Abstract: Polypropylene blended with natural oil and pigment additives has been studied. Different formulations for each compound were made into polybag used for cultivation of oil palm seedlings for strength and mechanical properties studies. One group of sample was exposed under normal sunlight to initiate degradation and another group of sample was placed under shaded area for five months. All samples were tested for tensile strength to determine the degradation effects. The tensile strength of directly exposed sunlight samples and shaded area showed up to 50% and 25% degradation respectively. However, similar reduction of Young’s modulus for all samples was found for both exposures. Structural investigations were done using FTIR to detect deformation. The natural additives that were used in the studies were all natural and environmental friendly
Abstract: A new reverse phase-high performance liquid chromatography (RP-HPLC) method with fluorescent detector (FLD) was developed and optimized for Norfloxacin determination in human plasma. Mobile phase specifications, extraction method and excitation and emission wavelengths were varied for optimization. HPLC system contained a reverse phase C18 (5 μm, 4.6 mm×150 mm) column with FLD operated at excitation 330 nm and emission 440 nm. The optimized mobile phase consisted of 14% acetonitrile in buffer solution. The aqueous phase was prepared by mixing 2g of citric acid, 2g sodium acetate and 1 ml of triethylamine in 1 L of Milli-Q water was run at a flow rate of 1.2 mL/min. The standard curve was linear for the range tested (0.156–20 μg/mL) and the coefficient of determination was 0.9978. Aceclofenac sodium was used as internal standard. A detection limit of 0.078 μg/mL was achieved. Run time was set at 10 minutes because retention time of norfloxacin was 0.99 min. which shows the rapidness of this method of analysis. The present assay showed good accuracy, precision and sensitivity for Norfloxacin determination in human plasma with a new internal standard and can be applied pharmacokinetic evaluation of Norfloxacin tablets after oral administration in human.
Abstract: This article demonstrated development of
controlled release system of an NSAID drug, Diclofenac
sodium employing different ratios of Ethyl cellulose.
Diclofenac sodium and ethyl cellulose in different proportions
were processed by microencapsulation based on phase
separation technique to formulate microcapsules. The
prepared microcapsules were then compressed into tablets to
obtain controlled release oral formulations. In-vitro evaluation
was performed by dissolution test of each preparation was
conducted in 900 ml of phosphate buffer solution of pH 7.2
maintained at 37 ± 0.5 °C and stirred at 50 rpm. At predetermined
time intervals (0, 0.5, 1.0, 1.5, 2, 3, 4, 6, 8, 10, 12,
16, 20 and 24 hrs). The drug concentration in the collected
samples was determined by UV spectrophotometer at 276 nm.
The physical characteristics of diclofenac sodium
microcapsules were according to accepted range. These were
off-white, free flowing and spherical in shape. The release
profile of diclofenac sodium from microcapsules was found to
be directly proportional to the proportion of ethylcellulose and
coat thickness. The in-vitro release pattern showed that with
ratio of 1:1 and 1:2 (drug: polymer), the percentage release of
drug at first hour was 16.91 and 11.52 %, respectively as
compared to 1:3 which is only 6.87 % with in this time. The
release mechanism followed higuchi model for its release
pattern. Tablet Formulation (F2) of present study was found
comparable in release profile the marketed brand Phlogin-SR,
microcapsules showed an extended release beyond 24 h.
Further, a good correlation was found between drug release
and proportion of ethylcellulose in the microcapsules.
Microencapsulation based on coacervation found as good
technique to control release of diclofenac sodium for making
the controlled release formulations.
Abstract: Flow field around hypersonic vehicles is very
complex and difficult to simulate. The boundary layers are squeezed
between shock layer and body surface. Resolution of boundary layer,
shock wave and turbulent regions where the flow field has high
values is difficult of capture. Detached eddy simulation (DES) is a
modification of a RANS model in which the model switches to a
subgrid scale formulation in regions fine enough for LES
calculations. Regions near solid body boundaries and where the
turbulent length scale is less than the maximum grid dimension are
assigned the RANS mode of solution. As the turbulent length scale
exceeds the grid dimension, the regions are solved using the LES
mode. Therefore the grid resolution is not as demanding as pure LES,
thereby considerably cutting down the cost of the computation. In
this research study hypersonic flow is simulated at Mach 8 and
different angle of attacks to resolve the proper boundary layers and
discontinuities. The flow is also simulated in the long wake regions.
Mesh is little different than RANS simulations and it is made dense
near the boundary layers and in the wake regions to resolve it
properly. Hypersonic blunt cone cylinder body with frustrum at angle
5o and 10 o are simulated and there aerodynamics study is performed
to calculate aerodynamics characteristics of different geometries. The
results and then compared with experimental as well as with some
turbulence model (SA Model). The results achieved with DES
simulation have very good resolution as well as have excellent
agreement with experimental and available data. Unsteady
simulations are performed for DES calculations by using duel time
stepping method or implicit time stepping. The simulations are
performed at Mach number 8 and angle of attack from 0o to 10o for
all these cases. The results and resolutions for DES model found
much better than SA turbulence model.
Abstract: An early and accurate detection of Alzheimer's disease (AD) is an important stage in the treatment of individuals suffering from AD. We present an approach based on the use of structural magnetic resonance imaging (sMRI) phase images to distinguish between normal controls (NC), mild cognitive impairment (MCI) and AD patients with clinical dementia rating (CDR) of 1. Independent component analysis (ICA) technique is used for extracting useful features which form the inputs to the support vector machines (SVM), K nearest neighbour (kNN) and multilayer artificial neural network (ANN) classifiers to discriminate between the three classes. The obtained results are encouraging in terms of classification accuracy and effectively ascertain the usefulness of phase images for the classification of different stages of Alzheimer-s disease.
Abstract: Green home rating has emerged as an important
agenda to practice the principles of sustainability. In Malaysia, the
establishment of the 'Green Building Index ' Residential New
Construction- (GBI-RNC) has brought this agenda closer to the
stakeholders of the local green building industry. GBI-RNC focuses
on the evaluation of the environmental impacts posed by houses
rather than assessing the Triple-Bottom-Line (TBL) of Sustainability
which also include socio-economic factors. Therefore, as part of a
wider study, a survey was conducted to gather the backgrounds of
green building stakeholders in Malaysia and their responses to a
number of exploratory questions regarding the setting up of a
framework to rate green homes against the TBL. This paper reports
the findings from Section A and B from this survey and discusses
them accordingly with a conclusion that forms part of the basis for a
new generation green home rating framework specifically for use in
Malaysia.
Abstract: Occurrence of a multiple-points fault in machine operations could result in exhibiting complex fault signatures, which could result in lowering fault diagnosis accuracy. In this study, a multiple-points defect model (MPDM) is proposed which can simulate fault signature-s dynamics for n-points bearing faults. Furthermore, this study identifies that in case of multiple-points fault in the rotary machine, the location of the dominant component of defect frequency shifts depending upon the relative location of the fault points which could mislead the fault diagnostic model to inaccurate detections. Analytical and experimental results are presented to characterize and validate the variation in the dominant component of defect frequency. Based on envelop detection analysis, a modification is recommended in the existing fault diagnostic models to consider the multiples of defect frequency rather than only considering the frequency spectrum at the defect frequency in order to incorporate the impact of multiple points fault.
Abstract: Data mining has been used very frequently to extract
hidden information from large databases. This paper suggests the use
of decision trees for continuously extracting the clinical reasoning in
the form of medical expert-s actions that is inherent in large number
of EMRs (Electronic Medical records). In this way the extracted data
could be used to teach students of oral medicine a number of orderly
processes for dealing with patients who represent with different
problems within the practice context over time.
Abstract: Requirements management is critical to software
delivery success and project lifecycle. Requirements management
and their traceability provide assistance for many software
engineering activities like impact analysis, coverage analysis,
requirements validation and regression testing. In addition
requirements traceability is the recognized component of many
software process improvement initiatives. Requirements traceability
also helps to control and manage evolution of a software system.
This paper aims to provide an evaluation of current requirements
management and traceability tools. Management and test managers
require an appropriate tool for the software under test. We hope,
evaluation identified here will help to select the efficient and
effective tool.
Abstract: The current work focuses on rephrasing the harmful
effects of mercury that is being released from a number of sources.
Most of the sources are from the industrial waste water. Different
techniques of mercury removal have been discussed and a brief
comparison among these has been made. The experimental work has
been conducted for two most widely used methods of mercury
removal and comparison in terms of their efficiency has been made.
Abstract: This paper introduces and proves new concept of salt
dissolving in water as very tiny solid sodium chloride particles of
nanovolumes, from this point of view salt water can be desalinated by
collision with special surface characterized by smoothness upon nano
level, high rigidity, high hardness under appropriate conditions of
water launching in the form of thin laminar flow under suitable speed
and angle of incidence to get desalinated water.
Abstract: The purpose of the present work was to study the
production and process parameters optimization for the synthesis of
cellulase from Trichoderma viride in solid state fermentation (SSF)
using an agricultural wheat straw as substrates; as fungal conversion
of lignocellulosic biomass for cellulase production is one among the
major increasing demand for various biotechnological applications.
An optimization of process parameters is a necessary step to get
higher yield of product. Several kinetic parameters like pretreatment,
extraction solvent, substrate concentration, initial moisture content,
pH, incubation temperature and inoculum size were optimized for
enhanced production of third most demanded industrially important
cellulase. The maximum cellulase enzyme activity 398.10±2.43
μM/mL/min was achieved when proximally analyzed lignocellulosic
substrate wheat straw inocubated at 2% HCl as pretreatment tool
along with distilled water as extraction solvent, 3% substrate
concentration 40% moisture content with optimum pH 5.5 at 45°C
incubation temperature and 10% inoculum size.
Abstract: This paper introduces the effective speckle reduction of
synthetic aperture radar (SAR) images using inner product spaces in
undecimated wavelet domain. There are two major areas in projection
onto span algorithm where improvement can be made. First is the use
of undecimated wavelet transformation instead of discrete wavelet
transformation. And second area is the use of smoothing filter namely
directional smoothing filter which is an additional step. Proposed
method does not need any noise estimation and thresholding
technique. More over proposed method gives good results on both
single polarimetric and fully polarimetric SAR images.
Abstract: Fossil fuels are the major source to meet the world
energy requirements but its rapidly diminishing rate and adverse
effects on our ecological system are of major concern. Renewable
energy utilization is the need of time to meet the future challenges.
Ocean energy is the one of these promising energy resources. Threefourths
of the earth-s surface is covered by the oceans. This enormous
energy resource is contained in the oceans- waters, the air above the
oceans, and the land beneath them. The renewable energy source of
ocean mainly is contained in waves, ocean current and offshore solar
energy. Very fewer efforts have been made to harness this reliable
and predictable resource. Harnessing of ocean energy needs detail
knowledge of underlying mathematical governing equation and their
analysis. With the advent of extra ordinary computational resources
it is now possible to predict the wave climatology in lab simulation.
Several techniques have been developed mostly stem from numerical
analysis of Navier Stokes equations. This paper presents a brief over
view of such mathematical model and tools to understand and
analyze the wave climatology. Models of 1st, 2nd and 3rd generations
have been developed to estimate the wave characteristics to assess the
power potential. A brief overview of available wave energy
technologies is also given. A novel concept of on-shore wave energy
extraction method is also presented at the end. The concept is based
upon total energy conservation, where energy of wave is transferred
to the flexible converter to increase its kinetic energy. Squeezing
action by the external pressure on the converter body results in
increase velocities at discharge section. High velocity head then can
be used for energy storage or for direct utility of power generation.
This converter utilizes the both potential and kinetic energy of the
waves and designed for on-shore or near-shore application. Increased
wave height at the shore due to shoaling effects increases the
potential energy of the waves which is converted to renewable
energy. This approach will result in economic wave energy
converter due to near shore installation and more dense waves due to
shoaling. Method will be more efficient because of tapping both
potential and kinetic energy of the waves.
Abstract: This research contribution propels the idea of collaborating environment for the execution of student satellite projects in the backdrop of project management principles. The recent past has witnessed a technological shift in the aerospace industry from the big satellite projects to the small spacecrafts especially for the earth observation and communication purposes. This vibrant shift has vitalized the academia and industry to share their resources and to create a win-win paradigm of mutual success and technological development along with the human resource development in the field of aerospace. Small student satellites are the latest jargon of academia and more than 100 CUBESAT projects have been executed successfully all over the globe and many new student satellite projects are in the development phase. The small satellite project management requires the application of specific knowledge, skills, tools and techniques to achieve the defined mission requirements. The Authors have presented the detailed outline for the project management of student satellites and presented the role of industry to collaborate with the academia to get the optimized results in academic environment.
Abstract: This paper introduces an isolated and unique ancient language Burushaski, spoken in Hunza, Nagar, Yasin and parts of Gilgit in the Northern Areas of Pakistan. It explains the working mechanism of Multi Language Text Editor for Urdu and Burushaski. It is developed under the use of ISO/IEC 10646 Unicode standards for Urdu and Burushaski open-type fonts. It gives an ample opportunity to this regional ancient language to have a modern Information technology for its promotion and preservation. The main objective of this research paper is to help preserve the heritage of such rare languages and give smart way of automation. It also facilitates to those who are interested in undertaking research on Burushaski or keen to trace fonatic relationship between the national Urdu language and Burushaski. Since this editor covers both Burushaski and Urdu so it can play an important role to introduce Burusho linguistic culture to the world at large. Precisely, as a result of this research paper, Burushaski publication through IT means would be possible.
Abstract: The present study was conducted to observe the effect
of Plantago psyllium on blood glucose and cholesterol levels in
normal and alloxan induced diabetic rats. To investigate the effect of
Plantago psyllium 40 rats were included in this study divided into
four groups of ten rats in each group. One group A was normal,
second group B was diabetic, third group C was non diabetic and
hypercholesterolemic and fourth group D was diabetic and
hypercholesterolemic. Two groups B and D were made diabetic by
intraperitonial injection of alloxan dissolved in 1mL distilled water at
a dose of 125mg/Kg of body weight. Two groups C and D were
made hypercholesterolemic by oral administration of powder
cholesterol (1g/Kg of body weight). The blood samples from all the
rats were collected from coccygial vein on 1st day, then on 21st and
42nd day respectively. All the samples were analyzed for blood
glucose and cholesterol level by using enzymatic kits. The blood
glucose and cholesterol levels of treated groups of rats showed
significant reduction after 7 weeks of treatment with Plantago
psyllium. By statistical analysis of results it was found that Plantago
psyllium has anti-diabetic and hypocholesterolemic activity in
diabetic and hypercholesterolemic albino rats.
Abstract: In this study, structural, mechanical, thermal and
electrical properties of poly (lactic acid) (PLA) nanocomposites with
low-loaded (0-1.5 wt%) untreated, heat and nitric acid treated multiwalled
carbon nanotubes (MWCNTs) were studied. Among the
composites, untreated 0.5 wt % MWCNTs and acid-treated 1.0 wt%
MWCNTs reinforced PLA show the tensile strength and modulus
values higher than the others. These two samples along with pure
PLA exhibit the stable orthorhombic α-form, whilst other samples
reveal the less stable orthorhombic β-form, as demonstrated by X-ray
diffraction study. Differential scanning calorimetry reveals the
evolution of the mentioned different phases by controlled cooling and
discloses an enhancement of PLA crystallization by nanotubes
incorporation. Thermogravimetric analysis shows that the MWCNTs
loaded sample degraded faster than PLA. Surface resistivity of the
nanocomposites is found to be dropped drastically by a factor of 1013
with a low loading of MWCNTs (1.5 wt%).
Abstract: An approach to develop the FPGA of a flexible key
RSA encryption engine that can be used as a standard device in the
secured communication system is presented. The VHDL modeling of
this RSA encryption engine has the unique characteristics of
supporting multiple key sizes, thus can easily be fit into the systems
that require different levels of security. A simple nested loop addition
and subtraction have been used in order to implement the RSA
operation. This has made the processing time faster and used
comparatively smaller amount of space in the FPGA. The hardware
design is targeted on Altera STRATIX II device and determined that
the flexible key RSA encryption engine can be best suited in the
device named EP2S30F484C3. The RSA encryption implementation
has made use of 13,779 units of logic elements and achieved a clock
frequency of 17.77MHz. It has been verified that this RSA
encryption engine can perform 32-bit, 256-bit and 1024-bit
encryption operation in less than 41.585us, 531.515us and 790.61us
respectively.
Abstract: The purpose of the study was to investigate the
effectiveness of ICT training workshop of tutors of Allama Iqbal
Open University Pakistan. The study was delimited to tutors of
Multan region. The total sample comprised of 100 tutors. All the
tutors who participated in ICT training workshop in Multan region
were taken as sample in the study. A questionnaire having two parts,
based on five point rating scale was developed by the researcher. Part
one was about the competency level of computer skills while Part
two was based on items related to training delivery, structure and
content. Part One of questionnaire had five levels of competency
about computer skills. The questionnaire was personally administered
and collected back by the researcher himself on the last day of
workshop.
The collected data were analyzed by using descriptive statistics.
Through this study it was found that majority of the tutors strongly
agreed that training enhanced their computer skills. Majority of the
respondents consider themselves to be generally competent in the use
of computer. They also agreed that there was appropriate
infrastructure and technical support in lab during training workshop.
Moreover, it was found that the training imparted the knowledge of
pedagogy of using computers for distance education.