Abstract: Let us consider that the entire universe is composed of
a single hydrogen atom within which the electron is moving around
the proton. In this case, according to classical theories of physics,
radiation, photons respectively, should be absorbed by the electron.
Depending on the number of photons absorbed, the electron radius of
rotation around the proton is established. Until now, the principle of
photons absorption by electrons and the electron transition to a new
energy level, namely to a higher radius of rotation around the proton,
is not clarified in physics. This paper aims to demonstrate that
radiation, photons respectively, have mass and negative electrostatic
charge similar to electrons but infinitely smaller. The experiments
which demonstrate this theory are simple: thermal expansion,
photoelectric effect and thermonuclear reaction.
Abstract: In the immunologic sense, clinical infection is a state
of failure of the immune system to combat the pathogenic weapon of
the bacteria invading the host. A motile gram negative vibroid
organism associated with marked mono and poly nuclear cell
responses was traced during the examination of a clinical material
from an infected common carp Cyprinus carpio. On primary plate
culture, growth was shown to be pure, dense population of an
Aeromonas-like colony morphotype. The pure isolate was found to
be; Aerobic, facultatively anaerobic, non-halophilic, grew at 0C, and
37C, oxidase positive utilizes glucose through fermentative pathway,
resist 0/129 and novobiocin, produces alanine and lysine
decarboxylases but non-producing ornithine dehydrolases. Tests for
the in vitro determinants of pathogenicity has shown to be; Betahaemolytic
onto blood agar, gelatinase, casienase and amylase
producer. Three in vivo determinants of pathogenicity were tested as,
the lethal dose fifty, the pathogenesis and pathogenicity. It was
evident that 0.1 milliliter of the causal bacterial cell suspension of a
density 1 x 107 CFU/ml injected intramuscularly into an average of
100gms fish toke five days incubation period, then at the day six
morbidity and mortality were initiated. LD50 was recorded at the day
12 post-infection. Use of an LD50 doses to study the pathogenicity,
reveals mononuclear and polynuclear cell responses, on examining
the stained direct films of the clinical materials from the
experimentally infected fish. Re-isolation tests confirm that the reisolant
is same. The course of the infection in natural case was shown
manifestation of; skin ulceration, haemorrhage and descaling. On
evisceration, the internal organs were shown; congestion in the
intestines, spleen and, air sacs. The induced infection showed a
milder form of these manifestations. The grading of the virulence of
this organism was virulent causing chronic course of infections as
indicated from the pathogenesis and pathogenicity studies. Thus the
infectious bacteria were consistent with Aeromonas hydrophila, and
the infection was chronic.
Abstract: Current research is targeting new molecular
mechanisms that underlie non-alcoholic fatty liver disease (NAFLD)
and associated metabolic disorders like non-alcoholic steatohepatitis
(NASH). Forty New Zealand White rabbits have been used and fed a
high protein (HP) and energy diet based on grains and containing
11.76 MJ/kg. Boron added to 3 experimental groups’ drinking waters
(30 mg boron/L) as boron compounds. Biochemical analysis
including boron levels, and nuclear magnetic resonance (NMR) based
metabolomics evaluation, and mRNA expression of peroxisome
proliferator-activated receptor (PPAR) family was performed. LDLcholesterol
concentrations alone were decreased in all the
experimental groups. Boron levels in serum and feces were increased.
Content of acetate was in about 2x higher for anhydrous borax group,
at least 3x higher for boric acid group. PPARα mRNA expression
was significantly decreased in boric acid group. Anhydrous borax
attenuated mRNA levels of PPARγ, which was further suppressed by
boric acid. Boron supplementation decreased the degenerative
alterations in hepatocytes. Except borax group other boron groups did
not have a pronounced change in tubular epithels of kidney. In
conclusion, high protein and energy diet leads hepatocytes’
degenerative changes which can be prevented by boron
supplementation. Boric acid seems to be more effective in this
situation.
Abstract: In this research, TRACE model of Chinshan BWR/4
nuclear power plant (NPP) has been developed for the simulation and
analysis of ultimate response guideline (URG).The main actions of
URG are the depressurization and low pressure water injection of
reactor and containment venting. This research focuses to verify the
URG efficiency under Fukushima-like conditions. TRACE analysis
results show that the URG can keep the PCT below the criteria
1088.7 K under Fukushima-like conditions. It indicated that Chinshan
NPP was safe.
Abstract: Diagram and drawing are important ways to
communicate and the reproduce of architectural design, Due to the
development of information and communication technology, the
professional thinking of architecture and interior design are also
change rapidly. In development process of design, diagram always
play very important role. This study is based on diagram theories,
observe and record interaction between man and objects, objects and
space, and space and time in a modern nuclear family. Construct a
method for diagram to systematically and visualized describe the
space plan of a modern nuclear family toward an intelligent design, to
assist designer to retrieve information and review event pattern of past
and present.
Abstract: Reflux condensation occurs in vertical channels and tubes when there is an upward core flow of vapour (or gas-vapour mixture) and a downward flow of the liquid film. The understanding of this condensation configuration is crucial in the design of reflux condensers, distillation columns, and in loss-of-coolant safety analyses in nuclear power plant steam generators. The unique feature of this flow is the upward flow of the vapour-gas mixture (or pure vapour) that retards the liquid flow via shear at the liquid-mixture interface. The present model solves the full, elliptic governing equations in both the film and the gas-vapour core flow. The computational mesh is non-orthogonal and adapts dynamically the phase interface, thus produces a sharp and accurate interface. Shear forces and heat and mass transfer at the interface are accounted for fundamentally. This modeling is a big step ahead of current capabilities by removing the limitations of previous reflux condensation models which inherently cannot account for the detailed local balances of shear, mass, and heat transfer at the interface. Discretisation has been done based on finite volume method and co-located variable storage scheme. An in-house computer code was developed to implement the numerical solution scheme. Detailed results are presented for laminar reflux condensation from steam-air mixtures flowing in vertical parallel plate channels. The results include velocity and gas mass fraction profiles, as well as axial variations of film thickness.
Abstract: The textile industry plays a major role in the economy
of India and on the other side of the coin it is the major source for
water pollution. As azo dyes is the largest dye class they are
extensively used in many fields such as textile industry, leather
tanning industry, paper production, food, color photography,
pharmaceuticals and medicine, cosmetic, hair colorings, wood
staining, agricultural, biological and chemical research etc. In
addition to these, they can have acute and/or chronic effects on
organisms depending on their concentration and length of exposure
when they discharged as effluent in the environment. The aim of this
study was to assess the genotoxic and histotoxic potentials of
environmentally relevant concentrations of C. I. Reactive Red 120
(RR 120) on Catla catla, important edible freshwater fingerlings. For
this, healthy Catla catla fingerlings were procured from the
Government Fish Farm and acclimatized in 100 L capacity and
continuously aerated glass aquarium in laboratory for 15 days.
According to APHA some physic-chemical parameters were
measured and maintained such as temperature, pH, dissolve oxygen,
alkalinity, total hardness. Water along with excreta had been changed
every 24 hrs. All fingerlings were fed artificial food palates once a
day @ body weight. After 15 days fingerlings were grouped in 5 (10
in each) and exposed to various concentrations of RR 120 (Control,
10, 20, 30 and 40 mg.l-1) and samples (peripheral blood and gills,
kidney) were collected and analyzed at 96 hrs. All results were
compared with the control. Micronuclei (MN), nuclear buds (NB),
fragmented-apoptotic (FA) and bi-nucleated (BN) cells in blood
smears and in tissues (gills and kidney cells) were observed.
Prominent histopathological alterations were noticed in gills such as
aneurism, hyperplasia, degenerated central axis, lifting of gill
epithelium, curved secondary gill lamellae etc. Similarly kidney
showed some detrimental changes like shrunken glomeruli with
increased periglomerular space, degenerated renal tubules etc. Both
haematological and histopathological changes clearly reveal the toxic
potential of RR 120. This work concludes that water pollution
assessment can be done by these two biomarkers which provide
baseline to the further chromosomal or molecular work.
Abstract: Considering palm oil as non-drying oil owing to its
low iodine value, an attempt was taken to increase the unsaturation in
the fatty acid chains of palm oil for the preparation of alkyds. To
increase the unsaturation in the palm oil, sulphuric acid (SA) and
para-toluene sulphonic acid (PTSA) was used prior to alcoholysis for
the dehydration process. The iodine number of the oil samples was
checked for the unsaturation measurement by Wijs method. Alkyd
resin was prepared using the dehydrated palm oil by following
alcoholysis and esterification reaction. To improve the film properties
0.5wt.% multi-wall carbon nano tubes (MWCNTs) were used to
manufacture polymeric film. The properties of the resins were
characterized by various physico-chemical properties such as density,
viscosity, iodine value, saponification value, etc. Structural
elucidation was confirmed by Fourier transform of infrared
spectroscopy and proton nuclear magnetic resonance; surfaces of the
films were examined by field-emission scanning electron microscope.
In addition, pencil hardness and chemical resistivity was also
measured by using standard methods. The effect of enhancement of
the unsaturation in the fatty acid chain found significant and
motivational. The resin prepared with dehydrated palm oil showed
improved properties regarding hardness and chemical resistivity
testing. The incorporation of MWCNTs enhanced the thermal
stability and hardness of the films as well.
Abstract: The thermal control in many systems is widely
accomplished applying mixed convection process due to its low cost,
reliability and easy maintenance. Typical applications include the
aircraft electronic equipment, rotating-disc heat exchangers, turbo
machinery, and nuclear reactors, etc. Natural convection in an inclined
square enclosure heated via wall heater has been studied numerically.
Finite volume method is used for solving momentum and energy
equations in the form of stream function–vorticity. The right and left
walls are kept at a constant temperature, while the other parts are
adiabatic. The range of the inclination angle covers a whole revolution.
The method is validated for a vertical cavity. A general power law
dependence of the Nusselt number with respect to the Rayleigh
number with the coefficient and exponent as functions of the
inclination angle is presented. For a fixed Rayleigh number, the
inclination angle increases or decreases is found.
Abstract: Evaluated nuclear decay data for the 217Po nuclide is
presented in the present work. These data include recommended
values for the half-life T1/2, α-, β-- and γ-ray emission energies and
probabilities. Decay data from 221Rn α and 217Bi β—decays are
presented. Q(α) has been updated based on the recent published work
of the Atomic Mass Evaluation AME2012. In addition, the logft
values were calculated using the Logft program from the ENSDF
evaluation package. Moreover, the total internal conversion electrons
and the K-shell to L-shell and L-shell to M-shell and to N-shell
conversion electrons ratios K/L, L/M and L/N have been calculated
using Bricc program. Meanwhile, recommendation values or the
multi-polarities have been assigned based on recently measurement
yield a better intensity balance at the 254 keV and 264 keV gamma
transitions.
Abstract: Doxorubicin, also known as Adriamycin, is an
anthracycline class of drug used in cancer chemotherapy. It is used in
the treatment of non-Hodgkin’s lymphoma, multiple myeloma, acute
leukemia, breast cancer, lung cancer, endometrium cancer and ovary
cancers. It functions via intercalating DNA and ultimately killing
cancer cells. The major side effects of doxorubicin are hair loss,
myelosuppression, nausea & vomiting, oesophagitis, diarrhea, heart
damage and liver dysfunction. The minor modifications in the
structure of compound exhibit large variation in the biological
activity, has prompted us to carry out the synthesis of sulfonamide
derivatives. Sulfonamide is an important feature with broad spectrum
of biological activity such as antiviral, antifungal, diuretics, antiinflammatory,
antibacterial and anticancer activities. Structure of the
synthesized compound N-(1-methyl-2-oxo-2-N-methyl anilinoethyl)
benzene sulfonamide confirmed by proton nuclear magnetic
resonance (1H NMR),13C NMR, Mass and FTIR spectroscopic tools
to assure the position of all protons and hence stereochemistry of the
molecule. Further we have reported the binding potential of
synthesized sulfonamide analogues in comparison to doxorubicin
drug using Auto Dock 4.2 software. Computational binding energy
(B.E.) and inhibitory constant (Ki) has been evaluated for the
synthesized compound in comparison of doxorubicin against Poly
(dA-dT).Poly (dA-dT) and Poly (dG-dC).Poly (dG-dC) sequences.
The in vitro cytotoxic study against human breast cancer cell lines
confirms the better anticancer activity of the synthesized compound
over currently in use anticancer drug doxorubicin. The IC50 value of
the synthesized compound is 7.12 μM whereas for doxorubicin is 7.2
μM.
Abstract: A thermosyphon system is a heat transfer loop which
operates on the basis of gravity and buoyancy forces. It guarantees a
good reliability and low maintenance cost as it does not involve any
mechanical pump. Therefore, it can be used in many industrial
applications such as refrigeration and air conditioning, electronic
cooling, nuclear reactors, geothermal heat extraction, etc. But flow
instabilities and loop configuration are the major problems in this
system. Several previous researchers studied that stabilities can be
suppressed by using nanofluids as loop fluid. In the present study a
rectangular thermosyphon loop with end heat exchangers are
considered for the study. This configuration is more appropriate for
many practical applications such as solar water heater, geothermal
heat extraction, etc. In the present work, steady-state analysis is
carried out on thermosyphon loop with parallel flow coaxial heat
exchangers at heat source and heat sink. In this loop nanofluid is
considered as the loop fluid and water is considered as the external
fluid in both hot and cold heat exchangers. For this analysis onedimensional
homogeneous model is developed. In this model,
conservation equations like conservation of mass, momentum, energy
are discretized using finite difference method. A computer code is
written in MATLAB to simulate the flow in thermosyphon loop. A
comparison in terms of heat transfer is made between water and
nanofluid as working fluids in the loop.
Abstract: Currently, thorium fuel has been especially noticed
because of its proliferation resistance than long half-life alpha emitter
minor actinides, breeding capability in fast and thermal neutron flux
and mono-isotopic naturally abundant. In recent years, efficiency of
minor actinide burning up in PWRs has been investigated. Hence, a
minor actinide-contained thorium based fuel matrix can confront both
proliferation resistance and nuclear waste depletion aims. In the
present work, minor actinide depletion rate in a CANDU-type nuclear
core modeled using MCNP code has been investigated. The obtained
effects of minor actinide load as mixture of thorium fuel matrix on
the core neutronics has been studied with comparing presence and
non-presence of minor actinide component in the fuel matrix.
Depletion rate of minor actinides in the MA-contained fuel has been
calculated using different power loads. According to the obtained
computational data, minor actinide loading in the modeled core
results in more negative reactivity coefficients. The MA-contained
fuel achieves less radial peaking factor in the modeled core. The
obtained computational results showed 140 kg of 464 kg initial load
of minor actinide has been depleted in during a 6-year burn up in 10
MW power.
Abstract: Currently, seismic probabilistic risk assessments
(SPRA) for nuclear facilities use In-Structure Response Spectra
(ISRS) in the calculation of fragilities for systems and components.
ISRS are calculated via dynamic analyses of the host building
subjected to two orthogonal components of horizontal ground
motion. Each component is defined as the median motion in any
horizontal direction. Structural engineers applied the components
along selected X and Y Cartesian axes. The ISRS at different
locations in the building are also calculated in the X and Y directions.
The choice of the directions of X and Y are not specified by the
ground motion model with respect to geographic coordinates, and are
rather arbitrarily selected by the structural engineer. Normally, X and
Y coincide with the “principal” axes of the building, in the
understanding that this practice is generally conservative. For SPRA
purposes, however, it is desirable to remove any conservatism in the
estimates of median ISRS. This paper examines the effects of the
direction of horizontal seismic motion on the ISRS on typical nuclear
structure. We also evaluate the variability of ISRS calculated along
different horizontal directions. Our results indicate that some central
measures of the ISRS provide robust estimates that are practically
independent of the selection of the directions of the horizontal
Cartesian axes.
Abstract: In regards to the energy sector in the modern period,
two points were raised. First is a vast and growing energy demand, and
second is an environmental impact associated with it. The enormous
consumption of fossil fuel to the mobile unit is leading to its rapid
depletion. Nuclear power is not the only problem. A modal shift that
utilizes personal transporters and independent power, in order to
realize a sustainable society, is very effective. The author proposes that
the world will continue to work on this. Energy of the future society,
innovation in battery technology and the use of natural energy is a big
key. And it is also necessary in order to save on energy consumption.
Abstract: The operation of nuclear power plants involves
continuous monitoring of the environment in their area. This
monitoring is performed using a complex data acquisition system,
which collects status information about the system itself and values
of many important physical variables e.g. temperature, humidity,
dose rate etc. This paper describes a proposal and optimization of
communication that takes place in teledosimetric system between the
central control server responsible for the data processing and storing
and the decentralized measuring stations, which are measuring the
physical variables. Analyzes of ongoing communication were
performed and consequently the optimization of the system
architecture and communication was done.
Abstract: GRF, Growth regulating factor, genes encode a novel
class of plant-specific transcription factors. The GRF proteins play a
role in the regulation of cell numbers in young and growing tissues
and may act as transcription activations in growth and development
of plants. Identification of GRF genes and their expression are
important in plants to performance of the growth and development of
various organs. In this study, to better understanding the structural
and functional differences of GRFs family, 45 GRF proteins
sequences in A. thaliana, Z. mays, O. sativa, B. napus, B. rapa, H.
vulgare and S. bicolor, have been collected and analyzed through
bioinformatics data mining. As a result, in secondary structure of
GRFs, the number of alpha helices was more than beta sheets and in
all of them QLQ domains were completely in the biggest alpha helix.
In all GRFs, QLQ and WRC domains were completely protected
except in AtGRF9. These proteins have no trans-membrane domain
and due to have nuclear localization signals act in nuclear and they
are component of unstable proteins in the test tube.
Abstract: This article describes the information system for
measuring and evaluating the dose rate in the environment of nuclear
power plants Mochovce and Bohunice in Slovakia.
The article presents the results achieved in the implementation of
the EU project – Research of monitoring and evaluation of nonstandard
conditions in the area of nuclear power plants. The
objectives included improving the system of acquisition, measuring
and evaluating data with mobile and autonomous units applying new
knowledge from research.
The article provides basic and specific features of the system and
compared to the previous version of the system, also new functions.
Abstract: Kuosheng nuclear power plant (NPP) is a BWR/6 type
NPP and located on the northern coast of Taiwan. First, Kuosheng
NPP TRACE model were developed in this research. In order to assess
the system response of Kuosheng NPP TRACE model, startup tests
data were used to evaluate Kuosheng NPP TRACE model. Second, the
overpressurization transient analysis of Kuosheng NPP TRACE model
was performed. Besides, in order to confirm the mechanical property
and integrity of fuel rods, FRAPTRAN analysis was also performed in
this study.
Abstract: This work studied the ability of adipose tissue-derived
mesenchymal stromal cells (MSCs) to form stroma for expansion of
cord blood hematopoietic cells. We showed that 72-hour interaction
of MSCs with cord blood mononuclear cells (MNCs) in vitro at
atmospheric (20%) and low (5%) O2 conditions increased the
expression of ICAM-1, HCAM (at the beginning of interaction) on
MSCs. Viability of MSCs and MNCs were maintained at high level.
Adhesion of MNCs to MSCs was faster at 20% O2. MSCs promoted
the proliferation of adhered MNCs to form the suspension containing
great number of hematopoietic colony-forming units, and this effect
was more pronounced at 5% O2. Thus, adipose-derived MSCs
supplied sufficient stromal support to cord blood MNCs both at 20%
and 5% О2, providing their adhesion with further expansion of new
generation of different hematopoietic lineages.