Abstract: Retinoblastoma is a rare type of childhood genetic cancer that affects children worldwide. The diagnosis is often missed due to lack of education and difficulty in presentation of the tumor. Frequently, the tumor on the retina is noticed by photography when the red-eye flash, commonly seen in normal eyes, is not produced. Instead, a yellow or white colored patch is seen or the child has a noticeable strabismus. Early detection can be life-saving though often results in removal of the affected eye. Remaining functioning in the healthy eye when the child is young has resulted in super-vision and high or above-average intelligence. Technological advancement of cameras has helped in early detection. Brain imaging has also made possible early detection of neurological diseases and, together with the monitoring of cortisol levels and yawning frequency, promises to be the next new early diagnostic tool for the detection of neurological diseases where cortisol insufficiency is particularly salient, such as multiple sclerosis and Cushing’s disease.
Abstract: Main goal of preventive healthcare problems are at
decreasing the likelihood and severity of potentially life-threatening
illnesses by protection and early detection. The levels of
establishment and staffing costs along with summation of the travel
and waiting time that clients spent are considered as objectives
functions of the proposed nonlinear integer programming model. In
this paper, we have proposed a bi-objective mathematical model for
designing a network of preventive healthcare facilities so as to
minimize aforementioned objectives, simultaneously. Moreover, each
facility acts as M/M/1 queuing system. The number of facilities to be
established, the location of each facility, and the level of technology
for each facility to be chosen are provided as the main determinants
of a healthcare facility network. Finally, to demonstrate performance
of the proposed model, four multi-objective decision making
techniques are presented to solve the model.
Abstract: Aptamers are useful tools in microorganism
researches, diagnoses, and treatment. Aptamers are specific target
molecules formed by oligonucleic acid molecules, and are not
decomposed by alcohol. Aptamers used to detect Mycobacterium
tuberculosis (MTB) have been proved to have specific affinity to the
outer membrane proteins of MTB. This article presents a biosensor
chip set with aptamers for early detection of MTB with high specificity
and sensitivity, even in very low concentration. Meanwhile, we have
already made a modified hydrophobic facial mask module with
internal rendering hydrophobic for effectively collecting M.
tuberculosis.