Abstract: The mechanical properties of granular solids are
dependent on the flow of stresses from one particle to another
through inter-particle contact. Although some experimental methods
have been used to study the inter-particle contacts in the past,
preliminary work with these techniques indicated that they do not
have the necessary resolution to distinguish between those contacts
that transmit the load and those that do not, especially for systems
with a wide distribution of particle sizes. In this research, computer
simulations are used to study the nature and distribution of contacts
in a compact with wide particle size distribution, representative of
aggregate size distribution used in asphalt pavement construction.
The packing fraction, the mean number of contacts and the
distribution of contacts were studied for different scenarios. A
methodology to distinguish and compute the fraction of load-bearing
particles and the fraction of space-filling particles (particles that do
not transmit any force) is needed for further investigation.
Abstract: A numerical study is presented on buckling and post
buckling behaviour of laminated carbon fiber reinforced plastic
(CFRP) thin-walled cylindrical shells under axial compression using
asymmetric meshing technique (AMT). Asymmetric meshing
technique is a perturbation technique to introduce disturbance without
changing geometry, boundary conditions or loading conditions.
Asymmetric meshing affects predicted buckling load, buckling mode
shape and post-buckling behaviour. Linear (eigenvalue) and nonlinear
(Riks) analyses have been performed to study the effect of
asymmetric meshing in the form of a patch on buckling behaviour.
The reduction in the buckling load using Asymmetric meshing
technique was observed to be about 15%. An isolated dimple formed
near the bifurcation point and the size of which increased to reach a
stable state in the post-buckling region. The load-displacement curve
behaviour applying asymmetric meshing is quite similar to the curve
obtained using initial geometric imperfection in the shell model.
Abstract: This study was conducted published to investigate
there liability of the equation pressure-impulse (PI) reinforced
concrete column inprevious studies. Equation involves three different
levels of damage criteria known as D =0. 2, D =0. 5 and D =0. 8.The
damage criteria known as a minor when 0-0.2, 0.2-0.5is known as
moderate damage, high damage known as 0.5-0.8, and 0.8-1 of the
structure is considered a failure. In this study, two types of reliability
analyzes conducted. First, using pressure-impulse equation with
different parameters. The parameters involved are the concrete
strength, depth, width, and height column, the ratio of longitudinal
reinforcement and transverse reinforcement ratio. In the first analysis
of the reliability of this new equation is derived to improve the
previous equations. The second reliability analysis involves three
types of columns used to derive the PI curve diagram using the
derived equation to compare with the equation derived from other
researchers and graph minimum standoff versus weapon yield
Federal Emergency Management Agency (FEMA). The results
showed that the derived equation is more accurate with FEMA
standards than previous researchers.
Abstract: Type 2 diabetes mellitus (T2DM) is a complex
metabolic disorder that characterized by the presence of high glucose
in blood that cause from insulin resistance and insufficiency due to
deterioration β-cell Langerhans functions. T2DM is commonly
caused by the combination of inherited genetic variations as well as
our own lifestyle. Metallothionein (MT) is a known cysteine-rich
protein responsible in helping zinc homeostasis which is important in
insulin signaling and secretion as well as protection our body from
reactive oxygen species (ROS). MT scavenged ROS and free
radicals in our body happen to be one of the reasons of T2DM and its
complications. The objective of this study was to investigate the
association of MT1A and MT2A polymorphisms between T2DM and
control subjects among Malay populations. This study involved 150
T2DM and 120 Healthy individuals of Malay ethnic with mixed
genders. The genomic DNA was extracted from buccal cells and
amplified for MT1A and MT2A loci; the 347bp and 238bp banding
patterns were respectively produced by mean of the Polymerase
Chain Reaction (PCR). The PCR products were digested with Mlucl
and Tsp451 restriction enzymes respectively and producing
fragments lengths of (158/189/347bp) and (103/135/238bp)
respectively. The ANOVA test was conducted and it shown that there
was a significant difference between diabetic and control subjects for
age, BMI, WHR, SBP, FPG, HBA1C, LDL, TG, TC and family
history with (P0.05). The genotype
frequency for AA, AG and GG of MT1A polymorphisms was 72.7%,
22.7% and 4.7% in cases and 15%, 55% and 30% in control
respectively. As for MT2A, genotype frequency of GG, GC and CC
was 42.7%, 27.3% and 30% in case and 5%, 40% and 55% for
control respectively. Both polymorphisms show significant difference
between two investigated groups with (P=0.000). The Post hoc test
was conducted and shows a significant difference between the
genotypes within each polymorphism (P=0. 000). The MT1A and
MT2A polymorphisms were believed to be the reliable molecular
markers to distinguish the T2DM subjects from healthy individuals in
Malay populations.
Abstract: It has been established that microRNAs (miRNAs) play
an important role in gene expression by post-transcriptional regulation
of messengerRNAs (mRNAs). However, the precise relationships
between microRNAs and their target genes in sense of numbers,
types and biological relevance remain largely unclear. Dissecting the
miRNA-target relationships will render more insights for miRNA
targets identification and validation therefore promote the understanding
of miRNA function. In miRBase, miRanda is the key
algorithm used for target prediction for Zebrafish. This algorithm
is high-throughput but brings lots of false positives (noise). Since
validation of a large scale of targets through laboratory experiments
is very time consuming, several computational methods for miRNA
targets validation should be developed. In this paper, we present an
integrative method to investigate several aspects of the relationships
between miRNAs and their targets with the final purpose of extracting
high confident targets from miRanda predicted targets pool. This is
achieved by using the techniques ranging from statistical tests to
clustering and association rules. Our research focuses on Zebrafish.
It was found that validated targets do not necessarily associate with
the highest sequence matching. Besides, for some miRNA families,
the frequency of their predicted targets is significantly higher in the
genomic region nearby their own physical location. Finally, in a case
study of dre-miR-10 and dre-miR-196, it was found that the predicted
target genes hoxd13a, hoxd11a, hoxd10a and hoxc4a of dre-miR-
10 while hoxa9a, hoxc8a and hoxa13a of dre-miR-196 have similar
characteristics as validated target genes and therefore represent high
confidence target candidates.
Abstract: The study of the variability of the postural strategies
in low back pain patients, as a criterion in evaluation of the
adaptability of this system to the environmental demands is the
purpose of this study. A cross-sectional case-control study was
performed on 21 recurrent non-specific low back pain patients and 21
healthy volunteers. The electromyography activity of Deltoid,
External Oblique (EO), Transverse Abdominis/Internal Oblique
(TrA/IO) and Erector Spine (ES) muscles of each person was
recorded in 75 rapid arm flexion with maximum acceleration.
Standard deviation of trunk muscles onset relative to deltoid muscle
onset were statistically analyzed by MANOVA . The results show
that chronic low back pain patients exhibit less variability in their
anticipatory postural adjustments (APAs) in comparison with the
control group. There is a decrease in variability of postural control
system of recurrent non-specific low back pain patients that can
result in the persistence of pain and chronicity by decreasing the
adaptability to environmental demands.
Abstract: The use of Electronic Commerce (EC)
technologies enables Small Medium Enterprises (SMEs) to improve their efficiency and competitive position. Much of the literature proposes an extensive set of benefits for
organizations that choose to adopt and implement ECommerce
systems. Factors of Business –to-business (B2B)
E-Commerce adoption and implementation have been
extensively investigated. Despite enormous attention given to encourage Small Medium Enterprises (SMEs) to adopt and
implement E-Commerce, little research has been carried out in identifying the factors of Business-to-Consumer ECommerce adoption and implementation for SMEs. To conduct the study, Tornatsky and Fleischer model was adopted
and tested in four SMEs located in Christchurch, New
Zealand. This paper explores the factors that impact the
decision and method of adoption and implementation of ECommerce
systems in automobile industry. Automobile
industry was chosen because the product they deal with i.e.
cars are not a common commodity to be sold online, despite this fact the eCommerce penetration in automobile industry is
high. The factors that promote adoption and implementation of
E-Commerce technologies are discussed, together with the
barriers. This study will help SME owners to effectively
handle the adoption and implementation process and will also
improve the chance of successful E-Commerce
implementation. The implications of the findings for
managers, consultants, and government organizations engaged in promoting E-Commerce adoption and implementation in
small businesses and future research are discussed.
Abstract: An experiment was conducted with 80 unsexed
broilers of the Arbor Acress strain to determine the capability of a
carrot and fruit juice wastes mixture (carrot, apple, manggo, avocado,
orange, melon and Dutch egg plant) in the same proportion for
replacing corn in broiler diet. This study involved a completely
randomized design (CRD) with 5 treatments (0, 5, 10, 15, and 20% of
juice wastes mixture in diets) and 4 replicates per treatment. Diets
were isonitrogenous (22% crude protein) and isocaloric (3000 kcal/kg
diet). Measured variables were feed consumption, average daily
gain, feed conversion, as well as percentages of abdominal fat pad,
carcass, digestive organs (liver, pancreas and gizzard), and heart.
Data were analyzed by analysis of variance for CRD. Increasing
juice wastes mixture levels in diets increased feed consumption
(P
Abstract: The purpose of this paper is to introduce an interactive online case-study library website developed in a national project. The design goal of the website is to provide interactive, enhanced, case-based and online educational resource for educators through the purpose and within the scope of a national project. The ADDIE instructional design model was used in the development of the website for interactive case-based library. This library is developed on a web-based platform, which is important in terms of manageability, accessibility, and updateability of data. Users are able to sort the displayed case-studies by their titles, dates, ratings, view counts, etc. The usability test is used and the expert opinion is taken for the evaluation of the website. This website is a tool to integrate technology into education. It is believed that this website will be beneficial for pre-service and in-service teachers in terms of their professional developments.
Abstract: Numerous concrete structures projects are currently running in Libya as part of a US$50 billion government funding. The
quality of concrete used in 20 different construction projects were assessed based mainly on the concrete compressive strength achieved. The projects are scattered all over the country and are at
various levels of completeness. For most of these projects, the
concrete compressive strength was obtained from test results of a
150mm standard cube mold. Statistical analysis of collected concrete
compressive strengths reveals that the data in general followed a
normal distribution pattern. The study covers comparison and assessment of concrete quality aspects such as: quality control, strength range, data standard deviation, data scatter, and ratio of minimum strength to design strength. Site quality control for these projects ranged from very good to poor according to ACI214 criteria [1]. The ranges (Rg) of the strength (max. strength – min. strength) divided by average strength are from (34% to 160%). Data scatter is
measured as the range (Rg) divided by standard deviation () and is
found to be (1.82 to 11.04), indicating that the range is ±3σ.
International construction companies working in Libya follow
different assessment criteria for concrete compressive strength in lieu
of national unified procedure. The study reveals that assessments of
concrete quality conducted by these construction companies usually
meet their adopted (internal) standards, but sometimes fail to meet
internationally known standard requirements. The assessment of
concrete presented in this paper is based on ACI, British standards
and proposed Libyan concrete strength assessment criteria.
Abstract: Mycophenolic acid “MPA" is a secondary metabolite
of Penicillium bervicompactum with antibiotic and
immunosuppressive properties. In this study, fermentation process
was established for production of mycophenolic acid by Penicillium
bervicompactum MUCL 19011 in shake flask. The maximum MPA
production, product yield and productivity were 1.379 g/L, 18.6 mg/g
glucose and 4.9 mg/L.h respectively. Glucose consumption, biomass
and MPA production profiles were investigated during fermentation
time. It was found that MPA production starts approximately after
180 hours and reaches to a maximum at 280 h. In the next step, the
effects of methionine and acetate concentrations on MPA production
were evaluated. Maximum MPA production, product yield and
productivity (1.763 g/L, 23.8 mg/g glucose and 6.30 mg/L. h
respectively) were obtained with using 2.5 g/L methionine in culture
medium. Further addition of methionine had not more positive effect
on MPA production. Finally, results showed that the addition of
acetate to the culture medium had not any observable effect on MPA
production.
Abstract: Perhaps no single issue has been cited as either the root
cause and / or the greatest challenge to the restructured power system then the lack of adequate reliable transmission. Probabilistic transmission planning has become increasingly necessary and important in recent
years. The transmission planning analysis carried out by the authors,
spans a 10-year horizon, taking into consideration a value of 2 % load
increase / year at each consumer. Taking into consideration this increased
load, a probabilistic power flow was carried out, all the system components
being regarded from probabilistic point of view. Several contingencies
have been generated, for assessing the security of the power system. The results have been analyzed and several important conclusions were pointed. The objective is to achieve a network that works without limit violations for all (or most of) scenario realizations. The case study is represented by the IEEE 14 buses test power system.
Abstract: Stability of functionally graded beams with piezoelectric layers subjected to axial compressive load that is simply supported at both ends is studied in this paper. The displacement field of beam is assumed based on first order shear deformation beam theory. Applying the Hamilton's principle, the governing equation is established. The influences of applied voltage, dimensionless geometrical parameter, functionally graded index and piezoelectric thickness on the critical buckling load of beam are presented. To investigate the accuracy of the present analysis, a compression study is carried out with a known data.
Abstract: Drought is a phenomenon caused by
environmental and climatic changes. This phenomenon is
affected by shortage of rainfall and temperature. Dust is one
of important environmental problems caused by climate
change and drought. With recent multi-year drought, many
environmental crises caused by dust in Iran and Middle East.
Dust in the vast areas of the provinces occurs with high
frequency. By dust affecting many problems created in terms
of health, social and economic. In this study, we tried to study
the most important factors causing dust. In this way we have
used the satellite images and meteorological data. Finally,
strategies to deal with the dust will be mentioned.
Abstract: Information theory and Statistics play an important role in Biological Sciences when we use information measures for the study of diversity and equitability. In this communication, we develop the link among the three disciplines and prove that sampling distributions can be used to develop new information measures. Our study will be an interdisciplinary and will find its applications in Biological systems.
Abstract: We study a long-range percolation model in the hierarchical
lattice ΩN of order N where probability of connection between
two nodes separated by distance k is of the form min{αβ−k, 1},
α ≥ 0 and β > 0. The parameter α is the percolation parameter,
while β describes the long-range nature of the model. The ΩN is
an example of so called ultrametric space, which has remarkable
qualitative difference between Euclidean-type lattices. In this paper,
we characterize the sizes of large clusters for this model along the
line of some prior work. The proof involves a stationary embedding
of ΩN into Z. The phase diagram of this long-range percolation is
well understood.
Abstract: This study suggests a model of a new set of evaluation criteria that will be used to measure the efficiency of real-world E-commerce websites. Evaluation criteria include design, usability and performance for websites, the Data Envelopment Analysis (DEA) technique has been used to measure the websites efficiency. An efficient Web site is defined as a site that generates the most outputs, using the smallest amount of inputs. Inputs refer to measurements representing the amount of effort required to build, maintain and perform the site. Output is amount of traffic the site generates. These outputs are measured as the average number of daily hits and the average number of daily unique visitors.
Abstract: This paper is concerned with the study of mineralogy
and engineering characteristics of soil materials derived from the
eastern part of Nile Delta. The clay minerals of the studied soil by
using X- ray diffraction are mainly illite (average 72.6 %) and
kaolinite (average 2.6 %), expandable portion in illite-smectite mixed
layer (average 7 %). Smectite is more abundant in fluviatile clays,
whereas kaolinite is more abundant in lagoonal clays. On the other
hand, illite and illite-smectite are more abundant in marine clays. The
geotechnical results show that the soil under study consists mainly of
about 0.3 % gravel, 5 % sand, 51.5 % silt and 42.2 % clay in average.
The average shrinkage limit attains 11 % whereas the average value
of the plasticity index is 23.4 %. The free swelling ranges from 40 %
to 75 % and has a value of 55 % giving an indication about the
inadequacy of such soil under foundations.
From a construction point of view, the soil under investigation
poses many problems even under light foundations due to the
swelling and shrinkage. Such swelling and shrinkage is due to the
high content of soil materials in the expandable clay minerals of illite
and smectite. Based on the results of the present and earlier studies,
trial application of soil stabilisation is recommended.
Abstract: The mountain road slope failures triggered by
earthquake activities and torrential rain namely to create the disaster.
Province Road No. 24 is a main route to the Wutai Township. The area
of the study is located at the mileages between 46K and 47K along the
road. However, the road has been suffered frequent damages as a result
of landslide and slope failures during typhoon seasons. An
understanding of the sliding behaviors in the area appears to be
necessary. Slope failures triggered by earthquake activities and heavy
rainfalls occur frequently. The study is to understand the mechanism
of slope failures and to look for the way to deal with the situation. In
order to achieve these objectives, this paper is based on theoretical and
structural geology data interpretation program to assess the potential
slope sliding behavior. The study showed an intimate relationship
between the landslide behavior of the slopes and the stratum materials,
based on structural geology analysis method to analysis slope stability
and finds the slope safety coefficient to predict the sites of destroyed
layer. According to the case study and parameter analyses results, the
slope mainly slips direction compared to the site located in the
southeast area. Find rainfall to result in the rise of groundwater level is
main reason of the landslide mechanism. Future need to set up
effective horizontal drain at corrective location, that can effective
restrain mountain road slope failures and increase stability of slope.
Abstract: In this paper, gate leakage current has been mitigated
by the use of novel nanoscale MOSFET with Source/Drain-to-Gate
Non-overlapped and high-k spacer structure for the first time. A
compact analytical model has been developed to study the gate
leakage behaviour of proposed MOSFET structure. The result
obtained has found good agreement with the Sentaurus Simulation.
Fringing gate electric field through the dielectric spacer induces
inversion layer in the non-overlap region to act as extended S/D
region. It is found that optimal Source/Drain-to-Gate Non-overlapped
and high-k spacer structure has reduced the gate leakage current to
great extent as compared to those of an overlapped structure. Further,
the proposed structure had improved off current, subthreshold slope
and DIBL characteristic. It is concluded that this structure solves the
problem of high leakage current without introducing the extra series
resistance.