Abstract: Artemisinin is a potential antimalarial drug effective
against the multidrug resistant forms of Malarial Parasites. The
current production of artemisinin is insufficient to meet the global
demand. In the present study microbial biotransformation of
arteannuin B, a biogenetic precursor of artemisinin to the later has
been investigated. Screening studies carried out on several soil borne
microorganisms have yielded one novel species with the
bioconversion ability. Crude cell free extract of 72h old culture of the
isolate had shown the bioconversion activity. On incubation with the
substrate arteannuin B, crude cell free extract of the isolate had
shown a bioconversion of 18.54% to artemisinin on molar basis with
a specific activity of 0.18 units/mg.
Abstract: An application framework provides a reusable
design and implementation for a family of software systems.
Frameworks are introduced to reduce the cost of a product line
(i.e., family of products that share the common features). Software
testing is a time consuming and costly ongoing activity during the
application software development process. Generating reusable test
cases for the framework applications at the framework
development stage, and providing and using the test cases to test
part of the framework application whenever the framework is used
reduces the application development time and cost considerably.
Framework Interface Classes (FICs) are classes introduced by
the framework hooks to be implemented at the application
development stage. They can have reusable test cases generated at
the framework development stage and provided with the
framework to test the implementations of the FICs at the
application development stage. In this paper, we conduct a case
study using thirteen applications developed using three
frameworks; one domain oriented and two application oriented.
The results show that, in general, the percentage of the number of
FICs in the applications developed using domain frameworks is, on
average, greater than the percentage of the number of FICs in the
applications developed using application frameworks.
Consequently, the reduction of the application unit testing time
using the reusable test cases generated for domain frameworks is,
in general, greater than the reduction of the application unit testing
time using the reusable test cases generated for application
frameworks.
Abstract: In this paper, a near lossless image coding scheme
based on Orthogonal Polynomials Transform (OPT) has been
presented. The polynomial operators and polynomials basis operators
are obtained from set of orthogonal polynomials functions for the
proposed transform coding. The image is partitioned into a number of
distinct square blocks and the proposed transform coding is applied to
each of these individually. After applying the proposed transform
coding, the transformed coefficients are rearranged into a sub-band
structure. The Embedded Zerotree (EZ) coding algorithm is then
employed to quantize the coefficients. The proposed transform is
implemented for various block sizes and the performance is
compared with existing Discrete Cosine Transform (DCT) transform
coding scheme.
Abstract: The operating control parameters of injection
flushing type of electrical discharge machining process on stainless
steel 304 workpiece with copper tools are being optimized
according to its individual machining characteristic i.e. material
removal rate (MRR). Lower MRR during EDM machining process
may decrease its- machining productivity. Hence, the quality
characteristic for MRR is set to higher-the-better to achieve the
optimum machining productivity. Taguchi method has been used
for the construction, layout and analysis of the experiment for each
of the machining characteristic for the MRR. The use of Taguchi
method in the experiment saves a lot of time and cost of preparing
and machining the experiment samples. Therefore, an L18
Orthogonal array which was the fundamental component in the
statistical design of experiments has been used to plan the
experiments and Analysis of Variance (ANOVA) is used to
determine the optimum machining parameters for this machining
characteristic. The control parameters selected for this
optimization experiments are polarity, pulse on duration, discharge
current, discharge voltage, machining depth, machining diameter
and dielectric liquid pressure. The result had shown that the higher
the discharge voltage, the higher will be the MRR.
Abstract: One of the most important issues in multi-criteria decision analysis (MCDA) is to determine the weights of criteria so that all alternatives can be compared based on the collective performance of criteria. In this paper, one of popular methods in data envelopment analysis (DEA) known as common weights (CWs) is used to determine the weights in MCDA. Two frontiers named ideal and anti-ideal frontiers, instead of ideal and anti-ideal alternatives, are defined based on two new proposed CWs models. Ideal and antiideal frontiers are more flexible than that of alternatives. According to the optimal solutions of these two models, the distances of an alternative from the ideal and anti-ideal frontiers are derived. Then, a relative distance is introduced to measure the value of each alternative. The suggested models are linear and despite weight restrictions are feasible. An example is presented for explaining the method and for comparing to the existing literature.
Abstract: DNA microarray technology is widely used by
geneticists to diagnose or treat diseases through gene expression.
This technology is based on the hybridization of a tissue-s DNA
sequence into a substrate and the further analysis of the image
formed by the thousands of genes in the DNA as green, red or yellow
spots. The process of DNA microarray image analysis involves
finding the location of the spots and the quantification of the
expression level of these. In this paper, a tool to perform DNA
microarray image analysis is presented, including a spot addressing
method based on the image projections, the spot segmentation
through contour based segmentation and the extraction of relevant
information due to gene expression.
Abstract: New software protection product called “Obfuscation
Studio" is presented in the paper. Several obfuscating modules that
are already implemented are described. Some theoretical data is
presented, that shows the potency and effectiveness of described
obfuscation methods. “Obfuscation Studio" is being implemented for
protecting programs written for .NET platform, but the described
methods can also be interesting for other applications.
Abstract: The nanotechnology based on epitaxial systems
includes single or arranged misfit dislocations. In general, whatever
is the type of dislocation or the geometry of the array formed by the
dislocations; it is important for experimental studies to know exactly
the stress distribution for which there is no analytical expression [1,
2]. This work, using a numerical analysis, deals with relaxation of
epitaxial layers having at their interface a periodic network of edge
misfit dislocations. The stress distribution is estimated by using
isotropic elasticity. The results show that the thickness of the two
sheets is a crucial parameter in the stress distributions and then in the
profile of the two sheets.
A comparative study between the case of single dislocation and
the case of parallel network shows that the layers relaxed better when
the interface is covered by a parallel arrangement of misfit.
Consequently, a single dislocation at the interface produces an
important stress field which can be reduced by inserting a parallel
network of dislocations with suitable periodicity.
Abstract: Over the course of the past century, the global
automotive industry-s stance towards safety has evolved from one of
contempt to one nearing reverence. A suspension system that
provides safe handling and cornering capabilities can, with the help
of an efficient braking system, improve safety to a large extent. The
aim of this research is to propose a new automotive brake rotor
design and to compare it with automotive vented disk rotor. Static
structural and transient thermal analysis have been carried out on the
vented disk rotor and proposed rotor designs to evaluate and compare
their performance. Finite element analysis was employed for both
static structural and transient thermal analysis. Structural analysis
was carried out to study the stress and deformation pattern of the
rotors under extreme loads. Time varying temperature load was
applied on the rotors and the temperature distribution was analysed
considering cooling parameters (convection and radiation). This
dissertation illustrates the use of Finite Element Methods to examine
models, concluding with a comparative study of the proposed rotor
design and the conventional vented disk rotor for structural stability
and thermal efficiency.
Abstract: Polarization-interferometric nonlinear confocal
microscopy is proposed for measuring a nano-sized particle with
optical anisotropy. The anisotropy in the particle was
spectroscopically imaged through a three-dimensional distribution of
third-order nonlinear dielectric polarization photoinduced.
Abstract: An attempt has been made to beneficiate the Indian
coking coal fines by a combination of Spiral, flotation and Oleo
Flotation processes. Beneficiation studies were also carried out on -
0.5mm coal fines using flotation and oleo flotation by splitting at size
0.063mm.Size fraction of 0.5mm-0.063mm and -0.063mm size were
treated in flotation and Oleo flotation respectively. The washability
studies on the fraction 3-0.5 mm indicated that good separation may
be achieved when it is fed in a spiral. Combined product of Spiral,
Flotation and Oleo Flotation has given a significant yield at
acceptable ash%. Studies were also conducted to see the dewatering
of combined product by batch type centrifuge. It may further be
suggested that combination of different processes may be used to
treat the -3 mm fraction in an integrated manner to achieve the yield
at the desired ash level. The treatment of the 3/1 mm -0.5 mm size
fraction by spiral,-0.5-0.63 mm by conventional froth flotation and -
0.063 fractions by oleo flotation may provide a complete solution of
beneficiation and dewatering of coal fines, and can effectively
address the environmental problems caused by coal fines.
Abstract: The High Voltage (HV) transmission mains into the community necessitate earthing design to ensure safety compliance of the system. Concrete poles are widely used within HV transmission mains; which could have an impact on the earth grid impedance and input impedance of the system from the fault point of view. This paper provides information on concrete pole earthing to enhance the split factor of the system; further, it discusses the deployment of concrete structures in high soil resistivity area to reduce the earth grid system of the plant. This paper introduces the cut off soil resistivity SC ρ when replacing timber poles with concrete ones.
Abstract: It is well known that enhancing interfacial adhesion
between inorganic filler and matrix resin in a composite lead to
favorable properties such as excellent mechanical properties, high
thermal resistance, prominent electric insulation, low expansion
coefficient, and so on. But it should be avoided that much excess of
coupling agent is reacted due to a negative impact of their final
composite-s properties. There is no report to achieve classification of
the bonding state excepting investigation of coating layer thickness.
Therefore, the analysis of the bonding state of the coupling agent
reacted with the filler surface such as BN particles with less functional
group and silica particles having much functional group was
performed by thermal gravimetric analysis and pyrolysis GC/MS. The
reacted number of functional groups on the silane-coupling agent was
classified as a result of the analysis. Thus, we succeeded in classifying
the reacted number of the functional groups as a result of this study.
Abstract: For investigations of electromagnetic field
distributions in biological structures by Finite Element Method
(FEM), a method for automatic 3D model building of human
anatomical objects is developed. Models are made by meshed
structures and specific electromagnetic material properties for each
tissue type. Mesh is built according to specific FEM criteria for
achieving good solution accuracy. Several FEM models of
anatomical objects are built. Formulation using magnetic vector
potential and scalar electric potential (A-V, A) is used for modeling
of electromagnetic fields in human tissue objects. The developed
models are suitable for investigations of electromagnetic field
distributions in human tissues exposed in external fields during
magnetic stimulation, defibrillation, impedance tomography etc.
Abstract: Aim. We have introduced the notion of order to multinormed spaces and countable union spaces and their duals. The topology of bounded convergence is assigned to the dual spaces. The aim of this paper is to develop the theory of ordered topological linear
spaces La,b, L(w, z), the dual spaces of ordered multinormed spaces
La,b, ordered countable union spaces L(w, z), with the topology of bounded convergence assigned to the dual spaces. We apply Laplace transformation to the ordered linear space of Laplace transformable
generalized functions. We ultimately aim at finding solutions to nonhomogeneous
nth order linear differential equations with constant
coefficients in terms of generalized functions and comparing different
solutions evolved out of different initial conditions.
Method. The above aim is achieved by
• Defining the spaces La,b, L(w, z).
• Assigning an order relation on these spaces by identifying a
positive cone on them and studying the properties of the cone.
• Defining an order relation on the dual spaces La,b, L(w, z) of La,b, L(w, z) and assigning a topology to these dual spaces which makes the order dual and the topological dual the same. • Defining the adjoint of a continuous map on these spaces
and studying its behaviour when the topology of bounded
convergence is assigned to the dual spaces.
• Applying the two-sided Laplace Transformation on the ordered
linear space of generalized functions W and studying some
properties of the transformation which are used in solving
differential equations.
Result. The above techniques are applied to solve non-homogeneous
n-th order linear differential equations with constant coefficients in
terms of generalized functions and to compare different solutions of the differential equation.
Abstract: Research in e-Business has been growing
tremendously covering all related aspects such as adoption issues, e-
Business models, strategies, etc. This research aims to explore the
potential of adopting e-Business for a micro size business operating
from home called home-based businesses (HBBs). In Malaysia, the
HBB industry started many years ago and were mostly monopolized
by women or housewives managed as a part-time job to support their
family economy. Today, things have changed. The availability of the
Internet technology and the emergence of e-Business concept
promote the evolution of HBBs, which have been adopted as another
alternative as a professional career for women without neglecting
their family needs especially the children. Although this study is
confined to a limited sample size and within geographical biasness,
the findings show that it concurs with previous large scale studies. In
this study, both qualitative and quantitative methods were used and
data were gathered using triangulation methods via interview, direct
observation, document analysis and survey questionnaires. This paper
discusses the literature review, research methods and findings
pertaining to e-Business adoption factors that influence the HBBs in
Malaysia.
Abstract: The present disposal routes of sewage sludge represent a critical environmental issue in Egypt. Recently, there has been an increasing concern about sewage sludge management due to the environmental risks, which resulted from the fast expansion of wastewater treatment plants without equal attention in dealing with the produced sludge. This paper discusses the current situation of sewage sludge management in Egypt presenting a brief overview of the existing wastewater treatment plants, sludge production and characteristics as well as options of beneficial use and potential demand of sewage sludge under Egyptian conditions. The characteristics of sewage sludge are discussed considering the results of own sampling and analysis as well as previous studies. Furthermore, alternative treatment scenarios for sewage sludge, which have been recently developed in Egypt, are discussed and perspectives for a sustainable agricultural use are outlined.
Abstract: This paper proposes a feed-forward control in
resonant dc link inverter. The feed-forward control configuration is
based on synchronous sigma-delta modulation. The simulation
results showing the proposed technique can reject non-ideal dc bus
improving the total harmonic distortion.
Abstract: This paper presents the development of an active
vibration control using direct adaptive controller to suppress the
vibration of a flexible beam system. The controller is realized based
on linear parametric form. Differential evolution optimisation
algorithm is used to optimize the controller using single objective
function by minimizing the mean square error of the observed
vibration signal. Furthermore, an alternative approach is developed to
systematically search for the best controller model structure together
with it parameter values. The performance of the control scheme is
presented and analysed in both time and frequency domain.
Simulation results demonstrate that the proposed scheme is able to
suppress the unwanted vibration effectively.
Abstract: In this paper we introduce a new unit test technique
called déjà-vu object. Déjà-vu objects replace real objects used by
classes under test, allowing the execution of isolated unit tests. A
déjà-vu object is able to observe and record the behaviour of a real
object during real sessions, and to replace it during unit tests,
returning previously recorded results. Consequently déjà-vu object
technique can be useful when a bottom-up development and testing
strategy is adopted. In this case déjà-vu objects can increase test
portability and test source code readability. At the same time they
can reduce the time spent by programmers to develop test code and
the risk of incompatibility during the switching between déjà-vu and
production code.