Abstract: Segmentation, filtering out of measurement errors and
identification of breakpoints are integral parts of any analysis of
microarray data for the detection of copy number variation (CNV).
Existing algorithms designed for these tasks have had some successes
in the past, but they tend to be O(N2) in either computation time or
memory requirement, or both, and the rapid advance of microarray
resolution has practically rendered such algorithms useless. Here we
propose an algorithm, SAD, that is much faster and much less thirsty
for memory – O(N) in both computation time and memory requirement
-- and offers higher accuracy. The two key ingredients of SAD are the
fundamental assumption in statistics that measurement errors are
normally distributed and the mathematical relation that the product of
two Gaussians is another Gaussian (function). We have produced a
computer program for analyzing CNV based on SAD. In addition to
being fast and small it offers two important features: quantitative
statistics for predictions and, with only two user-decided parameters,
ease of use. Its speed shows little dependence on genomic profile.
Running on an average modern computer, it completes CNV analyses
for a 262 thousand-probe array in ~1 second and a 1.8 million-probe
array in 9 seconds
Abstract: I/O workload is a critical and important factor to
analyze I/O pattern and file system performance. However tracing I/O
operations on the fly distributed parallel file system is non-trivial due
to collection overhead and a large volume of data. In this paper, we
design and implement a parallel file system logging method for high
performance computing using shared memory-based multi-layer
scheme. It minimizes the overhead with reduced logging operation
response time and provides efficient post-processing scheme through
shared memory. Separated logging server can collect sequential logs
from multiple clients in a cluster through packet communication.
Implementation and evaluation result shows low overhead and high
scalability of this architecture for high performance parallel logging
analysis.
Abstract: Aluminum salt that is generally presents as a solid
phase in the water purification sludge (WPS) can be dissolved,
recovering a liquid phase, by adding strong acid to the sludge solution.
According to the reaction kinetics, when reactant is in the form of
small particles with a large specific surface area, or when the reaction
temperature is high, the quantity of dissolved aluminum salt or
reaction rate, respectively are high. Therefore, in this investigation,
water purification sludge (WPS) solution was treated with ultrasonic
waves to break down the sludge, and different acids (1 N HCl and 1 N
H2SO4) were used to acidify it. Acid dosages that yielded the solution
pH of less than two were used. The results thus obtained indicate that
the quantity of dissolved aluminum in H2SO4-acidified solution
exceeded that in HCl-acidified solution. Additionally, ultrasonic
treatment increased the rate of dissolution of aluminum and the
amount dissolved. The quantity of aluminum dissolved at 60℃ was 1.5
to 2.0 times higher than that at 25℃.
Abstract: The visualization of geographic information on mobile devices has become popular as the widespread use of mobile Internet. The mobility of these devices brings about much convenience to people-s life. By the add-on location-based services of the devices, people can have an access to timely information relevant to their tasks. However, visual analysis of geographic data on mobile devices presents several challenges due to the small display and restricted computing resources. These limitations on the screen size and resources may impair the usability aspects of the visualization applications. In this paper, a variable-scale visualization method is proposed to handle the challenge of small mobile display. By merging multiple scales of information into a single image, the viewer is able to focus on the interesting region, while having a good grasp of the surrounding context. This is essentially visualizing the map through a fisheye lens. However, the fisheye lens induces undesirable geometric distortion in the peripheral, which renders the information meaningless. The proposed solution is to apply map generalization that removes excessive information around the peripheral and an automatic smoothing process to correct the distortion while keeping the local topology consistent. The proposed method is applied on both artificial and real geographical data for evaluation.
Abstract: A generalized Dirichlet to Neumann map is
one of the main aspects characterizing a recently introduced
method for analyzing linear elliptic PDEs, through which it
became possible to couple known and unknown components
of the solution on the boundary of the domain without
solving on its interior. For its numerical solution, a well conditioned
quadratically convergent sine-Collocation method
was developed, which yielded a linear system of equations
with the diagonal blocks of its associated coefficient matrix
being point diagonal. This structural property, among others,
initiated interest for the employment of iterative methods for
its solution. In this work we present a conclusive numerical
study for the behavior of classical (Jacobi and Gauss-Seidel)
and Krylov subspace (GMRES and Bi-CGSTAB) iterative
methods when they are applied for the solution of the Dirichlet
to Neumann map associated with the Laplace-s equation
on regular polygons with the same boundary conditions on
all edges.
Abstract: The study is aimed to test causal relationship between
growth and unemployment, using time series data for Pakistan from
1972 to 2006. Growth is considered to be a pathway to decrease the
level of unemployment. Unemployment is a social and political
issue. It is a phenomenon where human resources are wasted leading
to deacceleration in growth. Johanson Cointegration shows that there
is long run relationship between growth and unemployment. For
short run dynamics and causality, the study utilizes Vector Error
Correction Model (VECM). The results of VECM indicate that there
is short and long run causal relation between growth and
unemployment including capital, labor and human capital as
explanatory variables.
Abstract: In online context, the design and implementation of
effective remote laboratories environment is highly challenging on
account of hardware and software needs. This paper presents the
remote laboratory software framework modified from ilab shared
architecture (ISA). The ISA is a framework which enables students to
remotely acccess and control experimental hardware using internet
infrastructure. The need for remote laboratories came after
experiencing problems imposed by traditional laboratories. Among
them are: the high cost of laboratory equipment, scarcity of space,
scarcity of technical personnel along with the restricted university
budget creates a significant bottleneck on building required
laboratory experiments. The solution to these problems is to build
web-accessible laboratories. Remote laboratories allow students and
educators to interact with real laboratory equipment located
anywhere in the world at anytime. Recently, many universities and
other educational institutions especially in third world countries rely
on simulations because they do not afford the experimental
equipment they require to their students. Remote laboratories enable
users to get real data from real-time hand-on experiments. To
implement many remote laboratories, the system architecture should
be flexible, understandable and easy to implement, so that different
laboratories with different hardware can be deployed easily. The
modifications were made to enable developers to add more
equipment in ISA framework and to attract the new developers to
develop many online laboratories.
Abstract: Transportation is one of the most fundamental
challenges of urban development in contemporary world. On the
other hand, sustainable urban development has received tremendous
public attention in the last few years. This trend in addition to other
factors such as energy cost, environmental concerns, traffic
congestion and the feeling of lack of belonging have contributed to
the development of pedestrian areas. The purpose of this paper is to
study the role of walkable streets in sustainable development of
cities. Accordingly, a documentary research through valid sources
has been utilized to substantiate this study. The findings demonstrate
that walking can lead to sustainable urban development from
physical, social, environmental, cultural, economic and political
aspects. Also, pedestrian areas –which are the main context of
walking- act as focal points of development in cities and have a great
effect on modifying and stimulating of their adjacent urban spaces.
Abstract: Polymer-like organic thin films were deposited on both
aluminum alloy type 6061 and glass substrates at room temperature by
Plasma Enhanced Chemical Vapor Deposition (PECVD) methodusing
benzene and hexamethyldisiloxane (HMDSO) as precursor materials.
The surface and physical properties of plasma-polymerized organic
thin films were investigated at different r.f. powers. The effects of
benzene/argon ratio on the properties of plasma polymerized benzene
films were also investigated. It is found that using benzene alone
results in a non-coherent and non-adherent powdery deposited
material. The chemical structure and surface properties of the asgrown
plasma polymerized thin films were analyzed on glass
substrates with FTIR and contact angle measurements. FTIR spectra
of benzene deposited film indicated that the benzene rings are
preserved when increasing benzene ratio and/or decreasing r.f.
powers. FTIR spectra of HMDSO deposited films indicated an
increase of the hydrogen concentration and a decrease of the oxygen
concentration with the increase of r.f. power. The contact angle (θ) of
the films prepared from benzene was found to increase by about 43%
as benzene ratio increases from 10% to 20%. θ was then found to
decrease to the original value (51°) when the benzene ratio increases
to 100%. The contact angle, θ, for both benzene and HMDSO
deposited films were found to increase with r.f. power. This signifies
that the plasma polymerized organic films have substantially low
surface energy as the r.f power increases. The corrosion resistance of
aluminum alloy substrate both bare and covered with plasma
polymerized thin films was carried out by potentiodynamic
polarization measurements in standard 3.5 wt. % NaCl solution at
room temperature. The results indicate that the benzene and HMDSO
deposited films are suitable for protection of the aluminum substrate
against corrosion. The changes in the processing parameters seem to
have a strong influence on the film protective ability. Surface
roughness of films deposited on aluminum alloy substrate was
investigated using scanning electron microscopy (SEM). The SEM
images indicate that the surface roughness of benzene deposited films
increase with decreasing the benzene ratio. SEM images of benzene
and HMDSO deposited films indicate that the surface roughness
decreases with increasing r.f. power. Studying the above parameters
indicate that the films produced are suitable for specific practical
applications.
Abstract: Tubular process equipment is often damaged in
industrial processes. The damage occurs both on devices working at
high temperatures and also on less exposed devices. In case of sudden
damage of key equipment a shutdown of the whole production unit
and resulting significant economic losses are imminent. This paper
presents a solution of several types of tubular process equipment. The
causes of damage and suggestions of correction actions are discussed
in all cases. Very important part is the analysis of operational
conditions, determination of unfavourable working states decreasing
lifetime of devices and suggestions of correction actions. Lately very
popular numerical methods are used for analysis of the equipment.
Abstract: Due to the liberalization of countless electricity markets, load forecasting has become crucial to all public utilities for which electricity is a strategic variable. With the goal of contributing to the forecasting process inside public utilities, this paper addresses the issue of applying the Holt-Winters exponential smoothing technique and the time series analysis for forecasting the hourly electricity load curve of the Italian railways. The results of the analysis confirm the accuracy of the two models and therefore the relevance of forecasting inside public utilities.
Abstract: Soursop (Anona muricata) is one of the underutilized tropical fruits containing nutrients, particularly dietary fibre and antioxidant properties that are beneficial to human health. This objective of this study is to investigate the feasibility of matured soursop pulp flour (SPF) to be substituted with high-protein wheat flour in bread. Bread formulation was substituted with different levels of SPF (0%, 5%, 10% and 15%). The effect on physicochemical properties and sensory attributes were evaluated. Higher substitution level of SPF resulted in significantly higher (p
Abstract: It is by reason of the unified measure of varieties of resources and the unified processing of the disposal of varieties of resources, that these closely related three of new basic models called the resources assembled node and the disposition integrated node as well as the intelligent organizing node are put forth in this paper; the three closely related quantities of integrative analytical mechanics including the disposal intensity and disposal- weighted intensity as well as the charge of resource charge are set; and then the resources assembled space and the disposition integrated space as well as the intelligent organizing space are put forth. The system of fundamental equations and model of complete factor synergetics is preliminarily approached for the general situation in this paper, to form the analytical base of complete factor synergetics. By the essential variables constituting this system of equations we should set twenty variables respectively with relation to the essential dynamical effect, external synergetic action and internal synergetic action of the system.
Abstract: The aim of this paper is to introduce a parametric
distribution model in fatigue life reliability analysis dealing with
variation in material properties. Service loads in terms of responsetime
history signal of Belgian pave were replicated on a multi-axial
spindle coupled road simulator and stress-life method was used to
estimate the fatigue life of automotive stub axle. A PSN curve was
obtained by monotonic tension test and two-parameter Weibull
distribution function was used to acquire the mean life of the
component. A Pearson system was developed to evaluate the fatigue
life reliability by considering stress range intercept and slope of the
PSN curve as random variables. Considering normal distribution of
fatigue strength, it is found that the fatigue life of the stub axle to
have the highest reliability between 10000 – 15000 cycles. Taking
into account the variation of material properties associated with the
size effect, machining and manufacturing conditions, the method
described in this study can be effectively applied in determination of
probability of failure of mass-produced parts.
Abstract: Novel polystrene-bound Schiff bases and their Pt(IV)
complexes have been prepared from condensation reaction of
polystyrene-A-NH2 with 2-hydroxybenzaldehyde and 5-fluoro-3-
bromo-2-hydroxybenzaldehyde. The structures of Pt(IV) complexes
with polystyrene including Schiff bases have been determined by
elemental analyses, magnetic susceptibility, IR, 1H-NMR, UV-vis,
TG/DTA and AAS. The antibacterial and antifungal activities of the
synthesized compounds have been studied by the well-diffusion
method against some selected microorganisms: (Bacillus cereus spp.,
Listeria monocytogenes 4b, Micrococcus luteus, Staphylococcus
aureus, Staphylococcus epidermis, Brucella abortus, Escherichia
coli, Pseudomonas putida spp., Shigella dysenteria type 10,
Salmonella typhi H).
Abstract: Pulse code modulation is a widespread technique
in digital communication with significant impact on existing
modern and proposed future communication technologies. Its
widespread utilization is due to its simplicity and attractive
spectral characteristics. In this paper, we present a new
approach to the spectral analysis of PCM signals using
Riemann-Stieltjes integrals, which is very accurate for high bit
rates. This approach can serve as a model for similar spectral
analysis of other competing modulation schemes.
Abstract: Simulations play a major role in education not only because they provide realistic models with which students can interact to acquire real world experiences, but also because they constitute safe environments in which students can repeat processes without any risk in order to perceive easier concepts and theories. Virtual reality is widely recognized as a significant technological advance that can facilitate learning process through the development of highly realistic 3D simulations supporting immersive and interactive features. The objective of this paper is to analyze the influence of virtual reality-s use in chemistry instruction as well as to present an integrated web-based learning environment for the simulation of chemical experiments. The proposed application constitutes a cost-effective solution for both schools and universities without appropriate infrastructure and a valuable tool for distance learning and life-long education in chemistry. Its educational objectives are the familiarization of students with the equipment of a real chemical laboratory and the execution of virtual volumetric analysis experiments with the active participation of students.
Abstract: Music Information Retrieval (MIR) and modern data mining techniques are applied to identify style markers in midi music for stylometric analysis and author attribution. Over 100 attributes are extracted from a library of 2830 songs then mined using supervised learning data mining techniques. Two attributes are identified that provide high informational gain. These attributes are then used as style markers to predict authorship. Using these style markers the authors are able to correctly distinguish songs written by the Beatles from those that were not with a precision and accuracy of over 98 per cent. The identification of these style markers as well as the architecture for this research provides a foundation for future research in musical stylometry.
Abstract: The conventional GA combined with a local search
algorithm, such as the 2-OPT, forms a hybrid genetic algorithm(HGA)
for the traveling salesman problem (TSP). However, the geometric
properties which are problem specific knowledge can be used to
improve the search process of the HGA. Some tour segments (edges)
of TSPs are fine while some maybe too long to appear in a short tour.
This knowledge could constrain GAs to work out with fine tour
segments without considering long tour segments as often.
Consequently, a new algorithm is proposed, called intelligent-OPT
hybrid genetic algorithm (IOHGA), to improve the GA and the 2-OPT
algorithm in order to reduce the search time for the optimal solution.
Based on the geometric properties, all the tour segments are assigned
2-level priorities to distinguish between good and bad genes. A
simulation study was conducted to evaluate the performance of the
IOHGA. The experimental results indicate that in general the IOHGA
could obtain near-optimal solutions with less time and better accuracy
than the hybrid genetic algorithm with simulated annealing algorithm
(HGA(SA)).
Abstract: Fossil fuels are the major source to meet the world
energy requirements but its rapidly diminishing rate and adverse
effects on our ecological system are of major concern. Renewable
energy utilization is the need of time to meet the future challenges.
Ocean energy is the one of these promising energy resources. Threefourths
of the earth-s surface is covered by the oceans. This enormous
energy resource is contained in the oceans- waters, the air above the
oceans, and the land beneath them. The renewable energy source of
ocean mainly is contained in waves, ocean current and offshore solar
energy. Very fewer efforts have been made to harness this reliable
and predictable resource. Harnessing of ocean energy needs detail
knowledge of underlying mathematical governing equation and their
analysis. With the advent of extra ordinary computational resources
it is now possible to predict the wave climatology in lab simulation.
Several techniques have been developed mostly stem from numerical
analysis of Navier Stokes equations. This paper presents a brief over
view of such mathematical model and tools to understand and
analyze the wave climatology. Models of 1st, 2nd and 3rd generations
have been developed to estimate the wave characteristics to assess the
power potential. A brief overview of available wave energy
technologies is also given. A novel concept of on-shore wave energy
extraction method is also presented at the end. The concept is based
upon total energy conservation, where energy of wave is transferred
to the flexible converter to increase its kinetic energy. Squeezing
action by the external pressure on the converter body results in
increase velocities at discharge section. High velocity head then can
be used for energy storage or for direct utility of power generation.
This converter utilizes the both potential and kinetic energy of the
waves and designed for on-shore or near-shore application. Increased
wave height at the shore due to shoaling effects increases the
potential energy of the waves which is converted to renewable
energy. This approach will result in economic wave energy
converter due to near shore installation and more dense waves due to
shoaling. Method will be more efficient because of tapping both
potential and kinetic energy of the waves.