Abstract: Calcium is a vital second messenger used in signal transduction. Calcium controls secretion, cell movement, muscular contraction, cell differentiation, ciliary beating and so on. Two theories have been used to simplify the system of reaction-diffusion equations of calcium into a single equation. One is excess buffer approximation (EBA) which assumes that mobile buffer is present in excess and cannot be saturated. The other is rapid buffer approximation (RBA), which assumes that calcium binding to buffer is rapid compared to calcium diffusion rate. In the present work, attempt has been made to develop a model for calcium diffusion under excess buffer approximation in neuron cells. This model incorporates the effect of [Na+] influx on [Ca2+] diffusion,variable calcium and sodium sources, sodium-calcium exchange protein, Sarcolemmal Calcium ATPase pump, sodium and calcium channels. The proposed mathematical model leads to a system of partial differential equations which have been solved numerically using Forward Time Centered Space (FTCS) approach. The numerical results have been used to study the relationships among different types of parameters such as buffer concentration, association rate, calcium permeability.
Abstract: Ultrastructure of duodenum mucosa of irradiated rat
was studied versus dose rate of irradiation following exposure to
gamma rays from 60-Cobalt source. The animals were whole body
irradiated at two dose rates (1 Gy.mn-1 and 1 Gy.h-1) and three total
doses (1, 2 or 4 Gy) for each dose rate. 24 or 48 h after irradiation,
their small intestine was removed and samples of duodenum were
processed for observations under a transmission electron microscopy.
Samples of duodenum mucosa of control rats were processed in the
same way. For the lower dose rate of 1 Gy.h-1, main lesions
characteristic of apoptosis were detected within irradiated enterocytes
at a total dose of 2 Gy and 24 h after exposure. Necrosis was noted in
the samples, 48 h after exposition. For the higher dose rate of 1
Gy.mn-1, fewer changes were detected at all total doses 24 or 48 h
irradiation. Thus, it was shown that the appearance of radiationinduced
alterations varies not only with increasing total dose and
post-irradiation time but especially with decreasing dose rate.
Abstract: In this study, direct numerical simulation for the bubble condensation in the subcooled boiling flow was performed. The main goal was to develop the CFD modeling for the bubble condensation and to evaluate the accuracy of the VOF model with the developed CFD modeling. CFD modeling for the bubble condensation was developed by modeling the source terms in the governing equations of VOF model using UDF. In the modeling, the amount of condensation was determined using the interfacial heat transfer coefficient obtained from the bubble velocity, liquid temperature and bubble diameter every time step. To evaluate the VOF model using the CFD modeling for the bubble condensation, CFD simulation results were compared with SNU experimental results such as bubble volume and shape, interfacial area, bubble diameter and bubble velocity. Simulation results predicted well the behavior of the actual condensing bubble. Therefore, it can be concluded that the VOF model using the CFD modeling for the bubble condensation will be a useful computational fluid dynamics tool for analyzing the behavior of the condensing bubble in a wide range of the subcooled boiling flow.
Abstract: Due to the legacy of apartheid segregation South Africa remains a divided society where most voters live in politically homogenous social environments. This paper argues that political discussion within one’s social context plays a primary role in shaping political attitudes and vote choice. Using data from the Comparative National Elections Project 2004 and 2009 South African post-election surveys, the paper explores the extent of social context partisan homogeneity in South Africa and finds that voters are not overly embedded in homogenous social contexts. It then demonstrates the consequences of partisan homogeneity on voting behavior. Homogenous social contexts tend to encourage stronger partisan loyalties and fewer defections in vote choice while voters in more heterogeneous contexts show less consistency in their attitudes and behaviour. Finally, the analysis shows how momentous sociopolitical events at the time of a particular election can change the social context, with important consequences for electoral outcomes.
Abstract: In the control theory one attempts to find a controller
that provides the best possible performance with respect to some
given measures of performance. There are many sorts of controllers
e.g. a typical PID controller, LQR controller, Fuzzy controller etc. In
the paper will be introduced polynomial controller with novel tuning
method which is based on the special pole placement encoding
scheme and optimization by Genetic Algorithms (GA). The examples
will show the performance of the novel designed polynomial
controller with comparison to common PID controller.
Abstract: Needs of an efficient information retrieval in recent
years in increased more then ever because of the frequent use of
digital information in our life. We see a lot of work in the area of
textual information but in multimedia information, we cannot find
much progress. In text based information, new technology of data
mining and data marts are now in working that were started from the
basic concept of database some where in 1960.
In image search and especially in image identification,
computerized system at very initial stages. Even in the area of image
search we cannot see much progress as in the case of text based
search techniques. One main reason for this is the wide spread roots
of image search where many area like artificial intelligence,
statistics, image processing, pattern recognition play their role. Even
human psychology and perception and cultural diversity also have
their share for the design of a good and efficient image recognition
and retrieval system.
A new object based search technique is presented in this paper
where object in the image are identified on the basis of their
geometrical shapes and other features like color and texture where
object-co-relation augments this search process.
To be more focused on objects identification, simple images are
selected for the work to reduce the role of segmentation in overall
process however same technique can also be applied for other
images.
Abstract: A design flow of multi-standard down-conversion
CMOS mixers for three modern standards: Global System Mobile,
Digital Enhanced Cordless Telephone and Universal Mobile
Telecommunication Systems is presented. Three active mixer-s
structures are studied. The first is based on the Gilbert cell which
gives a tolerable noise figure and linearity with a low conversion
gain. The second and third structures use the current bleeding and
charge injection techniques in order to increase the conversion gain.
An improvement of about 2 dB of the conversion gain is achieved
without a considerable degradation of the other characteristics. The
models used for noise figure, conversion gain and IIP3 used are
studied. This study describes the nature of trade-offs inherent in such
structures and gives insights that help in identifying which structure
is better for given conditions.
Abstract: Post-anthesis drought stress is the most important
problem affecting wheat production in dryland fields, specially in
Mediterranean regions. The main objective of this research was to
evaluate drought tolerance indices in dryland wheat genotypes under
post-anthesis drought stress. The research was including two different
experiments. In each experiment, twenty dryland bread wheat
genotypes were sown in a randomized complete blocks design
(RCBD) with three replications. One of experiments belonged to
rain-fed conditions (post-anthesis drought stress) and other
experiment was under non-stress conditions (with supplemental
irrigation). Different drought tolerance indices include Stress
Tolerance (Tol), Mean Productivity (MP), Geometric Mean
Productivity (GMP), Stress Susceptibility Index (SSI), Stress
Tolerance Index (STI), Harmonic Mean (HAM), Yield Index (YI)
and Yield Stability Index (YSI) were evaluate based on grain yield
under rain-fed (Ys) and supplemental irrigation (Yp) environments.
G10 and G12 were the most tolerant genotypes based on TOL and
SSI. But, based on MP, GMP, STI, HAM and YI indices, G1 and G2
were selected. STI, GMP and MP indices had high correlation with
grain yield under rain-fed and supplementary irrigation conditions
and were recognized as appropriate indices to identify genotypes with
high grain yield and low sensitivity to drought stress environments.
Abstract: For cognitive radio networks, there is a major
spectrum sensing problem, i.e. dynamic spectrum management. It is
an important issue to sense and identify the spectrum holes in
cognitive radio networks. The first-order derivative scheme is usually
used to detect the edge of the spectrum. In this paper, a novel
spectrum sensing technique for cognitive radio is presented. The
proposed algorithm offers efficient edge detection. Then, simulation
results show the performance of the first-order derivative scheme and
the proposed scheme and depict that the proposed scheme obtains
better performance than does the first-order derivative scheme.
Abstract: Thrombosis can be life threatening, necessitating therefore its instant treatment. Hydergine, a nootropic agent is used as a cognition enhancer in stroke patients but relatively little is known about its anti-thrombolytic effect. To investigate this aspect, in vivo and ex vivo experiments were designed and conducted. Three groups of rats were injected 1.5mg, 3.0mg and 4.5mg hydergine intraperitonealy with and without prior exposure to fresh plasma. Positive and negative controls were run in parallel. Animals were sacrificed after 1.5hrs and BT, CT, PT, INR, APTT, plasma calcium levels were estimated. For ex vivo analyses, each 1ml blood aspirated was exposed to 0.1mg, 0.2mg, 0.3mg dose of hydergine with parallel controls. Parameters analyzed were as above. Statistical analysis was through one-way ANOVA. Dunken-s and Tukey-s tests provided intra-group variance. BT, CT, PT, INR and APTT increased while calcium levels dropped significantly (P
Abstract: Polymeric microreactors have emerged as a new
generation of carriers that hold tremendous promise in the areas of
cancer therapy, controlled delivery of drugs, for removal of
pollutants etc. Present work reports a simple and convenient
methodology for synthesis of polystyrene and poly caprolactone
microreactors. An aqueous suspension of carboxylated (1μm)
polystyrene latex particles was mixed with toluene solution followed
by freezing with liquid nitrogen. Freezed particles were incubated at
-20°C and characterized for formation of voids on the surface of
polymer microspheres by Field Emission Scanning Electron
Microscope. The hollow particles were then overnight incubated at
40ºC with unfunctionalized quantum dots (QDs) in 5:1 ratio. QDs
Encapsulated polystyrene microcapsules were characterized by
fluorescence microscopy.
Likewise Poly ε-caprolactone microreactors were prepared by
micro-volcanic rupture of freeze dried microspheres synthesized
using emulsification of polymer with aqueous Poly vinyl alcohol and
freezed with liquid nitrogen. Microreactors were examined with Field
Emission Scanning Electron Microscope for size and morphology.
Current study is an attempt to create hollow polymer particles which
can be employed for microencapsulation of nanoparticles and drug
molecules.
Abstract: ZnO+Ga2O3 functionally graded thin films (FGTFs)
were examined for their potential use as Solar cell and organic light
emitting diodes (OLEDs). FGTF transparent conducting oxides (TCO)
were fabricated by combinatorial RF magnetron sputtering. The
composition gradient was controlled up to 10% by changing the
plasma power of the two sputter guns. A Ga2O3+ZnO graded region
was placed on the top layer of ZnO. The FGTFs showed up to 80%
transmittance. Their surface resistances were reduced to < 10% by
increasing the Ga2O3: pure ZnO ratio in the TCO. The FGTFs- work
functions could be controlled within a range of 0.18 eV. The
controlled work function is a very promising technology because it
reduces the contact resistance between the anode and Hall transport
layers of OLED and solar cell devices.
Abstract: There have been many games developing simulation
of soccer games. Many of these games have been designed with
highly realistic features to attract more users. Many have also
incorporated better artificial intelligent (AI) similar to that in a real
soccer game. One of the challenging issues in a soccer game is the
cooperation, coordination and negotiation among distributed agents
in a multi-agent system. This paper focuses on the incorporation of
multi-agent technique in a soccer game domain. The better the
cooperation of a multi-agent team, the more intelligent the game will
be. Thus, past studies were done on the robotic soccer game because
of the better multi-agent system implementation. From this study, a
better approach and technique of multi-agent behavior could be
select to improve the author-s 2D online soccer game.
Abstract: Implementing Information Technology/ Information
System (IT/IS) is critical for every industry as its potential benefits
have been to motivate many industries including the Malaysian
construction industry to invest in it. To successfully implement IT/IS
has become the major concern for every organisation. Identifying the
critical success factors (CSFs) has become the main agenda for
researchers, academicians and practitioners due to the wide number
of failures reported. This research paper seeks to identify the CSFs
that influence the successful implementation of IT/IS in construction
industry in Malaysia. Limited factors relating to people issue will be
highlighted here to showcase some as it becomes one of the major
contributing factors to the failure. Three (3) organisations have
participated in this study. Semi-structured interviews are employed as
they offer sufficient flexibility to ensure that all relevant factors are
covered. Several key issues contributing to successful
implementations of IT/IS are identified. The results of this study
reveal that top management support, communication, user
involvement, IT staff roles and responsibility, training/skills, leader/
IT Leader, organisation culture, knowledge/ experience, motivation,
awareness, focus and ambition, satisfaction, teamwork/ collaboration,
willingness to change, attitude, commitment, management style,
interest in IT, employee behaviour towards collaborative
environment, trust, interpersonal relationship, personal characteristic
and competencies are significantly associated with the successful
implementations of IT/IS. It is anticipated that this study will create
awareness and contribute to a better understanding amongst
construction industry players and will assist them to successfully
implement IT/IS.
Abstract: The effects of global warming on India vary from the
submergence of low-lying islands and coastal lands to the melting of
glaciers in the Indian Himalayas, threatening the volumetric flow rate
of many of the most important rivers of India and South Asia. In
India, such effects are projected to impact millions of lives. As a
result of ongoing climate change, the climate of India has become
increasingly volatile over the past several decades; this trend is
expected to continue.
Climate change is one of the most important global environmental
challenges, with implications for food production, water supply,
health, energy, etc. Addressing climate change requires a good
scientific understanding as well as coordinated action at national and
global level. The climate change issue is part of the larger challenge
of sustainable development. As a result, climate policies can be more
effective when consistently embedded within broader strategies
designed to make national and regional development paths more
sustainable. The impact of climate variability and change, climate
policy responses, and associated socio-economic development will
affect the ability of countries to achieve sustainable development
goals.
A very well calibrated Soil and Water Assessment Tool (R2 =
0.9968, NSE = 0.91) was exercised over the Khatra sub basin of the
Kangsabati River watershed in Bankura district of West Bengal,
India, in order to evaluate projected parameters for agricultural
activities. Evapotranspiration, Transmission Losses, Potential
Evapotranspiration and Lateral Flow to reach are evaluated from the
years 2041-2050 in order to generate a picture for sustainable
development of the river basin and its inhabitants.
India has a significant stake in scientific advancement as well as
an international understanding to promote mitigation and adaptation.
This requires improved scientific understanding, capacity building,
networking and broad consultation processes. This paper is a
commitment towards the planning, management and development of
the water resources of the Kangsabati River by presenting detailed
future scenarios of the Kangsabati river basin, Khatra sub basin, over
the mentioned time period.
India-s economy and societal infrastructures are finely tuned to the
remarkable stability of the Indian monsoon, with the consequence
that vulnerability to small changes in monsoon rainfall is very high.
In 2002 the monsoon rains failed during July, causing profound loss
of agricultural production with a drop of over 3% in India-s GDP.
Neither the prolonged break in the monsoon nor the seasonal rainfall
deficit was predicted. While the general features of monsoon
variability and change are fairly well-documented, the causal
mechanisms and the role of regional ecosystems in modulating the
changes are still not clear. Current climate models are very poor at
modelling the Asian monsoon: this is a challenging and critical
region where the ocean, atmosphere, land surface and mountains all
interact. The impact of climate change on regional ecosystems is
likewise unknown. The potential for the monsoon to become more
volatile has major implications for India itself and for economies
worldwide. Knowledge of future variability of the monsoon system,
particularly in the context of global climate change, is of great
concern for regional water and food security.
The major findings of this paper were that of all the chosen
projected parameters, transmission losses, soil water content,
potential evapotranspiration, evapotranspiration and lateral flow to
reach, display an increasing trend over the time period of years 2041-
2050.
Abstract: We deal with the numerical solution of time-dependent convection-diffusion-reaction equations. We combine the local projection stabilization method for the space discretization with two different time discretization schemes: the continuous Galerkin-Petrov (cGP) method and the discontinuous Galerkin (dG) method of polynomial of degree k. We establish the optimal error estimates and present numerical results which shows that the cGP(k) and dG(k)- methods are accurate of order k +1, respectively, in the whole time interval. Moreover, the cGP(k)-method is superconvergent of order 2k and dG(k)-method is of order 2k +1 at the discrete time points. Furthermore, the dependence of the results on the choice of the stabilization parameter are discussed and compared.
Abstract: In this paper methodology to exploit creeping wave
for body area network BAN communication reliability are described.
Creeping wave propagation effects are visualized & analyzed.
During this work Dipole, IA antennas various antennas were
redesigned using existing designs and their propagation
characteristics were verified for optimum performance when used on
BANs. These antennas were then applied on body shapes-including
rectangular, spherical and cylindrical so that all the effects of actual
human body can be taken nearly into account. Parametric simulation
scheme was devised so that on Body channel characterization can be
visualized at front, curved and back region. In the next phase
multiple inputs multiple output MIMO scheme was introduced where
virtual antennas were used in order to diminish the effects of
antennas on the propagation of waves. Results were, extracted and
analyzed at different heights. Finally based on comparative
measurement and analysis it was concluded that on body propagation
can be exploited to gain spatial diversity.
Abstract: This paper explores the use of project work in a
content-based instruction in a Rajabhat University, a teacher college,
where student teachers are instructed to perform teaching roles
mainly in basic education level. Its aim is to link theory to practice,
and to help language teachers maximize the full potential of project
work for genuine communication and give real meaning to writing
activity. Two research questions are formulated to guide this study:
a) What is the academic achievement of the students- writing skill
against the 70% attainment target after the use of project to enhance
the skill? and b) To what degree is the development of the students-
writing skills during the course of project to enhance the skill? The
sample of the study comprised of 38 fourth-year English major
students. The data was collected by means of achievement test,
student writing works, and project diary. The scores in the summative
achievement test were analyzed by mean score, standard deviation,
and t-test. Project diary serves as students- record of the language
acquired during the project. List of structures and vocabulary noted in
the diary has shown students- ability to attend to, recognize, and
focus on meaningful patterns of language forms.
Abstract: The product development process (PDP) in the
Technology group plays a very important role in the launch of any
product. While a manufacturing process encourages the use of certain
measures to reduce health, safety and environmental (HSE) risks on
the shop floor, the PDP concentrates on the use of Geometric
Dimensioning and Tolerancing (GD&T) to develop a flawless design.
Furthermore, PDP distributes and coordinates activities between
different departments such as marketing, purchasing, and
manufacturing. However, it is seldom realized that PDP makes a
significant contribution to developing a product that reduces HSE
risks by encouraging the Technology group to use effective GD&T.
The GD&T is a precise communication tool that uses a set of
symbols, rules, and definitions to mathematically define parts to be
manufactured. It is a quality assurance method widely used in the oil
and gas sector. Traditionally it is used to ensure the
interchangeability of a part without affecting its form, fit, and
function. Parts that do not meet these requirements are rejected
during quality audits.
This paper discusses how the Technology group integrates this
quality assurance tool into the PDP and how the tool plays a major
role in helping the HSE department in its goal towards eliminating
HSE incidents. The PDP involves a thorough risk assessment and
establishes a method to address those risks during the design stage.
An illustration shows how GD&T helped reduce safety risks by
ergonomically improving assembling operations. A brief discussion
explains how tolerances provided on a part help prevent finger injury.
This tool has equipped Technology to produce fixtures, which are
used daily in operations as well as manufacturing. By applying
GD&T to create good fits, HSE risks are mitigated for operating
personnel. Both customers and service providers benefit from
reduced safety risks.
Abstract: Nigella sativa L. is an aromatic plant belonging to the
family Ranunculaceae. It has been used traditionally, especially in the
middle East and India, for the treatment of asthma, cough, bronchitis,
headache, rheumatism, fever, influenza and eczema. Several
biological activities have been reported in Nigella sativa seeds,
including antioxidant. In this context we tried to estimate the
antioxidant activity of various extracts prepared from Nigella sativa
seeds, methanolic extract (ME), chloroformic extract (CE), hexanic
extract (HE : fixed oil), ethyl acetate extract (EAE) water extract
(WE). The Folin-Ciocalteu assay showed that CE and EAE contained
high level of phenolic compounds 81.31 and 72.43μg GAE/mg of
extract respectively. Similarly, the CE and EAE exhibited the highest
DPPH radical scavenging activity, with IC50 values of 106.56μg/ml
and 121.62μg/ml respectively. In addition, CE and HE showed the
most scavenging activity against superoxide radical generated in the
PMS-NADH-NBT system with respective IC50 values of 361.86
μg/ml and 371.80 μg/ml, which is comparable to the activity of the
standard antioxidant BHT (344.59 μg/ml). Ferrous ion chelating
capacity assay showed that WE, EAE and ME are the most active
with 40.57, 39.70 and 22.02 mg EDTA-E/g of extract. The inhibition
of linoleic acid/ß-carotene coupled oxidation was estimated by ßcarotene
bleaching assay, this showed a highest relative antioxidant
activity with CE and EAE (69.82% of inhibition). The antioxidant
activities of the methanolic extract and the fixed oil are confirmed by
an in vivo assay in mice, the daily oral administration of methanolic
extract (500 and 800 mg/kg/day) and fixed oil (2 and 4 ml/kg/day)
during 21 days, resulted in a significant enhancement of the blood
total antioxidant capacity (measured by KRL test) and the plasmatic
antioxidant capacity towards DPPH radical.