Abstract: In present scenario, cardiovascular problems are growing challenge for researchers and physiologists. As heart disease have no geographic, gender or socioeconomic specific reasons; detecting cardiac irregularities at early stage followed by quick and correct treatment is very important. Electrocardiogram is the finest tool for continuous monitoring of heart activity. Heart rate variability (HRV) is used to measure naturally occurring oscillations between consecutive cardiac cycles. Analysis of this variability is carried out using time domain, frequency domain and non-linear parameters. This paper presents HRV analysis of the online dataset for normal sinus rhythm (taken as healthy subject) and sudden cardiac death (SCD subject) using all three methods computing values for parameters like standard deviation of node to node intervals (SDNN), square root of mean of the sequences of difference between adjacent RR intervals (RMSSD), mean of R to R intervals (mean RR) in time domain, very low-frequency (VLF), low-frequency (LF), high frequency (HF) and ratio of low to high frequency (LF/HF ratio) in frequency domain and Poincare plot for non linear analysis. To differentiate HRV of healthy subject from subject died with SCD, k –nearest neighbor (k-NN) classifier has been used because of its high accuracy. Results show highly reduced values for all stated parameters for SCD subjects as compared to healthy ones. As the dataset used for SCD patients is recording of their ECG signal one hour prior to their death, it is therefore, verified with an accuracy of 95% that proposed algorithm can identify mortality risk of a patient one hour before its death. The identification of a patient’s mortality risk at such an early stage may prevent him/her meeting sudden death if in-time and right treatment is given by the doctor.
Abstract: In this study, it was tried to identify some heart rhythm disorders by electrocardiography (ECG) data that is taken from MIT-BIH arrhythmia database by subtracting the required features, presenting to artificial neural networks (ANN), artificial immune systems (AIS), artificial neural network based on artificial immune system (AIS-ANN) and particle swarm optimization based artificial neural network (PSO-NN) classifier systems. The main purpose of this study is to evaluate the performance of hybrid AIS-ANN and PSO-ANN classifiers with regard to the ANN and AIS. For this purpose, the normal sinus rhythm (NSR), atrial premature contraction (APC), sinus arrhythmia (SA), ventricular trigeminy (VTI), ventricular tachycardia (VTK) and atrial fibrillation (AF) data for each of the RR intervals were found. Then these data in the form of pairs (NSR-APC, NSR-SA, NSR-VTI, NSR-VTK and NSR-AF) is created by combining discrete wavelet transform which is applied to each of these two groups of data and two different data sets with 9 and 27 features were obtained from each of them after data reduction. Afterwards, the data randomly was firstly mixed within themselves, and then 4-fold cross validation method was applied to create the training and testing data. The training and testing accuracy rates and training time are compared with each other.
As a result, performances of the hybrid classification systems, AIS-ANN and PSO-ANN were seen to be close to the performance of the ANN system. Also, the results of the hybrid systems were much better than AIS, too. However, ANN had much shorter period of training time than other systems. In terms of training times, ANN was followed by PSO-ANN, AIS-ANN and AIS systems respectively. Also, the features that extracted from the data affected the classification results significantly.
Abstract: Non linear methods of heart rate variability (HRV) analysis are becoming more popular. It has been observed that complexity measures quantify the regularity and uncertainty of cardiovascular RR-interval time series. In the present work, SampEn has been evaluated in healthy normal sinus rhythm (NSR) male and female subjects for different data lengths and tolerance level r. It is demonstrated that SampEn is small for higher values of tolerance r. Also SampEn value of healthy female group is higher than that of healthy male group for short data length and with increase in data length both groups overlap each other and it is difficult to distinguish them. The SampEn gives inaccurate results by assigning higher value to female group, because male subject have more complex HRV pattern than that of female subjects. Therefore, this traditional algorithm exhibits higher complexity for healthy female subjects than for healthy male subjects, which is misleading observation. This may be due to the fact that SampEn do not account for multiple time scales inherent in the physiologic time series and the hidden spatial and temporal fluctuations remains unexplored.
Abstract: Obstructive sleep apnea in patients, between 70 and 80
percent, can be cured with just a posture correcting. The most import
thing to do this is detection of obstructive sleep apnea. Detection of
obstructive sleep apnea can be performed through heart rate variability
analysis using power spectrum density analysis. After HRV analysis
we needed to know the current position information for correcting the
position. The pressure sensors of the array type were used to obtain
position information. These sensors can obtain information from the
experimenter about position. In addition, air cylinder corrected the
position of the experimenter by lifting the bed. The experimenter can
be changed position without breaking during sleep by the system.
Polysomnograph recording were obtained from 10 patients. The
results of HRV analysis were that NLF and LF/HF ratio increased,
while NHF decreased during OSA. Position change had to be done the
periods.
Abstract: In this paper, an automatic detecting algorithm for
QRS complex detecting was applied for analyzing ECG recordings
and five criteria for dangerous arrhythmia diagnosing are applied for a
protocol type of automatic arrhythmia diagnosing system. The
automatic detecting algorithm applied in this paper detected the
distribution of QRS complexes in ECG recordings and related
information, such as heart rate and RR interval. In this investigation,
twenty sampled ECG recordings of patients with different pathologic
conditions were collected for off-line analysis. A combinative
application of four digital filters for bettering ECG signals and
promoting detecting rate for QRS complex was proposed as
pre-processing. Both of hardware filters and digital filters were
applied to eliminate different types of noises mixed with ECG
recordings. Then, an automatic detecting algorithm of QRS complex
was applied for verifying the distribution of QRS complex. Finally,
the quantitative clinic criteria for diagnosing arrhythmia were
programmed in a practical application for automatic arrhythmia
diagnosing as a post-processor. The results of diagnoses by automatic
dangerous arrhythmia diagnosing were compared with the results of
off-line diagnoses by experienced clinic physicians. The results of
comparison showed the application of automatic dangerous
arrhythmia diagnosis performed a matching rate of 95% compared
with an experienced physician-s diagnoses.
Abstract: This paper describes a new method for extracting the fetal heart rate (fHR) and the fetal heart rate variability (fHRV) signal non-invasively using abdominal maternal electrocardiogram (mECG) recordings. The extraction is based on the fundamental frequency (Fourier-s) theorem. The fundamental frequency of the mother-s electrocardiogram signal (fo-m) is calculated directly from the abdominal signal. The heart rate of the fetus is usually higher than that of the mother; as a result, the fundamental frequency of the fetal-s electrocardiogram signal (fo-f) is higher than that of the mother-s (fo-f > fo-m). Notch filters to suppress mother-s higher harmonics were designed; then a bandpass filter to target fo-f and reject fo-m is implemented. Although the bandpass filter will pass some other frequencies (harmonics), we have shown in this study that those harmonics are actually carried on fo-f, and thus have no impact on the evaluation of the beat-to-beat changes (RR intervals). The oscillations of the time-domain extracted signal represent the RR intervals. We have also shown in this study that zero-to-zero evaluation of the periods is more accurate than the peak-to-peak evaluation. This method is evaluated both on simulated signals and on different abdominal recordings obtained at different gestational ages.
Abstract: We have developed a computer program consisting of
6 subtests assessing the children hand dexterity applicable in the
rehabilitation medicine. We have carried out a normative study on a
representative sample of 285 children aged from 7 to 15 (mean age
11.3) and we have proposed clinical standards for three age groups
(7-9, 9-11, 12-15 years). We have shown statistical significance of
differences among the corresponding mean values of the task time
completion. We have also found a strong correlation between the task
time completion and the age of the subjects, as well as we have
performed the test-retest reliability checks in the sample of 84
children, giving the high values of the Pearson coefficients for the
dominant and non-dominant hand in the range 0.740.97 and
0.620.93, respectively.
A new MATLAB-based programming tool aiming at analysis of
cardiologic RR intervals and blood pressure descriptors, is worked
out, too. For each set of data, ten different parameters are extracted: 2
in time domain, 4 in frequency domain and 4 in Poincaré plot
analysis. In addition twelve different parameters of baroreflex
sensitivity are calculated. All these data sets can be visualized in time
domain together with their power spectra and Poincaré plots. If
available, the respiratory oscillation curves can be also plotted for
comparison. Another application processes biological data obtained
from BLAST analysis.
Abstract: The RR interval series is non-stationary and unevenly
spaced in time. For estimating its power spectral density (PSD) using
traditional techniques like FFT, require resampling at uniform
intervals. The researchers have used different interpolation
techniques as resampling methods. All these resampling methods
introduce the low pass filtering effect in the power spectrum. The
lomb transform is a means of obtaining PSD estimates directly from
irregularly sampled RR interval series, thus avoiding resampling. In
this work, the superiority of Lomb transform method has been
established over FFT based approach, after applying linear and
cubicspline interpolation as resampling methods, in terms of
reproduction of exact frequency locations as well as the relative
magnitudes of each spectral component.
Abstract: The measurement of anesthetic depth is necessary in
anesthesiology. NN10 is very simple method among the RR intervals
analysis methods. NN10 parameter means the numbers of above the 10
ms intervals of the normal to normal RR intervals.
Bispectrum analysis is defined as 2D FFT. EEG signal reflected the
non-linear peristalsis phenomena according to the change brain
function. After analyzing the bispectrum of the 2 dimension, the most
significant power spectrum density peaks appeared abundantly at the
specific area in awakening and anesthesia state. These points are
utilized to create the new index since many peaks appeared at the
specific area in the frequency coordinate. The measured range of an
index was 0-100. An index is 20-50 at an anesthesia, while the index is
90-60 at the awake.
In this paper, the relation between NN10 parameter using ECG and
bisepctrum index using EEG is observed to estimate the depth of
anesthesia during anesthesia and then we estimated the utility of the
anesthetic.