Abstract: We have developed a database for membrane protein functions, which has more than 3000 experimental data on functionally important amino acid residues in membrane proteins along with sequence, structure and literature information. Further, we have proposed different methods for identifying membrane proteins based on their functions: (i) discrimination of membrane transport proteins from other globular and membrane proteins and classifying them into channels/pores, electrochemical and active transporters, and (ii) β-signal for the insertion of mitochondrial β-barrel outer membrane proteins and potential targets. Our method showed an accuracy of 82% in discriminating transport proteins and 68% to classify them into three different transporters. In addition, we have identified a motif for targeting β-signal and potential candidates for mitochondrial β-barrel membrane proteins. Our methods can be used as effective tools for genome-wide annotations.
Abstract: Power loss reduction is one of the main targets in power industry and so in this paper, the problem of finding the optimal configuration of a radial distribution system for loss reduction is considered. Optimal reconfiguration involves the selection of the best set of branches to be opened ,one each from each loop, for reducing resistive line losses , and reliving overloads on feeders by shifting the load to adjacent feeders. However ,since there are many candidate switching combinations in the system ,the feeder reconfiguration is a complicated problem. In this paper a new approach is proposed based on a simple optimum loss calculation by determining optimal trees of the given network. From graph theory a distribution network can be represented with a graph that consists a set of nodes and branches. In fact this problem can be viewed as a problem of determining an optimal tree of the graph which simultaneously ensure radial structure of each candidate topology .In this method the refined genetic algorithm is also set up and some improvements of algorithm are made on chromosome coding. In this paper an implementation of the algorithm presented by [7] is applied by modifying in load flow program and a comparison of this method with the proposed method is employed. In [7] an algorithm is proposed that the choice of the switches to be opened is based on simple heuristic rules. This algorithm reduce the number of load flow runs and also reduce the switching combinations to a fewer number and gives the optimum solution. To demonstrate the validity of these methods computer simulations with PSAT and MATLAB programs are carried out on 33-bus test system. The results show that the performance of the proposed method is better than [7] method and also other methods.
Abstract: Demolitions of buildings have created a lot of waste
and one of it is clay bricks. The waste clay bricks were ground to
roughly cement fineness and used to partially replaced cement at
10%, 20% and 30% with w/b ratio of 0.6 and tested at 7, 28, 60, 90
and 120 days. The result shows that the compressive strength of GCB
concrete increases over age however, decreases as the level of
replacements increases. It was also found that 10% replacement of
GCB gave the highest compressive strength, however for optimum
replacement, 30% was chosen as it still attained strength of grade 30
concrete. In terms of durability performances, results show that GCB
replacement up to 30% was found to be efficient in reducing water
absorption as well as water permeability. These studies show that
GCB has the potential to be used as partial cement replacement in
making concrete.
Abstract: Aloe vera has been used worldwide both for
pharmaceutical, food, and cosmetic industries due to the plethora of
biological activities of some of its metabolites. The aim of this study
was to evaluate the antifungal and antioxidant activities of the leaf
extract. The antifungal activity was determined by the agar-well
diffusion method against plant and human fungal pathogens. The
methanol and ethanol portions of the extracts studied were more
bioactive than ethyl acetate portion. It was also observed that the
activity was more pronounced on plant pathogen than human
pathogen except Candida albicans. This is an indication that the
extract has the potential to treat plant fungal infections. The Aloe
extract showed the significant antioxidant activity by the DPPH
radical scavenging method. Therefore, the Aloe extract provided as
natural antioxidant has been used in health foods for medical and
preservative purposes.
Abstract: Catalytic converters are used for minimizing the release of pollutants to the atmosphere. It is during the warm-up period that hydrocarbons are seen to be released in appreciable quantities from these converters. In this paper the conversion of a fast oxidizing hydrocarbon propylene is analysed using two numerical methods. The quasi steady state method assumes the accumulation terms to be negligible in the gas phase mass and energy balance equations, however this term is present in the solid phase energy balance. The unsteady state model accounts for the accumulation term to be present in the gas phase mass and energy balance and in the solid phase energy balance. The results derived from the two models for gas concentration, gas temperature and solid temperature are compared.
Abstract: Experimental investigations were carried out in the
Manchester Tidal flow Facility (MTF) to study the flow patterns in
the region around and adjacent to a hypothetical headland in tidal
(oscillatory) ambient flow. The Planar laser-induced fluorescence
(PLIF) technique was used for visualization, with fluorescent dye
released at specific points around the headland perimeter and in its
adjacent recirculation zone. The flow patterns can be generalized into
the acceleration, stable flow and deceleration stages for each halfcycle,
with small variations according to location, which are more
distinct for low Keulegan-Carpenter number (KC) cases. Flow
patterns in the mixing region are unstable and complex, especially in
the recirculation zone. The flow patterns are in agreement with
previous visualizations, and support previous results in steady
ambient flow. It is suggested that the headland lee could be a viable
location for siting of pollutant outfalls.
Abstract: Fungal infections are becoming more common and the
range of susceptible individuals has expanded. While Candida
albicans remains the most common infective species, other Candida
spp. are becoming increasingly significant. In a range of large-scale
studies of candidaemia between 1999 and 2006, about 52% of 9717
cases involved C. albicans, about 30% involved either C. glabrata or
C. parapsilosis and less than 15% involved C. tropicalis, C. krusei or
C. guilliermondii. However, the probability of mortality within 30
days of infection with a particular species was at least 40% for C.
tropicalis, C. albicans, C. glabrata and C. krusei and only 22% for
C. parapsilopsis. Clinical isolates of Candida spp. grew at rates
ranging from 1.65 h-1 to 4.9 h-1. Three species (C. krusei, C. albicans
and C. glabrata) had relatively high growth rates (μm > 4 h-1), C.
tropicalis and C. dubliniensis grew moderately quickly (Ôëê 3 h-1) and
C. parapsilosis and C. guilliermondii grew slowly (< 2 h-1). Based
on these data, the log of the odds of mortality within 30 days of
diagnosis was linearly related to μm. From this the underlying
probability of mortality is 0.13 (95% CI: 0.10-0.17) and it increases
by about 0.09 ± 0.02 for each unit increase in μm. Given that the
overall crude mortality is about 0.36, the growth of Candida spp.
approximately doubles the rate, consistent with the results of larger
case-matched studies of candidaemia.
Abstract: This research deals with techno economic analysis to select the most economic desalination method for Asalouyeh combined cycle power plant . Due to lack of fresh water, desalination of sea water is necessary to provide required DM water of Power Plant. The most common desalination methods are RO, MSF, MED, and MED–TVC. In this research, methods of RO, MED, and MED– TVC have been compared. Simulation results show that recovery of heat of exhaust gas of main stack is optimum case for providing DM water required for injected steam of MED desalination. This subject is very important because of improving thermal efficiency of power plant using extra heat recovery. Also, it has been shown that by adding 3 rows of finned tube to de-aerator evaporator, which is very simple and low cost, required steam for generating 5200 m3/day of desalinated water is obtainable.
Abstract: Nowadays, where most of the leading economies are
service oriented and e-business is being widely used for their
management, supply chain management has become one of the most
studied and practiced fields. Quality has an important role on today-s
business processes, so it is important to understand the impact of IT
service quality on the performance of supply chains. This paper will
start by analyzing the Supply Chain Operations Reference (SCOR)
model and each of its five activities: Plan, Source, Make, Delivery,
and Return. This article proposes a framework for analyzing Effect of
IT Service Quality on Supply Chain Performance. Using the
proposed framework, hypotheses are framed for the direct effect of IT
service quality on Supply Chain Performance and its indirect effect
through effective Supply Chain Management. The framework will be
validated empirically based on the surveys of executives of various
organizations and statistical analyses of the data collected.
Abstract: In a product development process, understanding the functional behavior of the system, the role of components in achieving functions and failure modes if components/subsystem fails its required function will help develop appropriate design validation and verification program for reliability assessment. The integration of these three issues will help design and reliability engineers in identifying weak spots in design and planning future actions and testing program. This case study demonstrate the advantage of unascertained theory described in the subjective cognition uncertainty, and then applies blind number (BN) theory in describing the uncertainty of the mechanical system failure process and the same time used the same theory in bringing out another mechanical reliability system model. The practical calculations shows the BN Model embodied the characters of simply, small account of calculation but betterforecasting capability, which had the value of macroscopic discussion to some extent.
Abstract: In this paper, we investigate the study of techniques
for scheduling users for resource allocation in the case of multiple
input and multiple output (MIMO) packet transmission systems. In
these systems, transmit antennas are assigned to one user or
dynamically to different users using spatial multiplexing. The
allocation of all transmit antennas to one user cannot take full
advantages of multi-user diversity. Therefore, we developed the case
when resources are allocated dynamically. At each time slot users
have to feed back their channel information on an uplink feedback
channel. Channel information considered available in the schedulers
is the zero forcing (ZF) post detection signal to interference plus
noise ratio. Our analysis study concerns the round robin and the
opportunistic schemes.
In this paper, we present an overview and a complete capacity
analysis of these schemes. The main results in our study are to give
an analytical form of system capacity using the ZF receiver at the
user terminal. Simulations have been carried out to validate all
proposed analytical solutions and to compare the performance of
these schemes.
Abstract: In this paper a three dimensional thermal model of
high breaking capacity fuse with unequal fuse links is proposed for
both steady-state or transient conditions. The influence of ambient
temperature and electric current on the temperature distribution
inside the fuse, has been investigated. A thermal analysis of the
unbalanced distribution of the electric current through the fuse
elements and their influence on fuse link temperature rise, has been
performed. To validate the three dimensional thermal model, some
experimental tests have been done. There is a good correlation
between experimental and simulation results.
Abstract: The current education system in India is adept in
equipping and assessing the scholastic development of children.
However, there is an immediate need to strengthen co-scholastic
areas like life-skills, values and attitudes to equip students to face real
life challenges. Audio-visual technology and their respective media
can make a significant contribution to a value based learning
curriculum. Thus, co-scholastic skills need to be effectively nurtured
by a medium that is entertaining and impactful. Films in general have
a tremendous impact in our society. Films with a positive message
make a formidable learning experience that can influence and inspire
generations of learners. Leveraging on this powerful medium,
EduMedia India Pvt. Ltd. has introduced School Cinema a well
researched film-based learning module supported by a fun and
exciting workbook, designed to introduce and reaffirm life-skills and
values to children, thereby having a positive influence on their
attitudes.
Abstract: This study examines the issue of recommendation
sources from the perspectives of gender and consumers- perceived
risk, and validates a model for the antecedents of consumer online
purchases. The method of obtaining quantitative data was that of the
instrument of a survey questionnaire. Data were collected via
questionnaires from 396 undergraduate students aged 18-24, and a
multiple regression analysis was conducted to identify causal
relationships. Empirical findings established the link between
recommendation sources (word-of-mouth, advertising, and
recommendation systems) and the likelihood of making online
purchases and demonstrated the role of gender and perceived risk as
moderators in this context. The results showed that the effects of
word-of-mouth on online purchase intentions were stronger than those
of advertising and recommendation systems. In addition, female
consumers have less experience with online purchases, so they may be
more likely than males to refer to recommendations during the
decision-making process. The findings of the study will help
marketers to address the recommendation factor which influences
consumers- intention to purchase and to improve firm performances to
meet consumer needs.
Abstract: The purpose of this paper is to elucidate the flow unsteady behavior for moving plug in convergent-divergent variable thrust nozzle. Compressible axisymmetric Navier-Stokes equations are used to study this physical phenomenon. Different velocities are set for plug to investigate the effect of plug movement on flow unsteadiness. Variation of mass flow rate and thrust are compared under two conditions: First, the plug is placed at different positions and flow is simulated to reach the steady state (quasi steady simulation) and second, the plug is moved with assigned velocity and flow simulation is coupled with plug movement (unsteady simulation). If plug speed is high enough and its movement time scale is at the same order of the flow time scale, variation of the mass flow rate and thrust level versus plug position demonstrate a vital discrepancy under the quasi steady and unsteady conditions. This phenomenon should be considered especially from response time viewpoints in thrusters design.
Abstract: This study examines whether contrived success on a
task closely related to school subjects would promote students-
self-efficacy. In our previous study, junior high school students who
experienced contrived success on anagram tasks raised their sense of
self-efficacy and kept it high for a year.We tried to replicate that study,
substituting calculation tasks for the anagrams. One hundred eighteen
junior high school students participated in this study, 18 of whom were
surreptitiously given easier tasks than their classmates. Those students
with easier tasks outperformed their peers and thereby raised their
sense of self-efficacy. However, elevated self-efficacy did not persist,
falling to the starting level after only three months.
Abstract: A phorbol-12-myristate-13-acetate (TPA) is a synthetic analogue of phorbol ester (PE), a natural toxic compound of Euphorbiaceae plant. The oil extracted from plants of this family is useful source for primarily biofuel. However this oil might also be used as a foodstuff due to its significant nutrition content. The limitations for utilizing the oil as a foodstuff are mainly due to a toxicity of PE. Currently, a majority of PE detoxification processes are expensive as include multi steps alcohol extraction sequence.
Ozone is considered as a strong oxidative agent. It reacts with PE by attacking the carbon-carbon double bond of PE. This modification of PE molecular structure yields a non toxic ester with high lipid content.
This report presents data on development of simple and cheap PE detoxification process with water application as a buffer and ozone as reactive component. The core of this new technique is an application for a new microscale plasma unit to ozone production and the technology permits ozone injection to the water-TPA mixture in form of microbubbles.
The efficacy of a heterogeneous process depends on the diffusion coefficient which can be controlled by contact time and interfacial area. The low velocity of rising microbubbles and high surface to volume ratio allow efficient mass transfer to be achieved during the process. Direct injection of ozone is the most efficient way to process with such highly reactive and short lived chemical.
Data on the plasma unit behavior are presented and the influence of gas oscillation technology on the microbubble production mechanism has been discussed. Data on overall process efficacy for TPA degradation is shown.
Abstract: Feeder is one of the airships of the Multibody Advanced Airship for Transport (MAAT) system, under development within the EU FP7 project. MAAT is based on a modular concept composed of two different parts that have the possibility to join; respectively they are the so-called Cruiser and Feeder, designed on the lighter than air principle. Feeder, also named ATEN (Airship Transport Elevator Network), is the smaller one which joins the bigger one, Cruiser, also named PTAH (Photovoltaic modular Transport Airship for High altitude),envisaged to happen at 15km altitude. During the MAAT design phase, the aerodynamic studies of the both airships and their interactions are analyzed. The objective of these studies is to understand the aerodynamic behavior of all the preselected configurations, as an important element in the overall MAAT system design. The most of these configurations are only simulated by CFD, while the most feasible one is experimentally analyzed in order to validate and thrust the CFD predictions. This paper presents the numerical and experimental investigation of the Feeder “conical like" shape configuration. The experiments are focused on the aerodynamic force coefficients and the pressure distribution over the Feeder outer surface, while the numerical simulation cover also the analysis of the velocity and pressure distribution. Finally, the wind tunnel experiment is compared with its CFD model in order to validate such specific simulations with respective experiments and to better understand the difference between the wind tunnel and in-flight circumstances.
Abstract: This paper presents a text clustering system developed based on a k-means type subspace clustering algorithm to cluster large, high dimensional and sparse text data. In this algorithm, a new step is added in the k-means clustering process to automatically calculate the weights of keywords in each cluster so that the important words of a cluster can be identified by the weight values. For understanding and interpretation of clustering results, a few keywords that can best represent the semantic topic are extracted from each cluster. Two methods are used to extract the representative words. The candidate words are first selected according to their weights calculated by our new algorithm. Then, the candidates are fed to the WordNet to identify the set of noun words and consolidate the synonymy and hyponymy words. Experimental results have shown that the clustering algorithm is superior to the other subspace clustering algorithms, such as PROCLUS and HARP and kmeans type algorithm, e.g., Bisecting-KMeans. Furthermore, the word extraction method is effective in selection of the words to represent the topics of the clusters.
Abstract: In this paper, the concepts of dichotomous logistic
regression (DLR) with leave-one-out (L-O-O) were discussed. To
illustrate this, the L-O-O was run to determine the importance of the
simulation conditions for robust test of spread procedures with good
Type I error rates. The resultant model was then evaluated. The
discussions included 1) assessment of the accuracy of the model, and
2) parameter estimates. These were presented and illustrated by
modeling the relationship between the dichotomous dependent
variable (Type I error rates) with a set of independent variables (the
simulation conditions). The base SAS software containing PROC
LOGISTIC and DATA step functions can be making used to do the
DLR analysis.