Abstract: One of the major disadvantages of the minimally
invasive surgery (MIS) is the lack of tactile feedback to the surgeon.
In order to identify and avoid any damage to the grasped complex
tissue by endoscopic graspers, it is important to measure the local
softness of tissue during MIS. One way to display the measured
softness to the surgeon is a graphical method. In this paper, a new
tactile sensor has been reported. The tactile sensor consists of an
array of four softness sensors, which are integrated into the jaws of a
modified commercial endoscopic grasper. Each individual softness
sensor consists of two piezoelectric polymer Polyvinylidene Fluoride
(PVDF) films, which are positioned below a rigid and a compliant
cylinder. The compliant cylinder is fabricated using a micro molding
technique. The combination of output voltages from PVDF films is
used to determine the softness of the grasped object. The theoretical
analysis of the sensor is also presented.
A method has been developed with the aim of reproducing the
tactile softness to the surgeon by using a graphical method. In this
approach, the proposed system, including the interfacing and the data
acquisition card, receives signals from the array of softness sensors.
After the signals are processed, the tactile information is displayed
by means of a color coding method. It is shown that the degrees of
softness of the grasped objects/tissues can be visually differentiated
and displayed on a monitor.
Abstract: The aim of this study is evaluating the antinociceptive
and anti-inflamatory activity of Geum kokanicum. After
determination total extract LD50, different doses of extract were
chosen for intrapritoneal injections. In inflammation test, male NMRI
mice were divided into 6 groups: control (normal saline), positive
control (Dexamethasone 15mg/kg), and total extract (0.025, 0.05,
0.1, and 0.2 gr/kg). The inflammation was produced by xyleneinduced
edema. In order to evaluate the antinociceptive effect of total
extract, formalin test was used. Mice were divided into 6 groups:
control, positive control (morphine 10mg/kg), and 4 groups which
received total extract. Then they received Formalin. The animals
were observed for the reaction to pain. Data were analyzed using
One-way ANOVA followed by Tukey-Kramer multiple comparison
test. LD50 was 1 gr/kg. Data indicated that 0.5,0.1 and 0.2 gr/kg
doses of total extract have particular antinociceptive and antiinflammatory
effects in a comparison with control (P
Abstract: In present study the effects of anti-inflammatory and
antinociceptive of vitex hydro-alcoholic extract were evaluated on
male mice. In inflammatory test mice were divided into 7 groups:
first group was control. The second group, positive control group,
received dexamethasone (15 mg/kg) and the other five groups
received different doses of hydroalcohol extract of Vitex fruit (265,
365, 465, 565, and 665 mg/kg). The inflammation was caused by
xylene-induced ear edema. Formalin test was used for evaluation of
antinociceptive effect of extract. In this test, mice were divided into 7
groups: control, morphine (10mg/kg) as positive control group, and
Vitex extract groups ((265, 365, 465, 565, and 665 mg/kg). All drugs
were administered intrapritoneally, 30 min before each test. The data
were analyzed using one-way ANOVA followed by Tukey-kramer
multiple comparison test. Results have shown significant antiinflammatory
effects of extract at all dosed as compared with control
(P