Abstract: Lean production (or lean management respectively)
gained popularity in several waves. The last three decades have been
filled with numerous attempts to apply these concepts in companies.
However, this has only been partially successful. The roots of lean
production can be traced back to Toyota-s just-in-time production.
This concept, which according to Womack-s, Jones- and Roos-
research at MIT was employed by Japanese car manufacturers,
became popular under its international names “lean production",
“lean-manufacturing" and was termed “Schlanke Produktion" in
Germany. This contribution shows a review about lean production in
Germany over the last thirty years: development, trial & error and
implementation as well.
Abstract: Lean manufacturing is a production philosophy made
popular by Toyota Motor Corporation (TMC). It is globally known as
the Toyota Production System (TPS) and has the ultimate aim of
reducing cost by thoroughly eliminating wastes or muda. TPS
embraces the Just-in-time (JIT) manufacturing; achieving cost
reduction through lead time reduction. JIT manufacturing can be
achieved by implementing Pull system in the production.
Furthermore, TPS aims to improve productivity and creating
continuous flow in the production by arranging the machines and
processes in cellular configurations. This is called as Cellular
Manufacturing Systems (CMS). This paper studies on integrating the
CMS with the Pull system to establish a Big Island-Pull system
production for High Mix Low Volume (HMLV) products in an
automotive component industry. The paper will use the build-in JIT
system steps adapted from TMC to create the Pull system production
and also create a shojinka line which, according to takt time, has the
flexibility to adapt to demand changes simply by adding and taking
out manpower. This will lead to optimization in production.
Abstract: Mechanical and water transport properties of high
performance concrete (HPC) containing natural zeolite as partial
replacement of Portland cement are studied. Experimental results
show that in the investigated mixes the use of natural zeolite leads to
an increase of porosity, decrease of compressive strength and
increase of moisture diffusivity and water vapor diffusion coefficient,
as compared with the reference HPC. However, for the replacement
level up to 20% of the mass of Portland cement the concretes still
maintain their high performance character and exhibit acceptable
water transport properties. Therefore, natural zeolite can be
considered an environmental friendly binder with a potential to
replace a part of Portland cement in concrete in building industry.
Abstract: Recent research has shown that milk proteins can
yield bioactive peptides with opioid, mineral binding,
cytomodulatory, antihypertensive, immunostimulating, antimicrobial
and antioxidative activity in the human body. Bioactive peptides are
encrypted in milk proteins and are only released by enzymatic
hydrolysis in vivo during gastrointestinal digestion, food processing
or by microbial enzymes in fermented products. At present
significant research is being undertaken on the health effects of
bioactive peptides. A variety of naturally formed bioactive peptides
have been found in fermented dairy products, such as yoghurt, sour
milk and cheese. In particular, antihypertensive peptides have been
identified in fermented milks, whey and ripened cheese. Some of
these peptides have been commercialized in the form of fermented
milks. Bioactive peptides have the potential to be used in the
formulation of health-enhancing nutraceuticals, and as potent drugs
with well defined pharmacological effects.
Abstract: Tehran, one of the heavily-populated capitals, is
severely suffering from increasing air pollution. To show a
documented trend of such pollutants during last years, plane tree
species (Platanus orientalis) were suited to be studied as indicators,
for the species have been planted throughout the city many years
ago. Two areas (Saadatabad and Narmak districts) allotting different
contents of crowed and highly-traffic routs but the same ecological
characteristics were selected. Twelve sample individuals were cored
twice perpendicularly in each area. Tree-rings of each core were
measured by a binocular microscope and separated annually for the
last 25 years. Two heavy metals including Cd and Pb accompanied
by a mineral element (Ca) were analyzed using Hatch method. Treerings
analysis of the two areas showed different groups in term of
physiologically ability as the growths were plunged during the last
10 years in Saadatabad district and showed a slight decrease in the
same period for another studying area. In direct contrast to
decreasing growth trend in Saadatabad, all three mentioned elements
increased sharply during last 25 years in the same area. When it came
to Narmak district, the trend was completely different with
Saadatabad. There were some fluctuations in absorbing trace
elements like tree-rings widths were, yet calcium showed an upward
trend all the last 25 years. The results of the study proved the
possibility of using tree species of each region to monitor its air
pollution trends of the past, hence to depict a pollution assessment of
a populated city for last years and then to make appropriate decisions
for the future as it is well-known what the trend is. On the other
hand, risen values of calcium (as the stress-indicator element)
accompanied by increased trace elements suggests non-sustainable
state of the trees.
Abstract: Massive use of places with strong tourist attraction
with the consequent possibility of losing place-identity produces
harmful effects on cities and their users. In order to mitigate this risk,
areas close to such places can be identified so as to widen the
visitor-s range of action and offer alternative activities integrated
with the main site. The cultural places and appropriate activities can
be identified using a method of analysis and design able to trace the
identity of the places, their characteristics and potential, and to
provide a sustainable improvement. The aim of this work is to
propose PlaceMaker as a method of urban analysis and design which
both detects elements that do not feature in traditional mapping and
which constitute the contemporary identity of the places, and
identifies appropriate project interventions. Two final complex maps
– the first of analysis and the second of design – respectively
represent the identity of places and project interventions. In order to
illustrate the method-s potential; the results of the experimentation
carried out in the Trevi-Pantheon route in Rome and the appropriate
interventions to decongest the area are illustrated.
Abstract: This paper introduces an isolated and unique ancient language Burushaski, spoken in Hunza, Nagar, Yasin and parts of Gilgit in the Northern Areas of Pakistan. It explains the working mechanism of Multi Language Text Editor for Urdu and Burushaski. It is developed under the use of ISO/IEC 10646 Unicode standards for Urdu and Burushaski open-type fonts. It gives an ample opportunity to this regional ancient language to have a modern Information technology for its promotion and preservation. The main objective of this research paper is to help preserve the heritage of such rare languages and give smart way of automation. It also facilitates to those who are interested in undertaking research on Burushaski or keen to trace fonatic relationship between the national Urdu language and Burushaski. Since this editor covers both Burushaski and Urdu so it can play an important role to introduce Burusho linguistic culture to the world at large. Precisely, as a result of this research paper, Burushaski publication through IT means would be possible.
Abstract: Functional gastrointestinal disorders affect millions of people spread all age regardless of race and sex. There are, however, rare diagnostic methods for the functional gastrointestinal disorders because functional disorders show no evidence of organic and physical causes. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. Aim of this study is, therefore, to develop a diagnostic system for the functional gastrointestinal disorders based on ultrasound technique, which can quantify the characteristic above related to the rigidity of the gastrointestinal tract well. Ultrasound system was designed. The system consisted of transmitter, ultrasonic transducer, receiver, TGC, and CPLD, and verified via a phantom test. For the phantom test, ten soft-tissue specimens were harvested from porcine. Five of them were then treated chemically to mimic a rigid condition of gastrointestinal tract well, which was induced by functional gastrointestinal disorders. Additionally, the specimens were tested mechanically to identify if the mimic was reasonable. The customized ultrasound system was finally verified through application to human subjects with/without functional gastrointestinal disorders (Normal and Patient Groups). It was identified from the mechanical test that the chemically treated specimens were more rigid than normal specimen. This finding was favorably compared with the result obtained from the phantom test. The phantom test also showed that ultrasound system well described the specimen geometric characteristics and detected an alteration in the specimens. The maximum amplitude of the ultrasonic reflective signal in the rigid specimens (0.2±0.1Vp-p) at the interface between the fat and muscle layers was explicitly higher than that in the normal specimens (0.1±0.0Vp-p). Clinical tests using our customized ultrasound system for human subject showed that the maximum amplitudes of the ultrasonic reflective signals near to the gastrointestinal tract well for the patient group (2.6±0.3Vp-p) were generally higher than those in normal group (0.1±0.2Vp-p). Here, maximum reflective signals was appeared at 20mm depth approximately from abdominal skin for all human subjects, corresponding to the location of the boundary layer close to gastrointestinal tract well. These results suggest that newly designed diagnostic system based on ultrasound technique may diagnose enough the functional gastrointestinal disorders.
Abstract: Nonlinear response behaviour of a cracked RC beam under harmonic excitation is analysed to investigate various instability phenomena like, bifurcation, jump phenomena etc. The nonlinearity of the system arises due to opening and closing of the cracks in the RC beam and is modelled as a cubic polynomial. In order to trace different branches at the bifurcation point on the response curve (amplitude versus frequency of excitation plot), an arc length continuation technique along with the incremental harmonic balance (IHBC) method is employed. The stability of the solution is investigated by the Floquet theory using Hsu-s scheme. The periodic solutions obtained by the IHBC method are compared with these obtained by the numerical integration of the equation of motion. Characteristics of solutions fold bifurcation, jump phenomena and from stable to unstable zones are identified.
Abstract: Ceramics comprise the largest proportion of Korea-s cultural heritage currently preserved (Cited from “The Beauty of Old Ceramics of Korea" written by Yoon Yong-iee). Thus, this researcher conducted this investigation in an attempt to gain insight into Korea-s past culture and the lost period of the colonial period and the Korean War by looking into the ceramics. Korea, China and Japan are part of the similar cultural bloc within the East Asian region. Their porcelains manifest distinctive characteristics by each nation along with similarities. Thus, this research seeks to find the distinctive characteristics of the Korean porcelain by conducting comparative analysis of the similarities and distinctive characteristics. These distinctive characteristics are manifested effectively in the colors of the porcelains following the materials that can be obtained in Korea, China and Japan and production method. Likewise, this research seeks to identify the characteristics of the Korean porcelains- colors based on the comparative analysis of the porcelain colors. The reasons that porcelains were selected were because they are the most well preserved cultural remains in Korea and since they have both similarities and distinctive characteristics due to the cultural interchanges among Korea, China and Japan, which facilitates comparative study. The research targets include Korea, China and Japan-s porcelains. By comparing the colors of the porcelains from Korea, China and Japan that have their distinctive characteristics, this research seeks to identify Korea-specific porcelain colors. These colors derive from the materials that can be obtained only in Korea, and they are affected by the ideologies that governed at the time. This research is meaningful in the sense that this identifies the colors that embraces the Korean culture and provides important data by leveraging the study of the characteristics of the Korea-specific porcelains.
Abstract: In this study, lipase production has been investigated
using submerge fermentation by Aspergillus niger in Kilka fish oil as
main substrate. The Taguchi method with an L9 orthogonal array
design was used to investigate the effect of parameters and their
levels on lipase productivity. The optimum conditions for Kilka fish
oil concentration, incubation temperature and pH were obtained 3
gr./ml 35°C and 7, respectively. The amount of lipase activity in
optimum condition was obtained 4.59IU/ml. By comparing this
amount with the amount of productivity in the olive oil medium
based on the cost of each medium, it was that using Kilka fish oil is
84% economical. Therefore Kilka fish oil can be used as an
economical and suitable substrate in the lipase production and
industrial usages.
Abstract: Trace element speciation of an integrated soil
amendment matrix was studied with a modified BCR sequential
extraction procedure. The analysis included pseudo-total
concentration determinations according to USEPA 3051A and
relevant physicochemical properties by standardized methods. Based
on the results, the soil amendment matrix possessed neutralization
capacity comparable to commercial fertilizers. Additionally, the
pseudo-total concentrations of all trace elements included in the
Finnish regulation for agricultural fertilizers were lower than the
respective statutory limit values. According to chemical speciation,
the lability of trace elements increased in the following order: Hg <
Cr < Co < Cu < As < Zn < Ni < Pb < Cd < V < Mo < Ba. The
validity of the BCR approach as a tool for chemical speciation was
confirmed by the additional acid digestion phase. Recovery of trace
elements during the procedure assured the validity of the approach
and indicated good quality of the analytical work.
Abstract: Hyperglycemia-mediated accumulation of advanced glycation end-products (AGEs) play a pivotal role in the development of diabetic complications by inducing inflammation. In the present study, we evaluated the possible effects of water/ethanol (1/1, v/v) extracts (WEE) and its fractions from Canarium album Raeusch. (Chinese olive) which is a fruit used on AGEs-stimulated oxidative stress and inflammation in monocytes and vascular endothelial cells. Co-incubation of EA.hy926 endothelial cells with WEE and its fractions for 24h resulted in a significant decrease of monocyte–endothelial cell adhesion, the expression of ICAM-1, generation of intracellular ROS and depletion of GSH induced by AGEs. Chinese olive fruit extracts also reduced the expression of pro-inflammatory mediates, such as TNF-α, IL-1β and IL-6 in THP-1 cells. These findings suggested that Chinese olive fruit was able to protect vascular endothelium from dysfunction induced by AGEs.
Abstract: Tracing and locating the geographical location of users (Geolocation) is used extensively in todays Internet. Whenever we, e.g., request a page from google we are - unless there was a specific configuration made - automatically forwarded to the page with the relevant language and amongst others, dependent on our location identified, specific commercials are presented. Especially within the area of Network Security, Geolocation has a significant impact. Because of the way the Internet works, attacks can be executed from almost everywhere. Therefore, for an attribution, knowledge of the origination of an attack - and thus Geolocation - is mandatory in order to be able to trace back an attacker. In addition, Geolocation can also be used very successfully to increase the security of a network during operation (i.e. before an intrusion actually has taken place). Similar to greylisting in emails, Geolocation allows to (i) correlate attacks detected with new connections and (ii) as a consequence to classify traffic a priori as more suspicious (thus particularly allowing to inspect this traffic in more detail). Although numerous techniques for Geolocation are existing, each strategy is subject to certain restrictions. Following the ideas of Endo et al., this publication tries to overcome these shortcomings with a combined solution of different methods to allow improved and optimized Geolocation. Thus, we present our architecture for improved Geolocation, by designing a new algorithm, which combines several Geolocation techniques to increase the accuracy.
Abstract: Modeling and simulation of biochemical reactions is of great interest in the context of system biology. The central dogma of this re-emerging area states that it is system dynamics and organizing principles of complex biological phenomena that give rise to functioning and function of cells. Cell functions, such as growth, division, differentiation and apoptosis are temporal processes, that can be understood if they are treated as dynamic systems. System biology focuses on an understanding of functional activity from a system-wide perspective and, consequently, it is defined by two hey questions: (i) how do the components within a cell interact, so as to bring about its structure and functioning? (ii) How do cells interact, so as to develop and maintain higher levels of organization and functions? In recent years, wet-lab biologists embraced mathematical modeling and simulation as two essential means toward answering the above questions. The credo of dynamics system theory is that the behavior of a biological system is given by the temporal evolution of its state. Our understanding of the time behavior of a biological system can be measured by the extent to which a simulation mimics the real behavior of that system. Deviations of a simulation indicate either limitations or errors in our knowledge. The aim of this paper is to summarize and review the main conceptual frameworks in which models of biochemical networks can be developed. In particular, we review the stochastic molecular modelling approaches, by reporting the principal conceptualizations suggested by A. A. Markov, P. Langevin, A. Fokker, M. Planck, D. T. Gillespie, N. G. van Kampfen, and recently by D. Wilkinson, O. Wolkenhauer, P. S. Jöberg and by the author.
Abstract: Nowaday-s, many organizations use systems that
support business process as a whole or partially. However, in some
application domains, like software development and health care
processes, a normative Process Aware System (PAS) is not suitable,
because a flexible support is needed to respond rapidly to new
process models. On the other hand, a flexible Process Aware System
may be vulnerable to undesirable and fraudulent executions, which
imposes a tradeoff between flexibility and security. In order to make
this tradeoff available, a genetic-based anomaly detection model for
logs of Process Aware Systems is presented in this paper. The
detection of an anomalous trace is based on discovering an
appropriate process model by using genetic process mining and
detecting traces that do not fit the appropriate model as anomalous
trace; therefore, when used in PAS, this model is an automated
solution that can support coexistence of flexibility and security.
Abstract: This paper explores the changing trend in citizenship
norms among young citizens from various ethnic groups in Malaysia
and the extent to which it influences the participation of young
citizens in political and civil issues. Embedded in democratic
constitutions are the rights and freedoms that accompany citizenship,
and these rights and freedoms include participation. Participation in
democracies should go beyond voting; it should include taking part in
the governance process. The political process is not at risk even
though politics does not work as it did in the past. A national sample
of 1697 respondents between the ages of 21 and 40 years were
interviewed in January 2011. The findings show that respondents
embrace an engaged-citizenship norm more than they do the
traditional duty-citizen norm. Among the ethnic groups, the Chinese
show lower means in both citizenship norms compared with other
ethnic groups, namely, the Malays and the Indians. The duty-citizen
norm correlates higher with political participation than with civic
participation. On the other hand, the engaged-citizen norm correlates
higher with civic participation than with political participation.
Abstract: This paper is an overview of the structure of Radio
Frequency Identification (RFID) systems and radio frequency bands
used by RFID technology. It also presents a solution based on the
application of RFID for brand authentication, traceability and
tracking, by implementing a production management system and
extending its use to traders.
Abstract: Toxoplasma gondii is an intracellular parasite capable
of infecting all nucleated cells in a diverse array of species.
Toxoplasma plaque assay have been described using Bacto Agar.
Because of its experimental advantages carboxymethyl cellulose
overlay, medium viscosity was choosing and the aim of this work
was to develop alternative method for formation of T. gondii plaques.
Tachyzoites were inoculated onto monolayers of Vero cells and
cultured at 37° C under 5 % CO2. The cultures were followed up by
microscopy inspection. Small plaques were visible by naphtol blue
stain 4 days after infection. Larger plaques could be observed by day
10 of culture. The carboxymethyl cellulose is a cheap reagent and the
methodology is easier, faster than assays under agar overlay. This is
the first description of the carboxymethyl cellulose overlay use for
obtaining the formation of T. gondii plaques and may be useful in
consequent obtaining tachyzoites for detailed studies.
Abstract: This manuscript presents a fast blind signature scheme
with extremely low computation for users. Only several modular additions
and multiplications are required for a user to obtain and verify
a signature in the proposed scheme. Comparing with the existing
ones in the literature, the scheme greatly reduces the computations
for users.