Abstract: Vernonia divergens Benth., commonly known as
“Insulin Plant” (Fam: Asteraceae) is a potent sugar killer. Locally the
leaves of the plant, boiled in water are successfully administered to a
large number of diabetic patients. The present study evaluates the
putative anti-diabetic ingredients, isolated from the in vivo and in
vitro grown plantlets of V. divergens for their antimicrobial and
anticancer activities. Sterilized explants of nodal segments were
cultured on MS (Musashige and Skoog, 1962) medium in presence of
different combinations of hormones. Multiple shoots along with
bunch of roots were regenerated at 1mg l-1 BAP and 0.5 mg l-1 NAA.
Micro-plantlets were separated and sub-cultured on the double
strength (2X) of the above combination of hormones leading to
increased length of roots and shoots. These plantlets were
successfully transferred to soil and survived well in nature. The
ethanol extract of plantlets from both in vivo & in vitro sources were
prepared in soxhlet extractor and then concentrated to dryness under
reduced pressure in rotary evaporator. Thus obtainedconcentrated
extracts showed significant inhibitory activity against gram
negative bacteria like Escherichia coli and Pseudomonas
aeruginosa but no inhibition was found against gram positive
bacteria. Further, these ethanol extracts were screened for in vitro
percentage cytotoxicity at different time periods (24 h, 48 h and 72 h)
of different dilutions. The in vivo plant extract inhibited the growth of
EAC mouse cell lines in the range of 65, 66, 78, and 88% at 100, 50,
25 & 12.5μg mL-1 but at 72 h of treatment. In case of the extract of in
vitro origin, the inhibition was found against EAC cell lines even at
48h. During spectrophotometric scanning, the extracts exhibited
different maxima (ʎ) - four peaks in in vitro extracts as against single
in in vivo preparation suggesting the possible change in the nature of
ingredients during micropropagation through tissue culture
techniques.
Abstract: Hyperglycaemia is a key factor that contributes to the
development of diabetes-related microvascular disease and a major
risk factor for endothelial dysfunction. In the current study, we have
explored glucose-induced abnormal intracellular calcium (Ca2+
i)
homeostasis in mouse microvessel endothelial cells (MMECs) in
high glucose (HG) (40mmol/L) versus control (low glucose, LG) (11
mmol/L). We demonstrated that the exposure of MMECs to HG for 3
days did not change basal Ca2+
i, however, there was a significant
increase of acetylcholine-induced Ca2+ entry. Western blots
illustrated that exposure to HG also increased STIM1 (Stromal
Interaction Molecule 1), but not Orai1 (the pore forming subunit),
protein expression levels. Although the link between HG-induced
changes in STIM1 expression, enhanced Ca2+ entry and endothelial
dysfunction requires further study, the current data are suggestive
that targeting these pathways may reduce the impact of HG on
endothelial function.
Abstract: This paper presents a new color face image database
for benchmarking of automatic face detection algorithms and human
skin segmentation techniques. It is named the VT-AAST image
database, and is divided into four parts. Part one is a set of 286 color
photographs that include a total of 1027 faces in the original format
given by our digital cameras, offering a wide range of difference in
orientation, pose, environment, illumination, facial expression and
race. Part two contains the same set in a different file format. The
third part is a set of corresponding image files that contain human
colored skin regions resulting from a manual segmentation
procedure. The fourth part of the database has the same regions
converted into grayscale. The database is available on-line for
noncommercial use. In this paper, descriptions of the database
development, organization, format as well as information needed for
benchmarking of algorithms are depicted in detail.
Abstract: A known iterative computational procedure is used for
internal normal ball loads calculation in statically loaded single-row,
angular-contact ball bearings, subjected to a known thrust load,
which is applied in the inner ring at the geometric bearing center line.
Numerical aspects of the iterative procedure are discussed.
Numerical examples results for a 218 angular-contact ball bearing
have been compared with those from the literature. Twenty figures
are presented showing the geometrical features, the behavior of the
convergence variables and the following parameters as functions of
the thrust load: normal ball loads, contact angle, distance between
curvature centers, and normal ball and axial deflections between the
raceways.
Abstract: Wide applicability of concurrent programming
practices in developing various software applications leads to
different concurrency errors amongst which data race is the most
important. Java provides greatest support for concurrent
programming by introducing various concurrency packages. Aspect
oriented programming (AOP) is modern programming paradigm
facilitating the runtime interception of events of interest and can be
effectively used to handle the concurrency problems. AspectJ being
an aspect oriented extension to java facilitates the application of
concepts of AOP for data race detection. Volatile variables are
usually considered thread safe, but they can become the possible
candidates of data races if non-atomic operations are performed
concurrently upon them. Various data race detection algorithms have
been proposed in the past but this issue of volatility and atomicity is
still unaddressed. The aim of this research is to propose some
suggestions for incorporating certain conditions for data race
detection in java programs at the volatile fields by taking into account
support for atomicity in java concurrency packages and making use
of pointcuts. Two simple test programs will demonstrate the results
of research. The results are verified on two different Java
Development Kits (JDKs) for the purpose of comparison.
Abstract: Lack of resources for road infrastructure financing is a
problem that currently affects not only eastern European economies
but also many other countries especially in relation to the impact of
global financial crisis. In this context, we are talking about the socalled
short-investment problem as a result of long-term lack of
investment resources. Based on an analysis of road infrastructure
financing in the Czech Republic this article points out at weaknesses
of current system and proposes a long-term planning methodology
supported by system approach. Within this methodology and using
created system dynamic model the article predicts the development of
short-investment problem in the Country and in reaction on the
downward trend of certain sources the article presents various
scenarios resulting from the change of the structure of financial
sources. In the discussion the article focuses more closely on the
possibility of introduction of tax on vehicles instead of taxes with
declining revenue streams and estimates its approximate price in
relation to reaching various solutions of short-investment in time.
Abstract: This research was aimed at determining the impact of conservation techniques including bench terrace, stone terrace, mulching, grass strip and intercropping on soil erosion at tobacco-based farming system at Progo Hulu subwatershed, Central Java, Indonesia. Research was conducted from September 2007 to September 2009, located at Progo Hulu subwatershed, Central Java, Indonesia. Research site divided into 27 land units, and experimental fields were grouped based on the soil type and slope, ie: 30%, 45% and 70%, with the following treatments: 1) ST0= stone terrace (control); 2) ST1= stone terrace + Setaria spacelata grass strip on a 5 cm height dike at terrace lips + tobacco stem mulch with dose of 50% (7 ton/ ha); 3) ST2= stone terrace + Setaria spacelata grass strip on a 5 cm height dike at terrace lips + tobacco stem mulch with dose of 100% (14 ton/ ha); 4) ST3= stone terrace + tobacco and red bean intercropping + tobacco stem mulch with dose of 50% (7 ton/ ha). 5) BT0= bench terrace (control); 6) BT1= bench terrace + Setaria spacelata grass strip at terrace lips + tobacco stem mulch with dose of 50% (7 ton/ ha); 7) BT2= bench terrace + Setaria spacelata grass strip at terrace lips + tobacco stem mulch with dose of 100% (14 ton/ ha); 8) BT3= bench terrace + tobacco and red bean intercropping + tobacco stem mulch with dose of 50% (7 ton/ ha). The results showed that the actual erosion rates of research site were higher than that of tolerance erosion with mean value 89.08 ton/ha/year and 33.40 ton/ha/year, respectively. These resulted in 69% of total research site (5,119.15 ha) highly degraded. Conservation technique of ST2 was the most effective in suppressing soil erosion, by 42.87%, following with BT2 as much 30.63%. Others suppressed erosion only less than 21%.
Abstract: Several trillion cigarettes produced worldwide annually lead to many thousands of kilograms of toxic waste. Cigarette butts (CBs) accumulate in the environment due to the poor biodegradability of the cellulose acetate filters. This paper presents some of the results from a continuing study on recycling CBs into fired clay bricks. Physico-mechanical properties of fired clay bricks manufactured with different percentages of CBs are reported and discussed. The results show that the density of fired bricks was reduced by up to 30 %, depending on the percentage of CBs incorporated into the raw materials. Similarly, the compressive strength of bricks tested decreased according to the percentage of CBs included in the mix. The thermal conductivity performance of bricks was improved by 51 and 58 % for 5 and 10 % CBs content respectively. Leaching tests were carried out to investigate the levels of possible leachates of heavy metals from the manufactured clay-CB bricks. The results revealed trace amounts of heavy metals.
Abstract: The present work presents a method of calculating the
ductility of rectangular sections of beams considering nonlinear
behavior of concrete and steel. This calculation procedure allows us
to trace the curvature of the section according to the bending
moment, and consequently deduce ductility. It also allowed us to
study the various parameters that affect the value of the ductility. A
comparison of the effect of maximum rates of tension steel, adopted
by the codes, ACI [1], EC8 [2] and RPA [3] on the value of the
ductility was made. It was concluded that the maximum rate of steels
permitted by the ACI [1] codes and RPA [3] are almost similar in
their effect on the ductility and too high. Therefore, the ductility
mobilized in case of an earthquake is low, the inverse of code EC8
[2]. Recommendations have been made in this direction.
Abstract: Mechanical interaction between endothelial cells (ECs) and the extracellular matrix (or collagen gel) is known to influence the sprouting response of endothelial cells during angiogenesis. This influence is believed to impact on the capability of endothelial cells to sense soluble chemical cues. Quantitative analysis of endothelial-cell-mediated displacement of the collagen gel provides a means to explore this mechanical interaction. Existing analysis in this context is generally limited to 2D settings. In this paper, we investigate the mechanical interaction between endothelial cells and the extracellular matrix in terms of the endothelial-cellmediated displacement of the collagen gel in both 2D and 3D. Digital image correlation and Digital volume correlation are applied on confocal reflectance image stacks to analyze cell-mediated displacement of the gel. The skeleton of the sprout is extracted from phase contrast images and superimposed on the displacement field to further investigate the link between the development of the sprout and the displacement of the gel.
Abstract: Since the 1980s, banks and financial service institutions have been running in an endless race of innovation to cope with the advancing technology, the fierce competition, and the more sophisticated and demanding customers. In order to guide their innovation efforts, several researches were conducted to identify the success and failure factors of new financial services. These mainly included organizational factors, marketplace factors and new service development process factors. They almost all emphasized the importance of customer and market orientation as a response to the highly perceptual and intangible characteristics of financial services. However, they deemphasized the critical characteristics of high involvement of risk and close correlation with the economic conditions, a factor that heavily contributed to the Global financial Crisis of 2008. This paper reviews the success and failure factors of new financial services. It then adds new perspectives emerging from the analysis of the role of innovation in the global financial crisis.
Abstract: Cross sections of As radionuclides in the interaction of natGe with 14-30 MeV protons have been deduced by off-line y-ray spectroscopy to find optimal reaction channels leading to radiotracers for positron emission tomography. The experimental results were compared with the previous results and those estimated by the compound nucleus reaction model.
Abstract: A mammography image is composed of low contrast area where the breast tissues and the breast abnormalities such as microcalcification can hardly be differentiated by the medical practitioner. This paper presents the application of active contour models (Snakes) for the segmentation of microcalcification in mammography images. Comparison on the microcalcifiation areas segmented by the Balloon Snake, Gradient Vector Flow (GVF) Snake, and Distance Snake is done against the true value of the microcalcification area. The true area value is the average microcalcification area in the original mammography image traced by the expert radiologists. From fifty images tested, the result obtained shows that the accuracy of the Balloon Snake, GVF Snake, and Distance Snake in segmenting boundaries of microcalcification are 96.01%, 95.74%, and 95.70% accuracy respectively. This implies that the Balloon Snake is a better segmentation method to locate the exact boundary of a microcalcification region.
Abstract: Cenozoic basalts found in Jiangsu province of eastern
China include tholeiites and alkali basalts. The present paper analyzed
the major, trace elements, rare earth elements of these Cenozoic
basalts and combined with Sr-Nd isotopic compositions proposed by
Chen et al. (1990)[1] in the literatures to discuss the petrogenesis of
these basalts and the geochemical characteristics of the source mantle.
Based on major, trace elements and fractional crystallization model
established by Brooks and Nielsen (1982)[2] we suggest that the
basaltic magma has experienced olivine + clinopyroxene fractionation
during its evolution. The chemical compositions of basaltic rocks from
Jiangsu province indicate that these basalts may belong to the same
magmatic system. Spidergrams reveal that Cenozoic basalts from
Jiangsu province have geochemical characteristics similar to those of
ocean island basalts(OIB). The slight positive Nb and Ti anomalies
found in basaltic rocks of this study suggest the presence of Ti-bearing
minerals in the mantle source and these Ti-bearing minerals had
contributed to basaltic magma during partial melting, indicating a
metasomatic event might have occurred before the partial melting.
Based on the Sr vs. Nd isotopic ratio plots, we suggest that Jiangsu
basalts may be derived from partial melting of mantle source which
may represent two-end members mixing of DMM and EM-I. Some
Jiangsu basaltic magma may be derived from partial melting of EM-I
heated by the upwelling asthenospheric mantle or asthenospheric
diapirism.
Abstract: The operation performance of a valveless micro-pump
is strongly dependent on the shape of connected nozzle/diffuser and
Reynolds number. The aims of present work are to compare the
performance curves of micropump with the original straight
nozzle/diffuser and contoured nozzle/diffuser under different back
pressure conditions. The tested valveless micropumps are assembled
of five pieces of patterned PMMA plates with hot-embracing
technique. The structures of central chamber, the inlet/outlet
reservoirs and the connected nozzle/diffuser are fabricated with laser
cutting machine. The micropump is actuated with circular-type PZT
film embraced on the bottom of central chamber. The deformation of
PZT membrane with various input voltages is measured with a
displacement laser probe. A simple testing facility is also constructed
to evaluate the performance curves for comparison.
In order to observe the evaluation of low Reynolds number
multiple vortex flow patterns within the micropump during suction
and pumping modes, the unsteady, incompressible laminar
three-dimensional Reynolds-averaged Navier-Stokes equations are
solved. The working fluid is DI water with constant thermo-physical
properties. The oscillating behavior of PZT film is modeled with the
moving boundary wall in way of UDF program. With the dynamic
mesh method, the instants pressure and velocity fields are obtained
and discussed.Results indicated that the volume flow rate is not
monotony increased with the oscillating frequency of PZT film,
regardless of the shapes of nozzle/diffuser. The present micropump
can generate the maximum volume flow rate of 13.53 ml/min when
the operation frequency is 64Hz and the input voltage is 140 volts.
The micropump with contoured nozzle/diffuser can provide 7ml/min
flow rate even when the back pressure is up to 400 mm-H2O. CFD
results revealed that the flow central chamber was occupied with
multiple pairs of counter-rotating vortices during suction and
pumping modes. The net volume flow rate over a complete
oscillating periodic of PZT
Abstract: Thermal behavior of fuel channel under loss of coolant accident (LOCA) is a major concern for nuclear reactor safety. LOCA along with failure of emergency cooling water system (ECC) may leads to mechanical deformations like sagging and ballooning. In order to understand the phenomenon an experiment has been carried out using 19 pin fuel element simulator. Main purpose of the experiment was to trace temperature profiles over the pressure tube, calandria tube and clad tubes of Indian Pressurized Heavy Water Reactor (IPHWR) under symmetrical and asymmetrical heat-up conditions. For simulating the fully voided scenario, symmetrical heating of pressure was carried out by injecting 13.2 KW (2 % of nominal power) to all the 19 pins and the temperatures of pressure tube, calandria tube and clad tubes were measured. During symmetrical heating the sagging of fuel channel was initiated at 460 °C and the highest temperature attained by PT was 650 °C . The decay heat from clad tubes was dissipated to moderator mainly by radiation and natural convection. The highest temperature of 680 °C was observed over the outer ring of clad tubes of fuel simulator. Again, to simulate partially voided condition, asymmetrical heating of pressure was carried out by supplying 8.0 kW power to upper 8 pins of fuel simulator and temperature profiles were measured. Along the circumference of pressure tube (PT) the highest temperature difference of 320 °C was observed, which highlights the magnitude of thermal stresses under partially voided conditions.
Abstract: Buckling-Restrained Braced Frame system(BRBFs)
are a new type of steel seismic-load-resisting system that has found
use in several countries because of its efficiency and its promise of
seismic performance far superior to that of conventional braced
frames. The system is addressed in the 2005 edition of the AISC
Seismic Provisions for Structural Steel Buildings, also a set of design
provisions has been developed by NEHRP. This report illustrates the
seismic design of buckling restrained braced frames and compares
the result of design in the application of earthquake load for ordinary
bracing systems and buckling restrained bracing systems to see the
advantage and disadvantages of this new type of seismic resisting
system in comparison with the old Ordinary Concentric Braced
Frame systems (OCBFs); they are defined by the provisions
governing their design.
Abstract: Repeated additions of the unfertilized bacteria led to
increase the activity of Nitrogen-fixing bacteria in the root zone with
drip irrigation system compared to traditional manual vaccination to
increase the proportion of Nitrogen from 29% to 64%, and the
efficiency of adding Nitrogen fertilizer did not exceed 9.5% while
dropped to 4%, due to the amount of fertilizer added was not exceed
20kg N/h, and the second was the existence of a large amount of
available Nitrogen in the soil by fixation, while the efficiency of
irrigation system between 2.08 to 2.26 kg/m3.
Abstract: This paper reviews the optimization available
transmission capability (ATC) of power systems using a device of
FACTS named SSSC equipped with energy storage devices. So that,
emplacement and improvement of parameters of SSSC will be
illustrated. Thus, voltage magnitude constraints of network buses,
line transient stability constraints and voltage breakdown constraints
are considered. To help the calculations, a comprehensive program in
DELPHI is provided, which is able to simulate and trace the
parameters of SSSC has been installed on a specific line.
Furthermore, the provided program is able to compute ATC, TTC
and maximum value of their enhancement after using SSSC.
Abstract: The running logs of a process hold valuable
information about its executed activity behavior and generated activity
logic structure. Theses informative logs can be extracted, analyzed and
utilized to improve the efficiencies of the process's execution and
conduction. One of the techniques used to accomplish the process
improvement is called as process mining. To mine similar processes is
such an improvement mission in process mining. Rather than directly
mining similar processes using a single comparing coefficient or a
complicate fitness function, this paper presents a simplified heuristic
process mining algorithm with two similarity comparisons that are
able to relatively conform the activity logic sequences (traces) of
mining processes with those of a normalized (regularized) one. The
relative process conformance is to find which of the mining processes
match the required activity sequences and relationships, further for
necessary and sufficient applications of the mined processes to process
improvements. One similarity presented is defined by the relationships
in terms of the number of similar activity sequences existing in
different processes; another similarity expresses the degree of the
similar (identical) activity sequences among the conforming processes.
Since these two similarities are with respect to certain typical behavior
(activity sequences) occurred in an entire process, the common
problems, such as the inappropriateness of an absolute comparison and
the incapability of an intrinsic information elicitation, which are often
appeared in other process conforming techniques, can be solved by the
relative process comparison presented in this paper. To demonstrate
the potentiality of the proposed algorithm, a numerical example is
illustrated.