Abstract: Dexamethasone (Dex) is a synthetic glucocorticoid
that is used in therapy. However prolonged treatments with high
doses are often required. This causes side effects that interfere with
the activity of several endocrine systems, including the gonadotropic
axis.
The aim of our study is to determine the effect of Dex on testicular
function in prepubertal Wistar rats.
Newborn Wistar rats are submitted to intraperitoneal injection of
Dex (1μg of Dex dissolved in NaCl 0.9% / 5g bw) for 20 days and
then sacrificed at the age of 40days. A control group received NaCl
0.9%. The rat is weighed daily. The plasmatic levels of testosterone,
LH and FSH were measured by radioimmunoassay. A histomorphometric
study was performed on sections of testis.
Treated groups showed a significant decrease in body weight (p
Abstract: The aim of this study was to estimate the frequency of
EBV infection in Hodgkin's lymphoma (HL) and non-Hodgkin's
lymphoma (NHL) occurring in Jordanian patients. A total of 55
patients with lymphoma were examined in this study. Of 55 patients,
30 and 25 were diagnosed as HL and NHL, respectively. The four
HL subtypes were observed with the majority of the cases exhibited
the mixed cellularity (MC) subtype followed by the nodular sclerosis
(NS). The high grade was found to be the commonest subtype of
NHL in our sample, followed by the low grade. The presence of EBV
virus was detected by immunostating for expression of latent
membrane protein-1 (LMP-1). The frequency of LMP-1 expression
occurred more frequent in patients with HL (60.0%) than in patients
with NHL (32.0%). The frequency of LMP-1 expression was also
higher in patients with MC subtype (61.11%) than those patients with
NS (28.57%). No age or gender difference in occurrence of EBV
infection was observed among patient with HL. By contrast, the
prevalence of EBV infection in NHL patients aged below 50 was
lower (16.66%) than in NHL patients aged 50 or above (46.15%). In
addition, EBV infection was more frequent in females with NHL
(38.46%) than in male with NHL (25%). In NHL cases, the
frequency of EBV infection in intermediate grade (60.0%) was high
when compared with frequency of low (25%) or high grades (25%).
In conclusion, analysis of LMP-1 expression indicates an important
role for this viral oncogene in the pathogenesis of EBV-associated
malignant lymphomas. These data also support the previous findings
that people with EBV may develop lymphoma and that efforts to
maintain low lymphoma should be considered for people with EBV
infection.
Abstract: The use of the mechanical simulation (in particular the finite element analysis) requires the management of assumptions in order to analyse a real complex system. In finite element analysis (FEA), two modeling steps require assumptions to be able to carry out the computations and to obtain some results: the building of the physical model and the building of the simulation model. The simplification assumptions made on the analysed system in these two steps can generate two kinds of errors: the physical modeling errors (mathematical model, domain simplifications, materials properties, boundary conditions and loads) and the mesh discretization errors. This paper proposes a mesh adaptive method based on the use of an h-adaptive scheme in combination with an error estimator in order to choose the mesh of the simulation model. This method allows us to choose the mesh of the simulation model in order to control the cost and the quality of the finite element analysis.
Abstract: Advances in technology (e.g. the internet,
telecommunication) and political changes (fewer trade barriers and an
enlarged European Union, ASEAN, NAFTA and other organizations)
have led to develop international competition and expand into new
markets. Companies in Thailand, Asia and around the globe are
increasingly being pressured on price and for faster time to enter the
market. At the same time, new markets are appearing and many
companies are looking for changes and shifts in their domestic
markets. These factors have enabled the rapid growth for companies
and globalizing many different business activities during the product
development process from research and development (R&D) to
production.
This research will show and clarify methods how to develop
global product. Also, it will show how important is a global product
impact into Thai Economy development.
Abstract: In the present study, development of salbutamol
sulphate nanoparticles that adhere to gastric mucus was investigated.
Salbutamol sulphate has low bioavailability due to short transit time in
gastric. It also has a positive surface charge that provides hurdles to be
encapsulated by the positively strong mucoadhesive polymer of
chitosan. To overcome the difficulties, the surface charge of active
ingredient was modified using several nonionic and anionic
stomach-specific polymers. The nanoparticles were prepared using
ionotropic gelation technique. The evaluation involved determination
of particle size, zeta potential, entrapment efficiency, in vitro drug
release and in vitro mucoadhesion test. Results exhibited that the use
of anionic alginate polymer was more satisfactory than that of
nonionic polymer. Characteristics of the particles was nano-size, high
encapsulation efficiency, fulfilled the drug release requirements and
adhesive towards stomach for around 11 hours. This result shows that
the salbutamol sulphate nanoparticles can be utilized for improvement
its delivery.
Abstract: Sleep stage scoring is the process of classifying the
stage of the sleep in which the subject is in. Sleep is classified into
two states based on the constellation of physiological parameters.
The two states are the non-rapid eye movement (NREM) and the
rapid eye movement (REM). The NREM sleep is also classified into
four stages (1-4). These states and the state wakefulness are
distinguished from each other based on the brain activity. In this
work, a classification method for automated sleep stage scoring
based on a single EEG recording using wavelet packet decomposition
was implemented. Thirty two ploysomnographic recording from the
MIT-BIH database were used for training and validation of the
proposed method. A single EEG recording was extracted and
smoothed using Savitzky-Golay filter. Wavelet packets
decomposition up to the fourth level based on 20th order Daubechies
filter was used to extract features from the EEG signal. A features
vector of 54 features was formed. It was reduced to a size of 25 using
the gain ratio method and fed into a classifier of regression trees. The
regression trees were trained using 67% of the records available. The
records for training were selected based on cross validation of the
records. The remaining of the records was used for testing the
classifier. The overall correct rate of the proposed method was found
to be around 75%, which is acceptable compared to the techniques in
the literature.
Abstract: Heavy metal pollution is an environmental concern.
Phytoremediation is a low-cost, environmental-friendly approach to
solve this problem. Mustard has the potential in reducing heavy metal
contents in soils. Among mustard (Brassica juncea (L.) Czern &
Coss) genotypes in Sri Lanka, accessions 7788, 8831 and 5088 give
significantly a high yield. Therefore, present study was conducted to
quantify the phytoextractive potential among these local mustard
accessions and to assess the interaction of heavy metals, Pb, Co, Mn
on phytoextraction. A pot experiment was designed with acid washed
sand (quartz) and a series of heavy metal solutions of 0, 25, 50, 75
and 100 μg/g. Experiment was carried out with factorial
experimental design. Mustard accessions were tolerant to heavy
metals and could be successfully used in removal of Pb, Co and Mn
and they are capable of accumulating significant quantities of heavy
metals in vegetative and reproductive organs. The order of the
accumulative potential of Pb, Co and Mn in mustard accessions is,
root > shoot >seed.
Abstract: The heavy metal contamination of the technogenous
sediments and soils at the investigated dump-field show irregular
planar distribution. Also the heavy metal content in the surface water,
drainage water and in the groundwater was studied both in the dry as
well as during the rainy periods. The cementation process causes
substitution of iron by copper. Natural installation and development
of plant species was observed at the old mine waste dumps, specific
to the local chemical conditions such as low content of essential
nutrients and high content of heavy metals. The individual parts of
the plant tissues (roots, branches/stems, leaves/needles, flowers/
fruits) are contaminated by heavy metals and tissues are damaged
differently, respectively.
Abstract: In power systems, protective relays must filter their
inputs to remove undesirable quantities and retain signal quantities of
interest. This job must be performed accurate and fast. A new
method for filtering the undesirable components such as DC and
harmonic components associated with the fundamental system
signals. The method is s based on a dynamic filtering algorithm. The
filtering algorithm has many advantages over some other classical
methods. It can be used as dynamic on-line filter without the need of
parameters readjusting as in the case of classic filters. The proposed
filter is tested using different signals. Effects of number of samples
and sampling window size are discussed. Results obtained are
presented and discussed to show the algorithm capabilities.
Abstract: An evaluation of the PCBs residues in the surface soils from Bacninh, Vietnam was carried out. Sixty representative soil samples were collected from the centre of Bacninh and three surrounding districts. The analyzed results indicated the wide extent of contamination of total PCBs in Bacninh. In industrial and urban zones, total PCBs concentrations ranged from ranged from
Abstract: The surface water used in this study was collected from the Chao Praya River at the lower part at the Nonthaburi bridge. It was collected and used throughout the experiment. TOC (also known as DOC) in the range between 2.5 to 5.6 mg/l were investigated in this experiment. The use of conventional treatment methods such as FeCl3 and PAC showed that TOC removal was 65% using FeCl3 and 78% using PAC (powder activated carbon). The advanced oxidation process alone showed only 35% removal of TOC. Coupling advanced oxidation with a small amount of PAC (0.05g/L) increased efficiency by upto 55%. The combined BAC with advanced oxidation process and small amount of PAC demonstrated the highest efficiency of up to 95% of TOC removal and lower sludge production compared with other methods.
Abstract: In developing countries located in monsoon areas like
Thailand where rainwater is currently of no value for urban dwellers
due to easily access to piped water supply at each household, studies
in rainwater harvesting for domestic use are of low interest. However
it is needed to undertake research to find out appropriate rainwater
harvesting systems particularly for small urban communities that are
recently developed from a full rural structure to urban context. As a
matter of fact, in such transitional period, relying on only common
water resources is risky. With some specific economic settings, land
use patterns, and historical and cultural context that dominate
perceptions of water users in the study area, the level of service in
this study may certainly be different from megacities or cities located
in industrial zone. The overviews of some available technologies and
background of rainwater harvesting including alternate resource are
included in this paper. Among other sources of water supply, ground
water use as the water resource of Thailand and also in the study area.
Abstract: Process control and energy conservation are the two
primary reasons for using an adjustable speed drive. However,
voltage sags are the most important power quality problems facing
many commercial and industrial customers. The development of
boost converters has raised much excitement and speculation
throughout the electric industry. Now utilities are looking to these
devices for performance improvement and reliability in a variety of
areas. Examples of these include sags, spikes, or transients in supply
voltage as well as unbalanced voltages, poor electrical system
grounding, and harmonics. In this paper, simulations results are
presented for the verification of the proposed boost converter
topology. Boost converter provides ride through capability during
sag and swell. Further, input currents are near sinusoidal. This
eliminates the need of braking resistor also.
Abstract: The paper deals with the effect of ion nitriding and
carbonitriding on fatigue strength of steel parts under the fretting
conditions. Instrumented fatigue tests were carried out on surface
treated flat bars from EA1N and EA4T steels with different strength.
The chosen surfacing decrease importantly an unfavorable fretting
effect. Nitridation suppressed the unfavorable effect of fretting
almost entirely, while the influence of carbonitridation was less
striking. The results were compared with those ones obtained on bars
without surfacing. The causes of favorable influence of surfacing are
discussed.
Abstract: Automated operations based on voice commands will become more and more important in many applications, including robotics, maintenance operations, etc. However, voice command recognition rates drop quite a lot under non-stationary and chaotic noise environments. In this paper, we tried to significantly improve the speech recognition rates under non-stationary noise environments. First, 298 Navy acronyms have been selected for automatic speech recognition. Data sets were collected under 4 types of noisy environments: factory, buccaneer jet, babble noise in a canteen, and destroyer. Within each noisy environment, 4 levels (5 dB, 15 dB, 25 dB, and clean) of Signal-to-Noise Ratio (SNR) were introduced to corrupt the speech. Second, a new algorithm to estimate speech or no speech regions has been developed, implemented, and evaluated. Third, extensive simulations were carried out. It was found that the combination of the new algorithm, the proper selection of language model and a customized training of the speech recognizer based on clean speech yielded very high recognition rates, which are between 80% and 90% for the four different noisy conditions. Fourth, extensive comparative studies have also been carried out.
Abstract: This experiment was conducted to investigate the
effect of dietary supplementation of different levels of black seed
(Nigella sativa L.) on the performance and immune response of broiler chicks. A total 240 day-old broiler chicks were used and
randomly allotted equally into six experimental groups designated as 1, 2, 3, 4, 5 and 6 having black seed at the rate of 0, 2, 4, 6, 8 and
10 g /kg diet respectively. The study was lasted for 42 days. Average body weight, weight gain, relative growth rate, feed
conversion, antibody titer against Newcastle disease, phagocytic activity and phagocytic index, some blood parameters(GOT, GPT,
Glucose, Cholesterol, Triglyceride, Total protein, Albumen, WBCs,
RBCs, Hb and PCV), dressing percentage, weight of different body
organs, abdominal fat weight, were determined. It was found that, N. Sativa significantly improved final body weight, total body gain
and feed conversion ratio of groups 2 and 3 when compared with the control group. Higher levels of N. Sativa did not improve
growth performance of the chicks. Non significant differences were
observed for antibody titer against Newcastle virus, WBCs count,
serum GOT, glucose level, dressing %, relative liver, spleen, heart and head percentages. Lymphoid organs (Bursa and Thymus)
improved significantly with increasing N. Sativa level in all supplemented groups. Serum cholesterol, triglyceride and visible fat
% significantly decreased with Nigella sativa supplementation while
serum GPT level significantly increased with nigella sativa
supplementation.
Abstract: To distinguish small retinal hemorrhages in early
diabetic retinopathy from dust artifacts, we analyzed hue, lightness,
and saturation (HLS) color spaces. The fundus of 5 patients with
diabetic retinopathy was photographed. For the initial experiment, we
placed 4 different colored papers on the ceiling of a darkroom. Using
each color, 10 fragments of house dust particles on a magnifier were
photographed. The colored papers were removed, and 3 different
colored light bulbs were suspended from the ceiling. Ten fragments of
house dust particles on the camera-s object lens were photographed.
We then constructed an experimental device that can photograph
artificial eyes. Five fragments of house dust particles under the ocher
fundus of the artificial eye were photographed. On analyzing HLS
color space of the dust artifact, lightness and saturation were found to
be highly sensitive. However, hue was not highly sensitive.
Abstract: Tourism industry is an important sector in Malaysia economy and this motivates the examination of long-run relationships between tourist arrivals from three selected European countries in Malaysia and four possible determinants; relative prices, exchange rates, transportation cost and relative prices of substitute destination. The study utilizes data from January 1999 to September 2008 and employs standard econometric techniques that include unit root test and cointegration test. The estimated demand model indicates that depreciation of local currency and increases in prices at substitute destination have positive impact on tourist arrivals while increase in transportation cost has negative impact on tourist arrivals. In addition, the model suggests that higher rate of increase in local prices relative to prices at tourist country of origin may not deter tourists from coming to Malaysia
Abstract: Business Process Modeling (BPM) is the first and
most important step in business process management lifecycle. Graph
based formalism and rule based formalism are the two most
predominant formalisms on which process modeling languages are
developed. BPM technology continues to face challenges in coping
with dynamic business environments where requirements and goals
are constantly changing at the execution time. Graph based
formalisms incur problems to react to dynamic changes in Business
Process (BP) at the runtime instances. In this research, an adaptive
and flexible framework based on the integration between Object
Oriented diagramming technique and Petri Net modeling language is
proposed in order to support change management techniques for
BPM and increase the representation capability for Object Oriented
modeling for the dynamic changes in the runtime instances. The
proposed framework is applied in a higher education environment to
achieve flexible, updatable and dynamic BP.
Abstract: This paper focuses on a critical component of the situational awareness (SA), the neural control of depth flight of an autonomous underwater vehicle (AUV). Constant depth flight is a challenging but important task for AUVs to achieve high level of autonomy under adverse conditions. With the SA strategy, we proposed a multirate neural control of an AUV trajectory for a nontrivial mid-small size AUV “r2D4" stochastic model. This control system has been demonstrated and evaluated by simulation of diving maneuvers using software package Simulink. From the simulation results it can be seen that the chosen AUV model is stable in the presence of noises, and also can be concluded that the proposed research technique will be useful for fast SA of similar AUV systems in real-time search-and-rescue operations.