Abstract: Development of a method to estimate gene functions is
an important task in bioinformatics. One of the approaches for the
annotation is the identification of the metabolic pathway that genes are
involved in. Since gene expression data reflect various intracellular
phenomena, those data are considered to be related with genes’
functions. However, it has been difficult to estimate the gene function
with high accuracy. It is considered that the low accuracy of the
estimation is caused by the difficulty of accurately measuring a gene
expression. Even though they are measured under the same condition,
the gene expressions will vary usually. In this study, we proposed a
feature extraction method focusing on the variability of gene
expressions to estimate the genes' metabolic pathway accurately. First,
we estimated the distribution of each gene expression from replicate
data. Next, we calculated the similarity between all gene pairs by KL
divergence, which is a method for calculating the similarity between
distributions. Finally, we utilized the similarity vectors as feature
vectors and trained the multiclass SVM for identifying the genes'
metabolic pathway. To evaluate our developed method, we applied the
method to budding yeast and trained the multiclass SVM for
identifying the seven metabolic pathways. As a result, the accuracy
that calculated by our developed method was higher than the one that
calculated from the raw gene expression data. Thus, our developed
method combined with KL divergence is useful for identifying the
genes' metabolic pathway.
Abstract: The object of the present paper is to investigate several
general families of bilinear and bilateral generating functions with
different argument for the Gauss’ hypergeometric polynomials.
Abstract: The investigation in the present paper is to obtain
certain types of relations for the well known hypergeometric functions
by employing the technique of fractional derivative and integral.
Abstract: We present a trigonometric scheme to approximate a
circular arc with its two end points and two end tangents/unit
tangents. A rational cubic trigonometric Bézier curve is constructed
whose end control points are defined by the end points of the circular
arc. Weight functions and the remaining control points of the cubic
trigonometric Bézier curve are estimated by variational approach to
reproduce a circular arc. The radius error is calculated and found less
than the existing techniques.
Abstract: This paper proposes a new technique to design a
fixed-structure robust loop shaping controller for the pneumatic
servosystem. In this paper, a new method based on a particle swarm
optimization (PSO) algorithm for tuning the weighting function
parameters to design an H∞ controller is presented. The PSO
algorithm is used to minimize the infinity norm of the transfer
function of the nominal closed loop system to obtain the optimal
parameters of the weighting functions. The optimal stability margin is
used as an objective in PSO for selecting the optimal weighting
parameters; it is shown that the proposed method can simplify the
design procedure of H∞ control to obtain optimal robust controller for
pneumatic servosystem. In addition, the order of the proposed
controller is much lower than that of the conventional robust loop
shaping controller, making it easy to implement in practical works.
Also two-degree-of-freedom (2DOF) control design procedure is
proposed to improve tracking performance in the face of noise and
disturbance. Result of simulations demonstrates the advantages of the
proposed controller in terms of simple structure and robustness
against plant perturbations and disturbances.
Abstract: The author introduced the integral operator , by using this
operator a new subclasses of analytic functions are introduced. For
these classes, several Fekete-Szeg¨ type coefficient inequalities are
obtained.
Abstract: In this work, a Multi-Level Artificial Bee Colony
(called MLABC) for optimizing numerical test functions is presented.
In MLABC, two species are used. The first species employs n
colonies where each of them optimizes the complete solution vector.
The cooperation between these colonies is carried out by exchanging
information through a leader colony, which contains a set of elite
bees. The second species uses a cooperative approach in which the
complete solution vector is divided to k sub-vectors, and each of
these sub-vectors is optimized by a colony. The cooperation between
these colonies is carried out by compiling sub-vectors into the
complete solution vector. Finally, the cooperation between two
species is obtained by exchanging information. The proposed
algorithm is tested on a set of well-known test functions. The results
show that MLABC algorithm provides efficiency and robustness to
solve numerical functions.
Abstract: This paper represents performance of particle swarm
optimisation (PSO) algorithm based integral (I) controller and
proportional-integral controller (PI) for interconnected hydro-thermal
automatic generation control (AGC) with generation rate constraint
(GRC) and Thyristor controlled phase shifter (TCPS) in series with
tie line. The control strategy of TCPS provides active control of
system frequency. Conventional objective function integral square
error (ISE) and another objective function considering square of
derivative of change in frequencies of both areas and change in tie
line power are considered. The aim of designing the objective
function is to suppress oscillation in frequency deviations and change
in tie line power oscillation. The controller parameters are searched
by PSO algorithm by minimising the objective functions. The
dynamic performance of the controllers I and PI, for both the
objective functions, are compared with conventionally optimized I
controller.
Abstract: This article describes the information system for
measuring and evaluating the dose rate in the environment of nuclear
power plants Mochovce and Bohunice in Slovakia.
The article presents the results achieved in the implementation of
the EU project – Research of monitoring and evaluation of nonstandard
conditions in the area of nuclear power plants. The
objectives included improving the system of acquisition, measuring
and evaluating data with mobile and autonomous units applying new
knowledge from research.
The article provides basic and specific features of the system and
compared to the previous version of the system, also new functions.
Abstract: In this paper, thick walled Cylindrical tanks or tubes
made of functionally graded material under internal pressure and
temperature gradient are studied. Material parameters have been
considered as power functions. They play important role in the
elastoplastic behavior of these materials. To clarify their role,
different materials with different parameters have been used under
temperature gradient. Finally, their effect and loading effect have
been determined in first yield point. Also, the important role of
temperature gradient was also shown. At the end the study has been
results obtained from changes in the elastic modulus and yield stress.
Also special attention is also given to the effects of this internal
pressure and temperature gradient in the creation of tensile and
compressive stresses.
Abstract: This paper considers the bent and hyper-bent properties
of a class of Boolean functions. For one case, we present a detailed
description for them to be hyper-bent functions, and give a necessary
condition for them to be bent functions for another case.
Abstract: The extracellular proteins secreted by bacteria may be increased in stressful surroundings, such as in the presence of antibiotics. It appears that many antibiotics, when used at low concentrations, have in common the ability to activate or repress gene transcription, which is distinct from their inhibitory effect. There have been comparatively few studies on the potential of antibiotics as a specific chemical signal that can trigger a variety of biological functions. Therefore, this study was carried out to determine the effect of Streptomycin Sulfate in regulating extracellular proteins secreted by Bacillus subtilis ATCC21332. Results of Microdilution assay showed that the Minimum Inhibition Concentration (MIC) of Streptomycin Sulfate on B. subtilis ATCC21332 was 2.5 mg/ml. The bacteria cells were then exposed to Streptomycin Sulfate at concentration of 0.01 MIC before being further incubated for 48h to 72 h. The extracellular proteins secreted were then isolated and analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Proteins profile revealed that three additional bands with approximate sizes of 30 kDa, 22 kDa and 23 kDa were appeared for the treated bacteria with Streptomycin Sulfate. Thus, B. subtilis ATCC21332 in stressful condition with the presence of Streptomycin Sulfate at low concentration could induce the extracellular proteins secretion.
Abstract: Hand grip strength has been utilized as an indicator to evaluate the motor ability of hands, responsible for performing multiple body functions. It is, however, difficult to evaluate other factors (other than hand muscular strength) utilizing the hand grip strength only. In this study, we analyzed the motor ability of hands using EMG and the hand grip strength, simultaneously in order to evaluate concentration, muscular strength reaction time, instantaneous muscular strength change, and agility in response to visual reaction. In results, the average time (and their standard deviations) of muscular strength reaction EMG signal and hand grip strength was found to be 209.6 ± 56.2 ms and 354.3 ± 54.6 ms, respectively. In addition, the onset time which represents acceleration time to reach 90% of maximum hand grip strength, was 382.9 ± 129.9 ms.
Abstract: In this paper, we consider the application of Extreme
Value Theory as a risk measurement tool. The Value at Risk, for a set
of indices, from six Stock Exchanges of Frontier markets is
calculated using the Peaks over Threshold method and the
performance of the model index-wise is evaluated using coverage
tests and loss functions. Our results show that “fattailedness” alone of
the data is not enough to justify the use of EVT as a VaR approach.
The structure of the returns dynamics is also a determining factor.
This approach works fine in markets which have had extremes
occurring in the past thus making the model capable of coping with
extremes coming up (Colombo, Tunisia and Zagreb Stock
Exchanges). On the other hand, we find that indices with lower past
than present volatility fail to adequately deal with future extremes
(Mauritius and Kazakhstan). We also conclude that using EVT alone
produces quite static VaR figures not reflecting the actual dynamics
of the data.
Abstract: This paper presents a regression model for interval type-2 fuzzy sets based on the least squares estimation technique. Unknown coefficients are assumed to be triangular fuzzy numbers. The basic idea is to determine aggregation intervals for type-1 fuzzy sets, membership functions of whose are low membership function and upper membership function of interval type-2 fuzzy set. These aggregation intervals were called weighted intervals. Low and upper membership functions of input and output interval type-2 fuzzy sets for developed regression models are considered as piecewise linear functions.
Abstract: A comprehensive Bayesian analysis has been carried out in the context of informative and non-informative priors for the shape parameter of the Burr type X distribution under different symmetric and asymmetric loss functions. Elicitation of hyperparameter through prior predictive approach is also discussed. Also we derive the expression for posterior predictive distributions, predictive intervals and the credible Intervals. As an illustration, comparisons of these estimators are made through simulation study.
Abstract: The energy-level structure of a pair of electron and positron confined in a quasi-one-dimensional nano-scale potential well has been investigated focusing on its trend in the small limit of confinement strength ω, namely, the Wigner molecular regime. An anisotropic Gaussian-type basis functions supplemented by high angular momentum functions as large as l = 19 has been used to obtain reliable full configuration interaction (FCI) wave functions. The resultant energy spectrum shows a band structure characterized by ω for the large ω regime whereas for the small ω regime it shows an energy-level pattern dominated by excitation into the in-phase motion of the two particles. The observed trend has been rationalized on the basis of the nodal patterns of the FCI wave functions.
Abstract: Electronic markets in recent decades contribute remarkably in business transactions. Many organizations consider traditional ways of trade non-economical and therefore they do trade only through electronic markets. There are different categorizations of electronic markets functions. In one classification, functions of electronic markets are categorized into classes as information, transactions, and value added. In the present paper, effects of the three classes on the two major elements of the supply chain management are measured. The two elements are decrease in the product unit cost and reduction in response time to the customer. The results of the current research show that among nine minor elements related to the three classes of electronic markets functions, six factors and three factors influence on reduction of the product unit cost and reduction of response time to the customer, respectively.
Abstract: The The dynamic economic dispatch (DED) problem is one of the complex constrained optimization problems that have nonlinear, con-convex and non-smooth objective functions. The purpose of the DED is to determine the optimal economic operation of the committed units while meeting the load demand. Associated to this constrained problem there exist highly nonlinear and non-convex practical constraints to be satisfied. Therefore, classical and derivative-based methods are likely not to converge to an optimal or near optimal solution to such a dynamic and large-scale problem. In this paper, an Artificial Immune System technique (AIS) is implemented and applied to solve the DED problem considering the transmission power losses and the valve-point effects in addition to the other operational constraints. To demonstrate the effectiveness of the proposed technique, two case studies are considered. The results obtained using the AIS are compared to those obtained by other methods reported in the literature and found better.
Abstract: The dynamic economic dispatch (DED) problem is one of the complex constrained optimization problems that have nonlinear, con-convex and non-smooth objective functions. The purpose of the DED is to determine the optimal economic operation of the committed units while meeting the load demand. Associated to this constrained problem there exist highly nonlinear and non-convex practical constraints to be satisfied. Therefore, classical and derivative-based methods are likely not to converge to an optimal or near optimal solution to such a dynamic and large-scale problem. In this paper, an Artificial Immune System technique (AIS) is implemented and applied to solve the DED problem considering the transmission power losses and the valve-point effects in addition to the other operational constraints. To demonstrate the effectiveness of the proposed technique, two case studies are considered. The results obtained using the AIS are compared to those obtained by other methods reported in the literature and found better.