Abstract: Sclareolide is made from sclareol by oxidiative synthesis and subsequent crystallization, while the crystallization mother liquor still contains 15%~30%wt of sclareolide to be reclaimed. With the reaction material of sclareol is provided as plant extract, many sorts of complex impurities exist in the mother liquor. Due to the difficulty in recycling sclareolide after solvent recovery, it is common practice for the factories to discard the mother liquor, which not only results in loss of sclareolide, but also contributes extra environmental burden. In this paper, a process based on adsorption and elution has been presented for recycling of sclareolide from mother liquor. After pretreatment of the crystallization mother liquor by HZ-845 resin to remove parts of impurities, sclareolide is adsorbed by HZ-816 resin. The HZ-816 resin loaded with sclareolide is then eluted by elution solvent. Finally, the eluent containing sclareolide is concentrated and fed into the crystallization step in the process. By adoption of the recycle from mother liquor, total yield of sclareolide increases from 86% to 90% with a stable purity of the final sclareolide products maintained.
Abstract: 10 clinically healthy hemal nodes were collected from male bulls aged 2-3 years. Light microscopy revealed a capsule of connective tissue consisted mainly of collagen fiber surrounding hemal node, numerous erythrocytes were found in wide subcapsular sinus under the capsule. The parenchyma of the hemal node was divided into cortex and medulla. Diffused lymphocytes, and lymphoid follicles, having germinal centers were the main components of the cortex, while in the medulla there was wide medullary sinus, diffused lymphocytes and few lymphoid nodules. The area occupied with lymph nodules was larger than that occupied with non-nodular structure of lymphoid cords and blood sinusoids. Electron microscopy revealed the cellular components of hemal node including elements of circulating erythrocytes intermingled with lymphocytes, plasma cells, mast cells, reticular cells, macrophages, megakaryocytes and endothelial cells lining the blood sinuses. The lymphocytes were somewhat triangular in shape with cytoplasmic processes extending between adjacent erythrocytes. Nuclei were triangular to oval in shape, lightly stained with clear nuclear membrane indentation and clear nucleoli. The reticular cells were elongated in shape with cytoplasmic processes extending between adjacent lymphocytes, rough endoplasmic reticulum, ribosomes and few lysosomes were seen in their cytoplasm. Nucleus was elongated in shape with less condensed chromatin. Plasma cells were oval to irregular in shape with numerous dilated rough endoplasmic reticulum containing electron lucent material occupying the whole cytoplasm and few mitochondria were found. Nuclei were centrally located and oval in shape with heterochromatin emarginated and often clumped near the nuclear membrane. Occasionally megakaryocytes and mast cells were seen among lymphocytes. Megakaryocytes had multilobulated nucleus and free ribosomes often appearing as small aggregates in their cytoplasm, while mast cell had their characteristic electron dense granule in the cytoplasm, few electron lucent granules were found also, we conclude that, the main function of the hemal node of cattle is proliferation of lymphocytes. No role for plasma cell in erythrophagocytosis could be suggested.
Abstract: Healthcare waste management continues to present an
array of challenges for developing countries, and Liberia is of no
exception. There is insufficient information available regarding the
generation, handling, and disposal of health care waste. This face
serves as an impediment to healthcare management schemes. The
specific objective of this study is to present an evaluation of the
current health care management practices in Liberia. It also presented
procedures, techniques used, methods of handling, transportation, and
disposal methods of wastes as well as the quantity and composition
of health care waste. This study was conducted as an investigative
case study, covering three different health care facilities; a hospital, a
health center, and a clinic in Monrovia, Montserrado County. The
average waste generation was found to be 0-7kg per day at the clinic
and health center and 8-15kg per/day at the hospital. The composition
of the waste includes hazardous and non-hazardous waste i.e. plastic,
papers, sharps, and pathological elements etc. Nevertheless, the
investigation showed that the healthcare waste generated by the
surveyed healthcare facilities were not properly handled because of
insufficient guidelines for separate collection, and classification, and
adequate methods for storage and proper disposal of generated
wastes. This therefore indicates that there is a need for improvement
within the healthcare waste management system to improve the
existing situation.
Abstract: Copreneurship is a term used to describe the business
pattern of operations run by married couples who share commitment,
goals, and responsibilities in handling a business. Research conducted
overseas showed that copreneurship business activities grew quickly
and played a role in elevating families’ and nations’ socio-economic
standards. In Malaysia, copreneurship has long been cultivated by
spouses. Thus, this study aimed to explore the factors that motivate
married partners to start a copreneurship business, and who is the
dominant partner in the management of this business. The study
participants are four entrepreneurial couples who are SME business
operators selected through purposive sampling. In-depth interviews
and direct observation were used as methods of measurement for
triangulation of qualitative data in this study. The findings of the
interviews were administered using NVivo 8.0 software. The result
shows that freedom is a key factor that drives entrepreneurs to set up
copreneurship businesses, and that the husband dominates the
management aspects of the business. The study gives an overview of
the parties involved in entrepreneurship to provide understanding of
the copreneurship concept as it is practiced. This study provides
academic value by creating understanding of the importance of a
harmonious family institution specifically for forming entrepreneurs
in the familial environment in Malaysia.
Abstract: The purpose of this paper is to show how state plays a
regulatory role in the relations of distribution by analyzing tax and
expenditure in Turkey. This paper has two main arguments. First,
state intervenes in economic and social life via budget policies and
steers the relations of distribution within the scope of the
reproduction of the capital accumulation and legitimacy. Secondly, a
great amount of public expenditure benefits capital owners while
state gains its tax income mainly from low and middle income
groups.
Abstract: This project aims at building an efficient and
automatic power monitoring SCADA system, which is capable of
monitoring the electrical parameters of high voltage powered devices
in real time for example RMS voltage and current, frequency, energy
consumed, power factor etc. The system uses RS-485 serial
communication interface to transfer data over longer distances.
Embedded C programming is the platform used to develop two
hardware modules namely: RTU and Master Station modules, which
both use the CC2540 BLE 4.0 microcontroller configured in slave /
master mode. The Si8900 galvanic ally isolated microchip is used to
perform ADC externally. The hardware communicates via UART
port and sends data to the user PC using the USB port. Labview
software is used to design a user interface to display current state of
the power loads being monitored as well as logs data to excel
spreadsheet file. An understanding of the Si8900’s auto baud rate
process is key to successful implementation of this project.
Abstract: The importance of culture and tourism in the attractiveness and competitiveness of the countries is central, and many regions are evidencing their cultural assets, tangible and intangible, as a means to create comparative advantages in tourism and produce a distinctive place in response to the pressures of globalization. Culture and tourism are interlinked because of their obvious combination and growth potential. Cultural tourism is a crucial global tourism market with fast growing. Regions can develop significant relations between culture and tourism to increase their attractiveness as places to visit, live and invest, increasing their competitiveness. Accordingly, having new and creative approach to historical areas as cultural value-based destinations can improve their conditions to promote tourism. Furthermore, in 21st century, media become the most important factor affecting the development of urban cities, including public places. As a result of the digital revolution, re-imaging and re-linkage public places by media are essential to create more interactions between public spaces and users, interaction media display, and urban screens, one of the most important defined media. This interaction can transform the urban space from being neglected to be more interactive space with users, especially the pedestrians. The paper focuses on The Walled City of Famagusta. As many other historic quarters elsewhere in the world, is in a process, of decay and deterioration, and its functionally distinctive areas are severely threatened by physical, functional, locational, and image obsolescence at varying degrees. So the focus on the future development of this area through tourism promotion can be an appropriate decision for the monument enhancement of the spatial quality in Walled City of Famagusta. In this paper, it is aimed to identify the effects of these new digital factors to transform public spaces especially in historic urban areas to promote creative tourism. Accordingly, two different analysis methods are used as well as a theoretical review. The first is case study on site and the second is Close ended questionnaire, test many concepts raised in this paper. The physical analysis on site carried out in order to evaluate the walled city restoration for touristic purpose. Besides, theoretical review is done in order to provide background to the subject and cleared Factors to attract tourists.
Abstract: Hydrologic models are increasingly used as tools to
predict stormwater quantity and quality from urban catchments.
However, due to a range of practical issues, most models produce
gross errors in simulating complex hydraulic and hydrologic systems.
Difficulty in finding a robust approach for model calibration is one of
the main issues. Though automatic calibration techniques are
available, they are rarely used in common commercial hydraulic and
hydrologic modelling software e.g. MIKE URBAN. This is partly
due to the need for a large number of parameters and large datasets in
the calibration process. To overcome this practical issue, a
framework for automatic calibration of a hydrologic model was
developed in R platform and presented in this paper. The model was
developed based on the time-area conceptualization. Four calibration
parameters, including initial loss, reduction factor, time of
concentration and time-lag were considered as the primary set of
parameters. Using these parameters, automatic calibration was
performed using Approximate Bayesian Computation (ABC). ABC is
a simulation-based technique for performing Bayesian inference
when the likelihood is intractable or computationally expensive to
compute. To test the performance and usefulness, the technique was
used to simulate three small catchments in Gold Coast. For
comparison, simulation outcomes from the same three catchments
using commercial modelling software, MIKE URBAN were used.
The graphical comparison shows strong agreement of MIKE URBAN
result within the upper and lower 95% credible intervals of posterior
predictions as obtained via ABC. Statistical validation for posterior
predictions of runoff result using coefficient of determination (CD),
root mean square error (RMSE) and maximum error (ME) was found
reasonable for three study catchments. The main benefit of using
ABC over MIKE URBAN is that ABC provides a posterior
distribution for runoff flow prediction, and therefore associated
uncertainty in predictions can be obtained. In contrast, MIKE
URBAN just provides a point estimate. Based on the results of the
analysis, it appears as though ABC the developed framework
performs well for automatic calibration.
Abstract: MicroRNAs are small non-coding RNA found in
many different species. They play crucial roles in cancer such as
biological processes of apoptosis and proliferation. The identification
of microRNA-target genes can be an essential first step towards to
reveal the role of microRNA in various cancer types. In this paper,
we predict miRNA-target genes for lung cancer by integrating
prediction scores from miRanda and PITA algorithms used as a
feature vector of miRNA-target interaction. Then, machine-learning
algorithms were implemented for making a final prediction. The
approach developed in this study should be of value for future studies
into understanding the role of miRNAs in molecular mechanisms
enabling lung cancer formation.
Abstract: The effect of upstream surface roughness over a
smooth forward facing step in an open channel was investigated
using a particle image velocimetry technique. Three different
upstream surface topographies consisting of hydraulically smooth
wall, sandpaper 36 grit and sand grains were examined. Besides the
wall roughness conditions, all other upstream flow characteristics
were kept constant. It was also observed that upstream roughness
decreased the approach velocity by 2% and 10% but increased the
turbulence intensity by 14% and 35% at the wall-normal distance
corresponding to the top plane of the step compared to smooth
upstream. The results showed that roughness decreased the
reattachment lengths by 14% and 30% compared to smooth upstream.
Although the magnitudes of maximum positive and negative
Reynolds shear stress in separated and reattached region were 0.02Ue
for all the cases, the physical size of both the maximum and
minimum contour levels were decreased by increasing upstream
roughness.
Abstract: The effectiveness of microchannels in enhancing heat
transfer has been demonstrated in the semiconductor industry. In
order to tap the microscale heat transfer effects into macro
geometries, overcoming the cost and technological constraints,
microscale passages were created in macro geometries machined
using conventional fabrication methods. A cylindrical insert was
placed within a pipe, and geometrical profiles were created on the
outer surface of the insert to enhance heat transfer under steady-state
single-phase liquid flow conditions. However, while heat transfer
coefficient values of above 10 kW/m2·K were achieved, the heat
transfer enhancement was accompanied by undesirable pressure drop
increment. Therefore, this study aims to address the high pressure
drop issue using Constructal theory, a universal design law for both
animate and inanimate systems. Two designs based on Constructal theory were developed to study
the effectiveness of Constructal features in reducing the pressure drop
increment as compared to parallel channels, which are commonly
found in microchannel fabrication. The hydrodynamic and heat
transfer performance for the Tree insert and Constructal fin (Cfin)
insert were studied using experimental methods, and the underlying
mechanisms were substantiated by numerical results. In technical
terms, the objective is to achieve at least comparable increment in
both heat transfer coefficient and pressure drop, if not higher
increment in the former parameter. Results show that the Tree insert improved the heat transfer
performance by more than 16 percent at low flow rates, as compared
to the Tree-parallel insert. However, the heat transfer enhancement
reduced to less than 5 percent at high Reynolds numbers. On the
other hand, the pressure drop increment stayed almost constant at 20
percent. This suggests that the Tree insert has better heat transfer
performance in the low Reynolds number region. More importantly,
the Cfin insert displayed improved heat transfer performance along
with favourable hydrodynamic performance, as compared to Cfinparallel
insert, at all flow rates in this study. At 2 L/min, the
enhancement of heat transfer was more than 30 percent, with 20
percent pressure drop increment, as compared to Cfin-parallel insert.
Furthermore, comparable increment in both heat transfer coefficient
and pressure drop was observed at 8 L/min. In other words, the Cfin
insert successfully achieved the objective of this study. Analysis of the results suggests that bifurcation of flows is
effective in reducing the increment in pressure drop relative to heat
transfer enhancement. Optimising the geometries of the Constructal
fins is therefore the potential future study in achieving a bigger stride
in energy efficiency at much lower costs.
Abstract: Flue gas desulfurization gypsum (FGD) is a waste
material arouse from coal power plants. Hydroxyapatite (HAP) is a
biomaterial with porous structure. In this study, FGD gypsum which
retrieved from coal power plant in Turkey was characterized and
HAP particles which can be used as an adsorbent in wastewater
treatment application were synthesized from the FGD gypsum. The
raw materials are characterized by using X Ray Diffraction (XRD)
and Fourier transform infrared spectroscopy (FT-IR) techniques and
produced HAP are characterized by using XRD. As a result, HAP
particles were synthesized at the molar ratio of 5:10, 5:15, 5:20, 5:24,
at room temperature, in alkaline medium (pH=11) and in 1 hour-reaction
time. Among these conditions, 5:20 had the best result.
Abstract: The objective of this research is to mitigate and prevent
the alkali silica reactivity (ASR) in highway construction projects.
ASR is a deleterious reaction initiated when the silica content of the
aggregate reacts with alkali hydroxides in cement in the presence of
relatively high moisture content. The ASR results in the formation of
an expansive white colored gel-like material which forms the
destructive tensile stresses inside hardened concrete. In this research, different types of local aggregates available in the
State of Arkansas were mixed and mortar bars were poured according
to the ASTM specifications. Mortar bars expansion was measured
versus time and aggregates with potential ASR problems were
detected. Different types of supplementary cementitious materials
(SCMs) were used in remixing mortar bars with highly reactive
aggregates. Length changes for remixed bars proved that different
types of SCMs can be successfully used in reducing the expansive
effect of ASR. SCMs percentage by weight is highly dependent on
the SCM type. The result of this study will help avoiding future
losses due to ASR cracking in construction project and reduce the
maintenance, repair, and replacement budgets required for highways
network.
Abstract: Device-to-device (D2D) communication is considered a
promising technique to provide wireless peer-to-peer communication
services. Due to increasing demand on mobile services, available
spectrum for radio frequency (RF) based communications becomes
scarce. Recently, visible light communications (VLC) has evolved
as a high speed wireless data transmission technology for indoor
environments with abundant available bandwidth. In this paper,
a novel VLC based D2D communication that provides wireless
peer-to-peer communication is proposed. Potential low operating
power devices for an efficient D2D communication over increasing
distance of separation between devices is analyzed. Optical repeaters
(OR) are also proposed to enhance the performance in an environment
where direct D2D communications yield degraded performance.
Simulation results show that VLC plays an important role in
providing efficient D2D communication up to a distance of 1 m
between devices. It is also found that the OR significantly improves
the coverage distance up to 3.5 m.
Abstract: In military aviation, the use of flight simulators has proliferated recently in order to train fifth generation fighter pilots. With these simulators, pilots can carry out real-time flights resulting in seeing their faults and can perform emergency drills prior to real flights. Since we cannot risk losing the aircraft and the pilot himself/herself in the flight training process, flight simulators are of great importance to adapt the fighter pilots competently to real flights aboard the fifth generation aircraft. The real flights are impossible to simulate thoroughly on the ground. To some extent, the fixed-based simulators may assist the pilot to steer aircraft technically and visually but flight simulators can’t trick the pilot’s vestibular, sensory, and perceptual systems without motion platforms. This paper discusses the benefits of motion simulators for fifth generation fighter pilots’ training in preference to the fixed-based counterparts by analyzing their pros and cons.
Abstract: Historic paths in today's cities are facing the pressure
of the urban development due to the rapid urban growth. Every new
development is tearing the old urban fabric and the socio-economic
character of the historic paths. Furthermore, in some cases historic
paths suffer from negligence and decay. Kom El Dekka historic path
was one of those deteriorated paths in the city of Alexandria, Egypt,
in spite of its high heritage and socio-economic value. Therefore,
there was a need to develop urban regeneration strategies as a part of
a wider sustainable development vision, to handle the situation and
revitalize the path as a livable space in the heart of the city. This
study aims to develop a comprehensive assessment methodology to
evaluate the different values of the path and to create community-oriented
and economic-based analysis methodology for its socio-economic
values. These analysis and assessments provide strategies
for any regeneration action plan for Kom El Dekka historic path.
Abstract: The Flexible AC Transmission System (FACTS)
technology is a new advanced solution that increases the reliability
and provides more flexibility, controllability, and stability of a power
system. The Unified Power Flow Controller (UPFC), as the most
versatile FACTS device for regulating power flow, is able to control
respectively transmission line real power, reactive power, and node
voltage. The main purpose of this paper is to analyze the effect of the
UPFC on the load flow, the power losses, and the voltage stability
using NEPLAN software modules, Newton-Raphson load flow is
used for the power flow analysis and the modal analysis is used for
the study of the voltage stability. The simulation was carried out on
the IEEE 14-bus test system.
Abstract: Autologous Chondrocyte Implantation (ACI) is used worldwide since 1998 to treat cartilage defect. GEL based ACI is a new tissue-engineering technique to treat full thickness cartilage defect with fibrin and thrombin as scaffold for chondrocytes. Purpose of this study is to see safety and efficacy of gel based ACI for knee cartilage defect in multiple centres with different surgeons. Gel-based Autologous Chondrocyte Implantation (GACI) has shown effectiveness in treating isolated cartilage defect of knee joint. Long term results are still needed to be studied. This study was followed-up up to two years and showed benefit to patients. All enrolled patients with a mean age of 28.5 years had an average defect size of3 square centimeters, and were grade IV as per ICRS grading. All patients were followed up several times and at several intervals at 6th week, 8th week, 11th week, 17th week, 29th week, 57th week after surgery. The outcomes were measured based on the IKDC (subjective and objective) and MOCART scores.
Abstract: Microstructure and fabric of soils play an important
role on structural properties e.g. stiffness and strength of compacted
earthwork. Traditional quality control monitoring based on moisturedensity
tests neither reflects the variability of soil microstructure nor
provides a direct assessment of structural property, which is the
ultimate objective of the earthwork quality control. Since stiffness
and strength are sensitive to soil microstructure and fabric, any
independent test methods that provide simple, rapid, and direct
measurement of stiffness and strength are anticipated to provide an
effective assessment of compacted earthen materials’ uniformity. In
this study, the soil stiffness gauge (SSG) and the dynamic cone
penetrometer (DCP) were respectively utilized to measure and
monitor the stiffness and strength in companion with traditional
moisture-density measurements of various earthen materials used in
Thailand road construction projects. The practical earthwork quality
control criteria are presented herein in order to assure proper
earthwork quality control and uniform structural property of
compacted earthworks.
Abstract: Community living adjacent to forests and Protected
Areas, especially in South Asian countries, have a common practice
in extracting resources for their living and livelihoods. This
extraction of resources, because the way it is done, destroys the biophysical
features of the area. Deforestation, wildlife poaching, illegal
logging, unauthorized hill cutting etc. are some of the serious issues
of concern for the sustainability of the natural resources that has a
direct impact on environment and climate as a whole. To ensure
community involvement in conservation initiatives of the state,
community based forest management, commonly known as Comanagement,
has been in practice in 6 South Asian countries. These
are -India, Nepal, Sri Lanka, Pakistan, Bhutan and Bangladesh.
Involving community in forestry management was initiated first in
Bangladesh in 1979 and reached as an effective co-management
approach through a several paradigm shifts. This idea of Comanagement
has been institutionalized through a Government Order
(GO) by the Ministry of Environment and Forests, Government of
Bangladesh on November 23, 2009. This GO clearly defines the
structure and functions of Co-management and its different bodies.
Bangladesh Forest Department has been working in association with
community to conserve and manage the Forests and Protected areas
of Bangladesh following this legal document. Demographically
young people constitute the largest segment of population in
Bangladesh. This group, if properly sensitized, can produce valuable
impacts on the conservation initiatives, both by community and
government. This study traced the major factors that motivate
community youths to work effectively with different tiers of comanagement
organizations in conservation of forests and Protected
Areas of Bangladesh. For the purpose of this study, 3 FGDs were
conducted with 30 youths from the community living around the
Protected Areas of Cox’s bazar, South East corner of Bangladesh,
who are actively involved in Co-management organizations. KII were
conducted with 5 key officials of Forest Department stationed at
Cox’s Bazar. 2 FGDs were conducted with the representatives of 7
Co-management organizations working in Cox’s Bazar region and
approaches of different community outreach activities conducted for
forest conservation by 3 private organizations and Projects have been
reviewed. Also secondary literatures were reviewed for the history
and evolution of Co-management in Bangladesh and six South Asian
countries. This study found that innovative community outreach
activities that are financed by public and private sectors involving
youths and community as a whole have played a pivotal role in
conservation of forests and Protected Areas of the region. This
approach can be replicated in other regions of Bangladesh as well as
other countries of South Asia where Co-Management exists in
practice.