Abstract: The potential neuroprotective effect of Phyllantus
nuriri against Fe2+ and sodium nitroprusside (SNP) induced oxidative
stress in mitochondria of rats brain was evaluated. Cellular viability
was assessed by MTT reduction, reactive oxygen species (ROS)
generation was measured using the probe 2,7-dichlorofluoresce
indiacetate (DCFH-DA). Glutathione content was measured using
dithionitrobenzoic acid (DTNB). Fe2+ (10μM) and SNP (5μM)
significantly decreased mitochondrial activity, assessed by MTT
reduction assay, in a dose-dependent manner, this occurred in parallel
with increased glutathione oxidation, ROS production and lipid
peroxidation end-products (thiobarbituric acid reactive substances,
TBARS). The co-incubation with methanolic extract of Phyllantus
nuriri (10-200 μg/ml) reduced the disruption of mitochondrial
activity, gluthathione oxidation, ROS production as well as the
increase in TBARS levels caused by both Fe2+ and SNP in a dose
dependent manner. HPLC analysis of the extract revealed the
presence of gallic acid (20.540.01), caffeic acid (7.930.02), rutin
(25.310.05), quercetin (31.280.03) and kaemferol (14.360.01).
This result suggests that these phytochemicals account for the
protective actions of P. niruri against Fe2+ and SNP -induced
oxidative stress. Our results show that P. nuriri consist important
bioactive molecules in the search for an improved therapy against the
deleterious effects of Fe2+, an intrinsic producer of reactive oxygen
species (ROS), that leads to neuronal oxidative stress and
neurodegeneration.
Abstract: Latin hypercube designs (LHDs) have been applied in
many computer experiments among the space-filling designs found in
the literature. A LHD can be randomly generated but a randomly
chosen LHD may have bad properties and thus act poorly in
estimation and prediction. There is a connection between Latin
squares and orthogonal arrays (OAs). A Latin square of order s
involves an arrangement of s symbols in s rows and s columns, such
that every symbol occurs once in each row and once in each column
and this exists for every non-negative integer s. In this paper, a
computer program was written to construct orthogonal array-based
Latin hypercube designs (OA-LHDs). Orthogonal arrays (OAs) were
constructed from Latin square of order s and the OAs constructed
were afterward used to construct the desired Latin hypercube designs
for three input variables for use in computer experiments. The LHDs
constructed have better space-filling properties and they can be used
in computer experiments that involve only three input factors.
MATLAB 2012a computer package (www.mathworks.com/) was
used for the development of the program that constructs the designs.
Abstract: One of the main challenges in using the Discrete
Element Method (DEM) is to specify the correct input parameter
values. In general, the models are sensitive to the input parameter
values and accurate results can only be achieved if the correct values
are specified. For the linear contact model, micro-parameters such as
the particle density, stiffness, coefficient of friction, as well as the
particle size and shape distributions are required. There is a need for
a procedure to accurately calibrate these parameters before any
attempt can be made to accurately model a complete bulk materials
handling system. Since DEM is often used to model applications in
the mining and quarrying industries, a calibration procedure was
developed for materials that consist of relatively large (up to 40 mm
in size) particles. A coarse crushed aggregate was used as the test
material. Using a specially designed large shear box with a diameter
of 590 mm, the confined Young’s modulus (bulk stiffness) and
internal friction angle of the material were measured by means of the
confined compression test and the direct shear test respectively. DEM
models of the experimental setup were developed and the input
parameter values were varied iteratively until a close correlation
between the experimental and numerical results was achieved. The
calibration process was validated by modelling the pull-out of an
anchor from a bed of material. The model results compared well with
experimental measurement.
Abstract: This paper investigates the benefits of deliberately
unbalancing both operation time means (MTs) and unreliability
(failure and repair rates) for non-automated production lines. The
lines were simulated with various line lengths, buffer capacities,
degrees of imbalance and patterns of MT and unreliability imbalance.
Data on two performance measures, namely throughput (TR) and
average buffer level (ABL) were gathered, analyzed and compared to
a balanced line counterpart. A number of conclusions were made
with respect to the ranking of configurations, as well as to the
relationships among the independent design parameters and the
dependent variables. It was found that the best configurations are a
balanced line arrangement and a monotone decreasing MT order,
coupled with either a decreasing or a bowl unreliability configuration,
with the first generally resulting in a reduced TR and the second
leading to a lower ABL than those of a balanced line.
Abstract: The strawberry tree (Arbutus unedo L.) is a small tree
or shrub from botanical Ericaceae family that grows spontaneously
nearby the Mediterranean basin and produce edible red fruits. A
traditional processed fruit application, in Mediterranean countries, is
the production of a spirit (known as aguardente de medronho, in
Portugal) obtained from the fermented fruit. The main objective of
our study was to contribute to the knowledge about the influence of
the degree of maturation of fruits in the volatile composition and
quality of arbutus spirit. The major volatiles in the three distillates
fractions (head, heart and tail) obtained from fermentation of two
different fruit maturation levels were quantified by GC-FID analysis
and ANOVA one-way was performed. Additionally, the total
antioxidant capacity and total phenolic compounds of both arbutus
fruit spirits were determined, by ABTS and Folin-Ciocalteau method,
respectively. The methanol concentration is higher (1022.39 g/hL
a.a.) in the spirit made from fruits with highest total soluble solids,
which is a value above the legal limit (1000 g/hL a.a.). Overall, our
study emphasizes, for the first time, the influence of maturation
degree of arbutus fruits in the spirit volatile composition and quality.
Abstract: The present study was carried out to investigate the
effect of alloying elements and thermo-mechanical treatment (TMT)
i.e. hot rolling and forging with different reduction ratios on the
hardness (HV) and impact toughness (J) of heat-treated low alloy
steels. An understanding of the combined effect of TMT and alloying
elements and by measuring hardness, impact toughness, resulting
from different heat treatment following TMT of the low alloy steels,
it is possible to determine which conditions yielded optimum
mechanical properties and high strength to weight ratio.
Experimental Correlations between hot work reduction ratio,
hardness and impact toughness for thermo-mechanically heat treated
low alloy steels are analyzed quantitatively, and both regression and
mathematical hardness and impact toughness models are developed.
Abstract: This paper presents an optimal broadcast algorithm
for the hypercube networks. The main focus of the paper is the
effectiveness of the algorithm in the presence of many node faults.
For the optimal solution, our algorithm builds with spanning tree
connecting the all nodes of the networks, through which messages
are propagated from source node to remaining nodes. At any given
time, maximum n − 1 nodes may fail due to crashing. We show
that the hypercube networks are strongly fault-tolerant. Simulation
results analyze to accomplish algorithm characteristics under many
node faults. We have compared our simulation results between our
proposed method and the Fu’s method. Fu’s approach cannot tolerate
n − 1 faulty nodes in the worst case, but our approach can tolerate
n − 1 faulty nodes.
Abstract: Introduction: There are multiple social, individual and
cultural factors that influence an individual’s decision to adopt family
planning methods especially among non-users in patriarchal societies
like Pakistan. Non-users, if targeted efficiently, can contribute
significantly to country’s CPR. A research study showed that nonusers
if convinced to adopt lactational amenorrhea method can shift
to long term methods in future. Research shows that if non users are
targeted efficiently a 59% reduction in unintended pregnancies in
Saharan Africa and South-Central and South-East Asia is anticipated.
Methods: We did secondary data analysis on Pakistan
Demographic Heath Survey (2012-13) dataset. Use of contraception
(never-use/ever-use) was the outcome variable. At univariate level
Chi-square/Fisher Exact test was used to assess relationship of
baseline covariates with contraception use. Then variables to be
incorporated in the model were checked for multicollinearity,
confounding and interaction. Then binary logistic regression (with an
urban-rural stratification) was done to find relationship between
contraception use and baseline demographic and social variables.
Results: The multivariate analyses of the study showed that
younger women (≤ 29 years)were more prone to be never users as
compared to those who were >30 years and this trend was seen in
urban areas (AOR 1.92, CI 1.453-2.536) as well as rural areas (AOR
1.809, CI 1.421-2.303). While looking at regional variation, women
from urban Sindh (AOR 1.548, CI 1.142-2.099) and urban
Balochistan (AOR 2.403, CI 1.504-3.839) had more never users as
compared to other urban regions. Women in the rich wealth quintile
were more never users and this was seen both in urban and rural
localities (urban (AOR 1.106 CI .753-1.624); rural areas (AOR 1.162,
CI .887-1.524)) even though these were not statistically significant.
Women idealizing more children (>4) are more never users as
compared to those idealizing less children in both urban (AOR 1.854,
CI 1.275-2.697) and rural areas (AOR 2.101, CI 1.514-2.916).
Women who never lost a pregnancy were more inclined to be nonusers
in rural areas (AOR 1.394, CI 1.127-1.723) .Women familiar
with only traditional or no method had more never users in rural areas
(AOR 1.717, CI 1.127-1.723) but in urban areas it wasn’t significant.
Women unaware of Lady Health Worker’s presence in their area
were more never users especially in rural areas (AOR 1.276, CI
1.014-1.607). Women who did not visit any care provider were more
never users (urban (AOR 11.738, CI 9.112-15.121) rural areas (AOR
7.832, CI 6.243-9.826)).
Discussion/Conclusion: This study concluded that government,
policy makers and private sector family planning programs should
focus on the untapped pool of never users (younger women from underserved provinces, in higher wealth quintiles, who desire more
children.). We need to make sure to cover catchment areas where
there are less LHWs and less providers as ignorance to modern
methods and never been visited by an LHW are important
determinants of never use. This all is in sync with previous literate
from similar developing countries.
Abstract: Crosstalk among interconnects and printed-circuit
board (PCB) traces is a major limiting factor of signal quality in highspeed
digital and communication equipments especially when fast
data buses are involved. Such a bus is considered as a planar
multiconductor transmission line. This paper will demonstrate how
the finite difference time domain (FDTD) method provides an exact
solution of the transmission-line equations to analyze the near end
and the far end crosstalk. In addition, this study makes it possible to
analyze the rise time effect on the near and far end voltages of the
victim conductor. The paper also discusses a statistical analysis,
based upon a set of several simulations. Such analysis leads to a
better understanding of the phenomenon and yields useful
information.
Abstract: The effect of N2 pretreatment on the catalytic activity
of tungsten-based catalysts was investigated in the metathesis of
ethylene and trans-2-butene at 450oC and atmospheric pressure. The
presence of tungsten active species was confirmed by UV-Vis and
Raman spectroscopy. Compared to the WO3-based catalysts treated
in air, higher amount of WO4 2-tetrahedral species and lower amount
of WO3 crystalline species were observed on the N2-treated ones.
These contribute to the higher conversion of 2-butene and propylene
selectivity during 10 h time-on-stream. Moreover, N2 treatment led to
lower amount of coke formation as revealed by TPO of the spent
catalysts.
Abstract: This work sets out to debate the tensions involved in
the processes of contamination and self-purification in the urban
space, particularly in the streams that run through the Buenos Aires
metropolitan area. For much of their course, those streams are piped;
their waters do not come into contact with the outdoors until they
have reached deeply impoverished urban areas with high levels of
environmental contamination. These are peripheral zones that, until
thirty years ago, were marshlands and fields. They are now densely
populated areas largely lacking in urban infrastructure.
The Cárcova neighborhood, where this project is underway, is in
the José León Suárez section of General San Martín county, Buenos
Aires province. A stretch of José León Suarez canal crosses the
neighborhood. Starting upstream, this canal carries pollutants due to
the sewage and industrial waste released into it. Further downstream,
in the neighborhood, domestic drainage is poured into the stream. In
this paper, we formulate a hypothesis diametrical to the one that
holds that these neighborhoods are the primary source of
contamination, suggesting instead that in the stretch of the canal that
runs through the neighborhood the stream’s waters are actually
cleaned and the sediments accumulate pollutants. Indeed, the
stretches of water that runs through these neighborhoods act as water
processing plants for the metropolis.
This project has studied the different organic-load polluting
contributions to the water in a certain stretch of the canal, the
reduction of that load over the course of the canal, and the
incorporation of pollutants into the sediments. We have found that
the surface water has considerable ability to self-purify, mostly due to
processes of sedimentation and adsorption. The polluting load is
accumulated in the sediments where that load stabilizes slowly by
means of anaerobic processes. In this study, we also investigated the
risks of sediment management and the use of the processes studied
here in controlled conditions as tools of environmental restoration.
Abstract: This study attempts to identify the factors influencing
on women empowerment of rural area in Sri Lanka through micro
finance services. Data were collected from one hundred (100) rural
women involving self-employment activities through a questionnaire
using direct personal interviews. Judgment and Convenience Random
sampling technique was used to select the sample size from three
Divisional Secretariat divisions of Kandawalai, Poonakari and
Karachchi in Kilinochchi District. The factor analysis was performed
on fourteen (14) variables for screening and reducing the variables to
identify the influencing factors on empowerment. Multiple regression
analysis was used to identify the relationship between the three
empowerment factors and the impact of micro finance on overall
empowerment of rural women. The result of this study summarized
the variables into three factors namely decision making, freedom to
mobility and family support and which are positively associated with
empowerment. In addition to this the value of adjusted R2 is 0.248
indicates that all the variables extracted can be explained 24.8% of
the variation in the women empowerment through microfinance.
Independent variables of these three factors have positive correlation
with women empowerment as well as significant values at 5 percent
level.
Abstract: Quality of Service (QoS) attributes as part of the
service description is an important factor for service attribute. It is not
easy to exactly quantify the weight of each QoS conditions since
human judgments based on their preference causes vagueness. As
web services selection requires optimization, evolutionary computing
based on heuristics to select an optimal solution is adopted. In this
work, the evolutionary computing technique Particle Swarm
Optimization (PSO) is used for selecting a suitable web services
based on the user’s weightage of each QoS values by optimizing the
QoS weight vector and thereby finding the best weight vectors for
best services that is being selected. Finally the results are compared
and analyzed using static inertia weight and deterministic inertia
weight of PSO.
Abstract: The Scheduling and mapping of tasks on a set of
processors is considered as a critical problem in parallel and
distributed computing system. This paper deals with the problem of
dynamic scheduling on a special type of multiprocessor architecture
known as Linear Crossed Cube (LCQ) network. This proposed
multiprocessor is a hybrid network which combines the features of
both linear types of architectures as well as cube based architectures.
Two standard dynamic scheduling schemes namely Minimum
Distance Scheduling (MDS) and Two Round Scheduling (TRS)
schemes are implemented on the LCQ network. Parallel tasks are
mapped and the imbalance of load is evaluated on different set of
processors in LCQ network. The simulations results are evaluated
and effort is made by means of through analysis of the results to
obtain the best solution for the given network in term of load
imbalance left and execution time. The other performance matrices
like speedup and efficiency are also evaluated with the given
dynamic algorithms.
Abstract: Present study is carried out on six lane divided urban
arterial road in Patna and Pune city of India. Both the road having
distinct differences in terms of the vehicle composition and the road
side parking. Arterial road in Patan city has 33% of non-motorized
mode, whereas Pune arterial road dominated by 65% of Two wheeler.
Also road side parking is observed in Patna city. The field studies
using videography techniques are carried out for traffic data
collection. Data are extracted for one minute duration for vehicle
composition, speed variation and flow rate on selected arterial road of
the two cities. Speed flow relationship is developed and capacity is
determine. Equivalency factor in terms of dynamic car unit is
determine to represent the vehicle is single unit. The variation in the
capacity due to side friction, presence of non motorized traffic and
effective utilization of lane width is compared at concluding remarks.
Abstract: The model tests were conducted in the laboratory
without and with Plastic recycled polymer in fly ash steep slopes
overlaying soft foundation soils like fly ash and powai soil in order to
check the stability of steep slope. In this experiment, fly ash is used
as a filling material and Plastic Recycled Polymers of diameter =
3mm and length = 4mm were made from waste plastic product (lower
grade plastic product). The properties of fly ash and Plastic recycled
polymers are determined. From the experiments, load and settlement
have measured. From these data, load –settlement curves have
reported. It has been observed from test results that load carrying
capacity of mixture fly ash with Plastic Recycled Polymers slope is
more than that of fly ash slope. The deformation of Plastic Recycled
Polymers slope is slightly more than that of fly ash slope. A Finite
Element Method (F.E.M.) was also evaluated using PLAXIS 3D
version. The failure pattern, deformations and factor of safety are
reported based on analytical programme. The results from
experimental data and analytical programme are compared and
reported.
Abstract: Due to rapid pressured of population growth, city has
started to lose its old tradition. City becomes congested with
uncomfortably living. Urban renewal refers orderly development of
settlements as well as land redevelopment. For this paper Chittagong
city has been selected as study area. It had a great tradition but it has
been losing its concord. Land use pattern of this place is also
haphazard due to lack of planning intervention. Renewal plan is
needed to ascertain suitable redevelopment and to recommend on
preservation of city heritage structure. The goal of this study is to
prepare a renewal plan using local planning approach. Social impact
methods have been used to achieve this goal. Both primary and
secondary data are used to achieve the goal. This study may find out
a complete solution for healthy living in old Part of city. This study
will help to preserve its tradition and makes urban lives more livable.
Abstract: This study presented to reduce earthquake damage and
emergency rehabilitation of critical structures such as schools, hightech
factories, and hospitals due to strong ground motions associated
with climate changes. Regarding recent trend, a strong earthquake
causes serious damage to critical structures and then the critical
structure might be influenced by sequence aftershocks (or tsunami)
due to fault plane adjustments. Therefore, in order to improve seismic
performance of critical structures, retrofitted or strengthening study
of the structures under aftershocks sequence after emergency
rehabilitation of the structures subjected to strong earthquakes is
widely carried out. Consequently, this study used composite material
for emergency rehabilitation of the structure rather than concrete and
steel materials because of high strength and stiffness, lightweight,
rapid manufacturing, and dynamic performance. Also, this study was
to develop or improve the seismic performance or seismic retrofit of
critical structures subjected to strong ground motions and earthquake
aftershocks, by utilizing GFRP-Corrugated Infill Panels (GCIP).
Abstract: Organizational tendencies towards computer-based
information processing have been observed noticeably in the
third-world countries. Many enterprises are taking major initiatives
towards computerized working environment because of massive
benefits of computer-based information processing. However,
designing and developing information resource management software
for small and mid-size enterprises under budget costs and strict
deadline is always challenging for software engineers. Therefore, we
introduced an approach to design mid-size enterprise software by
using the Waterfall model, which is one of the SDLC (Software
Development Life Cycles), in a cost effective way. To fulfill research
objectives, in this study, we developed mid-sized enterprise software
named “BSK Management System” that assists enterprise software
clients with information resource management and perform complex
organizational tasks. Waterfall model phases have been applied to
ensure that all functions, user requirements, strategic goals, and
objectives are met. In addition, Rich Picture, Structured English, and
Data Dictionary have been implemented and investigated properly in
engineering manner. Furthermore, an assessment survey with 20
participants has been conducted to investigate the usability and
performance of the proposed software. The survey results indicated
that our system featured simple interfaces, easy operation and
maintenance, quick processing, and reliable and accurate transactions.
Abstract: The advent of social networking technologies has been
met with mixed reactions in academic and corporate circles around
the world. This study explored the influence of social network in
current era, the relation being maintained between the Social
networking site and its user by the extent of use, benefits and latest
technologies. The study followed a descriptive research design
wherein a questionnaire was used as the main research tool. The data
collected was analyzed using SPSS 16. Data was gathered from 1205
users and analyzed in accordance with the objectives of the study.
The analysis of the results seem to suggest that the majority of users
were mainly using Facebook, despite of concerns raised about the
disclosure of personal information on social network sites, users
continue to disclose huge quantity of personal information, they find
that reading privacy policy is time consuming and changes made can
result into improper settings.