PMF, Cesium and Rubidium Nanoparticles Induce Apoptosis in A549 Cells

Cancer becomes one of the leading cause of death in many countries over the world. Fourier-transform infrared (FTIR) spectra of human lung cancer cells (A549) treated with PMF (natural product extracted from PM 701) for different time intervals were examined. Second derivative and difference method were taken in comparison studies. Cesium (Cs) and Rubidium (Rb) nanoparticles in PMF were detected by Energy Dispersive X-ray attached to Scanning Electron Microscope SEM-EDX. Characteristic changes in protein secondary structure, lipid profile and changes in the intensities of DNA bands were identified in treated A549 cells spectra. A characteristic internucleosomal ladder of DNA fragmentation was also observed after 30 min of treatment. Moreover, the pH values were significantly increases upon treatment due to the presence of Cs and Rb nanoparticles in the PMF fraction. These results support the previous findings that PMF is selective anticancer agent and can produce apoptosis to A549 cells.

Investigating the Effectiveness of Iranian Architecture on Sustainable Space Creation

lack of convenience condition is one of the problems in open spaces in hot and dry regions. Nowadays parks and green landscapes was designed and constructed without any attention to convenience condition. If this process continues, Citizens will encounter with some problems. Harsh climatic condition decreases the efficiency of people-s activities. However there is hard environment condition in hot and dry regions, Convenience condition has been provided in Iranian traditional architecture by using techniques and methods. In this research at the first step characteristics of Iranian garden that can effect on creating sustainable spaces were investigated through observation method. Pleasure space in cities will be created with using these methods and techniques in future cities. Furthermore the comparison between Iranian garden and landscape in today-s cities demonstrate the effectiveness of Iranian garden characteristics on sustainable spaces. Iranian architects used simple and available methods for creating open architectural spaces. In addition desirable conditions were provided with taking in to account both physically and spiritually. Parks and landscapes in future cities can be designed and constructed with respect to architectural techniques that used in Iranian gardens in hot and arid regions.

Throughput Enhancement in AUDTWMN Using Throwboxes – An Overview

Delay and Disruption Tolerant Networking is part of the Inter Planetary Internet with primary application being Deep Space Networks. Its Terrestrial form has interesting research applications such as Alagappa University Delay Tolerant Water Monitoring Network which doubles as test beds for improvising its routing scheme. DTNs depend on node mobility to deliver packets using a store-carry-and forward paradigm. Throwboxes are small and inexpensive stationary devices equipped with wireless interfaces and storage. We propose the use of Throwboxes to enhance the contact opportunities of the nodes and hence improve the Throughput. The enhancement is evaluated using Alunivdtnsim, a desktop simulator in C language and the results are graphically presented.

Stress Intensity Factors for Plates with Collinear and Non-Aligned Straight Cracks

Multi-site damage (MSD) has been a challenge to aircraft, civil and power plant structures. In real life components are subjected to cracking at many vulnerable locations such as the bolt holes. However, we do not consider for the presence of multiple cracks. Unlike components with a single crack, these components are difficult to predict. When two cracks approach one another, their stress fields influence each other and produce enhancing or shielding effect depending on the position of the cracks. In the present study, numerical studies on fracture analysis have been conducted by using the developed code based on the modified virtual crack closure integral (MVCCI) technique and finite element analysis (FEA) software ABAQUS for computing SIF of plates with multiple cracks. Various parametric studies have been carried out and the results have been compared with literature where ever available and also with the solution, obtained by using ABAQUS. By conducting extensive numerical studies expressions for SIF have been obtained for collinear cracks and non-aligned cracks.

Modeling and Implementation of an Oceanic- Robot Glider

A glider is in essence an unpowered vehicle and in this project we designed and built an oceanic glider, designed to operate underwater. This Glider was designed to collect ocean data such as temperature, pressure and (in future measures physical dimensions of the operating environment) and output this data to an external source. Development of the Oceanic Glider required research into various actuation systems that control buoyancy, pitch and yaw and the dynamics of these systems. It also involved the design and manufacture of the Glider and the design and implementation of a controller that enabled the Glider to navigate and move in an appropriate manner.

Assessment of Health Risks to Ground Water Resources for the Emergency Supply of Population in Relation to the Content of Nitrates and Nitrites

The contents of nitrates and nitrites were monitored in 15 ground water resources of a selected region earmarked for the emergency supply of population. The resources have been selected on the basis of previous assessment of natural conditions and the exploitation of territory in the infiltration area as well as the surroundings of water resources. The health risk analysis carried out in relation to nitrates and nitrites, which were found to be the most serious water contaminants, proved, that 14 resources met the health standards in relation to the assessed criterion and could be included in crisis plans. Water quality of ground resources may be assessed in the same way with regard to other contaminants.

Improving the Performance of Proxy Server by Using Data Mining Technique

Currently, web usage make a huge data from a lot of user attention. In general, proxy server is a system to support web usage from user and can manage system by using hit rates. This research tries to improve hit rates in proxy system by applying data mining technique. The data set are collected from proxy servers in the university and are investigated relationship based on several features. The model is used to predict the future access websites. Association rule technique is applied to get the relation among Date, Time, Main Group web, Sub Group web, and Domain name for created model. The results showed that this technique can predict web content for the next day, moreover the future accesses of websites increased from 38.15% to 85.57 %. This model can predict web page access which tends to increase the efficient of proxy servers as a result. In additional, the performance of internet access will be improved and help to reduce traffic in networks.

Modification by the River Vaslui of the Hydrological Regime and Its Economic Implications (Romania)

The influence of human activities produced by dams along the river beds is minor, but the location of accumulation of water directly influences the hydrological regime. The most important effect of the influence of damming on the way water flows decreases the frequency of floods. The water rate controls the water flow of the dams. These natural reservoirs become dysfunctional and, as a result, a new distribution of flow in the downstream sector, where maximum flow is, brings about, in this case, higher values. In addition to fishing, middle and lower courses of rivers located by accumulation also have a role in mitigating flood waves, thus providing flood protection. The Vaslui also ensures a good part of the needs of the town water supply. The most important lake is Solesti, close to the Vaslui River, opened in 1974. A hydrological regime of accumulation is related to an anthropogenic and natural drainage system. The design conditions and their manoeuvres drain or fill the water courses.

Organoclay of Cetyl Trimethyl Ammonium- Montmorillonite: Preparation and Study in Adsorption of Benzene-Toluene-2-Chlorophenol

Contamination of aromatic compounds in water can cause severe long-lasting effects not only for biotic organism but also on human health. Several alternative technologies for remediation of polluted water have been attempted. One of these is adsorption process of aromatic compounds by using organic modified clay mineral. Porous structure of clay is potential properties for molecular adsorptivity and it can be increased by immobilizing hydrophobic structure to attract organic compounds. In this work natural montmorillonite were modified with cetyltrimethylammonium (CTMA+) and was evaluated for use as adsorbents of aromatic compounds: benzene, toluene, and 2-chloro phenol in its single and multicomponent solution by ethanol:water solvent. Preparation of CTMA-montmorillonite was conducted by simple ion exchange procedure and characterization was conducted by using x-day diffraction (XRD), Fourier-transform infra red (FTIR) and gas sorption analysis. The influence of structural modification of montmorillonite on its adsorption capacity and adsorption affinity of organic compound were studied. It was shown that adsorptivity of montmorillonite was increased by modification associated with arrangements of CTMA+ in the structure even the specific surface area of modified montmorillonite was lower than raw montmorillonite. Adsorption rate indicated that material has affinity to adsorb compound by following order: benzene> toluene > 2-chloro phenol. The adsorption isotherms of benzene and toluene showed 1st order adsorption kinetic indicating a partition phenomenon of compounds between the aqueous and organophilic CTMAmontmorillonite.

Experimental Studies on Treated Sub-base Soil with Fly Ash and Cement for Sustainable Design Recommendations

The pavement constructions on soft and expansive soils are not durable and unable to sustain heavy traffic loading. As a result, pavement failures and settlement problems will occur very often even under light traffic loading due to cyclic and rolling effects. Geotechnical engineers have dwelled deeply into this matter, and adopt various methods to improve the engineering characteristics of soft fine-grained soils and expansive soils. The problematic soils are either replaced by good and better quality material or treated by using chemical stabilization with various binding materials. Increased the strength and durability are also the part of the sustainability drive to reduce the environment footprint of the built environment by the efficient use of resources and waste recycle materials. This paper presents a series of laboratory tests and evaluates the effect of cement and fly ash on the strength and drainage characteristics of soil in Miri. The tests were performed at different percentages of cement and fly ash by dry weight of soil. Additional tests were also performed on soils treated with the combinations of fly ash with cement and lime. The results of this study indicate an increase in unconfined compression strength and a decrease in hydraulic conductivity of the treated soil.

The Effect of Leadership Styles on Continuous Improvement Teams

This research explorers the relationship between leadership style and continuous improvement (CI) teams. CI teams have several features that are not always found in other types of teams, including multi-functional members, short time period for performance, positive and actionable results, and exposure to senior leadership. There is no one best style of leadership for these teams. Instead, it is important to select the best leadership style for the situation. The leader must have the flexibility to change styles and the skill to use the chosen style effectively in order to ensure the team’s success.

A proposed High-Resolution Time-Frequency Distribution for the Analysis of Multicomponent and Speech Signals

In this paper, we propose a novel time-frequency distribution (TFD) for the analysis of multi-component signals. In particular, we use synthetic as well as real-life speech signals to prove the superiority of the proposed TFD in comparison to some existing ones. In the comparison, we consider the cross-terms suppression and the high energy concentration of the signal around its instantaneous frequency (IF).

An Automated High Pressure Differential Thermal Analysis System for Phase Transformation Studies

A piston cylinder based high pressure differential thermal analyzer system is developed to investigate phase transformations, melting, glass transitions, crystallization behavior of inorganic materials, glassy systems etc., at ambient to 4 GPa and at room temperature to 1073 K. The pressure is calibrated by the phase transition of bismuth and ytterbium and temperature is calibrated by using thermocouple data chart. The system developed is calibrated using benzoic acid, ammonium nitrate and it has a pressure and temperature control of ± 8.9 x 10 -4 GPa , ± 2 K respectively. The phase transition of Asx Te100-x chalcogenides, ferrous oxide and strontium boride are studied using the indigenously developed system.

Observer Design for Ecological Monitoring

Monitoring of ecological systems is one of the major issues in ecosystem research. The concepts and methodology of mathematical systems theory provide useful tools to face this problem. In many cases, state monitoring of a complex ecological system consists in observation (measurement) of certain state variables, and the whole state process has to be determined from the observed data. The solution proposed in the paper is the design of an observer system, which makes it possible to approximately recover the state process from its partial observation. The method is illustrated with a trophic chain of resource – producer – primary consumer type and a numerical example is also presented.

A Comparison of Experimental Data with Monte Carlo Calculations for Optimisation of the Sourceto- Detector Distance in Determining the Efficiency of a LaBr3:Ce (5%) Detector

Cerium-doped lanthanum bromide LaBr3:Ce(5%) crystals are considered to be one of the most advanced scintillator materials used in PET scanning, combining a high light yield, fast decay time and excellent energy resolution. Apart from the correct choice of scintillator, it is also important to optimise the detector geometry, not least in terms of source-to-detector distance in order to obtain reliable measurements and efficiency. In this study a commercially available 25 mm x 25 mm BrilLanCeTM 380 LaBr3: Ce (5%) detector was characterised in terms of its efficiency at varying source-to-detector distances. Gamma-ray spectra of 22Na, 60Co, and 137Cs were separately acquired at distances of 5, 10, 15, and 20cm. As a result of the change in solid angle subtended by the detector, the geometric efficiency reduced in efficiency with increasing distance. High efficiencies at low distances can cause pulse pile-up when subsequent photons are detected before previously detected events have decayed. To reduce this systematic error the source-to-detector distance should be balanced between efficiency and pulse pile-up suppression as otherwise pile-up corrections would need to be necessary at short distances. In addition to the experimental measurements Monte Carlo simulations have been carried out for the same setup, allowing a comparison of results. The advantages and disadvantages of each approach have been highlighted.

National Specific of Idioms in Kazakh and Korean Languages

It is well known that the phraseology of a language - the phenomenon of identity. This uniqueness is due to the fact that "there are idioms image-based views of reality that shows mainly of everyday empirical, historical and spiritual experience of a language community, associated with its cultural traditions. The article says that the phraseological units very clearly show the image of the people and give us a great view of the national identity. With the phraseology of the Kazakh and Korean language can understand the mentality of the nation, identity, perception of people. It is in the phraseological units can surprise the culture and customs of the people. Phraseological units store and transmit information about the level of material and spiritual culture of the people, his life, past and present, the development of society in general. And in Korean and Kazakh languages idioms occupy a particularly important role.

X-Ray Intensity Measurement Using Frequency Output Sensor for Computed Tomography

Quality of 2D and 3D cross-sectional images produce by Computed Tomography primarily depend upon the degree of precision of primary and secondary X-Ray intensity detection. Traditional method of primary intensity detection is apt to errors. Recently the X-Ray intensity measurement system along with smart X-Ray sensors is developed by our group which is able to detect primary X-Ray intensity unerringly. In this study a new smart X-Ray sensor is developed using Light-to-Frequency converter TSL230 from Texas Instruments which has numerous advantages in terms of noiseless data acquisition and transmission. TSL230 construction is based on a silicon photodiode which converts incoming X-Ray radiation into the proportional current signal. A current to frequency converter is attached to this photodiode on a single monolithic CMOS integrated circuit which provides proportional frequency count to incoming current signal in the form of the pulse train. The frequency count is delivered to the center of PICDEM FS USB board with PIC18F4550 microcontroller mounted on it. With highly compact electronic hardware, this Demo Board efficiently read the smart sensor output data. The frequency output approaches overcome nonlinear behavior of sensors with analog output thus un-attenuated X-Ray intensities could be measured precisely and better normalization could be acquired in order to attain high resolution.

A New Heuristic Approach for Large Size Zero-One Multi Knapsack Problem Using Intercept Matrix

This paper presents a heuristic to solve large size 0-1 Multi constrained Knapsack problem (01MKP) which is NP-hard. Many researchers are used heuristic operator to identify the redundant constraints of Linear Programming Problem before applying the regular procedure to solve it. We use the intercept matrix to identify the zero valued variables of 01MKP which is known as redundant variables. In this heuristic, first the dominance property of the intercept matrix of constraints is exploited to reduce the search space to find the optimal or near optimal solutions of 01MKP, second, we improve the solution by using the pseudo-utility ratio based on surrogate constraint of 01MKP. This heuristic is tested for benchmark problems of sizes upto 2500, taken from literature and the results are compared with optimum solutions. Space and computational complexity of solving 01MKP using this approach are also presented. The encouraging results especially for relatively large size test problems indicate that this heuristic can successfully be used for finding good solutions for highly constrained NP-hard problems.

Packing Theory for Natural and Crushed Aggregate to Obtain the Best Mix of Aggregate: Research and Development

Concrete performance is strongly affected by the particle packing degree since it determines the distribution of the cementitious component and the interaction of mineral particles. By using packing theory designers will be able to select optimal aggregate materials for preparing concrete with low cement content, which is beneficial from the point of cost. Optimum particle packing implies minimizing porosity and thereby reducing the amount of cement paste needed to fill the voids between the aggregate particles, taking also the rheology of the concrete into consideration. For reaching good fluidity superplasticizers are required. The results from pilot tests at Luleå University of Technology (LTU) show various forms of the proposed theoretical models, and the empirical approach taken in the study seems to provide a safer basis for developing new, improved packing models.

New Ways for Designing External Fixators Applied in Treatment of Open and Unstable Fractures

This paper deals with a new way for designing external fixators applied in traumatology and orthopaedics. These fixators can be applied in the treatment of open and unstable fractures or for lengthening human or animal bones etc. The new design is based on the development of Ilizarov and other techniques (i.e. shape and weight optimalization based on composite materials, application of smart materials, nanotechnology, low x-ray absorption, antibacterial protection, patient's comfort, reduction in the duration of the surgical treatment, and cost).