Abstract: In this study, a comparison of two control methods,
Proportional Control (PC) and Fuzzy Logic Control (FLC), which
have been used to develop an ideal thermoelectric renal hypothermia
system in order to use in renal surgery, has been carried out. Since
the most important issues in long-lasting parenchymatous renal
surgery are to provide an operation medium free of blood and to
prevent renal dysfunction in the postoperative period, control of the
temperature has become very important in renal surgery. The final
product is seriously affected from the changes in temperature,
therefore, it is necessary to reach some desired temperature points
quickly and avoid large overshoot. PIC16F877 microcontroller has
been used as controller for both of these two methods. Each control
method can simply ensure extra renal hypothermia in the targeted
way. But investigation of advantages and disadvantages of every
control method to each other is aimed and carried out by the
experimental implementations. Shortly, investigation of the most
appropriate method to use for development of system and that can be
applied to people safely in the future, has been performed. In this
sense, experimental results show that fuzzy logic control gives out
more reliable responses and efficient performance.
Abstract: Determining depth of anesthesia is a challenging problem
in the context of biomedical signal processing. Various methods
have been suggested to determine a quantitative index as depth of
anesthesia, but most of these methods suffer from high sensitivity
during the surgery. A novel method based on energy scattering of
samples in the wavelet domain is suggested to represent the basic
content of electroencephalogram (EEG) signal. In this method, first
EEG signal is decomposed into different sub-bands, then samples
are squared and energy of samples sequence is constructed through
each scale and time, which is normalized and finally entropy of the
resulted sequences is suggested as a reliable index. Empirical Results
showed that applying the proposed method to the EEG signals can
classify the awake, moderate and deep anesthesia states similar to
BIS.
Abstract: A registration framework for image-guided robotic
surgery is proposed for three emergency neurosurgical procedures,
namely Intracranial Pressure (ICP) Monitoring, External Ventricular
Drainage (EVD) and evacuation of a Chronic Subdural Haematoma
(CSDH). The registration paradigm uses CT and white light as
modalities. This paper presents two simulation studies for a
preliminary evaluation of the registration protocol: (1) The loci of the
Target Registration Error (TRE) in the patient-s axial, coronal and
sagittal views were simulated based on a Fiducial Localisation Error
(FLE) of 5 mm and (2) Simulation of the actual framework using
projected views from a surface rendered CT model to represent white
light images of the patient. Craniofacial features were employed as
the registration basis to map the CT space onto the simulated
intraoperative space. Photogrammetry experiments on an artificial
skull were also performed to benchmark the results obtained from the
second simulation. The results of both simulations show that the
proposed protocol can provide a 5mm accuracy for these
neurosurgical procedures.
Abstract: Human amniotic membrane (HAM) is a useful
biological material for the reconstruction of damaged ocular surface.
The processing and preservation of HAM is critical to prevent the
patients undergoing amniotic membrane transplant (AMT) from cross
infections. For HAM preparation human placenta is obtained after an
elective cesarean delivery. Before collection, the donor is screened
for seronegativity of HCV, Hbs Ag, HIV and Syphilis. After
collection, placenta is washed in balanced salt solution (BSS) in
sterile environment. Amniotic membrane is then separated from the
placenta as well as chorion while keeping the preparation in BSS.
Scrapping of HAM is then carried out manually until all the debris is
removed and clear transparent membrane is acquired. Nitrocellulose
membrane filters are then placed on the stromal side of HAM, cut
around the edges with little membrane folded towards other side
making it easy to separate during surgery. HAM is finally stored in
solution of glycerine and Dulbecco-s Modified Eagle Medium
(DMEM) in 1:1 ratio containing antibiotics. The capped borosil vials
containing HAM are kept at -80°C until use. This vial is thawed to
room temperature and opened under sterile operation theatre
conditions at the time of surgery.
Abstract: A retrospective study was undertaken to record the
occurrence and pattern of fractures in small animals (dogs and cats)
from year 2005 to 2010. A total of 650 cases were presented in small
animal surgery unit out of which of 116 (dogs and cats) were
presented with history of fractures of different bones. A total of
17.8% (116/650) cases were of fractures which constituted dogs 67%
while cats were 23%. The majority of animals were intact. Trauma in
the form of road side accident was the principal cause of fractures in
dogs whereas as in cats it was fall from height. The ages of the
fractured dog ranged from 4 months to 12 years whereas in cat it was
from 4 weeks to 10 years. The femoral fractures represented 37.5%
and 25% respectively in dogs and cats. Diaphysis, distal metaphyseal
and supracondylar fractures were the most affected sites in dog and
cats. Tibial fracture in dogs and cats represented 21.5% and 10%
while humoral fractures were 7.9% and 14% in dogs and cats
respectively. Humoral condyler fractures were most commonly seen
in puppies aged 4 to 6 months. Fractured radius-ulna incidence was
19% and 14% in dogs and cats respectively. Other fractures recorded
were of lumbar vertebrae, mandible and metacarpals etc. The
management comprised of external and internal fixation in both the
species. The most common internal fixation technique employed was
Intramedullary fixation in long followed by other methods like stack
or cross pinning, wiring etc as per findings in the cases. The cast
bandage was used majorly as mean for external coaptation. The
paper discusses the outcome of the case as per the technique
employed.
Abstract: One of the major disadvantages of the minimally
invasive surgery (MIS) is the lack of tactile feedback to the surgeon.
In order to identify and avoid any damage to the grasped complex
tissue by endoscopic graspers, it is important to measure the local
softness of tissue during MIS. One way to display the measured
softness to the surgeon is a graphical method. In this paper, a new
tactile sensor has been reported. The tactile sensor consists of an
array of four softness sensors, which are integrated into the jaws of a
modified commercial endoscopic grasper. Each individual softness
sensor consists of two piezoelectric polymer Polyvinylidene Fluoride
(PVDF) films, which are positioned below a rigid and a compliant
cylinder. The compliant cylinder is fabricated using a micro molding
technique. The combination of output voltages from PVDF films is
used to determine the softness of the grasped object. The theoretical
analysis of the sensor is also presented.
A method has been developed with the aim of reproducing the
tactile softness to the surgeon by using a graphical method. In this
approach, the proposed system, including the interfacing and the data
acquisition card, receives signals from the array of softness sensors.
After the signals are processed, the tactile information is displayed
by means of a color coding method. It is shown that the degrees of
softness of the grasped objects/tissues can be visually differentiated
and displayed on a monitor.
Abstract: The Ramon preparation is received from a plant; it is destined for external treatment of inflammations in post-surgery period. The Ramon is a biogenic immune stimulator accelerating metabolism, contributing to improvement of blood indexes, having general tonic, anti-inflammatory and bactericidal effect.
Abstract: Medical applications are among the most impactful
areas of microrobotics. The ultimate goal of medical microrobots is
to reach currently inaccessible areas of the human body and carry out
a host of complex operations such as minimally invasive surgery
(MIS), highly localized drug delivery, and screening for diseases at
their very early stages. Miniature, safe and efficient propulsion
systems hold the key to maturing this technology but they pose
significant challenges. A new type of propulsion developed recently,
uses multi-flagella architecture inspired by the motility mechanism of
prokaryotic microorganisms. There is a lack of efficient methods for
designing this type of propulsion system. The goal of this paper is to
overcome the lack and this way, a numerical strategy is proposed to
design multi-flagella propulsion systems. The strategy is based on the
implementation of the regularized stokeslet and rotlet theory, RFT
theory and new approach of “local corrected velocity". The effects of
shape parameters and angular velocities of each flagellum on overall
flow field and on the robot net forces and moments are considered.
Then a multi-layer perceptron artificial neural network is designed
and employed to adjust the angular velocities of the motors for
propulsion control. The proposed method applied successfully on a
sample configuration and useful demonstrative results is obtained.
Abstract: Heat pipes are two-phase heat transfer devices with
high effective thermal conductivity. Due to the high heat transport
capacity, heat exchanger with heat pipes has become much smaller
than traditional heat exchangers in handling high heat fluxes. With
the working fluid in a heat pipe, heat can be absorbed on the
evaporator region and transported to the condenser region where the
vapour condenses releasing the heat to the cooling media. Heat pipe
technology has found increasing applications in enhancing the
thermal performance of heat exchangers in microelectranics, energy
saving in HVAC systems for operating rooms,surgery centers, hotels,
cleanrooms etc, temperature regulation systems for the human body
and other industrial sectors. Development activity in heat pipe and
thermosyphon technology in asia in recent years is surveyed. Some
new results obtained in Australia and other countries are also
included.
Abstract: Having considered tactile sensing and palpation of a
surgeon in order to detect kidney stone during open surgery; we
present the 2D model of nephrolithiasis (two dimensional model of
kidney containing a simulated stone). The effects of stone existence
that appear on the surface of kidney (because of exerting mechanical
load) are determined. Using Finite element method, it is illustrated
that the created stress patterns on the surface of kidney and stress
graphs not only show existence of stone inside kidney, but also show
its exact location.
Abstract: Interactive web-based computer simulations are
needed by the medical community to replicate the experience of
surgical procedures as closely and realistically as possible without
the need to practice on corpses, animals and/or plastic models. In this
paper, we offer a review on current state of the research on
simulations of surgical threads, identify future needs and present our
proposed plans to meet them. Our goal is to create a physics-based
simulator, which will predict the behavior of surgical thread when
subjected to conditions commonly encountered during surgery. To
that end, we will i) develop three dimensional finite element models
based on the Cosserat theory of elasticity ii) test and feedback results
with the medical community and iii) develop a web-based user
interface to run/command our simulator and visualize the results. The
impacts of our research are that i) it will contribute to the
development of a new generation of training for medical school
students and ii) the simulator will be useful to expert surgeons in
developing new, better and less risky procedures.
Abstract: Within dental-guided surgery, there has been a lack
of analytical methods for optimizing the treatment of the
rehabilitation concepts regarding geometrical variation. The purpose
of this study is to find the source of the greatest geometrical variation
contributor and sensitivity contributor with the help of virtual
variation simulation of a dental drill- and implant-guided surgery
process using a methodical approach. It is believed that lower
geometrical variation will lead to better patient security and higher
quality of dental drill- and implant-guided surgeries. It was found
that the origin of the greatest contributor to the most variation, and
hence where the foci should be set, in order to minimize geometrical
variation was in the assembly category (surgery). This was also the
category that was the most sensitive for geometrical variation.
Abstract: Young patients suffering from Cerebral Palsy are
facing difficult choices concerning heavy surgeries. Diagnosis settled
by surgeons can be complex and on the other hand decision for
patient about getting or not such a surgery involves important
reflection effort. Proposed software combining prediction for
surgeries and post surgery kinematic values, and from 3D model
representing the patient is an innovative tool helpful for both patients
and medicine professionals. Beginning with analysis and
classification of kinematics values from Data Base extracted from
gait analysis in 3 separated clusters, it is possible to determine close
similarity between patients. Prediction surgery best adapted to
improve a patient gait is then determined by operating a suitable
preconditioned neural network. Finally, patient 3D modeling based
on kinematic values analysis, is animated thanks to post surgery
kinematic vectors characterizing the closest patient selected from
patients clustering.
Abstract: This paper presents design and characterization of a
microaccelerometer designated for integration into cataract surgical
probe to detect hardness of different eye tissues during cataract
surgery. Soft posterior lens capsule of eye can be easily damaged in
comparison with hard opaque lens since the surgeon can not see
directly behind cutting needle during the surgery. Presence of
microsensor helps the surgeon to avoid rupturing posterior lens
capsule which if occurs leads to severe complications such as
glaucoma, infection, or even blindness. The microsensor having
overall dimensions of 480 μm x 395 μm is able to deliver significant
capacitance variations during encountered vibration situations which
makes it capable to distinguish between different types of tissue.
Integration of electronic components on chip ensures high level of
reliability and noise immunity while minimizes space and power
requirements. Physical characteristics and results on performance
testing, proves integration of microsensor as an effective tool to aid
the surgeon during this procedure.
Abstract: This study retrospectively investigated the significance of whole body CT (WCT) for patients with sepsis. A medical chart review was retrospectively performed for all patients with systemic inflammatory response syndrome that were treated initially between April 2011 and March 2012. The subjects were divided into a WCT group that underwent WCT on arrival and a control group. Results of this study suggested that WCT for sepsis was useful for elderly patients whose chief complaint or physiological findings could not suggest the anatomical site of infection, to determine the infectious focus and indications/method for surgery, to diagnose the basic diseases associated with opportunistic infections and to evaluate complicated diseases
Abstract: A new and cost effective robotic device was designed
for remote tele surgery using dual tone multi frequency technology
(DTMF). Tele system with Dual Tone Multiple Frequency has a large
capability in sending and receiving of data in hardware and software.
The robot consists of DC motors for arm movements and it is
controlled manually through a mobile phone through DTMF
Technology. The system enables the surgeon from base station to
send commands through mobile phone to the patient’s robotic system
which includes two robotic arms that translate the input into actual
instrument manipulation. A mobile phone attached to the
microcontroller 8051 which can activate robot through relays. The
Remote robot-assisted tele surgery eliminates geographic constraints
for getting surgical expertise where it is needed and allows an expert
surgeon to teach or proctor the performance of surgical technique by
real-time intervention.
Abstract: This work concerns the evolution and the maintenance
of an ontological resource in relation with the evolution of the corpus
of texts from which it had been built.
The knowledge forming a text corpus, especially in dynamic domains,
is in continuous evolution. When a change in the corpus occurs, the
domain ontology must evolve accordingly. Most methods manage
ontology evolution independently from the corpus from which it is
built; in addition, they treat evolution just as a process of knowledge
addition, not considering other knowledge changes. We propose a
methodology for managing an evolving ontology from a text corpus
that evolves over time, while preserving the consistency and the
persistence of this ontology.
Our methodology is based on the changes made on the corpus to
reflect the evolution of the considered domain - augmented surgery
in our case. In this context, the results of text mining techniques,
as well as the ARCHONTE method slightly modified, are used to
support the evolution process.
Abstract: Female breast cancer is the second in frequency after cervical cancer. Surgery is the most common treatment for breast cancer, followed by chemotherapy as a treatment of choice. Although effective, it causes serious side effects. Controlled-release drug delivery is an alternative method to improve the efficacy and safety of the treatment. It can release the dosage of drug between the minimum effect concentration (MEC) and minimum toxic concentration (MTC) within tumor tissue and reduce the damage of normal tissue and the side effect. Because an in vivo experiment of this system can be time-consuming and labor-intensive, a mathematical model is desired to study the effects of important parameters before the experiments are performed. Here, we describe a 3D mathematical model to predict the release of doxorubicin from pluronic gel to treat human breast cancer. This model can, ultimately, be used to effectively design the in vivo experiments.
Abstract: Magnesium is used implant material potentially for
non-toxicity to the human body. Due to the excellent
bio-compatibility, Mg alloys is applied to implants avoiding removal
second surgery. However, it is found commercial magnesium alloys
including aluminum has low corrosion resistance, resulting
subcutaneous gas bubbles and consequently the approach as
permanent bio-materials. Generally, Aluminum is known to pollution
substance, and it raises toxicity to nervous system. Therefore
especially Mg-35Zn-3Ca alloy is prepared for new biodegradable
materials in this study. And the pulsed power is used in
constant-current mode of DC power kinds of anodization. Based on
the aforementioned study, it examines corrosion resistance and
biocompatibility by effect of current and frequency variation. The
surface properties and thickness were compared using scanning
electronic microscopy. Corrosion resistance was assessed via
potentiodynamic polarization and the effect of oxide layer on the body
was assessed cell viability. Anodized Mg-35Zn-3Ca alloy has good
biocompatibility in vitro by current and frequency variation.
Abstract: Deaths from cardiovascular diseases have decreased substantially over the past two decades, largely as a result of advances in acute care and cardiac surgery. These developments have produced a growing population of patients who have survived a myocardial infarction. These patients need to be continuously monitored so that the initiation of treatment can be given within the crucial golden hour. The available conventional methods of monitoring mostly perform offline analysis and restrict the mobility of these patients within a hospital or room. Hence the aim of this paper is to design a Portable Cardiac Telemedicine System to aid the patients to regain their independence and return to an active work schedule, there by improving the psychological well being. The portable telemedicine system consists of a Wearable ECG Transmitter (WET) and a slightly modified mobile phone, which has an inbuilt ECG analyzer. The WET is placed on the body of the patient that continuously acquires the ECG signals from the high-risk cardiac patients who can move around anywhere. This WET transmits the ECG to the patient-s Bluetooth enabled mobile phone using blue tooth technology. The ECG analyzer inbuilt in the mobile phone continuously analyzes the heartbeats derived from the received ECG signals. In case of any panic condition, the mobile phone alerts the patients care taker by an SMS and initiates the transmission of a sample ECG signal to the doctor, via the mobile network.