Abstract: The computer modeling is carried out for parameter of
sensitivity of optoelectronic chemical and biosensors, using
phenomena of surface plasmon resonance (SPR). The physical model
of SPR-sensor-s is described with (or without) of modifications of
sensitive gold film surface by a dielectric layer. The variants of
increasing of sensitivity for SPR-biosensors, constructed on the
principle gold – dielectric – biomolecular layer are considered. Two
methods of mathematical treatment of SPR-curve are compared –
traditional, with estimation of sensor-s response as shift of the SPRcurve
minimum and proposed, for system with dielectric layer, using
calculating of the derivative in the point of SPR-curve half-width.