Abstract: Societal security, continuity scenarios and methodological cycling approach explained in this article. Namely societal security organizational challenges ask implementation of international standards BS 25999-2 & global ISO 22300 which is a family of standards for business continuity management system. Efficient global organization system is distinguished of high entity´s complexity, connectivity & interoperability, having not only cooperative relations in a fact. Competing business have numerous participating ´enemies´, which are in apparent or hidden opponent and antagonistic roles with prosperous organization system, resulting to a crisis scene or even to a battle theatre. Organization business continuity scenarios are necessary for such ´a play´ preparedness, planning, management & overmastering in real environments.
Abstract: Lipases are enzymes particularly amenable for
immobilization by entrapment methods, as they can work equally
well in aqueous or non-conventional media and long-time stability of
enzyme activity and enantioselectivity is needed to elaborate more
efficient bioprocesses. The improvement of Pseudomonas
fluorescens (Amano AK) lipase characteristics was investigated by
optimizing the immobilization procedure in hybrid organic-inorganic
matrices using ionic liquids as additives. Ionic liquids containing a
more hydrophobic alkyl group in the cationic moiety are beneficial
for the activity of immobilized lipase. Silanes with alkyl- or aryl
nonhydrolizable groups used as precursors in combination with
tetramethoxysilane could generate composites with higher
enantioselectivity compared to the native enzyme in acylation
reactions of secondary alcohols. The optimal effect on both activity
and enantioselectivity was achieved for the composite made from
octyltrimethoxysilane and tetramethoxysilane at 1:1 molar ratio (60%
increase of total activity following immobilization and enantiomeric
ratio of 30). Ionic liquids also demonstrated valuable properties as
reaction media for the studied reactions, comparable with the usual
organic solvent, hexane.
Abstract: The influence of viscosity on droplet diameter for
water-in-crude oil (w/o) emulsion with two different ratios; 20-80 %
and 50-50 % w/o emulsion was examined in the Brookfield
Rotational Digital Rheometer. The emulsion was prepared with
sorbitan sesquiolate (Span 83) act as emulsifier at varied temperature
and stirring speed in rotation per minute (rpm). Results showed that
the viscosity of w/o emulsion was strongly augmented by increasing
volume of water and decreased the temperature. The changing of
viscosity also altered the droplet size distribution. Changing of
droplet diameter was depends on the viscosity and the behavior of
emulsion either Newtonian or non-Newtonian.
Abstract: At the present, auto part industries have become higher challenge in strategy market. As this consequence, manufacturers need to have better response to customers in terms of quality, cost, and delivery time. Moreover, they need to have a good management in factory to comply with international standard maximum capacity and lower cost. This would lead companies to have to order standard part from aboard and become the major cost of inventory. The development of auto part research by recycling materials experiment is to compare the auto parts from recycle materials to international auto parts (CKD). Factors studied in this research were the recycle material ratios of PU-foam, felt, and fabric. Results of recycling materials were considered in terms of qualities and properties on the parameters such as weight, sound absorption, water absorption, tensile strength, elongation, and heat resistance with the CKD. The results were showed that recycling materials would be used to replace for the CKD.
Abstract: In the past years, the world has witnessed significant work in the field of Manufacturing. Special efforts have been made in the implementation of new technologies, management and control systems, among many others which have all evolved the field. Closely following all this, due to the scope of new projects and the need of turning the existing flexible ideas into more autonomous and intelligent ones, i.e.: moving toward a more intelligent manufacturing, the present paper emerges with the main aim of contributing to the analysis and a few customization issues of a new iCIM 3000 system at the IPSAM. In this process, special emphasis in made on the material flow problem. For this, besides offering a description and analysis of the system and its main parts, also some tips on how to define other possible alternative material flow scenarios and a partial analysis of the combinatorial nature of the problem are offered as well. All this is done with the intentions of relating it with the use of simulation tools, for which these have been briefly addressed with a special focus on the Witness simulation package. For a better comprehension, the previous elements are supported by a few figures and expressions which would help obtaining necessary data. Such data and others will be used in the future, when simulating the scenarios in the search of the best material flow configurations.
Abstract: Lately, significant work in the area of Intelligent
Manufacturing has become public and mainly applied within the
frame of industrial purposes. Special efforts have been made in the
implementation of new technologies, management and control
systems, among many others which have all evolved the field. Aware
of all this and due to the scope of new projects and the need of
turning the existing flexible ideas into more autonomous and
intelligent ones, i.e.: Intelligent Manufacturing, the present paper
emerges with the main aim of contributing to the design and analysis
of the material flow in either systems, cells or work stations under
this new “intelligent" denomination. For this, besides offering a
conceptual basis in some of the key points to be taken into account
and some general principles to consider in the design and analysis of
the material flow, also some tips on how to define other possible
alternative material flow scenarios and a classification of the states a
system, cell or workstation are offered as well. All this is done with
the intentions of relating it with the use of simulation tools, for which
these have been briefly addressed with a special focus on the Witness
simulation package. For a better comprehension, the previous
elements are supported by a detailed layout, other figures and a few
expressions which could help obtaining necessary data. Such data and
others will be used in the future, when simulating the scenarios in the
search of the best material flow configurations.
Abstract: The equilibrium, thermodynamics and kinetics of the
biosorption of Cd (II) and Pb(II) by a Spore Forming Bacillus (MGL
75) were investigated at different experimental conditions. The
Langmuir and Freundlich, and Dubinin-Radushkevich (D-R)
equilibrium adsorption models were applied to describe the
biosorption of the metal ions by MGL 75 biomass. The Langmuir
model fitted the equilibrium data better than the other models.
Maximum adsorption capacities q max for lead (II) and cadmium (II)
were found equal to 158.73mg/g and 91.74 mg/g by Langmuir model.
The values of the mean free energy determined with the D-R equation
showed that adsorption process is a physiosorption process. The
thermodynamic parameters Gibbs free energy (ΔG°), enthalpy (ΔH°),
and entropy (ΔS°) changes were also calculated, and the values
indicated that the biosorption process was exothermic and
spontaneous. Experiment data were also used to study biosorption
kinetics using pseudo-first-order and pseudo-second-order kinetic
models. Kinetic parameters, rate constants, equilibrium sorption
capacities and related correlation coefficients were calculated and
discussed. The results showed that the biosorption processes of both
metal ions followed well pseudo-second-order kinetics.
Abstract: Planning the transition period for the adoption of
alternative fuel-technology powertrains is a challenging task that
requires sophisticated analysis tools. In this study, a system dynamic
approach was applied to analyze the bi-directional interaction
between the development of the refueling station network and vehicle
sales. Besides, the developed model was used to estimate the
transition cost to reach a predefined target (share of alternative fuel
vehicles) in different scenarios. Several scenarios have been analyzed
to investigate the effectiveness and cost of incentives on the initial
price of vehicles, and on the evolution of fuel and refueling stations.
Obtained results show that a combined set of incentives will be more
effective than just a single specific type of incentives.
Abstract: Aptamers are useful tools in microorganism
researches, diagnoses, and treatment. Aptamers are specific target
molecules formed by oligonucleic acid molecules, and are not
decomposed by alcohol. Aptamers used to detect Mycobacterium
tuberculosis (MTB) have been proved to have specific affinity to the
outer membrane proteins of MTB. This article presents a biosensor
chip set with aptamers for early detection of MTB with high specificity
and sensitivity, even in very low concentration. Meanwhile, we have
already made a modified hydrophobic facial mask module with
internal rendering hydrophobic for effectively collecting M.
tuberculosis.
Abstract: Pakistani doctors (MBBS) are emigrating towards developed countries for professional adjustments. This study aims to highlight causes and consequences of doctors- brain drain from Pakistan. Primary data was collected from Mayo Hospital, Lahore by interviewing doctors (n=100) through systematic random sampling technique. It found that various socio-economic and political conditions are working as push and pull factors for brain drain of doctors in Pakistan. Majority of doctors (83%) declared poor remunerations and professional infrastructure of health department as push factor of doctors- brain drain. 81% claimed that continuous instability in political situation and threats of terrorism are responsible for emigration of doctors. 84% respondents considered fewer opportunities of further studies responsible for their emigration. Brain drain of doctors is affecting health sector-s policies / programs, standard doctor-patient ratios and quality of health services badly.
Abstract: In this study thermodynamic performance analysis of a
combined organic Rankine cycle and ejector refrigeration cycle is
carried out for use of low-grade heat source in the form of sensible
energy. Special attention is paid to the effects of system parameters
including the turbine inlet temperature and turbine inlet pressure on the
characteristics of the system such as ratios of mass flow rate, net work
production, and refrigeration capacity as well as the coefficient of
performance and exergy efficiency of the system. Results show that
for a given source the coefficient of performance increases with
increasing of the turbine inlet pressure. However, the exergy
efficiency has an optimal condition with respect to the turbine inlet
pressure.
Abstract: Evolutionary Algorithms are population-based,
stochastic search techniques, widely used as efficient global
optimizers. However, many real life optimization problems often
require finding optimal solution to complex high dimensional,
multimodal problems involving computationally very expensive
fitness function evaluations. Use of evolutionary algorithms in such
problem domains is thus practically prohibitive. An attractive
alternative is to build meta models or use an approximation of the
actual fitness functions to be evaluated. These meta models are order
of magnitude cheaper to evaluate compared to the actual function
evaluation. Many regression and interpolation tools are available to
build such meta models. This paper briefly discusses the
architectures and use of such meta-modeling tools in an evolutionary
optimization context. We further present two evolutionary algorithm
frameworks which involve use of meta models for fitness function
evaluation. The first framework, namely the Dynamic Approximate
Fitness based Hybrid EA (DAFHEA) model [14] reduces
computation time by controlled use of meta-models (in this case
approximate model generated by Support Vector Machine
regression) to partially replace the actual function evaluation by
approximate function evaluation. However, the underlying
assumption in DAFHEA is that the training samples for the metamodel
are generated from a single uniform model. This does not take
into account uncertain scenarios involving noisy fitness functions.
The second model, DAFHEA-II, an enhanced version of the original
DAFHEA framework, incorporates a multiple-model based learning
approach for the support vector machine approximator to handle
noisy functions [15]. Empirical results obtained by evaluating the
frameworks using several benchmark functions demonstrate their
efficiency
Abstract: The purpose of this study was to evaluate and
compare new indices based on the discrete wavelet transform
with another spectral parameters proposed in the literature as
mean average voltage, median frequency and ratios between
spectral moments applied to estimate acute exercise-induced
changes in power output, i.e., to assess peripheral muscle
fatigue during a dynamic fatiguing protocol. 15 trained
subjects performed 5 sets consisting of 10 leg press, with 2
minutes rest between sets. Surface electromyography was
recorded from vastus medialis (VM) muscle. Several surface
electromyographic parameters were compared to detect
peripheral muscle fatigue. These were: mean average voltage
(MAV), median spectral frequency (Fmed), Dimitrov spectral
index of muscle fatigue (FInsm5), as well as other five
parameters obtained from the discrete wavelet transform
(DWT) as ratios between different scales. The new wavelet
indices achieved the best results in Pearson correlation
coefficients with power output changes during acute dynamic
contractions. Their regressions were significantly different
from MAV and Fmed. On the other hand, they showed the
highest robustness in presence of additive white gaussian
noise for different signal to noise ratios (SNRs). Therefore,
peripheral impairments assessed by sEMG wavelet indices
may be a relevant factor involved in the loss of power output
after dynamic high-loading fatiguing task.
Abstract: This paper presents a generalized formulation for the
problem of buckling optimization of anisotropic, radially graded,
thin-walled, long cylinders subject to external hydrostatic pressure.
The main structure to be analyzed is built of multi-angle fibrous
laminated composite lay-ups having different volume fractions of the
constituent materials within the individual plies. This yield to a
piecewise grading of the material in the radial direction; that is the
physical and mechanical properties of the composite material are
allowed to vary radially. The objective function is measured by
maximizing the critical buckling pressure while preserving the total
structural mass at a constant value equals to that of a baseline
reference design. In the selection of the significant optimization
variables, the fiber volume fractions adjoin the standard design
variables including fiber orientation angles and ply thicknesses. The
mathematical formulation employs the classical lamination theory,
where an analytical solution that accounts for the effective axial and
flexural stiffness separately as well as the inclusion of the coupling
stiffness terms is presented. The proposed model deals with
dimensionless quantities in order to be valid for thin shells having
arbitrary thickness-to-radius ratios. The critical buckling pressure
level curves augmented with the mass equality constraint are given
for several types of cylinders showing the functional dependence of
the constrained objective function on the selected design variables. It
was shown that material grading can have significant contribution to
the whole optimization process in achieving the required structural
designs with enhanced stability limits.
Abstract: This paper investigates and compares performance of
various conventional and fuzzy logic based controllers at generator
locations for oscillation damping. Performance of combination of
conventional and fuzzy logic based controllers also studied by
comparing overshoot on the active power deviation response for a
small disturbance and damping ratio of the critical mode. Fuzzy logic
based controllers can not be modeled in the state space form to get
the eigenvalues and corresponding damping ratios of various modes
of generators and controllers. Hence, a new method based on tracing
envelop of time domain waveform is also presented and used in the
paper for comparing performance of controllers. The paper also
shows that if the fuzzy based controllers designed separately
combining them could not lead to a better performance.
Abstract: The paper presents a compressor anti-surge control
system, that results in maximizing compressor throughput with
pressure standard deviation reduction, increased safety margin
between design point and surge limit line and avoiding possible
machine surge. Alternative control strategies are presented.
Abstract: Application of nanoparticles as additives in membrane
synthesis for improving the resistance of membranes against fouling
has triggered recent interest in new membrane types. However, most
nanoparticle-enhanced membranes suffer from the tradeoff between
permeability and selectivity. In this study, nano-WS2 was explored as
the additive in membrane synthesis by non-solvent induced phase
separation. Blended PES-WS2 flat-sheet membranes with the
incorporation of ultra-low concentrations of nanoparticles (from 0.025
to 0.25%, WS2/PES ratio) were manufactured and investigated in
terms of permeability, fouling resistance and solute rejection.
Remarkably, a significant enhancement in the permeability was
observed as a result of the incorporation of ultra-low fractions of
nano-WS2 to the membrane structure. Optimal permeability values
were obtained for modified membranes with 0.10%
nanoparticle/polymer concentration ratios. Furthermore, fouling
resistance and solute rejection were significantly improved by the
incorporation of nanoparticles into the membrane matrix. Specifically,
fouling resistance of modified membrane can increase by around 50%.
Abstract: This work evaluated the effect of temperature on headspace solid-phase microextraction of volatile and furanic compounds in coated fish sticks. The major goal was the analysis of the samples as consumed, to reproduce volatile compounds people feel when consuming those products. Extraction at 37 ºC (the human body temperature) throughout the HS-SPME analysis of volatile and furanic compounds in coated fish was compared with higher extraction temperatures, which are frequently used for this kind of determinations. The profile of volatile compounds found in deepfried (F) and non-fried (NF) coated fish at 37 and 50 ºC was different from that obtained at 80 ºC. Concerning furan and its derivatives, an extra formation of these compounds was observed at higher extraction temperatures. The analysis of volatile and furanic compounds in fish coated sticks simulating the cooking and eating conditions can be reliably carried out setting the headspace absorption temperature at 37 ºC.
Abstract: Availability of high dimensional biological datasets such as from gene expression, proteomic, and metabolic experiments can be leveraged for the diagnosis and prognosis of diseases. Many classification methods in this area have been studied to predict disease states and separate between predefined classes such as patients with a special disease versus healthy controls. However, most of the existing research only focuses on a specific dataset. There is a lack of generic comparison between classifiers, which might provide a guideline for biologists or bioinformaticians to select the proper algorithm for new datasets. In this study, we compare the performance of popular classifiers, which are Support Vector Machine (SVM), Logistic Regression, k-Nearest Neighbor (k-NN), Naive Bayes, Decision Tree, and Random Forest based on mock datasets. We mimic common biological scenarios simulating various proportions of real discriminating biomarkers and different effect sizes thereof. The result shows that SVM performs quite stable and reaches a higher AUC compared to other methods. This may be explained due to the ability of SVM to minimize the probability of error. Moreover, Decision Tree with its good applicability for diagnosis and prognosis shows good performance in our experimental setup. Logistic Regression and Random Forest, however, strongly depend on the ratio of discriminators and perform better when having a higher number of discriminators.