Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: The current study focuses on the seismic design of
offshore pipelines against active faults. After an extensive literature
review of the provisions of the seismic norms worldwide and of the
available analytical methods, the study simulates numerically
(through finite-element modeling and strain-based criteria) the
distress of offshore pipelines subjected to PGDs induced by active
normal and reverse seismic faults at the seabed. Factors, such as the
geometrical properties of the fault, the mechanical properties of the
ruptured soil formations, and the pipeline characteristics, are
examined. After some interesting conclusions regarding the seismic
vulnerability of offshore pipelines, potential cost-effective mitigation
measures are proposed taking into account constructability issues.
Abstract: Annihilations, phase shifts, scattering lengths and
elastic cross sections of low energy positrons scattering from
magnesium atoms were studied using the least-squares variational
method (LSVM). The possibility of positron binding to the
magnesium atoms is investigated. A trial wave function is suggested
to represent e+-Mg elastic scattering and scattering parameters were
derived to estimate the binding energy and annihilation rates. The
trial function is taken to depend on several adjustable parameters, and
is improved iteratively by increasing the number of terms. The
present results have the same behavior as reported semi-empirical,
theoretical and experimental results. Especially, the estimated
positive scattering length supports the possibility of positronmagnesium
bound state system that was confirmed in previous
experimental and theoretical work.
Abstract: In this paper, we describe an application for face
recognition. Many studies have used local descriptors to characterize
a face, the performance of these local descriptors remain low by
global descriptors (working on the entire image). The application of
local descriptors (cutting image into blocks) must be able to store
both the advantages of global and local methods in the Discrete
Cosine Transform (DCT) domain. This system uses neural network
techniques. The letter method provides a good compromise between
the two approaches in terms of simplifying of calculation and
classifying performance. Finally, we compare our results with those
obtained from other local and global conventional approaches.
Abstract: The measurement of organ radiation exposure dose is
one of the most important steps to be taken initially, for developing a
new radiopharmaceutical. In this study, the dosimetric studies of a
novel agent for SPECT-imaging of the bone metastasis, 111In-
1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic
acid (111In-DOTMP) complex, have been carried out to estimate the
dose in human organs based on the data derived from rats. The
radiolabeled complex was prepared with high radiochemical purity in
the optimal conditions. Biodistribution studies of the complex was
investigated in the male Syrian rats at selected times after injection
(2, 4, 24 and 48 h). The human absorbed dose estimation of the
complex was made based on data derived from the rats by the
radiation absorbed dose assessment resource (RADAR) method.
111In-DOTMP complex was prepared with high radiochemical purity
of >99% (ITLC). Total body effective absorbed dose for 111In-
DOTMP was 0.061 mSv/MBq. This value is comparable to the other
111In clinically used complexes. The results show that the dose with
respect to the critical organs is satisfactory within the acceptable
range for diagnostic nuclear medicine procedures. Generally, 111In-
DOTMP has interesting characteristics and can be considered as a
viable agent for SPECT-imaging of the bone metastasis in the near
future.
Abstract: Here, we have shown the reaction of [Cr(ArN(CH2)3NAr)2Cl2] (1) where (Ar = 2,6-Pri
2C6H3) and in presence of NaCp (2) (Cp= C5H5 = cyclopentadien), with a center
coordination η5 interaction between Cp as co-ligand and chromium
metal center, for optimization we used density functional theory
(DFT), under methods, explicitly including electrons correlations, for
the final calculations as MB3LYP (Becke) (Lee–Yang–Parr) level of
theory we used to obtain more exact results. This complex was
calculated as electronic energy for molecular system, because the
calculation accounting all electrons correlations interactions. The
optimised of [Cr(ArN(CH2)3NAr)2(η5-Cp)] (Ar = 2,6-Pri2C6H3 and Cp = C5H5) was found to be thermally stable. By using Dewar-Chatt-Duncanson model, as a basis of the molecular orbital (MO) analysis
and showed the highest occupied molecular orbital (HOMO) and
lowest occupied molecular orbital LUMO.
Abstract: This study, tries to suggest a design method based on
displacement using finite difference numerical modeling in
reinforcing soil retaining wall with steel strip. In this case, dynamic
loading characteristics such as duration, frequency, peak ground
acceleration, geometrical characteristics of reinforced soil structure
and type of the site are considered to correct the pseudo static method
and finally introduce the pseudo static coefficient as a function of
seismic performance level and peak ground acceleration. For this
purpose, the influence of dynamic loading characteristics,
reinforcement length, height of reinforced system and type of the site
are investigated on seismic behavior of reinforcing soil retaining wall
with steel strip. Numerical results illustrate that the seismic response
of this type of wall is highly dependent to cumulative absolute
velocity, maximum acceleration, and height and reinforcement length
so that the reinforcement length can be introduced as the main factor
in shape of failure. Considering the loading parameters, geometric parameters of the
wall and type of the site showed that the used method in this study
leads to efficient designs in comparison with other methods, which
are usually based on limit-equilibrium concept. The outputs show the
over-estimation of equilibrium design methods in comparison with
proposed displacement based methods here.
Abstract: The present study examined how translation teachers
develop final tests as measures for checking on the quality of
students’ academic translation in Iranian context. To achieve this
goal, thirty experienced male and female translation teachers from the
four types of the universities offering the program were invited to an
in-depth 30-minute one-session semi-structured interview. The
responses provided showed how much discrepancy exists among the
Iranian translation teachers (as developers of final translation tests),
who are least informed with the current translation evaluation
methods. It was also revealed that the criteria they use for developing
such tests and scoring student translations are not theory-driven but
are highly subjective, mainly based on their personal experience and
intuition. Hence, the quality and accountability of such tests are under
serious question. The results also confirmed that the dominant
method commonly and currently practiced is the purely essay-type
format. To remedy the situation, some suggestions are in order. As
part of the solution, to improve the reliability and validity of such
tests, the present summative, product-oriented evaluation should be
accompanied with some formative, process-oriented methods of
evaluation. Training the teachers and helping them get acquainted
with modern principles of translation evaluation as well as the
existing models, and rating scales does improve the quality of
academic translation evaluation.
Abstract: Modelling of building processes of a multimodal
freight transportation support information system is discussed based
on modern CASE technologies. Functional efficiencies of ports in
the eastern part of the Black Sea are analyzed taking into account
their ecological, seasonal, resource usage parameters. By resources,
we mean capacities of berths, cranes, automotive transport, as well as
work crews and neighbouring airports. For the purpose of designing
database of computer support system for Managerial (Logistics)
function, using Object-Role Modeling (ORM) tool (NORMA–Natural ORM Architecture) is proposed, after which Entity
Relationship Model (ERM) is generated in automated process.
Software is developed based on Process-Oriented and Service-Oriented architecture, in Visual Studio.NET environment.
Abstract: In the last decade the emergence of new social needs
as an effect of the economic crisis has stimulated the flourishing of
business endeavours characterised by explicit social goals. Social
start-ups, social enterprises or Corporate Social Responsibility
operations carried out by traditional companies are quintessential
examples in this regard. This paper analyses these kinds of initiatives
in order to discover the main characteristics of social business models
and to provide insights to social entrepreneurs for developing or
improving their strategies. The research is conducted through the
integration of literature review and case study analysis and, thanks to
the recognition of the importance of both profits and social impacts
as the key success factors for a social business model, proposes a
framework for identifying indicators suitable for measuring the social
impacts generated.
Abstract: Carbon Fiber Reinforced Plastics (CFRPs) are widely
used for advanced applications, in particular in aerospace, automotive
and wind energy industries. Once cured to near net shape, CFRP
parts need several finishing operations such as trimming, milling or
drilling in order to accommodate fastening hardware and meeting the
final dimensions. The present research aims to study the effect of the
cutting temperature in trimming on the mechanical strength of high
performance CFRP laminates used for aeronautics applications. The
cutting temperature is of great importance when dealing with
trimming of CFRP. Temperatures higher than the glass-transition
temperature (Tg) of the resin matrix are highly undesirable: they
cause degradation of the matrix in the trimmed edges area, which can
severely affect the mechanical performance of the entire component.
In this study, a 9.50mm diameter CVD diamond coated carbide tool
with six flutes was used to trim 24-plies CFRP laminates. A
300m/min cutting speed and 1140mm/min feed rate were used in the
experiments. The tool was heated prior to trimming using a
blowtorch, for temperatures ranging from 20°C to 300°C. The
temperature at the cutting edge was measured using embedded KType
thermocouples. Samples trimmed for different cutting
temperatures, below and above Tg, were mechanically tested using
three-points bending short-beam loading configurations. New cutting
tools as well as worn cutting tools were utilized for the experiments.
The experiments with the new tools could not prove any correlation
between the length of cut, the cutting temperature and the mechanical
performance. Thus mechanical strength was constant, regardless of
the cutting temperature. However, for worn tools, producing a cutting
temperature rising up to 450°C, thermal damage of the resin was
observed. The mechanical tests showed a reduced mean resistance in
short beam configuration, while the resistance in three point bending
decreases with increase of the cutting temperature.
Abstract: In recent years, the power system has been changed
and a flexible power pricing system such as demand response has been
sought in Japan. The demand response system works simply in the
household sector and the owner as the decision-maker, can benefit
from power saving. On the other hand, the execution of demand
response in the office building is more complex than in the household
because various people such as owners, building administrators and
occupants are involved in the decision-making process. While the
owners benefit from demand saving, the occupants are exposed to
restricted benefits of a demand-saved environment. One of the reasons
is that building systems are usually under centralized management and
each occupant cannot choose freely whether to participate in demand
response or not. In addition, it is unclear whether incentives give
occupants the motivation to participate. However, the recent
development of IT and building systems enables the personalized
control of the office environment where each occupant can control the
lighting level or temperature individually. Therefore, it can be possible
to have a system which each occupant can make a decision of whether
or not to participate in demand response in the office building. This study investigates personal responses to demand response
requests, under the condition where each occupant can adjust their
brightness individually in their workspace. Once workers participate
in the demand response, their desk-lights are automatically turned off.
The participation rates in the demand response events are compared
among four groups, which are divided by different motivation, the
presence, or absence of incentives and the method of participation. The
result shows that there are significant differences of participation rates
in demand response event between four groups. The method of
participation has a large effect on the participation rate. The “Opt-out”
groups where the occupants are automatically enrolled in a demand
response event if they do not express non-participation have the
highest participation rate in the four groups. Incentives also have an
effect on the participation rate. This study also reports on the impact of low illumination office
environment on the occupants, such as stress or fatigue. The
electrocardiogram and the questionnaire are used to investigate the
autonomic nervous activity and subjective fatigue symptoms of the
occupants. There is no big difference between dim workspace during
demand response event and bright workspace in autonomic nervous
activity and fatigue.
Abstract: The first layer of defense against data loss is the backup
data. This paper implements an agent-based network backup system
used the backup, server-storage and server-backup agent these
tripartite construction, and the snapshot and hierarchical index are
used in the NSBS. It realizes the control command and data flow
separation, balances the system load, thereby improving efficiency of
the system backup and recovery. The test results show the agent-based
network backup system can effectively improve the task-based
concurrency, reasonably allocate network bandwidth, the system
backup performance loss costs smaller and improves data recovery
efficiency by 20%.
Abstract: The reheating furnace is used to reheat the steel slabs
before the hot-rolling process. The supported system includes the
stationary/moving beams, and the skid buttons which block some
thermal radiation transmitted to the bottom of the slabs. Therefore, it is
important to analyze the steel slab temperature distribution during the
heating period. A three-dimensional mathematical transient heat
transfer model for the prediction of temperature distribution within the
slab has been developed. The effects of different skid button height
(H=60mm, 90mm, and 120mm) and different gap distance between
two slabs (S=50mm, 75mm, and 100mm) on the slab skid mark
formation and temperature profiles are investigated. Comparison with
the in-situ experimental data from Steel Company in Taiwan shows
that the present heat transfer model works well for the prediction of
thermal behavior of the slab in the reheating furnace. It is found that
the skid mark severity decreases with an increase in the skid button
height. The effect of gap distance is important only for the slab edge
planes, while it is insignificant for the slab central planes.
Abstract: The market competition is moving from the single
firm to the whole supply chain because of increasing competition and
growing need for operational efficiencies and customer orientation.
Supply chain management allows companies to look beyond their
organizational boundaries to develop and leverage resources and
capabilities of their supply chain partners. This creates competitive
advantages in the marketplace and because of this SCM has acquired
strategic importance. Lean Approach is a management strategy that focuses on reducing
every type of waste present in an organization. This approach is
becoming more and more popular among supply chain managers. The supply chain application of lean approach is not frequent. In
particular, it is not well studied which are the impacts of lean
approach principles in a supply chain context. In literature there are
only few studies aimed at understanding the qualitative impact of the
lean approach in supply chains. Therefore, the goal of this research
work is to study the impacts of lean principles implementation along
a supply chain. To achieve this, a simulation model of a threeechelon
multi-product supply chain has been built. Kanban system (and several priority policies) and setup time
reduction degrees are implemented in the lean-configured supply
chain to apply pull and lot-sizing decrease principles respectively. To
evaluate the benefits of lean approach, lean supply chain is compared
with an EOQ-configured supply chain. The simulation results show
that Kanban system and setup-time reduction improve inventory
stock level. They also show that logistics efforts are affected to lean
implementation degree. The paper concludes describing
performances of lean supply chain in different contexts.
Abstract: Zinc borate is an important inorganic hydrate borate
material, which can be used as a flame retardant agent and corrosion
resistance material. This compound can loss its structural water
content at higher than 290°C. Due to thermal stability; Zinc Borate
can be used as flame retardant at high temperature process of plastic
and gum. In this study, the ultrasonic reaction of zinc borates were
studied using hydrozincite (Zn5(CO3)2·(OH)6) and boric acid
(H3BO3) raw materials. Before the synthesis raw materials were
characterized by X-Ray Diffraction (XRD) and Fourier Transform
Infrared Spectroscopy (FT-IR). Ultrasonic method is a new
application on the zinc borate synthesis. The synthesis parameters
were set to 90°C reaction temperature and 55 minutes of reaction
time, with 1:1, 1:2, 1:3, 1:4 and 1:5 molar ratio of starting materials
(Zn5(CO3)2·(OH)6 : H3BO3). After the zinc borate synthesis, the
products were analyzed by XRD and FT-IR. As a result, optimum
molar ratio of 1:5 is determined for the synthesis of zinc borates with
ultrasonic method.
Abstract: This paper tries to answer to the questions whether or
not trade openness causes economic growth and trade policy changes
are good for Turkey as a developing country in global economy
before and after 1980. We employ Johansen co-integration and
Granger causality tests with error correction modeling based on
vector autoregressive. Using WDI data from the pre-1980 and the
post-1980, we find that trade openness and economic growth are cointegrated
in the second term only. Also the results suggest a lack of
long-run causality between our two variables. These findings may
imply that trade policy of Turkey should concentrate more on extra
complementary economic reforms.
Abstract: Natural admixtures provide concrete with enhanced
properties but their processing end up making them very expensive
resulting in increase to cost of concrete. In this study the effect
of Gum from Acacia Karroo (GAK) as set-retarding admixture
in cement pastes was studied. The possibility of using GAK as
water reducing admixture both in cement mortar concrete was
also investigated. Cement pastes with different dosages of GAK
were prepared to measure the setting time using different dosages.
Compressive strength of cement mortars with 0.7, 0.8 and 0.9%
weight of cement and w/c ratio of 0.5 were compared to those with
water cement (w/c) ratio of 0.44 but same dosage of GAK. Concrete
samples were prepared using higher dosages of GAK (1, 2 and 3%
wt of cement) and a water bidder (w/b) of 0.61 were compared to
those with the same GAK dosage but with reduced w/b ratio. There
was increase in compressive strength of 9.3% at 28 days for cement
mortar samples with 0.9% dosage of GAK and reduced w/c ratio.
Abstract: Cortisol is essential to the regulation of the immune
system and pathological yawning is a symptom of multiple sclerosis
(MS). Electromyography activity (EMG) in the jaw muscles typically
rises when the muscles are moved – extended or flexed; and yawning
has been shown to be highly correlated with cortisol levels in healthy
people as shown in the Thompson Cortisol Hypothesis. It is likely
that these elevated cortisol levels are also seen in people with MS.
The possible link between EMG in the jaw muscles and rises in saliva
cortisol levels during yawning were investigated in a randomized
controlled trial of 60 volunteers aged 18-69 years who were exposed
to conditions that were designed to elicit the yawning response.
Saliva samples were collected at the start and after yawning, or at the
end of the presentation of yawning-provoking stimuli, in the absence
of a yawn, and EMG data was additionally collected during rest and
yawning phases. Hospital Anxiety and Depression Scale, Yawning
Susceptibility Scale, General Health Questionnaire, demographic,
and health details were collected and the following exclusion criteria
were adopted: chronic fatigue, diabetes, fibromyalgia, heart
condition, high blood pressure, hormone replacement therapy,
multiple sclerosis, and stroke. Significant differences were found
between the saliva cortisol samples for the yawners, t (23) = -4.263, p
= 0.000, as compared with the non-yawners between rest and poststimuli,
which was non-significant. There were also significant
differences between yawners and non-yawners for the EMG
potentials with the yawners having higher rest and post-yawning
potentials. Significant evidence was found to support the Thompson
Cortisol Hypothesis suggesting that rises in cortisol levels are
associated with the yawning response. Further research is underway
to explore the use of cortisol as a potential diagnostic tool as an assist
to the early diagnosis of symptoms related to neurological disorders.
Bournemouth University Research & Ethics approval granted:
JC28/1/13-KA6/9/13. Professional code of conduct, confidentiality,
and safety issues have been addressed and approved in the Ethics
submission. Trials identification number: ISRCTN61942768.
http://www.controlled-trials.com/isrctn/
Abstract: In this talk, we introduce a newly developed quantile
function model that can be used for estimating conditional
distributions of financial returns and for obtaining multi-step ahead
out-of-sample predictive distributions of financial returns. Since we
forecast the whole conditional distributions, any predictive quantity
of interest about the future financial returns can be obtained simply
as a by-product of the method. We also show an application of the
model to the daily closing prices of Dow Jones Industrial Average
(DJIA) series over the period from 2 January 2004 - 8 October 2010.
We obtained the predictive distributions up to 15 days ahead for
the DJIA returns, which were further compared with the actually
observed returns and those predicted from an AR-GARCH model.
The results show that the new model can capture the main features
of financial returns and provide a better fitted model together with
improved mean forecasts compared with conventional methods. We
hope this talk will help audience to see that this new model has the
potential to be very useful in practice.