Abstract: Nowadays, the rapid development of CAD systems’
programming environments results in the creation of multiple
downstream applications, which are developed and becoming
increasingly available. CAD based manufacturing simulations is
gradually following the same trend. Drilling is the most popular holemaking
process used in a variety of industries. A specially built piece
of software that deals with the drilling kinematics is presented. The
cutting forces are calculated based on the tool geometry, the cutting
conditions and the tool/work-piece materials. The results are verified
by experimental work. Finally, the response surface methodology
(RSM) is applied and mathematical models of the total thrust force
and the thrust force developed because of the main cutting edges are
proposed.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: To ensure targeting of apoferritin nanocarrier with
encapsulated doxorubicin drug, we used a peptide linker based on a
protein G with N-terminus affinity towards Fc region of antibodies.
To connect the peptide to the surface of apoferritin, the C-terminus of
peptide was made of cysteine with affinity to gold. The surface of
apoferritin with encapsulated doxorubicin (APODOX) was coated
either with gold nanoparticles (APODOX-Nano) or gold(III) chloride
hydrate reduced with sodium borohydride (APODOX-HAu). The
reduction with sodium borohydride caused a loss of doxorubicin
fluorescent properties and probably accompanied with the loss of its
biological activity. Fluorescent properties of APODOX-Nano were
similar to the unmodified APODOX; therefore it was more suited for
the intended use. To evaluate the specificity of apoferritin modified
with antibodies, ELISA-like method was used with the surface of
microtitration plate wells coated by the antigen (goat anti-human IgG
antibodies). To these wells, the nanocarrier was applied. APODOX
without the modification showed 5× lower affinity to the antigen than
APODOX-Nano modified gold and targeting antibodies (human IgG
antibodies).
Abstract: In the past decade, the use of digital image correlation
(DIC) techniques has increased significantly in the area of
experimental mechanics, especially for materials behavior
characterization. This non-contact tool enables full field displacement
and strain measurements over a complete region of interest. The DIC
algorithm requires a random contrast pattern on the surface of the
specimen in order to perform properly. To create this pattern, the
specimen is usually first coated using a white matt paint. Next, a
black random speckle pattern is applied using any suitable method. If
the applied paint coating is too thick, its top surface may not be able
to exactly follow the deformation of the specimen, and consequently,
the strain measurement might be underestimated. In the present
article, a study of the influence of the paint thickness on the strain
underestimation is performed for different strain levels. The results
are then compared to typical paint coating thicknesses applied by
experienced DIC users. A slight strain underestimation was observed
for paint coatings thicker than about 30μm. On the other hand, this
value was found to be uncommonly high compared to coating
thicknesses applied by DIC users.
Abstract: To mitigate the urban heat island effect has become a
global issue when we are faced with the challenge of climate change.
Through literature review, plant photosynthesis can reduce the carbon
dioxide and mitigate the urban heat island effect to a degree. Because
there are not enough open space and parks, green roof has become an
important policy in Taiwan.
We selected elementary school buildings in northern New Taipei
City as research subjects since elementary schools are asked with
priority to build green roof and important educational place to promote
green roof concept. Testo175-H1 recording device was used to record
the temperature and humidity differences between roof surface and
interior space below roof with and without green roof in the long-term.
We also use questionnaires to investigate the awareness of comfort
level of green roof and sensation of teachers and students of the
elementary schools.
The results indicated that the temperature of roof without greening
was higher than that with greening by about 2°C. But sometimes
during noontime, the temperature of green roof was higher than that of
non-green roof probably because of the character of the accumulation
and dissipation of heat of greening. The temperature of the interior
space below green roof was normally lower than that without green
roof by about 1°C, showing that green roof could lower the
temperature. The humidity of the green roof was higher than the one
without greening also indicated that green roof retained water better.
Teachers liked to combine green roof concept in the curriculum,
and students wished all classes can take turns to maintain the green
roof. Teachers and students whose school had integrated green roof
concept in the curriculum were more willing to participate in the
maintenance work of green roof. Teachers and students who may have
access to and touch the green roof can be more aware of the green roof
benefit. We suggest architects to increase the accessibility and
visibility of green roof, such as use it as a part of the activity space.
This idea can be a reference to the green roof curriculum design.
Abstract: In the present research work we present the optical
emission studies of the Indium (In) – Tin (Sn) plasma produced by
the first (1064 nm) harmonic of an Nd: YAG nanosecond pulsed
laser. The experimentally observed line profiles of neutral Indium (In
I) and Tin (SnI) are used to extract the electron temperature (Te)
using the Boltzmann plot method. Whereas, the electron number
density (Ne) has been determined from the Stark broadening line
profile method. The Te is calculated by varying the distance from the
target surface along the line of propagation of plasma plume and also
by varying the laser irradiance. Beside we have studied the variation
of Ne as a function of laser irradiance as well as its variation with
distance from the target surface.
Abstract: Development of new generation bio-tribological,
multilayer coatings opens an avenue for fabrication of future hightech
functional surfaces. In the presented work, nano-composite,
Cr/CrN+[Cr/ a-C:H implanted by metallic nanocrystals] multilayer
coatings have been developed for surface protection of medical tools.
Thin films were fabricated by a hybrid Pulsed Laser Deposition
technique. Complex microstructure analysis of nanomultilayer
coatings, subjected to mechanical and biological tests, were
performed by means of transmission electron microscopy (TEM).
Microstructure characterization revealed the layered arrangement of
Cr23C6 nanoparticles in multilayer structure. Influence of deposition
conditions on bio-tribological properties of the coatings was studied.
The bio-tests were used as a screening tool for the analyzed
nanomultilayer coatings before they could be deposited on medical
tools. Bio-medical tests were done using fibroblasts. The mechanical
properties of the coatings were investigated by means of a ball-ondisc
mechanical test. The micro hardness was done using Berkovich
indenter. The scratch adhesion test was done using Rockwell
indenter. From the bio-tribological point of view, the optimal
properties had the C106_1 material.
Abstract: WO3/SiO2 catalysts were modified by an ion exchange
method with sodium hydroxide or potassium hydroxide solution. The
performance of the modified catalysts was tested in the metathesis of
ethylene and trans-2-butene to propylene. During ion exchange,
sodium and potassium ions played different roles. Sodium modified
catalysts revealed constant trans-2-butene conversion and propylene
selectivity when the concentrations of sodium in the solution were
varied. In contrast, potassium modified catalysts showed reduction of
the conversion and increase of the selectivity. From these results,
potassium hydroxide may affect the transformation of tungsten oxide
active species, resulting in the decrease in conversion whereas
sodium hydroxide did not. Moreover, the modification of catalysts by
this method improved the catalyst stability by lowering the amount of
coke deposited on the catalyst surface.
Abstract: This paper deals with the study of reflection and
transmission characteristics of acoustic waves at the interface of a
semiconductor half-space and elastic solid. The amplitude ratios
(reflection and transmission coefficients) of reflected and transmitted
waves to that of incident wave varying with the incident angles have
been examined for the case of quasi-longitudinal wave. The special
cases of normal and grazing incidence have also been derived with
the help of Gauss elimination method. The mathematical model
consisting of governing partial differential equations of motion and
charge carriers’ diffusion of n-type semiconductors and elastic solid
has been solved both analytically and numerically in the study. The
numerical computations of reflection and transmission coefficients
has been carried out by using MATLAB programming software for
silicon (Si) semiconductor and copper elastic solid. The computer
simulated results have been plotted graphically for Si
semiconductors. The study may be useful in semiconductors,
geology, and seismology in addition to surface acoustic wave (SAW)
devices.
Abstract: Optical biosensors have become a powerful detection
and analysis tool for wide-ranging applications in biomedical research,
pharmaceuticals and environmental monitoring. This study carried out
the computational fluid dynamics (CFD)-based simulations to explore
the dispersion phenomenon in the micro channel of an optical
biosensor. The predicted time sequences of concentration contours
were utilized to better understand the dispersion development occurred
in different geometric shapes of micro channels. The simulation results
showed the surface concentrations at the sensing probe (with the best
performance of a grating coupler) in respect of time to appraise the
dispersion effect and therefore identify the design configurations
resulting in minimum dispersion.
Abstract: Water miscible cutting fluids are conventionally used to lubricate and cool the machining zone. But issues related to health hazards, maintenance and disposal costs have limited their usage, leading to application of Minimum Quantity Lubrication (MQL). To increase the effectiveness of MQL, nanocutting fluids are proposed. In the present work, water miscible nanographite cutting fluids of varying concentration are applied at cutting zone by two systems A and B. System A utilizes high pressure air and supplies cutting fluid at a flow rate of 1ml/min. System B uses low pressure air and supplies cutting fluid at a flow rate of 5ml/min. Their performance in machining is evaluated by measuring cutting temperatures, tool wear, cutting forces and surface roughness and compared with dry machining and flood machining. Application of nanocutting fluid using both systems showed better performance than dry machining. Cutting temperatures and cutting forces obtained by both techniques are more than flood machining. But tool wear and surface roughness showed improvement compared to flood machining. Economic analysis has been carried out in all the cases to decide the applicability of the techniques.
Abstract: On the basis of the theory of nonlinear elasticity, the
effect of homogeneous stress on the propagation of Lamb waves in
an initially isotropic hyperelastic plate is analysed. The equations
governing the propagation of small amplitude waves in the prestressed
plate are derived using the theory of small deformations
superimposed on large deformations. By enforcing traction free
boundary conditions at the upper and lower surfaces of the plate,
acoustoelastic dispersion equations for Lamb wave propagation are
obtained, which are solved numerically. Results are given for an
aluminum plate subjected to a range of applied stresses.
Abstract: There are many perceived advantages of microwave
ablation have driven researchers to develop innovative antennas to
effectively treat deep-seated, non-resectable hepatic tumors. In this
paper a coaxial antenna with a miniaturized sleeve choke has been
discussed for microwave interstitial ablation therapy, in order to
reduce backward heating effects irrespective of the insertion depth
into the tissue. Two dimensional Finite Element Method (FEM) is
used to simulate and measure the results of miniaturized sleeve choke
antenna. This paper emphasizes the importance of factors that can
affect simulation accuracy, which include mesh resolution, surface
heating and reflection coefficient. Quarter wavelength choke
effectiveness has been discussed by comparing it with the unchoked
antenna with same dimensions.
Abstract: Removal of the widespread used drug paracetamol
from water was investigated using activated carbon originated from
dende coconut mesocarp and babassu coconut mesocarp. Kinetic and
equilibrium data were obtained at different values of pH. Both
activated carbons showed high efficiency when pH ≤ pHPZC as the
carbonil group of paracetamol molecule are adsorbed due to
positively charged carbon surface. Microporosity also played an
important role in such process. Pseudo-second order model was better
adjusted to the kinetic results. Equilibrium data may be represented
by Langmuir equation.
Abstract: The aim of this study is to investigate formability of
Al based closed cell metallic foams at high temperature. The foam
specimens with rectangular section were produced from
AlMg1Si0.6TiH20.8 alloy preform material. Bending and free
bending tests based on gravity effect were applied to foam specimens
at high temperatures. During the tests, the time-angular deformation
relationships with various temperatures were determined.
Deformation types formed in cell walls were investigated by means
of Scanning Electron Microscopy (SEM) and optical microscopy.
Bending deformation about 90° was achieved without any defect at
high temperatures. The importance of a critical temperature and
deformation rate was emphasized in maintaining the deformation.
Significant slip lines on surface of cell walls at tensile zones of
bending specimen were observed. At high strain rates, the microcrack
formation in boundaries of elongated grains was determined.
Abstract: This paper presents a numerical investigation of two
horizontally mounted four-lobed swirl pipes in terms of swirl
induction effectiveness into flows passing through them. The swirl
flows induced by the two swirl pipes have the potential to improve
the efficiency of Clean-In-Place procedures in a closed processing
system by local intensification of hydrodynamic impact on the
internal pipe surface. Pressure losses, swirl development within the
two swirl pipe, swirl induction effectiveness, swirl decay and wall
shear stress variation downstream of two swirl pipes are analyzed and
compared. It was found that a shorter length of swirl inducing pipe
used in joint with transition pipes is more effective in swirl induction
than when a longer one is used, in that it has a less constraint to the
induced swirl and results in slightly higher swirl intensity just
downstream of it with the expense of a smaller pressure loss. The
wall shear stress downstream of the shorter swirl pipe is also slightly
larger than that downstream of the longer swirl pipe due to the
slightly higher swirl intensity induced by the shorter swirl pipe. The
advantage of the shorter swirl pipe in terms of swirl induction is more
significant in flows with a larger Reynolds Number.
Abstract: Plasmin plays an important role in the human
circulatory system owing to its catalytic ability of fibrinolysis. The
immediate injection of plasmin in patients of strokes has intrigued
many scientists to design vectors that can transport plasmin to the
desired location in human body. Here we predict the structure of
human plasmin and investigate the interaction of plasmin with the
gold-nanoparticle.
Because the crystal structure of plasminogen has been solved, we
deleted N-terminal domain (Pan-apple domain) of plasminogen and
generate a mimic of the active form of this enzyme (plasmin). We
conducted a simulated annealing process on plasmin and discovered a
very large conformation occurs. Kringle domains 1, 4 and 5 had been
observed to leave its original location relative to the main body of the
enzyme and the original doughnut shape of this enzyme has been
transformed to a V-shaped by opening its two arms. This observation
of conformational change is consistent with the experimental results of
neutron scattering and centrifugation.
We subsequently docked the plasmin on the simulated gold surface
to predict their interaction. The V-shaped plasmin could utilize its
Kringle domain and catalytic domain to contact the gold surface.
Our findings not only reveal the flexibility of plasmin structure but
also provide a guide for the design of a plasmin-gold nanoparticle.
Abstract: Brass terminal, one of the several crude oil and
petroleum products storage/handling facilities in the Niger Delta was
built in the 1980s. Activities at this site, over the years, released
crude oil into this 3 m-deep, 1500 m-long canal lying adjacent to the
terminal with oil floating on it and its sediment heavily polluted. To
ensure effective clean-up, three major activities were planned: site
characterization, bioremediation pilot plant construction and testing
and full-scale bioremediation of contaminated sediment / bank soil by
land farming. The canal was delineated into 12 lots and each
characterized, with reference to the floating oily phase, contaminated
sediment and canal bank soil. As a result of site characterization, a
pilot plant for on-site bioremediation was designed and a treatment
basin constructed for carrying out pilot bioremediation test.
Following a designed sampling protocol, samples from this pilot
plant were collected for analysis at two laboratories as a quality
assurance / quality control check. Results showed that Brass Canal
upstream is contaminated with dark, thick and viscous oily film with
characteristic hydrocarbon smell while downstream, thin oily film
interspersed with water was observed. Sediments were observed to be
dark with mixture of brownish sandy soil with TPH ranging from
17,800 mg/kg in Lot 1 to 88,500 mg/kg in Lot 12 samples. Brass
Canal bank soil was observed to be sandy from ground surface to 3m,
below ground surface (bgs) it was silty-sandy and brownish while
subsurface soil (4-10m bgs) was sandy-clayey and whitish/grayish
with typical hydrocarbon smell. Preliminary results obtained so far
have been very promising but were proprietary. This project is
considered, to the best of technical literature knowledge, the first
large-scale on-site bioremediation project in the Niger Delta region,
Nigeria.
Abstract: In wastewater treatment processes, aeration introduces
air into a liquid. In these systems, air is introduced by different
devices submerged in the wastewater. Smaller bubbles result in more
bubble surface area per unit of volume and higher oxygen transfer
efficiency. Jet pumps are devices that use air bubbles and are widely
used in wastewater treatment processes. The principle of jet pumps is
their ability to transfer energy of one fluid, called primary or motive,
into a secondary fluid or gas. These pumps have no moving parts and
are able to work in remote areas under extreme conditions. The
objective of this work is to study experimentally the characteristics of
the jet pump and the size of air bubbles in the laboratory water tank.
The effect of flow rate ratio on pump performance is investigated in
order to have a better understanding about pump behavior under
various conditions, in order to determine the efficiency of receiving
air bubbles different sizes. The experiments show that we should take
care when increasing the flow rate ratio while seeking to decrease
bubble size in the outlet flow. This study will help improve and
extend the use of the jet pump in many practical applications.
Abstract: All current experimental methods for determination of
stress intensity factors are based on the assumption that the state of
stress near the crack tip is plane stress. Therefore, these methods rely
on strain and displacement measurements made outside the near
crack tip region affected by the three-dimensional effects or by
process zone. In this paper, we develop and validate an experimental
procedure for the evaluation of stress intensity factors from the
measurements of the out-of-plane displacements in the surface area
controlled by 3D effects. The evaluation of stress intensity factors is
possible when the process zone is sufficiently small, and the
displacement field generated by the 3D effects is fully encapsulated
by K-dominance region.