Abstract: The hydrolysis of lactose using β-galactosidase is one of the most promising biotechnological applications, which has wide range of potential applications in food processing industries. However, due to intracellular location of the yeast enzyme, and expensive extraction methods, the industrial applications of enzymatic hydrolysis processes are being hampered. The use of permeabilization technique can help to overcome the problems associated with enzyme extraction and purification of yeast cells and to develop the economically viable process for the utilization of whole cell biocatalysts in food industries. In the present investigation, standardization of permeabilization process of novel yeast isolate was carried out using a statistical model approach known as Response Surface Methodology (RSM) to achieve maximal b-galactosidase activity. The optimum operating conditions for permeabilization process for optimal β-galactosidase activity obtained by RSM were 1:1 ratio of toluene (25%, v/v) and ethanol (50%, v/v), 25.0 oC temperature and treatment time of 12 min, which displayed enzyme activity of 1.71 IU /mg DW.
Abstract: The proliferation of health data standards today is somewhat overlapping and conflicting, resulting in market confusion and leading to increasing proprietary interests. The government role and support in standardization for health data are thought to be crucial in order to establish credible standards for the next decade, to maximize interoperability across the health sector, and to decrease the risks associated with the implementation of non-standard systems. The normative literature missed out the exploration of the different steps required to be undertaken by the government towards the development of national health data standards. Based on the lessons learned from a qualitative study investigating the different issues to the adoption of health data standards in the major tertiary hospitals in Saudi Arabia and the opinions and feedback from different experts in the areas of data exchange and standards and medical informatics in Saudi Arabia and UK, a list of steps required towards the development of national health data standards was constructed. Main steps are the existence of: a national formal reference for health data standards, an agreed national strategic direction for medical data exchange, a national medical information management plan and a national accreditation body, and more important is the change management at the national and organizational level. The outcome of this study can be used by academics and practitioners to develop the planning of health data standards, and in particular those in developing countries.
Abstract: The conventional assessment of human semen is a
highly subjective assessment, with considerable intra- and interlaboratory
variability. Computer-Assisted Sperm Analysis (CASA)
systems provide a rapid and automated assessment of the sperm
characteristics, together with improved standardization and quality
control. However, the outcome of CASA systems is sensitive to the
method of experimentation. While conventional CASA systems use
digital microscopes with phase-contrast accessories, producing
higher contrast images, we have used raw semen samples (no
staining materials) and a regular light microscope, with a digital
camera directly attached to its eyepiece, to insure cost benefits and
simple assembling of the system. However, since the accurate finding
of sperms in the semen image is the first step in the examination and
analysis of the semen, any error in this step can affect the outcome of
the analysis. This article introduces and explains an algorithm for
finding sperms in low contrast images: First, an image enhancement
algorithm is applied to remove extra particles from the image. Then,
the foreground particles (including sperms and round cells) are
segmented form the background. Finally, based on certain features
and criteria, sperms are separated from other cells.
Abstract: Business Process Reengineering (BPR) is an essential tool before an information system project implementation. Enterprise Resource Planning (ERP) projects definitely require the standardization and fixation of business processes from customer order to shipment. Therefore, ERP implementations are well proven to be coupled with BPR, although the extend and timing of BPR with respect to ERP implementation differ. This study aims at analyzing the effects of BPR on ERP implementation success. Basing on two Turkish ERP implementations in pharmaceutical sector, a comparative study is performed. One of the ERP implementations took place after a BPR implementation, whereas the other implementation was without a prior BPR application. Both implementations have been realized with the same consultant team, the case with prior BPR implementation going live first. The results of the case study reveal that if business processes are not optimized and improved before an ERP implementation, ERP live system would face with disharmony problems of processes and processes automated by ERP. This suggests a definite precedence relationship between BPR and ERP applications
Abstract: International trade involves both large and small firms
engaged in business overseas. Possible drivers that force companies
to enter international markets include increasing competition at the
domestic market, maturing domestic markets, and limited domestic
market opportunities. Technology is an important driving factor in
shaping international marketing strategy as well as in driving force
towards a more global marketplace, especially technology in
communication. It includes telephones, the internet, computer
systems and e-mail. There are three main marketing strategy choices,
namely standardization approach, adaptation approach and middleof-
the-road approach that companies implement to overseas markets.
The decision depends on situations and factors facing the companies
in the international markets. In this paper, the contingency concept is
considered that no single strategy can be effective in all contexts.
The effect of strategy on performance depends on specific situational
variables. Strategic fit is employed to investigate export marketing
strategy adaptation under certain environmental conditions, which in
turn can lead to superior performance.
Abstract: The paper describes a knowledge based system for
analysis of microscopic wear particles. Wear particles contained in
lubricating oil carry important information concerning machine
condition, in particular the state of wear. Experts (Tribologists) in the
field extract this information to monitor the operation of the machine
and ensure safety, efficiency, quality, productivity, and economy of
operation. This procedure is not always objective and it can also be
expensive. The aim is to classify these particles according to their
morphological attributes of size, shape, edge detail, thickness ratio,
color, and texture, and by using this classification thereby predict
wear failure modes in engines and other machinery. The attribute
knowledge links human expertise to the devised Knowledge Based
Wear Particle Analysis System (KBWPAS). The system provides an
automated and systematic approach to wear particle identification
which is linked directly to wear processes and modes that occur in
machinery. This brings consistency in wear judgment prediction
which leads to standardization and also less dependence on
Tribologists.
Abstract: In today-s economy plant engineering faces many
challenges. For instance the intensifying competition in this business
is leading to cost competition and needs for a shorter time-to-market.
To remain competitive companies need to make their businesses
more profitable by implementing improvement programs such as
standardization projects. But they have difficulties to tap their full
economic potential for various reasons. One of them is non-holistic
planning and implementation of standardization projects. This paper
describes a new conceptual framework - the layer-model. The model
combines and expands existing proven approaches in order to
improve design, implementation and management of standardization
projects. Based on a holistic approach it helps to systematically
analyze the effects of standardization projects on different business
layers and enables companies to better seize the opportunities offered
by standardization.
Abstract: As German companies roll out their standardized
production systems to offshore manufacturing plants, they face the
challenge of implementing them in different cultural environments.
Studies show that the local adaptation is one of the key factors for a
successful implementation. Thus the question arises of where the line
between standardization and adaptation can be drawn. To answer
this question the influence of culture on production systems is
analysed in this paper. The culturally contingent components of
production systems are identified. Also the contingency factors are
classified according to their impact on the necessary adaptation
changes and implementation effort. Culturally specific decision
making, coordination, communication and motivation patterns
require one-time changes in organizational and process design. The
attitude towards rules requires more intense coaching and controlling.
Lastly a framework is developed to depict standardization and
adaption needs when transplanting production systems into different
cultural environments.
Abstract: In this paper the FPGA implementations for four
stream ciphers are presented. The two stream ciphers, MUGI and
SNOW 2.0 are recently adopted by the International Organization for
Standardization ISO/IEC 18033-4:2005 standard. The other two
stream ciphers, MICKEY 128 and TRIVIUM have been submitted
and are under consideration for the eSTREAM, the ECRYPT
(European Network of Excellence for Cryptology) Stream Cipher
project. All ciphers were coded using VHDL language. For the
hardware implementation, an FPGA device was used. The proposed
implementations achieve throughputs range from 166 Mbps for
MICKEY 128 to 6080 Mbps for MUGI.
Abstract: This article presents the evolution and technological changes implemented on the full scale simulators developed by the Simulation Department of the Instituto de Investigaciones Eléctricas1 (Mexican Electric Research Institute) and located at different training centers around the Mexican territory, and allows US to know the last updates, basically from the input/output view point, of the current simulators at some facilities of the electrical sector as well as the compatible industry of the electrical manufactures and industries such as Comision Federal de Electricidad (CFE*, The utility Mexican company). Tendencies of these developments and impact within the operators- scope are also presented.
Abstract: The present investigation was aimed to develop methodology for the standardization of Marichyadi Vati and its raw materials. Standardization was carried using systematic Pharmacognostical and physicochemical parameters as per WHO guidelines. The detailed standardization of Marichyadi Vati, it is concluded that there are no major differences prevailed in the quality of marketed products and laboratory samples of Marichyadi Vati. However, market samples showed slightly better amount of Piperine than the laboratory sample by both methods. This is the first attempt to generate complete set of standards required for the Marichyadi Vati.
Abstract: The occurrence of missing values in database is a serious problem for Data Mining tasks, responsible for degrading data quality and accuracy of analyses. In this context, the area has shown a lack of standardization for experiments to treat missing values, introducing difficulties to the evaluation process among different researches due to the absence in the use of common parameters. This paper proposes a testbed intended to facilitate the experiments implementation and provide unbiased parameters using available datasets and suited performance metrics in order to optimize the evaluation and comparison between the state of art missing values treatments.
Abstract: The move towards internationalization of accounting encountered a great boost, when in 2002 EU delegated the IASB to provide the accounting standards to be applied inside its frontiers. Among the incentives of the standardization of accounting on the international level, is the reduction of the cost of capital. Romania made the move towards IFRS before EU, when the country was not yet a member of it. Even if this made Romania a special case, it was scarcely approached. The leak of real data is usually the reason for avoiding. The novelty of this paper is that it offers an insight from the reality of Romanian companies and their view regarding the IFRS. The paper is based on a survey that the authors made among the companies listed on the first two tiers of the Bucharest Stock Exchange (BSE), which are basically, the most important companies in the country.
Abstract: There exists a strong correlation between efficient project management and competitive advantage for organizations. Therefore, organizations are striving to standardize and assess the rigor of their project management processes and capabilities i.e. project management maturity. Researchers and standardization organizations have developed several project management maturity models (PMMMs) to assess project management maturity of the organizations. This study presents a critical evaluation of some of the leading PMMMs against OPM3® in a multitude of ways to look at which PMMM is the most comprehensive model - which could assess most aspects of organizations and also help the organizations in gaining competitive advantage over competitors. After a detailed morphological analysis of the models, it is concluded that OPM3® is the most promising maturity model that can really provide a competitive advantage to the organizations due to its unique approach of assessment and improvement strategies.
Abstract: This research aims to examine the key success factors
for the diffusion of mobile entertainment services in Malaysia. The
drivers and barriers observed in this research include perceived
benefit; concerns pertaining to pricing, product and technological
standardization, privacy and security; as well as influences from
peers and community. An analysis of a Malaysian survey of 384
respondents between 18 to 25 years shows that subscribers placed
greater importance on perceived benefit of mobile entertainment
services compared to other factors. Results of the survey also show
that there are strong positive correlations between all the factors,
with pricing issue–perceived benefit showing the strongest
relationship. This paper aims to provide an extensive study on the
drivers and barriers that could be used to derive architecture for
entertainment service provision to serve as a guide for telcos to
outline suitable approaches in order to encourage mass market
adoption of mobile entertainment services in Malaysia.
Abstract: This paper presents the study of parameters affecting
the environment protection in the printing industry. The paper has
also compared LCA studies performed within the printing industry in
order to identify common practices, limitations, areas for
improvement, and opportunities for standardization. This comparison
is focused on the data sources and methodologies used in the printing
pollutants register. The presented concepts, methodology and results
represent the contribution to the sustainable development
management. Furthermore, the paper analyzes the result of the
quantitative identification of hazardous substances emitted in printing
industry of Novi Sad.
Abstract: Introducing survivability into embedded real-time system (ERTS) can improve the survivability power of the system. This paper mainly discusses about the survivability of ERTS. The first is the survivability origin of ERTS. The second is survivability analysis. According to the definition of survivability based on survivability specification and division of the entire survivability analysis process for ERTS, a survivability analysis profile is presented. The quantitative analysis model of this profile is emphasized and illuminated in detail, the quantifying analysis of system was showed helpful to evaluate system survivability more accurate. The third is platform design of survivability analysis. In terms of the profile, the analysis process is encapsulated and assembled into one platform, on which quantification, standardization and simplification of survivability analysis are all achieved. The fourth is survivability design. According to character of ERTS, strengthened design method is selected to realize system survivability design. Through the analysis of embedded mobile video-on-demand system, intrusion tolerant technology is introduced in whole survivability design.
Abstract: Network layer multicast, i.e. IP multicast, even after
many years of research, development and standardization, is not
deployed in large scale due to both technical (e.g. upgrading of
routers) and political (e.g. policy making and negotiation) issues.
Researchers looked for alternatives and proposed application/overlay
multicast where multicast functions are handled by end hosts, not
network layer routers. Member hosts wishing to receive multicast
data form a multicast delivery tree. The intermediate hosts in the tree
act as routers also, i.e. they forward data to the lower hosts in the
tree. Unlike IP multicast, where a router cannot leave the tree until all
members below it leave, in overlay multicast any member can leave
the tree at any time thus disjoining the tree and disrupting the data
dissemination. All the disrupted hosts have to rejoin the tree. This
characteristic of the overlay multicast causes multicast tree unstable,
data loss and rejoin overhead. In this paper, we propose that each node
sets its leaving time from the tree and sends join request to a number
of nodes in the tree. The nodes in the tree will reject the request if
their leaving time is earlier than the requesting node otherwise they
will accept the request. The node can join at one of the accepting
nodes. This makes the tree more stable as the nodes will join the tree
according to their leaving time, earliest leaving time node being at the
leaf of the tree. Some intermediate nodes may not follow their leaving
time and leave earlier than their leaving time thus disrupting the tree.
For this, we propose a proactive recovery mechanism so that disrupted
nodes can rejoin the tree at predetermined nodes immediately. We
have shown by simulation that there is less overhead when joining
the multicast tree and the recovery time of the disrupted nodes is
much less than the previous works. Keywords
Abstract: This paper argues that a product development exercise
involves in addition to the conventional stages, several decisions
regarding other aspects. These aspects should be addressed
simultaneously in order to develop a product that responds to the
customer needs and that helps realize objectives of the stakeholders
in terms of profitability, market share and the like. We present a
framework that encompasses these different development
dimensions. The framework shows that a product development
methodology such as the Quality Function Deployment (QFD) is the
basic tool which allows definition of the target specifications of a
new product. Creativity is the first dimension that enables the
development exercise to live and end successfully. A number of
group processes need to be followed by the development team in
order to ensure enough creativity and innovation. Secondly,
packaging is considered to be an important extension of the product.
Branding strategies, quality and standardization requirements,
identification technologies, design technologies, production
technologies and costing and pricing are also integral parts to the
development exercise. These dimensions constitute the proposed
framework. The paper also presents a mathematical model used to
calculate the design targets based on the target costing principle. The
framework is used to study a case of a new product development in
the telecommunications services sector.
Abstract: In this paper, a framework for the simplification and
standardization of metaheuristic related parameter-tuning by applying
a four phase methodology, utilizing Design of Experiments and
Artificial Neural Networks, is presented. Metaheuristics are multipurpose
problem solvers that are utilized on computational optimization
problems for which no efficient problem specific algorithm
exist. Their successful application to concrete problems requires the
finding of a good initial parameter setting, which is a tedious and
time consuming task. Recent research reveals the lack of approach
when it comes to this so called parameter-tuning process. In the
majority of publications, researchers do have a weak motivation for
their respective choices, if any. Because initial parameter settings
have a significant impact on the solutions quality, this course of
action could lead to suboptimal experimental results, and thereby
a fraudulent basis for the drawing of conclusions.