Abstract: Today, cancer remains one of the major diseases that
lead to death. The main obstacle in chemotherapy as a main cancer
treatment is the toxicity to normal cells due to Multidrug Resistance
(MDR) after the use of anticancer drugs. Proposed solution to
overcome this problem is the use of MDR efflux inhibitor of cinchona
alkaloids which is delivered together with anticancer drugs
encapsulated in the form of polymeric nanoparticles. The particles
were prepared by the hydration method. The characterization of
nanoparticles was particle size, zeta potential, entrapment efficiency
and in vitro drug release. Combination nanoparticle size ranged 29-45
nm with a neutral surface charge. Entrapment efficiency was above
87% for the use quinine, quinidine or cinchonidine in combination
with etoposide. The release test results exhibited that the cinchona
alkaloids release released faster than that of etoposide. Collectively,
cinchona alkaloids can be packaged along with etoposide in
nanomicelles for better cancer therapy.
Abstract: The purpose of this study was to develop and examine a
Teaching Commitment Scale of Health and Physical Education
(TCS-HPE) for Taiwanese elementary school teachers. First of all,
based on teaching commitment related theory and literatures to
develop a original scale with 40 items, later both stratified random
sampling and cluster sampling were used to sample participants.
During the first stage, 300 teachers were sampled and 251 valid scales
(83.7%) returned. Later, the data was analyzed by exploratory factor
analysis to obtain 74.30% of total variance for the construct validity.
The Cronbach-s alpha coefficient of sum scale reliability was 0.94, and
subscale coefficients were between 0.80 and 0.96. In the second stage,
400 teachers were sampled and 318 valid scales (79.5%) returned.
Finally, this study used confirmatory factor analysis to test validity and
reliability of TCS-HPE. The result showed that the fit indexes reached
acceptable criteria(¤ç2
(246 ) =557.64 , p
Abstract: Two short sediment cores collected from mangrove
areas of Manori and Thane creeks along Mumbai coast were analysed
for sediment composition and metals (Fe, Mn, Cu, Pb, Co, Ni, Zn, Cr
and V). The statistical analysis of Pearson correlation matrix proved
that there is a significant relationship between metal concentration
and finer grain size in Manori creek while poor correlation was
observed in Thane creek. Based on the enrichment factor, the present
metal to background metal ratios clearly reflected maximum
enrichment of Cu and Pb in Manori creek and Mn in Thane creek.
Geoaccumulation index calculated indicate that the study area is
unpolluted with respect to Fe, Mn, Co, Ni, Zn and Cr in both the
cores while moderately polluted with Cu and Pb in Manori creek.
Based on contamination degree, both the core sediments were found
to be considerably contaminated with metals.
Abstract: A novel path planning approach is presented to solve
optimal path in stochastic, time-varying networks under priori traffic
information. Most existing studies make use of dynamic programming
to find optimal path. However, those methods are proved to
be unable to obtain global optimal value, moreover, how to design
efficient algorithms is also another challenge.
This paper employs a decision theoretic framework for defining
optimal path: for a given source S and destination D in urban transit
network, we seek an S - D path of lowest expected travel time
where its link travel times are discrete random variables. To solve
deficiency caused by the methods of dynamic programming, such as
curse of dimensionality and violation of optimal principle, an integer
programming model is built to realize assignment of discrete travel
time variables to arcs. Simultaneously, pruning techniques are also
applied to reduce computation complexity in the algorithm. The final
experiments show the feasibility of the novel approach.
Abstract: Electrocardiogram (ECG) is considered to be the
backbone of cardiology. ECG is composed of P, QRS & T waves and
information related to cardiac diseases can be extracted from the
intervals and amplitudes of these waves. The first step in extracting
ECG features starts from the accurate detection of R peaks in the
QRS complex. We have developed a robust R wave detector using
wavelets. The wavelets used for detection are Daubechies and
Symmetric. The method does not require any preprocessing therefore,
only needs the ECG correct recordings while implementing the
detection. The database has been collected from MIT-BIH arrhythmia
database and the signals from Lead-II have been analyzed. MatLab
7.0 has been used to develop the algorithm. The ECG signal under
test has been decomposed to the required level using the selected
wavelet and the selection of detail coefficient d4 has been done based
on energy, frequency and cross-correlation analysis of decomposition
structure of ECG signal. The robustness of the method is apparent
from the obtained results.
Abstract: During this day a considerable amount of Leachate is produced with high amounts of organic material and nutrients needed plants. This study has done in order to scrutinize the effect of Leachate compost on the pH, EC and organic matter percentage in the form of statistical Factorial plan through randomizing block design with three main and two minor treatments and also three replications during three six month periods. Major treatments include N: Irrigation with the region-s well water as a control, I: Frequent irrigation with well water and Leachate, C: Mixing Leachate and water well (25 percent leachate + 75 percent ordinary well water) and secondary treatments, include DI: surface drip irrigation and SDI: sub surface drip irrigation. Results of this study indicated significant differences between treatments and also there were mixing up with the control treatment in the reduction of pH, increasing soluble salts and also increasing the organic matter percentage. This increase is proportional to the amount of added Leachate and in the treatment also proportional to higher mixture of frequent treatment. Therefore, since creating an acidic pH increases the ability to absorb some nutrient elements such as phosphorus, iron, zinc, copper and manganese are increased and the other hand, organic materials also improve many physical and chemical properties of soil are used in Leachate trash Consider health issues as refined in the green belts around cities as a liquid fertilizer recommended.
Abstract: In the context of global climate change, flooding and sea level rise is increasingly threatening coastal urban areas, in which large population is continuously concentrated. Dutch experiences in urban water system management provide high reference value for sustainable coastal urban development projects. Preliminary studies shows the urban water system in Almere, a typical Dutch polder city, have three kinds of operational modes, achieving functions as: (1) coastline control – strong multiple damming system prevents from storm surges and maintains sufficient capacity upon risks; (2) high flexibility – large area and widely scattered open water system greatly reduce local runoff and water level fluctuation; (3) internal water maintenance – weir and sluice system maintains relatively stable water level, providing excellent boating and landscaping service, coupling with water circulating model maintaining better water quality. Almere has provided plenty of hints and experiences for ongoing development of coastal cities in emerging economies.
Abstract: It is well known that during the developments in the
economic sector and through the financial crises occur everywhere in
the whole world, volatility measurement is the most important
concept in financial time series. Therefore in this paper we discuss
the volatility for Amman stocks market (Jordan) for certain period of
time. Since wavelet transform is one of the most famous filtering
methods and grows up very quickly in the last decade, we compare
this method with the traditional technique, Fast Fourier transform to
decide the best method for analyzing the volatility. The comparison
will be done on some of the statistical properties by using Matlab
program.
Abstract: The world demand for potable water is
increasing every day with growing population. Desalination
using solar energy is suitable for potable water production
from brackish and seawater. In this paper, we present a
theoretical study of solar distillation in a single basin under
the open environmental conditions of Chabahar-Iran. The still
has a base area of 2000mm×500mm with a glass cover
inclined at 25° in order to obtain extra solar energy. We model
the still and conduct its energy balance equations under minor
assumptions. We computed the temperatures of glass cover,
seawater interface, moist air and bottom using numerical
method. The investigation addressed the following: The still
productivity, distilled water salinity and still performance in
terms of the still efficiency. Calculated still productivity in
July was higher than December. So in this paper, we show
that still productivity is directly functioning of solar radiation.
Abstract: The financial crisis has decreased the opportunities of
small businesses to acquire financing through conventional financial
actors, such as commercial banks. This credit constraint is partly the
reason for the emergence of new alternatives of financing, in addition
to the spreading opportunities for communication and secure
financial transfer through Internet. One of the most interesting venues
for finance is termed “crowdfunding". As the term suggests
crowdfunding is an appeal to prospective customers and investors to
form a crowd that will finance projects that otherwise would find it
hard to generate support through the most common financial actors.
Crowdfunding is in this paper divided into different models; the
threshold model, the microfinance model, the micro loan model and
the equity model. All these models add to the financial possibilities of
emerging entrepreneurs.
Abstract: The purpose of this research was to investigate Thai Muslims’ way of life through the way their clothes. The data of this qualitative research were collected from related documents and research reports, ancient cloths and clothing, and in-depth interviews with clothes owners and weavers.
The research found that in the 18th century Thai Muslims in the three southern border provinces used many types of clothing in their life. At home women wore plain clothes. They used checked cloths to cover the upper part of their body from the breasts down to the waist. When going out, they used Lima cloth and So Kae with a piece of Pla-nging cloth as a head scarf. For men, they wore a checked sarong as a lower garment, and wore no upper garment. However, when going out, they wore Puyo Potong. In addition, Thai Muslims used cloths in various religious rites, namely, the rite of placing a baby in a cradle, the Masoyawi rite, the Nikah rite, and the burial rite. These types of cloths were related to the way of life of Thai Muslims from birth to death. They reflected the race, gender, age, social status, values, and beliefs in traditions that have been inherited.
Practical Implication: Woven in these cloths are the lost local wisdom, and therefore, aesthetics on the cloths are like mirrors reflecting the background of people in this region that is fading away. These cloths are pages of a local history book that is of importance and value worth for preservation and publicity so that they are treasured. Government organizations can expand and materialize the knowledge received from the study in accordance with government policy in supporting the One Tambon, One Product project.
Abstract: The emergence of mobile application services and App
Store has led to the explosive growth of user innovation, which users
voluntarily contribute to. User innovation communities where end
users freely reveal innovative ideas and needs with other community
members are becoming increasingly influential in this area. However,
user-s ideas in user innovation community are not enough to be new
service opportunity, because some of them can already developed as
existing services in App Store. Moreover, the existing services similar
to new service opportunity can be significant references to apply
analogy to develop service concept. In response, this research
proposes Case-Based Reasoning approach to matching the user needs
and existing services, identifying unmet opportunistic user needs, and
retrieving similar services with opportunity. Due to its intuitive and
transparent algorithm, users related to App Store innovation
communities can easily employ Case-Based Reasoning based
approach to their innovation.
Abstract: Background: This investigated the mental health of the elderly survivors six months, ten months and two years after the “5.12 Wenchuan" earthquake. Methods: Two hundred and thirty-two physically healthy older survivors from earthquake-affected Mianyang County were interviewed. The measures included the Revised Impact of Event Scale (IES-R, Chinese version, for PTSD) and a Chinese Mental Health Inventory for the Elderly (MHIE). A repeated measures ANOVA test was used for statistical analysis. Results: The follow-up group had a statistically significant lower IES-R score and lower MHIE score than the initial group ten months after the earthquake. Two years later, the score of IES-R in follow-up group were still lower than that of non-follow-up group, but no differences were significant on the score of MHIE between groups. Furthermore, a negative relationship was found between scores of IES-R and MHIE. Conclusion: The earthquake has had a persistent negative impact on older survivors- mental health within the two-year period and that although the PTSD level declined significantly with time, it did not disappear completely.
Abstract: By employing BS (Base Station) cooperation we can
increase substantially the spectral efficiency and capacity of cellular
systems. The signals received at each BS are sent to a central unit that
performs the separation of the different MT (Mobile Terminal) using
the same physical channel. However, we need accurate sampling and
quantization of those signals so as to reduce the backhaul
communication requirements.
In this paper we consider the optimization of the quantizers for BS
cooperation systems. Four different quantizer types are analyzed and
optimized to allow better SQNR (Signal-to-Quantization Noise
Ratio) and BER (Bit Error Rate) performance.
Abstract: Intellectual capital reporting becomes critical at
universities, mainly due to the fact that knowledge is the main output
as well as input in these institutions. In addition, universities have
continuous external demands for greater information and
transparency about the use of public funds, and are increasingly
provided with greater autonomy regarding their organization,
management, and budget allocation. This situation requires new
management and reporting systems. The purpose of the present study
is to provide a model for intellectual capital report in Spanish
universities. To this end, a questionnaire was sent to every member of
the Social Councils of Spanish public universities in order to identify
which intangible elements university stakeholders demand most. Our
proposal for an intellectual capital report aims to act as a guide to
help the Spanish universities on the road to the presentation of
information on intellectual capital which can assist stakeholders to
make the right decisions.
Abstract: An empirical study of web applications that use
software frameworks is presented here. The analysis is based on two
approaches. In the first, developers using such frameworks are
required, based on their experience, to assign weights to parameters
such as database connection. In the second approach, a performance
testing tool, OpenSTA, is used to compute start time and other such
measures. From such an analysis, it is concluded that open source
software is superior to proprietary software. The motivation behind
this research is to examine ways in which a quantitative assessment
can be made of software in general and frameworks in particular.
Concepts such as metrics and architectural styles are discussed along
with previously published research.
Abstract: Median filter is widely used to remove impulse noise
without blurring sharp edges. However, when noise level increased,
or with thin edges, median filter may work poorly. This paper
proposes a new filter, which will detect edges along four possible
directions, and then replace noise corrupted pixel with estimated
noise-free edge median value. Simulations show that the proposed
multi-stage directional median filter can provide excellent
performance of suppressing impulse noise in all situations.
Abstract: The Muslim faith requires individuals to fast between
the hours of sunrise and sunset during the month of Ramadan. Our
recent work has concentrated on some of the changes that take place
during the daytime when fasting. A questionnaire was developed to
assess subjective estimates of physical, mental and social activities,
and fatigue. Four days were studied: in the weeks before and after
Ramadan (control days) and during the first and last weeks of
Ramadan (experimental days). On each of these four days, this
questionnaire was given several times during the daytime and once
after the fast had been broken and just before individuals retired at
night.
During Ramadan, daytime mental, physical and social activities
all decreased below control values but then increased to abovecontrol
values in the evening. The desires to perform physical and
mental activities showed very similar patterns. That is, individuals
tried to conserve energy during the daytime in preparation for the
evenings when they ate and drank, often with friends. During
Ramadan also, individuals were more fatigued in the daytime and
napped more often than on control days. This extra fatigue probably
reflected decreased sleep, individuals often having risen earlier
(before sunrise, to prepare for fasting) and retired later (to enable
recovery from the fast).
Some physiological measures and objective measures of
performance (including the response to a bout of exercise) have also
been investigated. Urine osmolality fell during the daytime on
control days as subjects drank, but rose in Ramadan to reach values
at sunset indicative of dehydration. Exercise performance was also
compromised, particularly late in the afternoon when the fast had
lasted several hours. Self-chosen exercise work-rates fell and a set
amount of exercise felt more arduous. There were also changes in
heart rate and lactate accumulation in the blood, indicative of greater
cardiovascular and metabolic stress caused by the exercise in
subjects who had been fasting. Daytime fasting in Ramadan produces
widespread effects which probably reflect combined effects of sleep
loss and restrictions to intakes of water and food.
Abstract: This paper proposed a novel model for short term load
forecast (STLF) in the electricity market. The prior electricity
demand data are treated as time series. The model is composed of
several neural networks whose data are processed using a wavelet
technique. The model is created in the form of a simulation program
written with MATLAB. The load data are treated as time series data.
They are decomposed into several wavelet coefficient series using
the wavelet transform technique known as Non-decimated Wavelet
Transform (NWT). The reason for using this technique is the belief
in the possibility of extracting hidden patterns from the time series
data. The wavelet coefficient series are used to train the neural
networks (NNs) and used as the inputs to the NNs for electricity load
prediction. The Scale Conjugate Gradient (SCG) algorithm is used as
the learning algorithm for the NNs. To get the final forecast data, the
outputs from the NNs are recombined using the same wavelet
technique. The model was evaluated with the electricity load data of
Electronic Engineering Department in Mandalay Technological
University in Myanmar. The simulation results showed that the
model was capable of producing a reasonable forecasting accuracy in
STLF.
Abstract: Subsurface erosion in river banks and its details, in
spite of its occurrence in various parts of the world has rarely been
paid attention by researchers. In this paper, quantitative concept of
the subsurface bank erosion has been investigated for vertical banks.
Vertical banks were simulated experimentally by considering a sandy
erodible layer overlaid by clayey one under uniformly distributed
constant overhead pressure. Results of the experiments are indicated
that rate of sandy layer erosion is decreased by an increase in
overburden; likewise, substituting 20% of coarse (3.5 mm) sand layer
bed material by fine material (1.4 mm) may lead to a decrease in
erosion rate by one-third. This signifies the importance of the bed
material composition effect on sandy layers erosion due to subsurface
erosion in river banks.