Abstract: It is the patient compliance and stability in
combination with controlled drug delivery and biocompatibility that
forms the core feature in present research and development of
sustained biodegradable patch formulation intended for wound
healing. The aim was to impart sustained degradation, sterile
formulation, significant folding endurance, elasticity,
biodegradability, bio-acceptability and strength. The optimized
formulation comprised of polymers including Hydroxypropyl methyl
cellulose, Ethylcellulose, and Gelatin, and Citric Acid PEG Citric
acid (CPEGC) triblock dendrimers and active Curcumin. Polymeric
mixture dissolved in geometric order in suitable medium through
continuous stirring under ambient conditions. With continued stirring
Curcumin was added with aid of DCM and Methanol in optimized
ratio to get homogenous dispersion. The dispersion was sonicated
with optimum frequency and for given time and later casted to form a
patch form. All steps were carried out under strict aseptic conditions.
The formulations obtained in the acceptable working range were
decided based on thickness, uniformity of drug content, smooth
texture and flexibility and brittleness. The patch kept on stability
using butter paper in sterile pack displayed folding endurance in
range of 20 to 23 times without any evidence of crack in an
optimized formulation at room temperature (RT) (24 ± 2°C). The
patch displayed acceptable parameters after stability study conducted
in refrigerated conditions (8±0.2°C) and at RT (24 ± 2°C) up to 90
days. Further, no significant changes were observed in critical
parameters such as elasticity, biodegradability, drug release and drug
content during stability study conducted at RT 24±2°C for 45 and 90
days. The drug content was in range 95 to 102%, moisture content
didn’t exceeded 19.2% and patch passed the content uniformity test.
Percentage cumulative drug release was found to be 80% in 12h and
matched the biodegradation rate as drug release with correlation
factor R2>0.9. The biodegradable patch based formulation developed
shows promising results in terms of stability and release profiles.
Abstract: While choosing insulating oil, characteristic features
such as thermal cooling, endurance, efficiency and being
environment-friendly should be considered. Mineral oils are referred
as petroleum-based oil. In this study, vegetable oils investigated as an
alternative insulating liquid to mineral oil. Dissipation factor,
breakdown voltage, relative dielectric constant and resistivity
changes with the frequency and voltage of mineral, rapeseed and nut
oils were measured. Experimental studies were performed according
to ASTM D924 and IEC 60156 standards.
Abstract: Unmanned Aircraft Systems (UAS) become
indispensable parts of modern airpower as force multiplier. One of
the main advantages of UAS is long endurance. UAS have to take
extra payloads to accomplish different missions but these payloads
decrease endurance of aircraft because of increasing drag. There are
continuing researches to increase the capability of UAS. There are
some vertical thermal air currents, which can cause climb and
increase endurance, in nature. Birds and gliders use thermals to gain
altitude with no effort. UAS have wide wings which can use
thermals like birds and gliders. Thermal regions, which is area of
2000-3000 meter (1 NM), exist all around the world. It is natural and
infinite source. This study analyses if thermal regions can be adopted
and implemented as an assistant tool for UAS route planning. First
and second part of study will contain information about the thermal
regions and current applications about UAS in aviation and climbing
performance with a real example. Continuing parts will analyze the
contribution of thermal regions to UAS endurance. Contribution is
important because planning declaration of UAS navigation rules will
be in 2015.
Abstract: Various biomass based resources, which can be used
as an extender, or a complete substitute of diesel fuel may have very
significant role in the development of agriculture, industrial and
transport sectors in the energy crisis. Use of Karanja oil methyl ester
biodiesel in a CI DI engine was found highly compatible with engine
performance along with lower exhaust emission as compared to
diesel fuel but with slightly higher NOx emission and low wear
characteristics. The combustion related properties of vegetable oils
are somewhat similar to diesel oil. Neat vegetable oils or their blends
with diesel, however, pose various long-term problems in
compression ignition engines. These undesirable features of
vegetable oils are because of their inherent properties like high
viscosity, low volatility, and polyunsaturated character. Pongamia
methyl ester (PME) was prepared by transesterification process using
methanol for long term engine operations. The physical and
combustion-related properties of the fuels thus developed were found
to be closer to that of the diesel. A neat biodiesel (PME) was selected
as a fuel for the tribological study of biofuels.
Two similar new engines were completely disassembled and
subjected to dimensioning of various vital moving parts and then
subjected to long-term endurance tests on neat biodiesel and diesel
respectively. After completion of the test, both the engines were
again disassembled for physical inspection and wear measurement of
various vital parts. The lubricating oil samples drawn from both
engines were subjected to atomic absorption spectroscopy (AAS) for
measurement of various wear metal traces present. The additional
lubricating property of biodiesel fuel due to higher viscosity as
compared to diesel fuel resulted in lower wear of moving parts and
thus improved the engine durability with a bio-diesel fuel. Results
reported from AAS tests confirmed substantially lower wear and thus
improved life for biodiesel operated engines.
Abstract: Hand grip strength has been utilized as an indicator to evaluate the motor ability of hands, responsible for performing multiple body functions. It is, however, difficult to evaluate other factors (other than hand muscular strength) utilizing the hand grip strength only. In this study, we analyzed the motor ability of hands using EMG and the hand grip strength, simultaneously in order to evaluate concentration, muscular strength reaction time, instantaneous muscular strength change, and agility in response to visual reaction. In results, the average time (and their standard deviations) of muscular strength reaction EMG signal and hand grip strength was found to be 209.6 ± 56.2 ms and 354.3 ± 54.6 ms, respectively. In addition, the onset time which represents acceleration time to reach 90% of maximum hand grip strength, was 382.9 ± 129.9 ms.
Abstract: Background: Occupational standing is associated with low back pain (LBP) development. Yet, trunk and gluteus-medius muscles’ fatigability has not been extensively studied during occupational standing. This study examined and correlated the rectus abdominus (RA), erector-spinae (ES), external oblique (EO), and gluteus-medius (GM) muscles’ fatigability on both sides while standing in a confined area for 30min Methods: Median frequency EMG data were collected from 15 female clinical instructors with chronic LBP (group A) and 15 asymptomatic controls (group B) (mean age 29.53±2.4 vs 29.07±2.4years, weight 63.6±7 vs 60±7.8kg, and height 162.73±4 vs 162.8±6cm respectively) using a spectrum analysis program. Data were collected in the first and last 5min of the standing task. Results: Using Mixed three-way ANOVA, group A showed significantly (p
Abstract: The aim of this study was to evaluate the effect of preexercise glycerol hyperhydration on endurance performance in a heat chamber designed to simulate the World Championship Distance (WCD) duathlon (10km run, 40km ride, 5 km run). Duathlons are often performed in hot and humid conditions and as a result hydration is a major issue. Glycerol enhances the body’s capacity for fluid retention by inducing hyperhydration, which is theorized to improve thermoregulatory and cardiovascular responses, and thereby improve performance. Six well-trained athletes completed the testing protocol in a heat chamber at the La Trobe University Exercise Physiology Laboratory. Each testing session was approximately 4.5 hours in duration (2 hours of pre-exercise glycerol hyper-hydration followed by approximately 2.5 hours of exercise). The results showed an increased water retention pre-exercise and an improved overall performance of 2.04% was achieved by subjects ingesting the glycerol solution.
Abstract: Gliding during night without electric power is an efficient method to enhance endurance performance of solar aircrafts. The properties of maximum gliding endurance path are studied in this paper. The problem is formulated as an optimization problem about maximum endurance can be sustained by certain potential energy storage with dynamic equations and aerodynamic parameter constrains. The optimal gliding path is generated based on gauss pseudo-spectral method. In order to analyse relationship between altitude, velocity of solar UAVs and its endurance performance, the lift coefficient in interval of [0.4, 1.2] and flight envelopes between 0~30km are investigated. Results show that broad range of lift coefficient can improve solar aircrafts- long endurance performance, and it is possible for a solar aircraft to achieve the aim of long endurance during whole night just by potential energy storage.
Abstract: Shape optimization of the airfoil with high aspect ratio
of long endurance unmanned aerial vehicle (UAV) is performed by the
multi-objective optimization technology coupled with computational
fluid dynamics (CFD). For predicting the aerodynamic characteristics
around the airfoil the high-fidelity Navier-Stokes solver is employed
and SMOGA (Simple Multi-Objective Genetic Algorithm), which is
developed by authors, is used for solving the multi-objective
optimization problem. To obtain the optimal solutions of the design
variable (i.e., sectional airfoil profile, wing taper ratio and sweep) for
high performance of UAVs, both the lift and lift-to-drag ratio are
maximized whereas the pitching moment should be minimized,
simultaneously. It is found that the lift force and lift-to-drag ratio are
linearly dependent and a unique and dominant solution are existed.
However, a trade-off phenomenon is observed between the lift-to-drag
ratio and pitching moment. As the result of optimization, sixty-five
(65) non-dominated Pareto individuals at the cutting edge of design
spaces that is decided by airfoil shapes can be obtained.
Abstract: MRAM technology provides a combination of fast
access time, non-volatility, data retention and endurance. While a
growing interest is given to two-terminal Magnetic Tunnel Junctions
(MTJ) based on Spin-Transfer Torque (STT) switching as the
potential candidate for a universal memory, its reliability is
dramatically decreased because of the common writing/reading path.
Three-terminal MTJ based on Spin-Orbit Torque (SOT) approach
revitalizes the hope of an ideal MRAM. It can overcome the
reliability barrier encountered in current two-terminal MTJs by
separating the reading and the writing path. In this paper, we study
two possible writing schemes for the SOT-MTJ device based on
recently fabricated samples. While the first is based on precessional
switching, the second requires the presence of permanent magnetic
field. Based on an accurate Verilog-A model, we simulate the two
writing techniques and we highlight advantages and drawbacks of
each one. Using the second technique, pioneering logic circuits based
on the three-terminal architecture of the SOT-MTJ described in this
work are under development with preliminary attractive results.
Abstract: Scalability poses a severe threat to the existing
DRAM technology. The capacitors that are used for storing and
sensing charge in DRAM are generally not scaled beyond 42nm.
This is because; the capacitors must be sufficiently large for reliable
sensing and charge storage mechanism. This leaves DRAM memory
scaling in jeopardy, as charge sensing and storage mechanisms
become extremely difficult. In this paper we provide an overview of
the potential and the possibilities of using Phase Change Memory
(PCM) as an alternative for the existing DRAM technology. The
main challenges that we encounter in using PCM are, the limited
endurance, high access latencies, and higher dynamic energy
consumption than that of the conventional DRAM. We then provide
an overview of various methods, which can be employed to
overcome these drawbacks. Hybrid memories involving both PCM
and DRAM can be used, to achieve good tradeoffs in access latency
and storage density. We conclude by presenting, the results of these
methods that makes PCM a potential replacement for the current
DRAM technology.
Abstract: This article provides partial evaluation index and its
standard of sports aerobics, including the following 12 indexes: health
vitality, coordination, flexibility, accuracy, pace, endurance, elasticity,
self-confidence, form, control, uniformity and musicality. The
three-layer BP artificial neural network model including input layer,
hidden layer and output layer is established. The result shows that the
model can well reflect the non-linear relationship between the
performance of 12 indexes and the overall performance. The predicted
value of each sample is very close to the true value, with a relative
error fluctuating around of 5%, and the network training is successful.
It shows that BP network has high prediction accuracy and good
generalization capacity if being applied in sports aerobics performance
evaluation after effective training.
Abstract: The malfunction of thermal protection system (TPS) caused by aerodynamic heating is a latent trouble to aircraft structure safety. Accurately predicting the structure temperature field is quite important for the TPS design of hypersonic vehicle. Since Thornton’s work in 1988, the coupled method of aerodynamic heating and heat transfer has developed rapidly. However, little attention has been paid to the influence of structural deformation on aerodynamic heating and structural temperature field. In the flight, especially the long-endurance flight, the structural deformation, caused by the aerodynamic heating and temperature rise, has a direct impact on the aerodynamic heating and structural temperature field. Thus, the coupled interaction cannot be neglected. In this paper, based on the method of static aero-thermo-elasticity, considering the influence of aero-thermo-elasticity deformation, the aerodynamic heating and heat transfer coupled results of hypersonic vehicle wing model were calculated. The results show that, for the low-curvature region, such as fuselage or center-section wing, structure deformation has little effect on temperature field. However, for the stagnation region with high curvature, the coupled effect is not negligible. Thus, it is quite important for the structure temperature prediction to take into account the effect of elastic deformation. This work has laid a solid foundation for improving the prediction accuracy of the temperature distribution of aircraft structures and the evaluation capacity of structural performance.
Abstract: Background: Tissue Doppler Echocardiography
(TDE) assesses diastolic function more accurately than routine pulse
Doppler echo. Assessment of the effects of dynamic and static
exercises on the heart by using TDE can provides new information
about the athlete-s heart syndrome. Methods: This study was
conducted on 20 elite wrestlers, 14 endurance runners at national
level and 21 non-athletes as the control group. Participants underwent
two-dimensional echocardiography, standard Doppler and TDE.
Results: Wrestlers had the highest left ventricular mass index, enddiastolic
inter-ventricular septum thickness and left ventricular
Posterior wall thickness. Runners had the highest Left ventricular
end-diastolic volume, LV ejection fraction, stroke volume and
cardiac output. In TDE, the early diastolic velocity of mitral annulus
to the late diastolic velocity ratio in athletic groups was greater than
the controls with no significant difference. Conclusion: In spite of
cardiac morphological changes in athletes, TDE shows that cardiac
diastolic function won-t be adversely affected.
Abstract: We investigated the response of testosterone (T),
growth hormone (GH), cortisol (C), steroid hormone binding
globulin (SHBG), insulin-like growth factor (IGF-1), insulin-like
growth factor binding protein-3 (IGFBP-3), and some anaboliccatabolic
indexes, i.e.: T/C, T/SHBG, and IGF-1/IGFBP-3 to
maximal exercise in endurance-trained athletes (TREN) and
untrained subjects (CG). The baseline concentration of IGF-1 was
higher in athletes (TREN) when compared to the CG (p
Abstract: Resistive switching of aluminum nitride (AlNx) thin film was demonstrated in a TaN/AlNx/TiN memory cell that was prepared by sputter deposition techniques. The memory cell showed bipolar switching of resistance between +3.5 V and –3.5 V. The resistance ratio of high resistance state (HRS) to low resistance state (HRS), RHRS/RLRS, was about 2 over 100 cycles of endurance test. Both the LRS and HRS of the memory cell exhibited ohmic conduction at low voltages and Poole-Frenkel emission at high voltages. The electrical conduction in the TaN/AlNx/TiN memory cell was possibly attributed to the interactions between charges and defects in the AlNx film.
Abstract: The aim of this study is to describe the associations
between the temperamental traits and the narrative emotional
expression. The Temperament Questionnaire was used: The FCB-TI
of Zawadzki & Strelau. A sample of 85 persons described three
emotional situations: love. hate, and anxiety. This study analyzes the
verbal form of expression by means of a written account of
emotions. The relationship between the narratives of love, hate and
anxiety and temperament characteristics were studied. Results
indicate that vigorousness (VI), perseverance (PE), sensory
sensitivity (SS), emotional reactivity (ER), endurance (EN) and
activeness (AC) have a significant impact on the emotional
expression in narratives. The temperamental traits are linked to the
form of emotional language. It means that temperament has an
impact on cognitive representations of emotions.
Abstract: This study was conducted to determine the
objectivity, reliability and validity of the 90º push-ups test protocol
among male and female students of Sports Science Program, Faculty
of Sports Science and Coaching Sultan Idris University of Education.
Samples (n = 300), consisted of males (n = 168) and females (n =
132) students were randomly selected for this study. Researchers
tested the 90º push-ups on the sample twice in a single trial, test and
re-test protocol in the bench press test. Pearson-Product Moment
Correlation method's was used to determine the value of objectivity,
reliability and validity testing. The findings showed that the 900 pushups
test protocol showed high consistency between the two testers
with a value of r = .99. Likewise, The reliability value between test
and re-test for the 90º push-ups test for the male (r=.93) and female
(r=.93) students was also high. The results showed a correlation
between 90º push-ups test and bench press test for boys was r = .64
and girls was r = .28. This finding indicates that the use of the 90º
push-ups to test muscular strength and endurance in the upper body
of males has a higher validity values than female students.