time (ATT) of the
processes involved. The simulation results show that the performance of the algorithms depends on the number of nodes in the system.
Abstract: System MEMORI automatically detects and recognizes rotated and/or rescaled versions of the objects of a database within digital color images with cluttered background. This task is accomplished by means of a region grouping algorithm guided by heuristic rules, whose parameters concern some geometrical properties and the recognition score of the database objects. This paper focuses on the strategies implemented in MEMORI for the estimation of the heuristic rule parameters. This estimation, being automatic, makes the system a highly user-friendly tool.
Abstract: In Korea, the technology of a load fo nuclear power plant has been being developed.
automatic controller which is able to control temperature and axial power distribution was developed. identification algorithm and a model predictive contact former transforms the nuclear reactor status into
numerically. And the latter uses them and ge
manipulated values such as two kinds of control ro
this automatic controller, the performance of a coperation was evaluated. As a result, the automatic generated model parameters of a nuclear react to nuclear reactor average temperature and axial power the desired targets during a daily load follow.
Abstract: The flash memory has many advantages such as low power consumption, strong shock resistance, fast I/O and non-volatility. And it is increasingly used in the mobile storage device. The YAFFS, one of the NAND flash file system, is widely used in the embedded device. However, the existing YAFFS takes long time to mount the file system because it scans whole spare areas in all pages of NAND flash memory. In order to solve this problem, we propose a new content-based flash file system using a mounting time reduction technique. The proposed method only scans partial spare areas of some special pages by using content-based block management. The experimental results show that the proposed method reduces the average mounting time by 87.2% comparing with JFFS2 and 69.9% comparing with YAFFS.
Abstract: All around the world pulp and paper industries are the
biggest plant production with the environmental pollution as the
biggest challenge facing the pulp manufacturing operations. The
concern among these industries is to produce a high volume of papers
with the high quality standard and of low cost without affecting the
environment. This result obtained from this bleaching study show
that the activation of peroxide was an effective method of reducing
the total applied charge of chlorine dioxide which is harmful to our
environment and also show that softwood and hardwood Kraft pulps
responded linearly to the peroxide treatments. During the bleaching
process the production plant produce chlorines. Under the trial stages
chloride dioxide has been reduced by 3 kg/ton to reduce the
brightness from 65% ISO to 60% ISO of pulp and the dosing point
returned to the E stage charges by pre-treating Kraft pulps with
hydrogen peroxide. The pulp and paper industry has developed
elemental chlorine free (ECF) and totally chlorine free (TCF)
bleaching, in their quest for being environmental friendly, they have
been looking at ways to turn their ECF process into a TCF process
while still being competitive. This prompted the research to
investigate the capability of the hydrogen peroxide as catalyst to
reduce chloride dioxide.
Abstract: The previous study of new metal gasket that contact
width and contact stress an important design parameter for optimizing
metal gasket performance. The optimum design based on an elastic
and plastic contact stress was founded. However, the influence of
flange surface roughness had not been investigated thoroughly. The
flange has many kinds of surface roughness. In this study, we
conducted a gasket model include a flange surface roughness effect. A
finite element method was employed to develop simulation solution. A
uniform quadratic mesh used for meshing the gasket material and a
gradually quadrilateral mesh used for meshing the flange. The gasket
model was simulated by using two simulation stages which is forming
and tightening simulation. A simulation result shows that a smoother
of surface roughness has higher slope for force per unit length. This
mean a squeezed against between flange and gasket will be strong. The
slope of force per unit length for gasket 400-MPa mode was higher
than the gasket 0-MPa mode.
Abstract: IEEE has recently incorporated CCMP protocol to provide robust security to IEEE 802.11 wireless LANs. It is found that CCMP has been designed with a weak nonce construction and transmission mechanism, which leads to the exposure of initial counter value. This weak construction of nonce renders the protocol vulnerable to attacks by intruders. This paper presents how the initial counter can be pre-computed by the intruder. This vulnerability of counter block value leads to pre-computation attack on the counter mode encryption of CCMP. The failure of the counter mode will result in the collapse of the whole security mechanism of 802.11 WLAN.