Abstract: Reverse engineering of full-genomic interaction networks based on compendia of expression data has been successfully applied for a number of model organisms. This study adapts these approaches for an important non-model organism: The major human fungal pathogen Candida albicans. During the infection process, the pathogen can adapt to a wide range of environmental niches and reversibly changes its growth form. Given the importance of these processes, it is important to know how they are regulated. This study presents a reverse engineering strategy able to infer fullgenomic interaction networks for C. albicans based on a linear regression, utilizing the sparseness criterion (LASSO). To overcome the limited amount of expression data and small number of known interactions, we utilize different prior-knowledge sources guiding the network inference to a knowledge driven solution. Since, no database of known interactions for C. albicans exists, we use a textmining system which utilizes full-text research papers to identify known regulatory interactions. By comparing with these known regulatory interactions, we find an optimal value for global modelling parameters weighting the influence of the sparseness criterion and the prior-knowledge. Furthermore, we show that soft integration of prior-knowledge additionally improves the performance. Finally, we compare the performance of our approach to state of the art network inference approaches.
Abstract: In this paper a controller for the pitch angle of an
aircraft regarding to the elevator deflection angle is designed.
The way how the elevator angle affects pitching motion of the
aircraft is pointed out, as well as, how a pitch controller can be
applied for the aircraft to reach certain pitch angle. In this digital
optimal system, the elevator deflection angle and pitching angle
of the plane are considered to be input and output respectively.
A single input single output (SISO) system is presented. A
digital pitch aircraft control is demonstrated. A simulation for
the whole system has been performed. The optimal control
weighting vectors, Q and R have been determined.
Abstract: There are different kinds of online systems on the Internet for people who need support and develop new knowledge. Online communities and Ask the Expert systems are two such systems. In the health care area, the number of users of these systems has increased at a rapid pace. Interactions with medical trained experts take place online, and people with concerns about similar health problems come together to share experiences and advice. The systems are also used as storages and browsed for health information. Over the years, studies have been conducted of the usage of the different systems. However, in what ways the systems can be used together to enhance learning has not been explored. This paper presents results from a study of online health-communities and an Ask the Expert system for people who suffer from overweight. Differences and similarities in regards to posted issues and replies are discussed, and suggestions for a new holistic design of the two systems are presented.
Abstract: This work proposes a recursive weighted ELS
algorithm for system identification by applying numerically robust
orthogonal Householder transformations. The properties of the
proposed algorithm show it obtains acceptable results in a noisy
environment: fast convergence and asymptotically unbiased
estimates. Comparative analysis with others robust methods well
known from literature are also presented.
Abstract: In this paper an approaches for increasing the
effectiveness of error detection in computer network channels with
Pulse-Amplitude Modulation (PAM) has been proposed. Proposed
approaches are based on consideration of special feature of errors,
which are appearances in line with PAM. The first approach consists
of CRC modification specifically for line with PAM. The second
approach is base of weighted checksums using. The way for
checksum components coding has been developed. It has been shown
that proposed checksum modification ensure superior digital data
control transformation reliability for channels with PAM in compare
to CRC.
Abstract: The experiment was then conducted to investigate the
effect of cassava peel addition in the concentrate on the performance
of lactating dairy cows. Twenty four Holstein Friesian crossbred
(>87.5% Holstein Friesian) lactating dairy cows in mid lactation;
averaging 12.2+2.1 kg of milk, 119+45 days in milk, 44.1+6.2
months old and 449+33 kg live weight, were stratified for milk yield,
days in milk, age, stage of lactation and body weight, and then
randomly allocated to three treatment groups. The first, second and
third groups were fed concentrates containing the respective cassava
peel, 0, 20 and 40%. All cows were fed ad libitum corn silage and
freely access to clean water. Dry matter intake, 4%FCM, milk
composition and body weight change were affected (P
Abstract: Self-compacting concrete (SCC), a new kind of high
performance concrete (HPC) have been first developed in Japan in
1986. The development of SCC has made casting of dense
reinforcement and mass concrete convenient, has minimized noise.
Fresh self-compacting concrete (SCC) flows into formwork and
around obstructions under its own weight to fill it completely and
self-compact (without any need for vibration), without any
segregation and blocking. The elimination of the need for
compaction leads to better quality concrete and substantial
improvement of working conditions. SCC mixes generally have a
much higher content of fine fillers, including cement, and produce
excessively high compressive strength concrete, which restricts its
field of application to special concrete only. To use SCC mixes in
general concrete construction practice, requires low cost materials to
make inexpensive concrete.
Rice husk ash (RHA) has been used as a highly reactive
pozzolanic material to improve the microstructure of the interfacial
transition zone (ITZ) between the cement paste and the aggregate in
self compacting concrete. Mechanical experiments of RHA blended
Portland cement concretes revealed that in addition to the pozzolanic
reactivity of RHA (chemical aspect), the particle grading (physical
aspect) of cement and RHA mixtures also exerted significant
influences on the blending efficiency.
The scope of this research was to determine the usefulness of Rice
husk ash (RHA) in the development of economical self compacting
concrete (SCC). The cost of materials will be decreased by reducing
the cement content by using waste material like rice husk ash instead
of.
This paper presents a study on the development of Mechanical
properties up to 180 days of self compacting and ordinary concretes
with rice-husk ash (RHA), from a rice paddy milling industry in
Rasht (Iran). Two different replacement percentages of cement by
RHA, 10%, and 20%, and two different water/cementicious material
ratios (0.40 and 0.35), were used for both of self compacting and
normal concrete specimens. The results are compared with those of
the self compacting concrete without RHA, with compressive,
flexural strength and modulus of elasticity. It is concluded that RHA
provides a positive effect on the Mechanical properties at age after
60 days.
Base of the result self compacting concrete specimens have higher
value than normal concrete specimens in all test except modulus of
elasticity. Also specimens with 20% replacement of cement by RHA
have the best performance.
Abstract: The forest stand consisted of four layers. The species
composition between the third and the bottom layers was almost
similar, whereas it was almost exclusive between the top and the lower
three layers. The values of Shannon-s index H' and Pielou-s index
J ' tended to increase from the bottom layer upward, except for
H' -value of the top layer. The values of H' and J ' were 4.21 bit
and 0.73, respectively, for the total stand. High woody species
diversity of the forest depended on large trees in the upper layers,
which trend was different from a subtropical evergreen broadleaf
forest grown in silicate habitat in the northern part of Okinawa Island.
The spatial distribution of trees was overlapped between the third and
the bottom layers, whereas it was independent or slightly exclusive
between the top and the lower three layers. Mean tree weight of each
layer decreased from the top toward the bottom layer, whereas the
corresponding tree density increased from the top downward. This
relationship was analogous to the process of self-thinning plant
populations.
Abstract: We study the performance of compressed beamforming
weights feedback technique in generalized triangular decomposition
(GTD) based MIMO system. GTD is a beamforming technique that
enjoys QoS flexibility. The technique, however, will perform at its
optimum only when the full knowledge of channel state information
(CSI) is available at the transmitter. This would be impossible in
the real system, where there are channel estimation error and limited
feedback. We suggest a way to implement the quantized beamforming
weights feedback, which can significantly reduce the feedback data,
on GTD-based MIMO system and investigate the performance of
the system. Interestingly, we found that compressed beamforming
weights feedback does not degrade the BER performance of the
system at low input power, while the channel estimation error
and quantization do. For comparison, GTD is more sensitive to
compression and quantization, while SVD is more sensitive to the
channel estimation error. We also explore the performance of GTDbased
MU-MIMO system, and find that the BER performance starts
to degrade largely at around -20 dB channel estimation error.
Abstract: Recently, the findings on the MEG iterative scheme has demonstrated to accelerate the convergence rate in solving any system of linear equations generated by using approximation equations of boundary value problems. Based on the same scheme, the aim of this paper is to investigate the capability of a family of four-point block iterative methods with a weighted parameter, ω such as the 4 Point-EGSOR, 4 Point-EDGSOR, and 4 Point-MEGSOR in solving two-dimensional elliptic partial differential equations by using the second-order finite difference approximation. In fact, the formulation and implementation of three four-point block iterative methods are also presented. Finally, the experimental results show that the Four Point MEGSOR iterative scheme is superior as compared with the existing four point block schemes.
Abstract: In this paper, a new encoding algorithm of spectral envelope based on NLMS in G.729.1 for VoIP is proposed. In the TDAC part of G.729.1, the spectral envelope and MDCT coefficients extracted in the weighted CELP coding error (lower-band) and the higher-band input signal are encoded. In order to reduce allocation bits for spectral envelope coding, a new quantization algorithm based on NLMS is proposed. Also, reduced bits are used to enhance sound quality. The performance of the proposed algorithm is evaluated by sound quality and bit reduction rates in clean and frame loss conditions.
Abstract: This paper presents a novel approach for representing
the spatio-temporal topology of the camera network with overlapping
and non-overlapping fields of view (FOVs). The topology is
determined by tracking moving objects and establishing object
correspondence across multiple cameras. To track people successfully
in multiple camera views, we used the Merge-Split (MS) approach for
object occlusion in a single camera and the grid-based approach for
extracting the accurate object feature. In addition, we considered the
appearance of people and the transition time between entry and exit
zones for tracking objects across blind regions of multiple cameras
with non-overlapping FOVs. The main contribution of this paper is to
estimate transition times between various entry and exit zones, and to
graphically represent the camera topology as an undirected weighted
graph using the transition probabilities.
Abstract: This paper applies fuzzy clustering algorithm in classifying real estate companies in China according to some general financial indexes, such as income per share, share accumulation fund, net profit margins, weighted net assets yield and shareholders' equity. By constructing and normalizing initial partition matrix, getting fuzzy similar matrix with Minkowski metric and gaining the transitive closure, the dynamic fuzzy clustering analysis for real estate companies is shown clearly that different clustered result change gradually with the threshold reducing, and then, it-s shown there is the similar relationship with the prices of those companies in stock market. In this way, it-s great valuable in contrasting the real estate companies- financial condition in order to grasp some good chances of investment, and so on.
Abstract: This paper presents the application of a signal
intensity independent registration criterion for 2D rigid body
registration of medical images using 1D binary projections. The
criterion is defined as the weighted ratio of two projections. The ratio
is computed on a pixel per pixel basis and weighting is performed by
setting the ratios between one and zero pixels to a standard high
value. The mean squared value of the weighted ratio is computed
over the union of the one areas of the two projections and it is
minimized using the Chebyshev polynomial approximation using
n=5 points. The sum of x and y projections is used for translational
adjustment and a 45deg projection for rotational adjustment. 20 T1-
T2 registration experiments were performed and gave mean errors
1.19deg and 1.78 pixels. The method is suitable for contour/surface
matching. Further research is necessary to determine the robustness
of the method with regards to threshold, shape and missing data.
Abstract: In this paper we present an autoregressive model with
neural networks modeling and standard error backpropagation
algorithm training optimization in order to predict the gross domestic
product (GDP) growth rate of four countries. Specifically we propose
a kind of weighted regression, which can be used for econometric
purposes, where the initial inputs are multiplied by the neural
networks final optimum weights from input-hidden layer after the
training process. The forecasts are compared with those of the
ordinary autoregressive model and we conclude that the proposed
regression-s forecasting results outperform significant those of
autoregressive model in the out-of-sample period. The idea behind
this approach is to propose a parametric regression with weighted
variables in order to test for the statistical significance and the
magnitude of the estimated autoregressive coefficients and
simultaneously to estimate the forecasts.
Abstract: A new deployment of the multiple criteria decision
making (MCDM) techniques: the Simple Additive Weighting
(SAW), and the Technique for Order Preference by Similarity to
Ideal Solution (TOPSIS) for portfolio allocation, is demonstrated in
this paper. Rather than exclusive reference to mean and variance as in
the traditional mean-variance method, the criteria used in this
demonstration are the first four moments of the portfolio distribution.
Each asset is evaluated based on its marginal impacts to portfolio
higher moments that are characterized by trapezoidal fuzzy numbers.
Then centroid-based defuzzification is applied to convert fuzzy
numbers to the crisp numbers by which SAW and TOPSIS can be
deployed. Experimental results suggest the similar efficiency of these
MCDM approaches to selecting dominant assets for an optimal
portfolio under higher moments. The proposed approaches allow
investors flexibly adjust their risk preferences regarding higher
moments via different schemes adapting to various (from
conservative to risky) kinds of investors. The other significant
advantage is that, compared to the mean-variance analysis, the
portfolio weights obtained by SAW and TOPSIS are consistently
well-diversified.
Abstract: Multi-user interference (MUI) is the main reason of system deterioration in the Spectral Amplitude Coding Optical Code Division Multiple Access (SAC-OCDMA) system. MUI increases with the number of simultaneous users, resulting into higher probability bit rate and limits the maximum number of simultaneous users. On the other hand, Phase induced intensity noise (PIIN) problem which is originated from spontaneous emission of broad band source from MUI severely limits the system performance should be addressed as well. Since the MUI is caused by the interference of simultaneous users, reducing the MUI value as small as possible is desirable. In this paper, an extensive study for the system performance specified by MUI and PIIN reducing is examined. Vectors Combinatorial (VC) codes families are adopted as a signature sequence for the performance analysis and a comparison with reported codes is performed. The results show that, when the received power increases, the PIIN noise for all the codes increases linearly. The results also show that the effect of PIIN can be minimized by increasing the code weight leads to preserve adequate signal to noise ratio over bit error probability. A comparison study between the proposed code and the existing codes such as Modified frequency hopping (MFH), Modified Quadratic- Congruence (MQC) has been carried out.
Abstract: An adaptive spatial Gaussian mixture model is proposed for clustering based color image segmentation. A new clustering objective function which incorporates the spatial information is introduced in the Bayesian framework. The weighting parameter for controlling the importance of spatial information is made adaptive to the image content to augment the smoothness towards piecewisehomogeneous region and diminish the edge-blurring effect and hence the name adaptive spatial finite mixture model. The proposed approach is compared with the spatially variant finite mixture model for pixel labeling. The experimental results with synthetic and Berkeley dataset demonstrate that the proposed method is effective in improving the segmentation and it can be employed in different practical image content understanding applications.
Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: The aim of the study was to follow changes of powervelocity
relationship in female volleyball players during an annual
training cycle. The study was conducted on eleven female volleyball
players: age 21.6±1.7 years, body height 177.9±4.7 cm, body mass
71.3±6.6 kg and training experience 8.6±3.3 years. Power–velocity
relationship was determined from five maximal 10-second
cycloergometer efforts with external loads equal: 2.5, 5.0, 7.5, 10.0
and 12.5% of body weight (BW) before (I) and after (II) the
preparatory period, after the first (III) and second (IV) competitive
season. The maximal power output increased from 9.30±0.85 W•kg–1
(I) to 9.50±0.96 W•kg–1 (II), 9.77±0.96 W•kg–1 (III) and 9.95±1.13
W•kg–1 (IV, p