Abstract: The DNA microarray technology concurrently monitors the expression levels of thousands of genes during significant biological processes and across the related samples. The better understanding of functional genomics is obtained by extracting the patterns hidden in gene expression data. It is handled by clustering which reveals natural structures and identify interesting patterns in the underlying data. In the proposed work clustering gene expression data is done through an Advanced Nelder Mead (ANM) algorithm. Nelder Mead (NM) method is a method designed for optimization process. In Nelder Mead method, the vertices of a triangle are considered as the solutions. Many operations are performed on this triangle to obtain a better result. In the proposed work, the operations like reflection and expansion is eliminated and a new operation called spread-out is introduced. The spread-out operation will increase the global search area and thus provides a better result on optimization. The spread-out operation will give three points and the best among these three points will be used to replace the worst point. The experiment results are analyzed with optimization benchmark test functions and gene expression benchmark datasets. The results show that ANM outperforms NM in both benchmarks.
Abstract: Measuring the effect of perinatal lead exposure on learning ability of offspring is considered as a sensitive and selective index for providing an early marker for central nervous system damage produced by this toxic metal. A total of 35 Sprague-Dawley adult rats were used to investigate the effect of lead acetate toxicity on behavioral patterns of adult female rats and learning ability of offspring. Rats were allotted into 4 groups, group one received 1g/l lead acetate (n=10), group two received 1.5g/l lead acetate (n=10), group three received 2g/l lead acetate in drinking water (n=10) and control group did not receive lead acetate (n=5) from 8th day of pregnancy till weaning of pups.
The obtained results revealed a dose dependent increase in the feeding time, drinking frequency, licking frequency, scratching frequency, licking litters, nest building and retrieving frequencies, while standing time increased significantly in rats treated with 1.5g/l lead acetate than other treated groups and control, on contrary lying time decreased gradually in a dose dependent manner. Moreover, movement activities were higher in rats treated with 1g/l lead acetate than other treated groups and control. Furthermore, time spent in closed arms was significantly lower in rats given 2g/l lead acetate than other treated groups, while, they spent significantly much time spent in open arms than other treated groups which could be attributed to occurrence of adaptation. Furthermore, number of entries in open arms was dose dependent. However, the ratio between open/closed arms revealed a significant decrease in rats treated with 2g/l lead acetate than control group.
Abstract: In order to better understand the performance of
screen channel liquid acquisition devices (LADs) in liquid oxygen (LOX), a computational fluid dynamics (CFD) simulation of LOX passing through a LAD screen channel was conducted. In the
simulation, the screen is taken as a 'porous jump' where the pressure
drop across the screen depends on the incoming velocity and is formulated by Δp = Av + Bv2
. The CFD simulation reveals the importance of the pressure losses due to the flow entering from
across the screen and impacting and merging with the channel flow
and the vortices in the channel to the cumulative flow resistance. In fact, both the flow resistance of flows impact and mergence and the
resistance created by vortices are much larger than the friction and dynamic pressure losses in the channel and are comparable to the
flow resistance across the screen. Therefore, these resistances in the
channel must be considered as part of the evaluation for the LAD
channel performance. For proper operation of a LAD in LOX these resistances must be less than the bubble point pressure for the screen
channel in LOX. The simulation also presents the pressure and velocity distributions within the LAD screen channel, expanding the understanding of the fluid flow characteristics within the channel.
Abstract: Current advancements in nanotechnology are dependent
on the capabilities that can enable nano-scientists to extend their eyes
and hands into the nano-world. For this purpose, a haptics (devices
capable of recreating tactile or force sensations) based system for
AFM (Atomic Force Microscope) is proposed. The system enables
the nano-scientists to touch and feel the sample surfaces, viewed
through AFM, in order to provide them with better understanding of
the physical properties of the surface, such as roughness, stiffness and
shape of molecular architecture. At this stage, the proposed work uses
of ine images produced using AFM and perform image analysis to
create virtual surfaces suitable for haptics force analysis. The research
work is in the process of extension from of ine to online process
where interaction will be done directly on the material surface for
realistic analysis.
Abstract: Autism Spectrum Disorders (ASDs) are characterized
by abnormalities in social interaction and communication, as well as
repetitive and stereotyped behaviors. Although various studies have
been conducted in ASDs etiology across the world, it seems that they
are still unknown in Middle East. Some scientific researches have
been conducted on ASDs in Middle East (ME) especially in
Kingdom of Saudi Arabia (KSA).
A systematic literature review was performed to identify the ASDs
studies in KSA. Accordingly, PubMed, ISI web of Science and
Google were searched to find KSA and ME studies in ASDs. The
main focus of this review work is to outline an improved
understanding of the underpinnings of ASD in order to achieve
therapeutic interventions and we will discuss the main problem we
waiting for solution with reference with role of Transcranial
Magnetic Stimulation (TMS) to modulate cortical activity improve
understanding ASD.
Abstract: Despite the fact that Knowledge Sharing (KS) is very important, we found only little discussion about the reasons why people have the willingness to share knowledge at such platform even though there is no immediate benefit to the persons who contribute knowledge in it. The aim of this study is to develop an integrative understanding of the factors that support or inhibit individuals- knowledge sharing intentions in virtual communities and to find whether habit would generate people-s willingness to be involved. We apply Social Capital Theory (SCT), and we also add two dimensions for discussion: member incentive and habitual domain (HD). This research assembles the questionnaire from individuals who have experienced knowledge sharing in virtual communities, and applies survey and Structural Equation Model (SEM) to analyze the results from the questionnaires. Finally, results confirm that individuals are willing to share knowledge in virtual communities: (1) if they consider reciprocity, centrality, and have longer tenure in their field, and enjoy helping. (2) if they have the habit of sharing knowledge. This study is useful for the developers of virtual communities to insight into knowledge sharing in cyberspace.
Abstract: Spatial understanding and the understanding of
dynamic change in the spatial structure of molecules during a
reaction is essential for designing new molecules. Knowing the
physical processes in the reactions helps to speed up the designing
process. To support the designer with the correct representation of
the designed molecule as well as showing the dynamic behavior of
the whole reacting system is the goal of our application. Our system
shows the spatial deformation of the molecules at every time interval
by minimizing the energy level of the molecules. The position and
orientation of the molecules can be intuitively controlled by
manipulating objects of the real world using Augmented Reality
techniques. Our approach has the potential to speed up the design of
new molecules and help students to understand the chemical
processes better.
Abstract: In the present paper the extreme shear stresses with the corresponding planes are established using the freely available computer tools like the Gnuplot, Sage, R, Python and Octave. In order to support these freely available computer tools, their strong symbolical and graphical abilities are illustrated. The nature of the stationary points obtained by the Method of Lagrangian Multipliers can be determined using freely available computer symbolical tools like Sage. The characters of the stationary points can be explained in the easiest way using freely available computer graphical tools like Gnuplot, Sage, R, Python and Octave. The presented figures improve the understanding of the problem and the obtained solutions for the majority of students of civil or mechanical engineering.
Abstract: In this work we report the recent progresses that have been achieved by our group in the last half decade on the field of computational proteomics. Specifically, we discuss the application of Molecular Dynamics Simulations and Electronic Structure Calculations in drug design, in the clarification of the structural and dynamic properties of proteins and enzymes and in the understanding of the catalytic and inhibition mechanism of cancer-related enzymes. A set of examples illustrate the concepts and help to introduce the reader into this important and fast moving field.
Abstract: This qualitative, quantitative mixed-method study explores how students- motivation and interest in creative hands-on activities affected their conceptual understanding of science. The objectives of this research include developing a greater understanding about how creative activities, incorporated into the classroom as instructional strategies, increase student motivation and their learning or mastery of science concepts. The creative activities are viewed as a motivational tool, a specific type of task, which have an impact on student goals. Pre-and-post tests, pre-and-post interviews, and student responses measure motivational-goal theory variables, interest in the activity, and conceptual change. Implications for education and future research will be discussed.
Abstract: In this paper the authors present the framework of a
system for assisting users through counseling on personal health, the
Personal Health Assistance Service Expert System (PHASES).
Personal health assistance systems need Personal Health Records
(PHR), which support wellness activities, improve the understanding
of personal health issues, enable access to data from providers of
health services, strengthen health promotion, and in the end improve
the health of the population. This is especially important in societies
where the health costs increase at a higher rate than the overall
economy. The most important elements of a healthy lifestyle are
related to food (such as balanced nutrition and diets), activities for
body fitness (such as walking, sports, fitness programs), and other
medical treatments (such as massage, prescriptions of drugs). The
PHASES framework uses an ontology of food, which includes
nutritional facts, an expert system keeping track of personal health
data that are matched with medical treatments, and a comprehensive
data transfer between patients and the system.
Abstract: The development of wireless communication technologies has changed our living style in global level. After the international success of mobile telephony standards, the location and time independent voice connection has become a default method in daily telecommunications. As for today, highly advanced multimedia messaging plays a key role in value added service handling. Along with evolving data services, the need for more complex applications can be seen, including the mobile usage of broadcast technologies. Here performance of a system design for terrestrial multimedia content is examined with emphasis on mobile reception. This review paper has accommodated the understanding of physical layer role and the flavour of terrestrial channel effects on the terrestrial multimedia transmission using OFDM keeping DVB-H as benchmark standard.
Abstract: This paper addresses the fundamental requirements for
starting an online business. It covers the process of ideation,
conceptualization, formulation, and implementation of new venture
ideas on the Web. Using Facebook as an illustrative example, we learn
how to turn an idea into a successful electronic business and to execute
a business plan with IT skills, management expertise, a good
entrepreneurial attitude, and an understanding of Internet culture. The
personality traits and characteristics of a successful e-commerce
entrepreneur are discussed with reference to Facebook-s founder,
Mark Zuckerberg. Facebook is a social and e-commerce success. It
provides a trusted environment of which participants can conduct
business with social experience. People are able to discuss products
before, during the after the sale within the Facebook environment. The
paper also highlights the challenges and opportunities for e-commerce
entrepreneurial startups to go public and of entering the China market.
Abstract: one of the significant factors for improving the
accuracy of Land Surface Temperature (LST) retrieval is the correct
understanding of the directional anisotropy for thermal radiance. In
this paper, the multiple scattering effect between heterogeneous
non-isothermal surfaces is described rigorously according to the
concept of configuration factor, based on which a directional thermal
radiance model is built, and the directional radiant character for urban
canopy is analyzed. The model is applied to a simple urban canopy
with row structure to simulate the change of Directional Brightness
Temperature (DBT). The results show that the DBT is aggrandized
because of the multiple scattering effects, whereas the change range of
DBT is smoothed. The temperature difference, spatial distribution,
emissivity of the components can all lead to the change of DBT. The
“hot spot" phenomenon occurs when the proportion of high
temperature component in the vision field came to a head. On the other
hand, the “cool spot" phenomena occur when low temperature
proportion came to the head. The “spot" effect disappears only when
the proportion of every component keeps invariability. The model
built in this paper can be used for the study of directional effect on
emissivity, the LST retrieval over urban areas and the adjacency effect
of thermal remote sensing pixels.
Abstract: In any trust model, the two information sources that a peer relies on to predict trustworthiness of another peer are direct experience as well as reputation. These two vital components evolve over time. Trust evolution is an important issue, where the objective is to observe a sequence of past values of a trust parameter and determine the future estimates. Unfortunately, trust evolution algorithms received little attention and the proposed algorithms in the literature do not comply with the conditions and the nature of trust. This paper contributes to this important problem in the following ways: (a) presents an algorithm that manages and models trust evolution in a P2P environment, (b) devises new mechanisms for effectively maintaining trust values based on the conditions that influence trust evolution , and (c) introduces a new methodology for incorporating trust-nurture incentives into the trust evolution algorithm. Simulation experiments are carried out to evaluate our trust evolution algorithm.
Abstract: Aim of this paper is to explore the prospect of a new approach of mobile phone banking in Libya. This study evaluates customer knowledge on commercial mobile banking in Libya. To examine the relationship between age, occupation and intention for using mobile banking for commercial purpose, a survey was conducted to gather information from one hundred Libyan bank clients. The results indicate that Libyan customers have accepted the new technology and they are ready to use it. There is no significant joint relationship between age and occupation found in intention to use mobile banking in Libya. On the other hand, the customers’ knowledge about mobile banking has a greater relationship with the intention. This study has implications for demographic researches and consumer behaviour disciplines. It also has profitable implications for banks and managers in Libya, as it will assist in better understanding of the Libyan consumers and their activities, when they develop their market strategies and new service.
Abstract: The structural interpretation of a part of eastern Potwar
(Missa Keswal) has been carried out with available seismological,
seismic and well data. Seismological data contains both the source
parameters and fault plane solution (FPS) parameters and seismic data
contains ten seismic lines that were re-interpreted by using well data.
Structural interpretation depicts two broad types of fault sets namely,
thrust and back thrust faults. These faults together give rise to pop up
structures in the study area and also responsible for many structural
traps and seismicity. Seismic interpretation includes time and depth
contour maps of Chorgali Formation while seismological interpretation
includes focal mechanism solution (FMS), depth, frequency,
magnitude bar graphs and renewal of Seismotectonic map. The Focal
Mechanism Solutions (FMS) that surrounds the study area are
correlated with the different geological and structural maps of the area
for the determination of the nature of subsurface faults. Results of
structural interpretation from both seismic and seismological data
show good correlation. It is hoped that the present work will help in
better understanding of the variations in the subsurface structure and
can be a useful tool for earthquake prediction, planning of oil field and
reservoir monitoring.
Abstract: This research was to study on background and social
and cultural context of Kamchanoad community for sustainable
tourism management. All data was collected through in-depth
interview with village headmen, community committees, teacher,
monks, Kamchanoad forest field officers and respected senior citizen
above 60 years old in the community who have lived there for more
than 40 years. Altogether there were 30 participants for this research.
After analyzing the data, content from interview and discussion,
Kamchanoad has both high land and low land in the region as well as
swamps that are very capable of freshwater animals’ conservation.
Kamchanoad is also good for agriculture and animal farming. 80% of
Kamchanoad’s land are forest, freshwater and rice farms.
Kamchanoad was officially set up as community in 1994 as “Baan
Nonmuang”. Inhabitants in Kamchanoad make a living by farming
based on sufficiency economy. They have rice farm, eucalyptus farm,
cassava farm and rubber tree farm. Local people in Kamchanoad still
believe in the myth of Srisutto Naga. They are still religious and love
to preserve their traditional way of life. In order to understand how to
create successful tourism business in Kamchanoad, we have to study
closely on local culture and traditions. Outstanding event in
Kamchanoad is the worship of Grand Srisutto, which is on the fullmoon
day of 6th month or Visakhabucha Day. Other big events are
also celebration at the end of Buddhist lent, Naga firework, New
Year celebration, Boon Mahachart, Songkran, Buddhist Lent, Boon
Katin and Loy Kratong. Buddhism is the main religion in
Kamchanoad. The promotion of tourism in Kamchanoad is expected
to help spreading more income for this region. More infrastructures
will be provided for local people as well as funding for youth support
and people activities.
Abstract: The purposes of this study are 1) to study the impact
of the 3-community-core model: House (H), Temple (T), and School
(S) with the co-operation of official departments on community
development to ASEAN economic community involvement and 2) to
study the procedures and extension of the model. The research which
is a qualitative research is based on the formal and informal
interviews. Local people in a community are observed. Group
interview is, also, operated by executors and cooperators in the
school in the community. In terms of social and cultural dimension,
the 3-community-core model consisting of house, temple and school
is the base of Thai cultures bringing about understanding, happiness
and unity to the community. The result of this research is that the
official departments in accompanied with this model developers
cooperatively work together in the community to support such factors
as budget, plan, activities. Moreover, the need of community, and the
continual result to sustain the community are satisfied by the model
implementation. In terms of the procedures of the model
implementation, executors and co-operators can work, coordinate,
think, and launch their public relation altogether. Concerning the
model development, this enables the community to achieve its goal to
prepare the community’s readiness for ASEAN Economic
Community involvement.
Abstract: This paper describes the evolution of strategies to
evaluate ePortfolios in an online Master-s of Education (M.Ed.)
degree in Instructional Technology. The ePortfolios are required as a
culminating activity for students in the program. By using Web 2.0
tools to develop the ePortfolios, students are able to showcase their
technical skills, integrate national standards, demonstrate their
professional understandings, and reflect on their individual learning.
Faculty have created assessment strategies to evaluate student
achievement of these skills. To further develop ePortfolios as a tool
promoting authentic learning, faculty are moving toward integrating
transparency as part of the evaluation process.