Abstract: Liposomal magnetofection is a simple, highly efficient
technology for cell transfection, demonstrating better outcome than a
number of other common gene delivery methods. However,
aggregate complexes distribution over the cell surface is non-uniform
due to the gradient of the permanent magnetic field. The aim of this
study was to estimate the efficiency of liposomal magnetofection for
prostate carcinoma PC3 cell line using newly designed device,
“DynaFECTOR", ensuring magnetofection in a dynamic gradient
magnetic field. Liposomal magnetofection in a dynamic gradient
magnetic field demonstrated the highest transfection efficiency for
PC3 cells – it increased for 21% in comparison with liposomal
magnetofection and for 42% in comparison with lipofection alone.
The optimal incubation time under dynamic magnetic field for PC3
cell line was 5 minutes and the optimal rotation frequency of
magnets – 5 rpm. The new approach also revealed lower cytotoxic
effect to cells than liposomal magnetofection.
Abstract: In CMOS integrated circuit design there is a trade-off between static power consumption and technology scaling. Recently, the power density has increased due to combination of higher clock speeds, greater functional integration, and smaller process geometries. As a result static power consumption is becoming more dominant. This is a challenge for the circuit designers. However, the designers do have a few methods which they can use to reduce this static power consumption. But all of these methods have some drawbacks. In order to achieve lower static power consumption, one has to sacrifice design area and circuit performance. In this paper, we propose a new method to reduce static power in the CMOS VLSI circuit using Variable Body Biasing technique without being penalized in area requirement and circuit performance.
Abstract: Electrochemical-oxidation of Reactive Black-5 (RB- 5) was conducted for degradation using DSA type Ti/RuO2-SnO2- Sb2O5 electrode. In the study, for electro-oxidation, electrode was indigenously fabricated in laboratory using titanium as substrate. This substrate was coated using different metal oxides RuO2, Sb2O5 and SnO2 by thermal decomposition method. Laboratory scale batch reactor was used for degradation and decolorization studies at pH 2, 7 and 11. Current density (50mA/cm2) and distance between electrodes (8mm) were kept constant for all experiments. Under identical conditions, removal of color, COD and TOC at initial pH 2 was 99.40%, 55% and 37% respectively for initial concentration of 100 mg/L RB-5. Surface morphology and composition of the fabricated electrode coatings were characterized using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) respectively. Coating microstructure was analyzed by X-ray diffraction (XRD). Results of this study further revealed that almost 90% of oxidation occurred within 5-10 minutes.
Abstract: Arenga pinnata is an abundantly natural fiber that can be used for sound proof material. However, the scientific data of acoustics properties of Arenga pinnata was not available yet. In this study the sound absorption of pure arenga pinnata was measured. The thickness of Arenga pinnata was varied in 10 mm, 20 mm, 30mm, and 40mm. This work was carried out to investigate the potential of using Arenga pinnata fiber as raw material for sound absorbing material. Impedance Tube Method was used to measure sound absorption coefficient (α). The Measurements was done in accordance with ASTM E1050-98, that is the standard test method for impedance and absorption of acoustical materials using a tube, two microphones and a digital frequency analysis system . The results showed that sound absorption coefficients of Arenga pinnata were good from 2000 Hz to 5000 Hz within the range of 0.75 – 0.90. The optimum sound absorption coefficient was obtained from the thickness of 40 mm. These results indicated that Arenga pinnata fiber is promising to be used as raw material of sound absorbing material with low cost, light, and biodegradable.
Abstract: This paper presents the development of a hybrid
thermal model for the EVO Electric AFM 140 Axial Flux Permanent
Magnet (AFPM) machine as used in hybrid and electric vehicles. The
adopted approach is based on a hybrid lumped parameter and finite
difference method. The proposed method divides each motor
component into regular elements which are connected together in a
thermal resistance network representing all the physical connections
in all three dimensions. The element shape and size are chosen
according to the component geometry to ensure consistency. The
fluid domain is lumped into one region with averaged heat transfer
parameters connecting it to the solid domain. Some model parameters
are obtained from Computation Fluid Dynamic (CFD) simulation and
empirical data. The hybrid thermal model is described by a set of
coupled linear first order differential equations which is discretised
and solved iteratively to obtain the temperature profile. The
computation involved is low and thus the model is suitable for
transient temperature predictions. The maximum error in temperature
prediction is 3.4% and the mean error is consistently lower than the
mean error due to uncertainty in measurements. The details of the
model development, temperature predictions and suggestions for
design improvements are presented in this paper.
Abstract: A study concerning the photocatalytic decolourization
of Congo red (CR) dye, over artificial UV irradiation is presented.
Photocatalysts based on a commercial titanium dioxide (TiO2)
modified with transition metals (Ni, Cu and Zn) were used. The
dopage method used was wet impregnation. A TiO2 sample without
salt was subjected to the same hydrothermal treatment to be used as
reference. Congo red solutions to several pH conditions (natural and
basic) were used to evaluate photocatalytic performance of each
doped catalysts. Photodecolourization percentage was measured
spectrofotrometically after 3 h of treatment to 499 nm as response
variable. Kinetics investigations of photodegradation indicated that
reactions obey to Langmuir-Hinshelwood model and pseudo–first
order law. The rate constant studies of photocatalytic decolourization
reactions for Zn–TiO2 and Cu–TiO2 photocatalysts indicated that in
all cases the rate constant of the reaction was higher than that of TiO2
undoped. These results show that nature of the metal modifying the
TiO2 influence on the efficiency of the photocatalyst evaluated in
process. Ni does not present an additional effect compared with TiO2,
while Zn enhances the photoactivity due to its electronic properties.
Abstract: Each new semiconductor technology node
brings smaller transistors and wires. Although this makes
transistors faster, wires get slower. In nano-scale regime, the
standard copper (Cu) interconnect will become a major hurdle
for FPGA interconnect due to their high resistivity and
electromigration. This paper presents the comprehensive
evaluation of mixed CNT bundle interconnects and
investigates their prospects as energy efficient and high speed
interconnect for future FPGA routing architecture. All
HSPICE simulations are carried out at operating frequency of
1GHz and it is found that mixed CNT bundle implemented in
FPGAs as interconnect can potentially provide a substantial
delay and energy reduction over traditional interconnects at
32nm process technology.
Abstract: The load flow study in a power system constitutes a study of paramount importance. The study reveals the electrical performance and power flows (real and reactive) for specified condition when the system is operating under steady state. This paper gives an overview of different techniques used for load flow study under different specified conditions.
Abstract: Introduction: Visual performance is an important factor in sport excellence. Visual involvement in a sport varies according to environmental demands associated with that sport. These environmental demands are matched by a task specific motor response. The purpose of this study was to determine if sport specific exercises will improve the visual performance of male rugby players, in order to achieve maximal results on the sports field. Materials & Methods: Twenty six adult male rugby players, aged 16-22, were chosen as subjects. In order to evaluate the effect of sport specific exercises on visual skills, a pre-test - post-test experimental group design was adopted for the study. Results: Significant differences (p≤0.05) were seen in the focussing, tracking, vergence, sequencing, eye-hand coordination and visualisation components Discussion & Conclusions: Sport specific exercises improved visual skills in rugby players which may provide them with an advantage over their opponents. This study suggests that these training programs and participation in regular on-line EyeDrills sports vision exercises (www.eyedrills.co.za) aimed at improving the athlete-s visual coordination, concentration, focus, hand-eye co-ordination, anticipation and motor response should be incorpotated in the rugby players exercise regime.
Abstract: In this paper an analytical crack propagation scenario
is proposed which assumes that a crack propagates in the tooth root in
both the crack depth direction and the tooth width direction, and
which is more reasonable and realistic for non-uniform load
distribution cases than the other presented scenarios. An analytical
approach is used for quantifying the loss of time-varying gear mesh
stiffness with the presence of crack propagation in the gear tooth root.
The proposed crack propagation scenario can be applied for crack
propagation modelling and monitoring simulation, but further
research is required for comparison and evaluation of all the
presented crack propagation scenarios from the condition monitoring
point of view.
Abstract: The purpose of this research was develop a biological
nutrient removal (BNR) system which has low energy consumption, sludge production, and land usage. These indicate that BNR system could be a alternative of future wastewater treatment in ubiquitous
city(U-city). Organics and nitrogen compounds could be removed by this system so that secondary or tertiary stages of wastewater treatment satisfy their standards. This system was composed of oxic and anoxic
filter filed with PVDC and POM media. Anoxic/oxic filter system operated under empty bed contact time of 4 hours by increasing
recirculation ratio from 0 to 100 %. The system removals of total nitrogen and COD were 76.3% and 93%, respectively. To be observed
internal behavior in this system SCOD, NH3-N, and NO3-N were
conducted and removal shows range of 25~100%, 59~99%, and
70~100%, respectively.
Abstract: Mammographic images and data analysis to
facilitate modelling or computer aided diagnostic (CAD) software development should best be done using a common database that can handle various mammographic image file
formats and relate these to other patient information.
This would optimize the use of the data as both primary
reporting and enhanced information extraction of research data could be performed from the single dataset. One desired
improvement is the integration of DICOM file header information into the database, as an efficient and reliable source of supplementary patient information intrinsically
available in the images.
The purpose of this paper was to design a suitable database to link and integrate different types of image files and gather common information that can be further used for research
purposes. An interface was developed for accessing, adding,
updating, modifying and extracting data from the common
database, enhancing the future possible application of the data in CAD processing.
Technically, future developments envisaged include the creation of an advanced search function to selects image files
based on descriptor combinations. Results can be further used for specific CAD processing and other research. Design of a
user friendly configuration utility for importing of the required fields from the DICOM files must be done.
Abstract: The purpose of this study was to determine the
influence of physical activity and dietary fat intake on Body Mass
Index (BMI) of lecturers within a higher learning institutionalized
setting. The study adopted a Cross-sectional Correlational Design
and included 120 lecturers selected proportionately by simple
random sampling techniques from a population of 600 lecturers. Data
was collected using questionnaires, which had sections including
physical activity checklist adopted from the international physical
activity questionnaire (IPAQ), 24-hour food recall, anthropometric
measurements mainly weight and height. Analysis involved the use
of bivariate correlations and linear regression. A significant inverse
association was registered between BMI and duration (in minutes)
spent doing moderate intense physical activity per day (r=-0.322,
p
Abstract: The multi-agent system for processing Bio-signals
will help the medical practitioners to have a standard examination
procedure stored in web server. Web Servers supporting any standard
Search Engine follow all possible combinations of the search
keywords as an input by the user to a Search Engine. As a result, a
huge number of Web-pages are shown in the Web browser. It also
helps the medical practitioner to interact with the expert in the field
his need in order to make a proper judgment in the diagnosis phase
[3].A web server uses a web server plug in to establish and
maintained the medical practitioner to make a fast analysis. If the
user uses the web server client can get a related data requesting their
search. DB agent, EEG / ECG / EMG agents- user placed with
difficult aspects for updating medical information-s in web server.
Abstract: Interventional cardiologists are at greater risk from
radiation exposure as a result of the procedures they undertake than
most other medical specialists. A study was performed to evaluate
operator dose during interventional cardiology procedures and to
establish methods of operator dose reduction with a radiation
protective device. Different procedure technique and use of
protective tools can explain big difference in the annual equivalent
dose received by the professionals. Strategies to prevent and
monitor radiation exposure, advanced protective shielding and
effective radiation monitoring methods should be applied.
Abstract: This article proposes a new methodology to be used by SMEs (Small and Medium enterprises) to characterize their performance in quality, highlighting weaknesses and area for improvement. The methodology aims to identify the principal causes of quality problems and help to prioritize improvement initiatives. This is a self-assessment methodology that intends to be easy to implement by companies with low maturity level in quality. The methodology is organized in six different steps which includes gathering information about predetermined processes and subprocesses of quality management, defined based on the well-known Juran-s trilogy for quality management (Quality planning, quality control and quality improvement) and, predetermined results categories, defined based on quality concept. A set of tools for data collecting and analysis, such as interviews, flowcharts, process analysis diagrams and Failure Mode and effects Analysis (FMEA) are used. The article also presents the conclusions obtained in the application of the methodology in two cases studies.
Abstract: Monitoring lightning electromagnetic pulses (sferics)
and other terrestrial as well as extraterrestrial transient radiation signals
is of considerable interest for practical and theoretical purposes
in astro- and geophysics as well as meteorology. Managing a continuous
flow of data, automisation of the detection and classification
process is important. Features based on a combination of wavelet and
statistical methods proved efficient for analysis and characterisation
of transients and as input into a radial basis function network that is
trained to discriminate transients from pulse like to wave like.
Abstract: In this paper, we apply the PQ theory with shunt active power filter in an unbalanced and distorted power system voltage to compensate the perturbations generated by non linear load. The power factor is also improved in the current source. The PLL system is used to extract the fundamental component of the even sequence under conditions mentioned of the power system voltage.
Abstract: International markets driven forces are changing
continuously, therefore companies need to gain a competitive edge in
such markets. Improving the company's products, processes and
practices is no longer auxiliary. Lean production is a production
management philosophy that consolidates work tasks with minimum
waste resulting in improved productivity. Lean production practices
can be mapped into many production areas. One of these is
Manufacturing Equipment and Technology (MET). Many lean
production practices can be implemented in MET, namely, specific
equipment configurations, total preventive maintenance, visual
control, new equipment/ technologies, production process
reengineering and shared vision of perfection.The purpose of this
paper is to investigate the implementation level of these six practices
in Jordanian industries. To achieve that a questionnaire survey has
been designed according to five-point Likert scale. The questionnaire
is validated through pilot study and through experts review. A sample
of 350 Jordanian companies were surveyed, the response rate was
83%. The respondents were asked to rate the extent of
implementation for each of practices. A relationship conceptual
model is developed, hypotheses are proposed, and consequently the
essential statistical analyses are then performed. An assessment tool
that enables management to monitor the progress and the
effectiveness of lean practices implementation is designed and
presented. Consequently, the results show that the average
implementation level of lean practices in MET is 77%, Jordanian
companies are implementing successfully the considered lean
production practices, and the presented model has Cronbach-s alpha
value of 0.87 which is good evidence on model consistency and
results validation.
Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.