Abstract: Camptothecin (CPT) is a cytotoxic quinoline alkaloid,
which inhibits the DNA enzyme topoisomerase I (topo I). It was
discovered in 1966 by M. E. Wall and M. C. Wani in systematic
screening of natural products for anticancer drugs. It was isolated
from the bark and stem of Camptotheca acuminata (Camptotheca,
Happy tree), a tree native in China. CPT showed remarkable
anticancer activity in preliminary clinical trials but also low
solubility and (high) adverse drug reaction. Because of these
disadvantages synthetic and medicinal chemists have developed
numerous syntheses of Camptothecine [1][2][3] and various
derivatives to increase the benefits of the chemical, with good results.
In our method CPT analogues has be six steps starting from available
material DL Malic acid.
Abstract: Bus Rapid Transit (BRT) has emerged as a cost-effective transport system for urban mobility. However its ability to stimulate land development remains largely unexplored. The study makes use of qualitative (interview method) and quantitative analysis (questionnaire survey and longitudinal analysis of property data) to investigate land development impact resulting from BRT in Beijing, China. The empirical analysis suggests that BRT has a positive impact on the residential and commercial property attractiveness along the busway corridor. The statistical analysis suggests that accessibility advantage conferred by BRT is capitalized into higher property price. The average price of apartments adjacent to a BRT station has gained a relatively faster increase than those not served by the BRT system. The capitalization effect mostly occurs after the full operation of BRT, and is more evident over time and particularly observed in areas which previously lack alternative mobility opportunity.
Abstract: At present, the severe oil crisis and greenhouse effect are booming, which is a growing worry for China. Over a long period of study, choosing the development of biological diesel is a feasible way in the desertification region in China. With considering the adaptability of Micro-algae in desertification region and analyzing energy consumption and carbon calculations of Micro-algae biodiesel produced by JJ company , this paper, make the microalgae our optimal choice to develop biological diesel in china's desertification region.
Abstract: The construction industry is the pillar industry in
China, accounting for about 6% of the gross domestic product. Along
with changes in the external environment of the construction industry
in China, the construction firm faces fierce competition. The paper
aims to investigate the relationship between diversified types of
construction firm and its performance in China. Based on generalist
and specialist strategy in organizational ecology, we think a generalist
organization can be applied to an enterprise with diversified
developments, while specialist groups are extended to professional
enterprises .This study takes advantage of annual financial data of
listed construction firm to empirically verify the relationship between
diversification and corporation performance establishing a regression
equation to econometric analysis. We find that: 1) Specialization can
significantly improve the level of profitability of listed construction
firms, and there is a significant positive relationship with corporate
performance; 2) The level of operating performance of listed
construction enterprises which engage in unrelated diversification is
higher than those with related diversification; 3) The relationship
between state-owned construction firms and corporate performance is
negative. The more the year of foundation is, the higher performance
will be; however, the more the year of being listed, the lower
performance will be.
Abstract: Megalopolis is a group of densely populated metropolitan areas that combine to form an urban complex. Since China introduced the economic reforms in late 1970s, the Chinese urban system has experienced unprecedented growth. The process of urbanisation prevailed in the 1980s, and the process of predominantly large city growth appeared to continue through 1990s and 2000s. In this study, the magnitude and pattern of urbanisation in China during 1990s were examined using remotely sensed imagery acquired by TM/ETM+ sensor onboard the Landsat satellites. The development of megalopolis areas in China was also studied based on the GIS analysis of the increases of urban and built-up area from 1990 to 2000. The analysis suggests that in the traditional agricultural zones in China, e.g., Huang-Huai-Hai Plains, Changjiang River Delta, Pearl River Delta and Sichuan Basin, the urban and built-up areas increased by 1.76 million hectares, of which 0.82 million hectares are expansion of urban areas, an increase of 24.78% compared with 1990 at the national scale. The Yellow River Delta, Changjiang River Delta and Pearl River Delta also saw an increase of urban and built-up area by 63.9%, 66.2% and 83.0% respectively. As a result, three major megalopolises were developed in China: the Guangzhou-Shenzhen-Hong Kong- Macau (Pearl River Delta: PRD) megalopolis area, the Shanghai- Nanjing-Hangzhou (Changjiang River Delta: CRD) megalopolis area and the Beijing-Tianjing-Tangshan-Qinhuangdao (Yellow River Delta-Bohai Sea Ring: YRD) megalopolis area. The relationship between the processed of megalopolisation and the inter-provincial population flow was also explored in the context of social-economic and transport infrastructure development in Post-reform China.
Abstract: This article illustrates that how non similar culture become a cause of constant anxiety among international students in China. For that, a survey was carried out among international students of Wuhan University, China. The association among non similar culture, non familiarity of Chinese culture, self finance students and food problem is looked at through a regression line, and in the light of empirical results, a model is anticipated which elucidates these results. Some suggestions were directed at the end which will help to mitigate the anxiety among prospective students in Chinese universities.
Abstract: This study analyzes characteristics determining
member’s willingness to invest in cooperatives using ordered logit
model. The data were collected in a field survey among 122
cooperative members in north-central China. The descriptive analysis
of survey evidence suggests that cooperatives in China generally
having poor ability to deliver the processing services related to
product package, grading, and storage, performing worse in
profitability, inability of providing returns to capital and obtaining
agricultural loan. The regression results demonstrate that members’
farm size, their satisfaction with cooperative price preferential
services, attitudes toward cooperative operational scale and
development potential have statistically significant impact on
willingness to invest.
Abstract: The wisest economic decision of United States in the
20th century was establishing the favorable international monetary
system, and capturing the leadership position in it. This decision gave
economic hegemony to the US for the next more than 7 decades. The
continuation of this hegemony till the next decade seems difficult as
the US economy is under continuous streams of recessions since
2007. On the other hand, Chinese economy is progressing with a
very fast speed and is estimated to pass the US economy till 2025, in
various aspects. Will the US be able to continue its leadership in the
IMS? Will China replace US in the international monetary system?
The answers to these questions have been explored by comparing the
economic competitiveness of US and China, with respect to each
other. The paper concludes that the change in global economic
environment will compel US to share the leadership of international
monetary system with China. This sharing will solve most problems
of the current IMS, but will also birth some new problems.
Abstract: Understanding how precipitation inter-annually
changes and its implication in agricultural drought and production change in winter wheat (Triticum aestivum L.) growth season is critical for crop production in China. MODIS Temperature-Vegetation Dryness Index (TVDI) and daily mean precipitation time series for the main growth season(Feb. to May) of winter wheat from 2000 to 2010
were used to analyze the distribution of trends of precipitation,
agricultural drought and winter wheat yield change respectively, and
relationships between them in North China region(Huang-huai-hai
region, HHH region), China. The results indicated that the trend of
precipitation in HHH region past 11 years was increasing, which had
induced generally corresponding decreasing trend of agricultural
drought and increasing trend of wheat yield, while the trend of drought
was spatially diverse. The study could provide a basis for agricultural
drought research during winter wheat season in HHH region under the
ground of climate change.
Abstract: This study aims to identify processes, current
situations, and issues of recycling systems for four home appliances,
namely, air conditioners, television receivers, refrigerators, and
washing machines, among e-wastes in China and Japan for
understanding and comparison of their characteristics. In accordance
with results of a literature search, review of information disclosed
online, and questionnaire survey conducted, conclusions of the study
boil down to:
(1)The results show that in Japan most of the home appliances
mentioned above have been collected through home appliance
recycling tickets, resulting in an issue of “requiring some effort" in
treatment and recycling stages, and most plants have contracted out
their e-waste recycling.
(2)It is found out that advantages of the recycling system in Japan
include easiness to monitor concrete data and thorough
environmental friendliness ensured while its disadvantages include
illegal dumping and export. It becomes apparent that advantages of
the recycling system in China include a high reuse rate, low
treatment cost, and fewer illegal dumping while its disadvantages
include less safe reused products, environmental pollution caused by
e-waste treatment, illegal import, and difficulty in obtaining data.
Abstract: Indian telecom services industry has been witnessing
a stupendous growth since 1990s. Over the years, subscriber base has
grown steadily and it crossed 950 million marks in March 2012.
India with second largest subscriber base also offers one of the
lowest call tariffs in the world. But in the euphoria of high growth in
services, the equipment manufacturing received least priority. India
mainly depends on imported components from China. Of late, it is
realized that lack of domestic manufacturing may pose a serious
challenge to India-s continued success in the telecom sector.
Therefore, the National Telecom Policy 2012 aims at developing a
strong equipment manufacturing base within India. This paper
realistically assesses India-s true potential in equipment
manufacturing and seeks to identify the emerging issues and
challenges before the Indian telecom equipment manufacturing sector
while it tries to make a transition from an import-dependent industry
to a global manufacturing hub.
Abstract: This article is devoted to the analysis of results of
sociological researches carried out by authors directed on studying of
opinion of representatives of small, medium and big business on
formation of the Customs Union, Common Free Market Zone with
participation of Kazakhstan, Russia and Belarus.
It-s forecasted that companies, their branches will interpenetrate
with registration and moving their businesses to regions with more
beneficial conditions. They say that in Kazakhstan there are more
profitable geo-strategic operating environment for business and lower
taxes. Russia using this opportunity will create new conditions for
expansion into other countries of Central Asia and China. Opinions
of participants of questionnaire and expert poll different in estimation
of value of these two integration mechanisms since market segments
on the one hand extend, but also on the other hand - loss of exclusive
influence in certain fields of activity.
Abstract: The aim of this paper is to investigate a process of modernization of the People-s Republic of China. The theme of scientific research is interesting, first, because the Chinese model of development is recognized as successful and most dynamically developing. They are obliged by these successes of the modernization spent in the country. Economy modernization as the basic motive power of progress of the country is a priority direction of development in the Republic of Kazakhstan. So the example of successful development modernization processes in China can be rather useful to use in working out of the Kazakhstan national reforms.
Abstract: Postmenopausal osteoporosis is a disorder
characterized by the progressive bone loss induced by estrogen
deficiency in postmenopausal women. This imbalance affects
calcium–phosphate metabolism and results in secondary
hyperparathyroidism. Purariae Radix (PR), the root of P. lobata
(Wild.) Ohwi, is one of the earliest medicinal herbs employed in
ancient China. PR contains a high quantity of isoflavones and their
glycosides, which are regarded as phytoestrogen. Few investigations
of PR are related to its osteoprotective effects. The present study is
designed to administer PR water extract to ovariectomized (OVX)
female rats, for the investigation of its possibly protective actions on
bone and to delineate the potential mechanisms involved. Our results
demonstrated that long-term treatment of PR could not significantly
improve bone properties, whereas it greatly ameliorated the condition
of secondary hyperparathyroidism induced by ovariectomy in those
animals. PR might be useful as alternative regimen for protecting
against postmenopausal bone loss.
Abstract: With China's urbanization continuing to accelerate, a amount of rural people flood into China's cities in recent years, and the issue of agriculture, rural areas and farmers is getting more and more serious. In 2005, the Chinese government put forward a plan for “the construction of new rural village", in order to coordinate the development of both urban and rural areas. The planning method of rural region differs sharply from that of urban areas, as same as village social structure and habits of farmer-s life, so the studies which can consider the special needs of village construction in China are absolutely essential. This paper expresses explore current situation and problems existing in the construction of China-s new rural village, such as bigger gap between urban and rural areas, excessive new construction projects, extinct traditional village style and so on. It tries to analyze the deep reason of the present situation of the village from law system, industrial structure, financial sources and planning method. Then it also provides a guide for developing policies and procedures promoting the development of china-s rural areas.
Abstract: The purpose of this work is to identify the positive and negative aspects of parties- participation in the country-s modernization, which in turn, will help a country to determine the necessary steps to improve the social-economic development. The article considers a question of the role of the dominating party of Kazakhstan and ruling party of China in the country-s modernization. Using a comparative analysis reveals differences between the People's Democratic Party “Nur Otan" and the Communist Party of China. It is discussed the policy of carrying out of modernization, the main actions of political parties of both countries with a view of modernization implementation.
Abstract: Biogas, a clean renewable energy, is attracting a growing
concern of researchers and professionals in many fields. Based
on the natural and climatic conditions in semi-arid regions of northwestern
China, the present study introduces a specifically-designed
family-size biogas plant (with a digester of 10m3) with manure
and urine of animals and humanity as raw materials. The biogas
plant is applicable to areas with altitudes of more than 2000 meters
in northwestern China. In addition to the installation cost, a little
operational expenditure, structure, characteristics, benefits of this
small-scale biogas plant, this article introduces a wide range of
specific popularization methods such as training, financial support,
guided tour to the biogas plant, community-based group study and
delivery of operational manuals. The feasibility of the biogas plant is
explored on the basis of the availability of the raw materials. Simple
operations contained in the current work increase the possibility of
the wide use of this small-scale biogas plant in similar regions of the
world.
Abstract: Accurate evaluation of damping ratios involving soilstructure interaction (SSI) effects is the prerequisite for seismic design of in-situ buildings. This study proposes a combined approach to identify damping ratios of SSI systems based on ambient excitation technique. The proposed approach is illustrated with main test process, sampling principle and algorithm steps through an engineering example, as along with its feasibility and validity. The proposed approach is employed for damping ratio identification of 82 buildings in Xi-an, China. Based on the experimental data, the variation range and tendency of damping ratios of these SSI systems, along with the preliminary influence factor, are shown and discussed. In addition, a fitting curve indicates the relation between the damping ratio and fundamental natural period of SSI system.
Abstract: The number of cross-border student between Hong
Kong and mainland China is increasing due to an increase of
cross-border marriage between Hong Kong and mainland China. Since
the education system is different to the mainland China, the statue
Since all the children who have the right of abode in Hong Kong
entitle to have free education in Hong Kong, many of the cross-border
family prefer to send the children back to Hong Kong for their
education.
Abstract: A hybrid Photovoltaic/Thermal (PV/T) solar system integrates photovoltaic and solar thermal technologies into one single solar energy device, with dual generation of electricity and heat energy. The aim of the present study is to evaluate the potential for introduction of the PV/T technology into Northern China. For this purpose, outdoor experiments were conducted on a prototype of a PV/T water-heating system. The annual thermal and electrical performances were investigated under the climatic conditions of Beijing. An economic analysis of the system was then carried out, followed by a sensitivity study. The analysis revealed that the hybrid system is not economically attractive with the current market and energy prices. However, considering the continuous commitment of the Chinese government towards policy development in the renewable energy sector, and technological improvements like the increasing cost-effectiveness of PV cells, PV/Thermal technology may become economically viable in the near future.